Mus musculus

0 known processes

Efna4

ephrin A4

(Aliases: EFL-4,Epl4,LERK-4)

Efna4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cell fate commitment GO:0045165 210 0.877
embryonic organ morphogenesis GO:0048562 276 0.806
stem cell development GO:0048864 219 0.791
urogenital system development GO:0001655 261 0.790
appendage development GO:0048736 166 0.783
regionalization GO:0003002 337 0.768
regulation of neuron differentiation GO:0045664 281 0.751
regulation of establishment of planar polarity GO:0090175 28 0.738
ear morphogenesis GO:0042471 118 0.732
regulation of cellular amino acid metabolic process GO:0006521 5 0.710
rac protein signal transduction GO:0016601 13 0.704
epithelial tube morphogenesis GO:0060562 303 0.690
axonogenesis GO:0007409 274 0.675
digestive system development GO:0055123 200 0.674
amine metabolic process GO:0009308 45 0.664
neural tube development GO:0021915 160 0.661
trachea cartilage morphogenesis GO:0060535 4 0.660
non canonical wnt signaling pathway GO:0035567 33 0.659
nephron morphogenesis GO:0072028 69 0.655
positive regulation of cell development GO:0010720 237 0.649
leukocyte differentiation GO:0002521 342 0.648
regulation of bmp signaling pathway GO:0030510 60 0.631
striated muscle tissue development GO:0014706 293 0.629
cell fate specification GO:0001708 72 0.626
appendage morphogenesis GO:0035107 149 0.621
regulation of cellular ketone metabolic process GO:0010565 66 0.602
regulation of asymmetric cell division GO:0009786 4 0.600
gland development GO:0048732 330 0.590
embryonic appendage morphogenesis GO:0035113 126 0.583
stem cell maintenance GO:0019827 130 0.581
bmp signaling pathway GO:0030509 93 0.579
neuron projection guidance GO:0097485 141 0.570
negative regulation of bmp signaling pathway GO:0030514 35 0.565
paraxial mesodermal cell differentiation GO:0048342 2 0.552
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.548
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.546
digestive tract morphogenesis GO:0048546 147 0.543
skeletal system development GO:0001501 356 0.541
embryonic limb morphogenesis GO:0030326 126 0.540
male sex differentiation GO:0046661 109 0.527
morphogenesis of a branching epithelium GO:0061138 193 0.527
cell adhesion GO:0007155 329 0.526
gastrulation GO:0007369 116 0.525
regulation of stem cell differentiation GO:2000736 50 0.522
chemotaxis GO:0006935 247 0.513
formation of primary germ layer GO:0001704 77 0.511
epidermis development GO:0008544 187 0.509
negative regulation of cell proliferation GO:0008285 296 0.505
stress activated protein kinase signaling cascade GO:0031098 81 0.500
sensory organ morphogenesis GO:0090596 242 0.499
mesoderm formation GO:0001707 62 0.499
limb morphogenesis GO:0035108 149 0.478
regulation of neuron projection development GO:0010975 169 0.471
endocrine system development GO:0035270 98 0.471
primary neural tube formation GO:0014020 95 0.468
embryonic skeletal system development GO:0048706 120 0.464
cochlea morphogenesis GO:0090103 22 0.461
forebrain development GO:0030900 302 0.460
kidney development GO:0001822 213 0.460
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.456
central nervous system neuron differentiation GO:0021953 162 0.454
mesenchyme development GO:0060485 152 0.452
mesoderm development GO:0007498 100 0.452
nephron epithelium morphogenesis GO:0072088 68 0.450
negative regulation of synapse assembly GO:0051964 3 0.449
metanephric loop of henle development GO:0072236 4 0.445
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.445
nephron tubule development GO:0072080 84 0.441
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.439
skeletal system morphogenesis GO:0048705 203 0.437
sensory perception GO:0007600 245 0.433
axon guidance GO:0007411 141 0.431
embryonic skeletal system morphogenesis GO:0048704 91 0.427
renal system development GO:0072001 225 0.424
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.419
inner ear morphogenesis GO:0042472 101 0.415
blood vessel morphogenesis GO:0048514 285 0.411
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.409
ear development GO:0043583 200 0.406
cellular amine metabolic process GO:0044106 44 0.405
tube formation GO:0035148 140 0.404
embryonic epithelial tube formation GO:0001838 130 0.401
ras protein signal transduction GO:0007265 77 0.394
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.389
morphogenesis of embryonic epithelium GO:0016331 159 0.386
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.382
angiogenesis GO:0001525 201 0.376
hindbrain formation GO:0021576 1 0.373
camera type eye development GO:0043010 266 0.370
cell proliferation in forebrain GO:0021846 30 0.369
hindbrain development GO:0030902 128 0.367
regulation of organ morphogenesis GO:2000027 144 0.362
regulation of epithelial cell proliferation GO:0050678 141 0.361
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.361
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.361
stress activated mapk cascade GO:0051403 80 0.359
central nervous system morphogenesis GO:0021551 2 0.359
nephron epithelium development GO:0072009 92 0.355
morphogenesis of a polarized epithelium GO:0001738 37 0.352
epithelial cell proliferation GO:0050673 174 0.351
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.350
establishment of tissue polarity GO:0007164 28 0.350
mammary gland epithelial cell proliferation GO:0033598 24 0.349
regulation of cellular amine metabolic process GO:0033238 20 0.349
limb development GO:0060173 166 0.334
nephron development GO:0072006 109 0.333
regulation of transforming growth factor beta2 production GO:0032909 2 0.332
digestive tract development GO:0048565 190 0.329
establishment of organ orientation GO:0048561 1 0.329
central nervous system vasculogenesis GO:0022009 3 0.328
development of primary male sexual characteristics GO:0046546 88 0.327
hypophysis morphogenesis GO:0048850 3 0.327
ureteric bud development GO:0001657 94 0.324
mesonephric epithelium development GO:0072163 94 0.321
nephron tubule morphogenesis GO:0072078 68 0.320
axis elongation involved in somitogenesis GO:0090245 4 0.319
mesonephric tubule formation GO:0072172 11 0.319
kidney morphogenesis GO:0060993 83 0.318
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.315
developmental maturation GO:0021700 193 0.312
hematopoietic stem cell proliferation GO:0071425 13 0.312
positive regulation of neuron differentiation GO:0045666 141 0.308
embryonic digit morphogenesis GO:0042733 56 0.305
positive regulation of protein modification process GO:0031401 299 0.304
neural tube closure GO:0001843 90 0.301
cell cell signaling involved in cell fate commitment GO:0045168 35 0.301
epithelial cell development GO:0002064 159 0.299
positive regulation of anagen GO:0051885 1 0.297
lymphocyte differentiation GO:0030098 242 0.297
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.296
lung induction GO:0060492 3 0.296
regulation of mapk cascade GO:0043408 248 0.295
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.295
single organismal cell cell adhesion GO:0016337 131 0.295
muscular septum morphogenesis GO:0003150 4 0.294
t cell differentiation GO:0030217 174 0.292
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.291
polarity specification of proximal distal axis GO:0010085 2 0.289
mesodermal cell fate commitment GO:0001710 17 0.289
mesoderm morphogenesis GO:0048332 64 0.283
ventral spinal cord interneuron differentiation GO:0021514 16 0.282
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.280
negative regulation of molecular function GO:0044092 258 0.278
morphogenesis of a branching structure GO:0001763 203 0.278
negative regulation of nervous system development GO:0051961 156 0.277
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.276
regulation of muscle tissue development GO:1901861 97 0.276
cardiocyte differentiation GO:0035051 87 0.274
b cell activation GO:0042113 161 0.273
positive regulation of lymphocyte activation GO:0051251 140 0.269
cardiac muscle tissue development GO:0048738 130 0.268
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.267
male gonad development GO:0008584 88 0.266
cardiac chamber development GO:0003205 108 0.266
negative regulation of prostatic bud formation GO:0060686 4 0.265
forelimb morphogenesis GO:0035136 40 0.264
positive regulation of mapk cascade GO:0043410 170 0.263
subpallium neuron fate commitment GO:0060163 2 0.263
mesenchymal cell differentiation GO:0048762 107 0.262
endodermal cell fate specification GO:0001714 4 0.261
positive regulation of apoptotic process GO:0043065 217 0.259
positive regulation of nervous system development GO:0051962 221 0.259
oviduct development GO:0060066 3 0.258
midbrain hindbrain boundary maturation GO:0021732 1 0.258
respiratory system development GO:0060541 190 0.257
cartilage development GO:0051216 140 0.257
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.255
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.254
ribonucleotide metabolic process GO:0009259 291 0.253
renal vesicle induction GO:0072034 3 0.252
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.250
branching morphogenesis of an epithelial tube GO:0048754 159 0.249
prostate gland morphogenesis GO:0060512 32 0.248
spermatogenesis GO:0007283 284 0.248
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.247
wnt signaling pathway GO:0016055 188 0.246
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.245
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.243
branching involved in ureteric bud morphogenesis GO:0001658 56 0.242
mammary gland epithelium development GO:0061180 65 0.241
mesenchymal cell development GO:0014031 93 0.239
positive regulation of interleukin 8 secretion GO:2000484 1 0.239
establishment of anatomical structure orientation GO:0048560 1 0.237
renal tubule morphogenesis GO:0061333 72 0.237
telencephalon development GO:0021537 186 0.235
cardiac chamber morphogenesis GO:0003206 93 0.232
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.231
mapk cascade GO:0000165 281 0.231
hair cycle GO:0042633 90 0.231
muscle tissue development GO:0060537 308 0.230
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.230
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.230
mesodermal cell differentiation GO:0048333 22 0.229
stem cell differentiation GO:0048863 268 0.229
artery development GO:0060840 53 0.228
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.228
mammary gland morphogenesis GO:0060443 54 0.228
regulation of protein serine threonine kinase activity GO:0071900 157 0.228
regulation of cell projection organization GO:0031344 206 0.228
regulation of jun kinase activity GO:0043506 40 0.221
limbic system development GO:0021761 72 0.221
maintenance of cell number GO:0098727 3 0.221
peptidyl amino acid modification GO:0018193 336 0.220
regulation of anagen GO:0051884 1 0.219
mesonephric duct morphogenesis GO:0072180 4 0.219
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.217
rho protein signal transduction GO:0007266 32 0.217
renal outer medulla development GO:0072054 2 0.215
negative regulation of cell development GO:0010721 169 0.215
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.214
leukocyte proliferation GO:0070661 172 0.214
cranial nerve morphogenesis GO:0021602 26 0.214
kidney epithelium development GO:0072073 121 0.214
axis elongation GO:0003401 30 0.213
cardiac right atrium morphogenesis GO:0003213 3 0.212
small gtpase mediated signal transduction GO:0007264 97 0.211
cellular response to growth factor stimulus GO:0071363 197 0.211
negative regulation of neuron differentiation GO:0045665 101 0.211
establishment or maintenance of cell polarity GO:0007163 86 0.210
tube closure GO:0060606 91 0.207
olfactory bulb interneuron differentiation GO:0021889 12 0.207
neural tube formation GO:0001841 108 0.206
heart morphogenesis GO:0003007 178 0.204
establishment of planar polarity GO:0001736 28 0.203
testosterone biosynthetic process GO:0061370 2 0.203
nephron tubule formation GO:0072079 20 0.203
mesonephric tubule morphogenesis GO:0072171 63 0.202
neuron maturation GO:0042551 29 0.202
cranial nerve development GO:0021545 41 0.200
negative regulation of ovulation GO:0060280 1 0.198
regulation of cellular response to growth factor stimulus GO:0090287 82 0.197
androgen biosynthetic process GO:0006702 4 0.197
renal inner medulla development GO:0072053 3 0.196
spemann organizer formation GO:0060061 2 0.195
ureteric bud morphogenesis GO:0060675 62 0.193
canonical wnt signaling pathway GO:0060070 130 0.192
regulation of canonical wnt signaling pathway GO:0060828 82 0.192
apoptotic signaling pathway GO:0097190 306 0.192
positive regulation of protein phosphorylation GO:0001934 242 0.191
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.189
regulation of cellular response to stress GO:0080135 159 0.188
locomotory behavior GO:0007626 195 0.187
response to parathyroid hormone GO:0071107 3 0.186
palate development GO:0060021 76 0.186
autonomic nervous system development GO:0048483 43 0.184
nucleotide metabolic process GO:0009117 332 0.184
paraxial mesodermal cell fate commitment GO:0048343 2 0.184
somatic stem cell maintenance GO:0035019 47 0.183
renal tubule development GO:0061326 87 0.182
blastocyst development GO:0001824 80 0.181
muscle cell differentiation GO:0042692 261 0.180
cellular amino acid metabolic process GO:0006520 103 0.178
regulation of cell cycle GO:0051726 281 0.178
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.178
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.177
connective tissue development GO:0061448 179 0.176
motor neuron axon guidance GO:0008045 26 0.175
pituitary gland development GO:0021983 38 0.174
somatotropin secreting cell differentiation GO:0060126 4 0.173
regulation of jnk cascade GO:0046328 62 0.173
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.172
odontogenesis GO:0042476 78 0.171
epithelial tube formation GO:0072175 130 0.170
olfactory bulb interneuron development GO:0021891 7 0.169
positive regulation of cell activation GO:0050867 158 0.168
cellular ketone metabolic process GO:0042180 84 0.168
regulation of epithelial to mesenchymal transition GO:0010717 22 0.166
negative regulation of protein metabolic process GO:0051248 282 0.164
positive regulation of cellular amine metabolic process GO:0033240 5 0.164
lung field specification GO:0060424 3 0.164
macromolecule catabolic process GO:0009057 281 0.163
regulation of wnt signaling pathway GO:0030111 123 0.163
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.162
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.161
syncytium formation by plasma membrane fusion GO:0000768 42 0.161
spinal cord ventral commissure morphogenesis GO:0021965 2 0.160
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.160
mesonephric duct formation GO:0072181 2 0.159
nephric duct formation GO:0072179 4 0.159
kidney rudiment formation GO:0072003 3 0.159
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.158
placenta development GO:0001890 140 0.157
germ cell development GO:0007281 185 0.157
neuron fate specification GO:0048665 30 0.157
hippocampus development GO:0021766 52 0.155
lens development in camera type eye GO:0002088 62 0.155
response to transforming growth factor beta GO:0071559 88 0.154
axial mesoderm formation GO:0048320 3 0.152
regulation of apoptotic signaling pathway GO:2001233 197 0.150
cell substrate adhesion GO:0031589 130 0.149
outflow tract morphogenesis GO:0003151 53 0.148
regulation of cartilage development GO:0061035 44 0.148
cell division GO:0051301 120 0.148
regulation of stress activated mapk cascade GO:0032872 69 0.147
regulation of testosterone biosynthetic process GO:2000224 2 0.147
positive regulation of map kinase activity GO:0043406 84 0.146
somite development GO:0061053 81 0.146
regulation of protein kinase activity GO:0045859 232 0.146
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.144
epithelium migration GO:0090132 63 0.144
trophectodermal cell differentiation GO:0001829 21 0.144
forebrain morphogenesis GO:0048853 17 0.143
lung development GO:0030324 164 0.142
specification of organ identity GO:0010092 30 0.142
regulation of kinase activity GO:0043549 249 0.141
neural tube patterning GO:0021532 43 0.140
embryonic placenta development GO:0001892 98 0.139
cell maturation GO:0048469 127 0.137
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.137
ventricular septum morphogenesis GO:0060412 27 0.137
cell differentiation in spinal cord GO:0021515 53 0.135
female gonad development GO:0008585 71 0.135
t cell activation GO:0042110 289 0.135
convergent extension involved in organogenesis GO:0060029 7 0.134
male gamete generation GO:0048232 285 0.134
skin development GO:0043588 220 0.133
midbrain hindbrain boundary development GO:0030917 9 0.133
pallium development GO:0021543 120 0.133
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.132
tongue development GO:0043586 18 0.132
negative regulation of testosterone biosynthetic process GO:2000225 1 0.132
skeletal muscle organ development GO:0060538 163 0.131
gonad development GO:0008406 141 0.130
forebrain regionalization GO:0021871 25 0.129
development of primary female sexual characteristics GO:0046545 73 0.128
single organism cell adhesion GO:0098602 156 0.128
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.128
spinal cord development GO:0021510 81 0.127
regulation of cellular catabolic process GO:0031329 242 0.127
citrulline biosynthetic process GO:0019240 2 0.127
middle ear morphogenesis GO:0042474 23 0.126
forebrain neuron differentiation GO:0021879 52 0.126
tissue regeneration GO:0042246 22 0.125
mesonephric tubule development GO:0072164 94 0.125
central nervous system projection neuron axonogenesis GO:0021952 21 0.124
negative regulation of execution phase of apoptosis GO:1900118 4 0.124
female gamete generation GO:0007292 74 0.123
spleen development GO:0048536 39 0.122
negative regulation of wnt signaling pathway GO:0030178 73 0.122
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.122
positive regulation of jnk cascade GO:0046330 46 0.122
cerebellum formation GO:0021588 1 0.121
central nervous system neuron development GO:0021954 67 0.120
cardiac ventricle development GO:0003231 83 0.120
positive regulation of leukocyte differentiation GO:1902107 86 0.119
negative regulation of androgen biosynthetic process GO:2000180 1 0.118
protein maturation GO:0051604 176 0.118
cell type specific apoptotic process GO:0097285 268 0.118
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.118
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.117
regulation of peptidase activity GO:0052547 96 0.117
inner medullary collecting duct development GO:0072061 2 0.117
developmental growth involved in morphogenesis GO:0060560 138 0.116
mesonephros development GO:0001823 97 0.116
metanephros development GO:0001656 79 0.116
epithelial to mesenchymal transition GO:0001837 47 0.116
development of primary sexual characteristics GO:0045137 143 0.116
regulation of ossification GO:0030278 112 0.115
somitogenesis GO:0001756 69 0.114
regulation of neuron apoptotic process GO:0043523 122 0.114
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.114
cardiac muscle tissue morphogenesis GO:0055008 44 0.114
ventral spinal cord interneuron fate commitment GO:0060579 14 0.113
respiratory tube development GO:0030323 167 0.112
keratinocyte differentiation GO:0030216 48 0.112
cardiac septum development GO:0003279 59 0.112
regulation of protein localization GO:0032880 231 0.112
dna metabolic process GO:0006259 303 0.111
positive regulation of stem cell proliferation GO:2000648 59 0.111
positive regulation of jun kinase activity GO:0043507 30 0.111
regulation of cell activation GO:0050865 289 0.111
negative regulation of neuron projection regeneration GO:0070571 3 0.111
negative regulation of cellular protein metabolic process GO:0032269 247 0.110
sensory organ boundary specification GO:0008052 1 0.110
establishment of endothelial blood brain barrier GO:0014045 3 0.109
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.109
myeloid leukocyte differentiation GO:0002573 119 0.109
neural crest cell differentiation GO:0014033 54 0.108
outer medullary collecting duct development GO:0072060 1 0.106
metanephric nephron epithelium development GO:0072243 19 0.106
negative regulation of epithelial cell proliferation GO:0050680 64 0.106
heterocycle catabolic process GO:0046700 280 0.105
positive regulation of cell death GO:0010942 224 0.105
central nervous system segmentation GO:0035283 3 0.104
neuroepithelial cell differentiation GO:0060563 37 0.102
protein citrullination GO:0018101 2 0.102
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.100
regulation of organ formation GO:0003156 34 0.100
regulation of protein transport GO:0051223 163 0.100
regulation of kidney development GO:0090183 40 0.100
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.100
regulation of map kinase activity GO:0043405 120 0.100
regulation of interleukin 8 secretion GO:2000482 2 0.099
regulation of fibroblast growth factor production GO:0090270 4 0.099
ossification GO:0001503 216 0.099
foregut regionalization GO:0060423 3 0.098
t cell differentiation in thymus GO:0033077 77 0.098
meiotic cell cycle GO:0051321 122 0.098
positive regulation of protein kinase activity GO:0045860 144 0.098
embryonic heart tube morphogenesis GO:0003143 51 0.097
regulation of synapse assembly GO:0051963 29 0.097
regulation of establishment of protein localization GO:0070201 181 0.097
response to growth factor GO:0070848 198 0.097
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.097
cell cell junction organization GO:0045216 72 0.096
metanephric nephron development GO:0072210 34 0.095
regulation of peptidyl serine phosphorylation GO:0033135 39 0.095
exocrine system development GO:0035272 45 0.094
negative regulation of hormone metabolic process GO:0032351 4 0.094
myeloid cell differentiation GO:0030099 233 0.092
prostate gland epithelium morphogenesis GO:0060740 31 0.092
segmentation GO:0035282 93 0.092
synaptic transmission GO:0007268 329 0.092
cellular response to parathyroid hormone stimulus GO:0071374 2 0.091
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.091
positive regulation of actin filament bundle assembly GO:0032233 11 0.091
positive regulation of intracellular transport GO:0032388 70 0.090
negative regulation of cell fate specification GO:0009996 4 0.090
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.090
protein processing GO:0016485 163 0.090
cochlea development GO:0090102 35 0.090
convergent extension GO:0060026 14 0.089
spinal cord association neuron differentiation GO:0021527 14 0.088
notochord development GO:0030903 20 0.088
jnk cascade GO:0007254 72 0.088
negative regulation of cartilage development GO:0061037 17 0.088
female sex determination GO:0030237 1 0.088
cardiac muscle cell differentiation GO:0055007 69 0.088
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.088
regulation of neuron death GO:1901214 134 0.088
cardiac epithelial to mesenchymal transition GO:0060317 18 0.087
positive regulation of programmed cell death GO:0043068 218 0.087
cell matrix adhesion GO:0007160 68 0.086
diencephalon development GO:0021536 63 0.086
carbohydrate homeostasis GO:0033500 128 0.085
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.085
cell fate determination GO:0001709 32 0.084
uterus morphogenesis GO:0061038 2 0.084
bone morphogenesis GO:0060349 78 0.083
response to extracellular stimulus GO:0009991 127 0.083
ameboidal type cell migration GO:0001667 128 0.083
negative regulation of hepatocyte differentiation GO:0070367 1 0.083
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.083
positive regulation of t cell activation GO:0050870 101 0.083
positive regulation of t cell differentiation GO:0045582 52 0.082
lens morphogenesis in camera type eye GO:0002089 24 0.082
skeletal muscle cell differentiation GO:0035914 66 0.082
forebrain neuron development GO:0021884 30 0.081
adult locomotory behavior GO:0008344 91 0.081
positive regulation of cell migration GO:0030335 109 0.081
regulation of rho protein signal transduction GO:0035023 71 0.081
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.081
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.080
hindbrain morphogenesis GO:0021575 46 0.080
t cell apoptotic process GO:0070231 39 0.080
forebrain radial glial cell differentiation GO:0021861 4 0.080
dorsal spinal cord development GO:0021516 20 0.079
type b pancreatic cell proliferation GO:0044342 10 0.079
embryonic genitalia morphogenesis GO:0030538 4 0.079
syncytium formation GO:0006949 43 0.078
adult behavior GO:0030534 135 0.078
pyramidal neuron migration GO:0021852 1 0.078
body morphogenesis GO:0010171 45 0.078
regulation of endopeptidase activity GO:0052548 89 0.078
odontogenesis of dentin containing tooth GO:0042475 66 0.077
cardiac septum morphogenesis GO:0060411 46 0.077
cilium assembly GO:0042384 81 0.076
b cell differentiation GO:0030183 78 0.076
positive regulation of endopeptidase activity GO:0010950 43 0.076
neurohypophysis development GO:0021985 2 0.076
positive regulation of epithelial cell proliferation GO:0050679 68 0.076
paramesonephric duct development GO:0061205 3 0.076
regulation of cell migration GO:0030334 219 0.075
glandular epithelial cell differentiation GO:0002067 38 0.075
negative regulation of gastrulation GO:2000542 3 0.075
endocrine pancreas development GO:0031018 29 0.075
retinal ganglion cell axon guidance GO:0031290 18 0.075
regulation of cell substrate adhesion GO:0010810 73 0.074
modification dependent macromolecule catabolic process GO:0043632 133 0.074
organ induction GO:0001759 21 0.074
regulation of intracellular transport GO:0032386 159 0.074
fasciculation of motor neuron axon GO:0097156 2 0.074
regulation of ketone biosynthetic process GO:0010566 2 0.074
positive regulation of mesoderm development GO:2000382 2 0.073
type b pancreatic cell differentiation GO:0003309 13 0.073
cell fate specification involved in pattern specification GO:0060573 11 0.073
columnar cuboidal epithelial cell development GO:0002066 29 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.073
negative regulation of alcohol biosynthetic process GO:1902931 4 0.073
post anal tail morphogenesis GO:0036342 23 0.073
forebrain generation of neurons GO:0021872 63 0.073
regulation of embryonic development GO:0045995 71 0.073
regulation of catenin import into nucleus GO:0035412 5 0.073
developmental induction GO:0031128 34 0.073
fasciculation of sensory neuron axon GO:0097155 3 0.072
embryonic nail plate morphogenesis GO:0035880 3 0.072
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.072
maintenance of location GO:0051235 89 0.072
hair follicle development GO:0001942 85 0.071
ventricular septum development GO:0003281 42 0.071

Efna4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org