Mus musculus

274 known processes

Efna1

ephrin A1

(Aliases: B61,Epl1,Eplg1,AI325262,Efl1,Lerk1)

Efna1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukocyte differentiation GO:0002521 342 0.830
Mouse
t cell activation GO:0042110 289 0.826
Mouse
angiogenesis GO:0001525 201 0.792
axon target recognition GO:0007412 4 0.721
lymphocyte differentiation GO:0030098 242 0.717
t cell differentiation in thymus GO:0033077 77 0.632
regulation of ras gtpase activity GO:0032318 88 0.616
Mouse
immune effector process GO:0002252 321 0.589
regulation of rho gtpase activity GO:0032319 58 0.581
Mouse
mapk cascade GO:0000165 281 0.569
activation of rac gtpase activity GO:0032863 2 0.532
embryonic organ morphogenesis GO:0048562 276 0.529
positive regulation of cell activation GO:0050867 158 0.527
Mouse
myeloid leukocyte activation GO:0002274 83 0.525
regulation of cellular amine metabolic process GO:0033238 20 0.522
cellular amine metabolic process GO:0044106 44 0.499
cell cell recognition GO:0009988 44 0.488
muscle cell differentiation GO:0042692 261 0.456
Mouse
regulation of hydrolase activity GO:0051336 246 0.452
Mouse
rho protein signal transduction GO:0007266 32 0.430
t cell differentiation GO:0030217 174 0.429
positive regulation of cellular catabolic process GO:0031331 148 0.422
positive regulation of t cell activation GO:0050870 101 0.422
Mouse
regulation of cell migration GO:0030334 219 0.421
cellular amino acid metabolic process GO:0006520 103 0.404
positive regulation of rac gtpase activity GO:0032855 14 0.393
purine nucleoside metabolic process GO:0042278 241 0.384
Mouse
chemotaxis GO:0006935 247 0.374
Mouse
t cell proliferation GO:0042098 120 0.372
Mouse
ribonucleoside catabolic process GO:0042454 206 0.368
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.351
Mouse
regulation of cellular catabolic process GO:0031329 242 0.349
Mouse
adaptive immune response GO:0002250 155 0.348
cell activation involved in immune response GO:0002263 126 0.342
blood vessel endothelial cell migration GO:0043534 23 0.341
amine metabolic process GO:0009308 45 0.337
regulation of gtp catabolic process GO:0033124 113 0.329
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.327
positive regulation of protein modification process GO:0031401 299 0.324
regulation of cellular amino acid metabolic process GO:0006521 5 0.319
small gtpase mediated signal transduction GO:0007264 97 0.316
myeloid cell activation involved in immune response GO:0002275 34 0.314
positive regulation of nucleoside metabolic process GO:0045979 91 0.312
positive regulation of ras gtpase activity GO:0032320 65 0.311
activation of mapk activity involved in innate immune response GO:0035419 2 0.310
regulation of gliogenesis GO:0014013 50 0.305
positive regulation of protein kinase activity GO:0045860 144 0.303
regulation of t cell proliferation GO:0042129 92 0.300
Mouse
blood circulation GO:0008015 195 0.299
regulation of neuron differentiation GO:0045664 281 0.297
cellular ketone metabolic process GO:0042180 84 0.297
positive regulation of rho gtpase activity GO:0032321 41 0.292
organophosphate catabolic process GO:0046434 232 0.290
Mouse
regulation of vasculature development GO:1901342 88 0.288
skeletal muscle organ development GO:0060538 163 0.286
positive regulation of mapk cascade GO:0043410 170 0.285
regulation of purine nucleotide catabolic process GO:0033121 122 0.280
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.275
action potential GO:0001508 78 0.273
gtp catabolic process GO:0006184 143 0.272
Mouse
pallium development GO:0021543 120 0.271
single organismal cell cell adhesion GO:0016337 131 0.269
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.262
Mouse
regulation of cell activation GO:0050865 289 0.258
Mouse
neuron projection guidance GO:0097485 141 0.257
Mouse
alpha beta t cell activation GO:0046631 91 0.256
leukocyte activation involved in immune response GO:0002366 126 0.252
actin cytoskeleton organization GO:0030036 220 0.250
Mouse
positive regulation of thymocyte migration GO:2000412 2 0.250
regulation of angiogenesis GO:0045765 81 0.245
regulation of protein kinase activity GO:0045859 232 0.240
regulation of mapk cascade GO:0043408 248 0.238
ras protein signal transduction GO:0007265 77 0.237
axon guidance GO:0007411 141 0.233
Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.232
Mouse
nucleoside catabolic process GO:0009164 206 0.230
Mouse
alpha beta t cell proliferation GO:0046633 21 0.230
telencephalon development GO:0021537 186 0.227
ameboidal type cell migration GO:0001667 128 0.226
circulatory system process GO:0003013 197 0.225
locomotory behavior GO:0007626 195 0.224
Mouse
camera type eye development GO:0043010 266 0.224
nucleotide catabolic process GO:0009166 217 0.223
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.222
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.217
nucleoside metabolic process GO:0009116 246 0.216
Mouse
regulation of response to wounding GO:1903034 189 0.216
ribose phosphate metabolic process GO:0019693 291 0.214
Mouse
regulation of actin cytoskeleton organization GO:0032956 84 0.212
Mouse
notochord formation GO:0014028 5 0.211
gtp metabolic process GO:0046039 144 0.208
Mouse
establishment of lymphocyte polarity GO:0001767 2 0.196
purine nucleotide catabolic process GO:0006195 211 0.196
Mouse
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.193
immune response regulating signaling pathway GO:0002764 125 0.192
purine nucleoside triphosphate metabolic process GO:0009144 226 0.191
Mouse
cerebral cortex cell migration GO:0021795 44 0.191
response to growth factor GO:0070848 198 0.189
neural precursor cell proliferation GO:0061351 121 0.188
negative thymic t cell selection GO:0045060 12 0.188
localization within membrane GO:0051668 4 0.188
cellular extravasation GO:0045123 17 0.188
synaptic transmission GO:0007268 329 0.187
negative regulation of cell proliferation GO:0008285 296 0.185
Mouse
peptidyl amino acid modification GO:0018193 336 0.184
negative regulation of cell development GO:0010721 169 0.184
heart contraction GO:0060047 93 0.183
thymic t cell selection GO:0045061 22 0.179
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.176
forebrain cell migration GO:0021885 58 0.176
muscular septum morphogenesis GO:0003150 4 0.174
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.174
engulfment of apoptotic cell GO:0043652 3 0.172
guanosine containing compound catabolic process GO:1901069 144 0.168
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.168
Mouse
regulation of transferase activity GO:0051338 263 0.167
regulation of nucleoside metabolic process GO:0009118 130 0.166
Mouse
cell recognition GO:0008037 83 0.166
Mouse
positive regulation of phagocytosis GO:0050766 26 0.164
cytoplasmic transport GO:0016482 234 0.161
regulation of membrane potential GO:0042391 192 0.161
blood vessel morphogenesis GO:0048514 285 0.160
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.160
retinal ganglion cell axon guidance GO:0031290 18 0.158
Mouse
activation of immune response GO:0002253 138 0.157
epidermis development GO:0008544 187 0.155
Worm
regulation of protein serine threonine kinase activity GO:0071900 157 0.155
ephrin receptor signaling pathway GO:0048013 20 0.155
myeloid dendritic cell activation involved in immune response GO:0002277 2 0.155
cell chemotaxis GO:0060326 81 0.155
immune response activating signal transduction GO:0002757 116 0.154
nucleoside triphosphate metabolic process GO:0009141 230 0.152
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.152
divalent metal ion transport GO:0070838 172 0.152
cellular response to cytokine stimulus GO:0071345 189 0.151
g protein coupled receptor signaling pathway GO:0007186 243 0.151
ensheathment of neurons GO:0007272 76 0.149
purine containing compound catabolic process GO:0072523 213 0.147
Mouse
cerebral cortex development GO:0021987 86 0.147
septum primum development GO:0003284 4 0.147
cytokine metabolic process GO:0042107 71 0.146
forebrain development GO:0030900 302 0.146
regulation of t cell activation GO:0050863 170 0.146
Mouse
cellular homeostasis GO:0019725 240 0.146
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.145
Mouse
regulation of secretion GO:0051046 274 0.145
Mouse
nucleotide metabolic process GO:0009117 332 0.143
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.142
Mouse
regulation of lymphocyte activation GO:0051249 240 0.140
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.140
positive regulation of gtp catabolic process GO:0033126 85 0.140
regulation of nucleotide metabolic process GO:0006140 169 0.140
Mouse
membrane organization GO:0061024 245 0.139
positive regulation of nucleotide metabolic process GO:0045981 114 0.139
plasma membrane organization GO:0007009 90 0.137
leukocyte migration GO:0050900 124 0.137
regulation of monocyte extravasation GO:2000437 2 0.135
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.135
regulation of purine nucleotide metabolic process GO:1900542 169 0.134
Mouse
stem cell development GO:0048864 219 0.134
regulation of nucleotide catabolic process GO:0030811 122 0.132
Mouse
regulation of actin filament based process GO:0032970 99 0.132
Mouse
aortic valve morphogenesis GO:0003180 4 0.132
ossification GO:0001503 216 0.132
mitral valve morphogenesis GO:0003183 4 0.131
regulation of t cell extravasation GO:2000407 3 0.131
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.130
heterocycle catabolic process GO:0046700 280 0.129
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.128
kidney development GO:0001822 213 0.127
positive regulation of map kinase activity GO:0043406 84 0.127
fasciculation of sensory neuron axon GO:0097155 3 0.126
regulation of adaptive immune response GO:0002819 90 0.126
regulation of neuron death GO:1901214 134 0.126
wound healing GO:0042060 157 0.124
carbohydrate derivative catabolic process GO:1901136 231 0.124
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.123
positive regulation of gtpase activity GO:0043547 85 0.123
regulation of cellular component biogenesis GO:0044087 181 0.123
negative regulation of nervous system development GO:0051961 156 0.123
actin filament organization GO:0007015 113 0.122
phospholipid metabolic process GO:0006644 87 0.122
glycosyl compound catabolic process GO:1901658 206 0.122
Mouse
activation of rho gtpase activity GO:0032862 7 0.121
positive regulation of cell development GO:0010720 237 0.120
regulation of glial cell differentiation GO:0045685 41 0.120
ascending aorta development GO:0035905 3 0.120
tricuspid valve development GO:0003175 3 0.120
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.119
Mouse
epithelial tube morphogenesis GO:0060562 303 0.118
innate immune response GO:0045087 157 0.118
t cell selection GO:0045058 34 0.118
regulation of cell motility GO:2000145 236 0.116
ribonucleotide catabolic process GO:0009261 208 0.115
Mouse
monocyte extravasation GO:0035696 2 0.115
divalent inorganic cation transport GO:0072511 178 0.115
urogenital system development GO:0001655 261 0.114
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.114
positive regulation of epithelial cell proliferation GO:0050679 68 0.114
cytokine production GO:0001816 319 0.113
regulation of rho protein signal transduction GO:0035023 71 0.113
Mouse
neuron apoptotic process GO:0051402 142 0.112
cytokine biosynthetic process GO:0042089 68 0.112
skeletal system development GO:0001501 356 0.112
positive regulation of striated muscle cell differentiation GO:0051155 35 0.112
Mouse
cell migration involved in sprouting angiogenesis GO:0002042 9 0.112
sequestering of metal ion GO:0051238 19 0.111
wnt signaling pathway GO:0016055 188 0.109
regulation of protein localization GO:0032880 231 0.109
regulation of cellular ketone metabolic process GO:0010565 66 0.108
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.107
bundle of his development GO:0003166 4 0.107
regulation of organelle organization GO:0033043 289 0.106
Mouse
protein localization to organelle GO:0033365 185 0.106
negative regulation of cellular component organization GO:0051129 194 0.106
striated muscle tissue development GO:0014706 293 0.106
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.105
positive regulation of nervous system development GO:0051962 221 0.105
purine ribonucleotide catabolic process GO:0009154 208 0.104
Mouse
telencephalon cell migration GO:0022029 55 0.104
negative regulation of cell migration GO:0030336 59 0.104
myeloid leukocyte differentiation GO:0002573 119 0.104
Mouse
positive regulation of immunological synapse formation GO:2000522 1 0.102
organonitrogen compound catabolic process GO:1901565 264 0.102
Mouse
heart morphogenesis GO:0003007 178 0.101
lymphocyte proliferation GO:0046651 164 0.101
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.101
Mouse
inner ear morphogenesis GO:0042472 101 0.101
positive regulation of transferase activity GO:0051347 167 0.101
cell type specific apoptotic process GO:0097285 268 0.100
positive regulation of defense response GO:0031349 124 0.100
multicellular organismal signaling GO:0035637 91 0.100
sensory perception of pain GO:0019233 47 0.099
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.098
ribonucleotide metabolic process GO:0009259 291 0.098
Mouse
cation homeostasis GO:0055080 212 0.097
lymphocyte migration GO:0072676 26 0.097
muscle system process GO:0003012 141 0.096
cell adhesion GO:0007155 329 0.096
Mouse
axonogenesis GO:0007409 274 0.095
b cell differentiation GO:0030183 78 0.095
negative t cell selection GO:0043383 13 0.095
regulation of protein transport GO:0051223 163 0.094
striated muscle contraction GO:0006941 45 0.094
peptide transport GO:0015833 133 0.094
Mouse
mesenchymal cell development GO:0014031 93 0.094
regulation of multi organism process GO:0043900 111 0.093
myeloid dendritic cell activation GO:0001773 25 0.093
heart process GO:0003015 94 0.093
ear development GO:0043583 200 0.091
negative regulation of ovulation GO:0060280 1 0.091
sequestering of calcium ion GO:0051208 18 0.090
metal ion homeostasis GO:0055065 189 0.089
positive regulation of angiogenesis GO:0045766 46 0.088
glial cell differentiation GO:0010001 131 0.088
commissural neuron axon guidance GO:0071679 8 0.088
negative regulation of angiogenesis GO:0016525 25 0.087
regulation of epithelial cell proliferation GO:0050678 141 0.087
Mouse
positive regulation of muscle cell differentiation GO:0051149 39 0.086
Mouse
epithelial cell proliferation GO:0050673 174 0.086
Mouse
b cell activation GO:0042113 161 0.085
regulation of homeostatic process GO:0032844 182 0.085
Mouse
placenta development GO:0001890 140 0.085
regulation of leukocyte proliferation GO:0070663 121 0.084
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.084
fasciculation of motor neuron axon GO:0097156 2 0.084
ascending aorta morphogenesis GO:0035910 3 0.084
sensory organ morphogenesis GO:0090596 242 0.083
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.082
t cell extravasation GO:0072683 4 0.082
ventricular septum development GO:0003281 42 0.081
ribonucleoside triphosphate metabolic process GO:0009199 220 0.081
Mouse
homeostasis of number of cells GO:0048872 210 0.080
muscle cell development GO:0055001 133 0.079
cardiac chamber morphogenesis GO:0003206 93 0.079
positive regulation of monocyte chemotaxis GO:0090026 2 0.079
regulation of protein complex assembly GO:0043254 83 0.078
regulation of cytokine production GO:0001817 266 0.078
positive regulation of cytokine production GO:0001819 174 0.078
regulation of anatomical structure size GO:0090066 178 0.078
mesenchyme development GO:0060485 152 0.078
organic hydroxy compound metabolic process GO:1901615 203 0.077
dendrite extension GO:0097484 3 0.077
purine nucleotide metabolic process GO:0006163 302 0.077
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.077
ear morphogenesis GO:0042471 118 0.076
cytokine mediated signaling pathway GO:0019221 115 0.076
amide transport GO:0042886 138 0.076
Mouse
cation transport GO:0006812 399 0.075
cellular ion homeostasis GO:0006873 165 0.074
purine containing compound metabolic process GO:0072521 311 0.074
Mouse
stem cell differentiation GO:0048863 268 0.073
prevention of polyspermy GO:0060468 4 0.073
canonical wnt signaling pathway GO:0060070 130 0.073
cytosolic calcium ion homeostasis GO:0051480 70 0.073
positive regulation of immune effector process GO:0002699 107 0.073
tricuspid valve formation GO:0003195 2 0.072
purine ribonucleotide metabolic process GO:0009150 290 0.072
Mouse
muscle tissue development GO:0060537 308 0.071
Mouse
cognition GO:0050890 149 0.071
glucose homeostasis GO:0042593 128 0.071
Mouse
neuron migration GO:0001764 122 0.070
cell migration involved in gastrulation GO:0042074 13 0.069
germ cell development GO:0007281 185 0.069
regulation of monocyte chemotaxis GO:0090025 3 0.069
regulation of endothelial cell migration GO:0010594 22 0.069
muscle contraction GO:0006936 101 0.068
regulation of innate immune response GO:0045088 91 0.068
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.068
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.067
response to molecule of bacterial origin GO:0002237 143 0.067
interleukin 12 secretion GO:0072610 3 0.067
cellular response to carbohydrate stimulus GO:0071322 50 0.067
Mouse
negative regulation of neuron projection regeneration GO:0070571 3 0.067
cell substrate adhesion GO:0031589 130 0.067
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.066
nephron development GO:0072006 109 0.066
regulation of cell projection organization GO:0031344 206 0.066
eosinophil migration GO:0072677 3 0.066
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.066
regulation of muscle tissue development GO:1901861 97 0.066
Mouse
protein localization to nucleus GO:0034504 121 0.066
regulation of ovulation GO:0060278 3 0.065
skin development GO:0043588 220 0.065
Worm
positive regulation of behavior GO:0048520 40 0.065
leukocyte mediated immunity GO:0002443 174 0.065
atrial septum primum morphogenesis GO:0003289 3 0.065
regulation of secretion by cell GO:1903530 249 0.065
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.065
parathyroid hormone secretion GO:0035898 2 0.064
ribonucleoside triphosphate catabolic process GO:0009203 199 0.063
Mouse
substrate dependent cell migration GO:0006929 18 0.063
rac protein signal transduction GO:0016601 13 0.063
adult locomotory behavior GO:0008344 91 0.063
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.063
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.063
cell adhesion mediated by integrin GO:0033627 18 0.063
regulation of dendritic spine development GO:0060998 22 0.062
nephron tubule development GO:0072080 84 0.062
regulation of cytoplasmic transport GO:1903649 112 0.062
developmental maturation GO:0021700 193 0.062
response to oxygen levels GO:0070482 62 0.062
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.062
notochord development GO:0030903 20 0.061
positive regulation of acute inflammatory response GO:0002675 16 0.061
extracellular matrix dependent thymocyte migration GO:0072680 1 0.060
response to acid chemical GO:0001101 111 0.060
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.060
endothelial cell migration GO:0043542 44 0.060
leukocyte proliferation GO:0070661 172 0.060
Mouse
endodermal cell fate specification GO:0001714 4 0.060
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.060
positive regulation of programmed cell death GO:0043068 218 0.060
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.060
regulation of stem cell proliferation GO:0072091 78 0.060
tube formation GO:0035148 140 0.060
purine nucleoside catabolic process GO:0006152 205 0.059
Mouse
positive thymic t cell selection GO:0045059 13 0.059
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.058
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.058
regulation of heart contraction GO:0008016 77 0.058
regulation of cell adhesion GO:0030155 154 0.058
Mouse
mesenchymal cell differentiation GO:0048762 107 0.058
regulation of eosinophil migration GO:2000416 2 0.058
leukocyte chemotaxis GO:0030595 69 0.058
glycosyl compound metabolic process GO:1901657 246 0.058
Mouse
cardiac muscle contraction GO:0060048 32 0.058
regulation of intracellular transport GO:0032386 159 0.057
regulation of epithelial to mesenchymal transition GO:0010717 22 0.057
release of sequestered calcium ion into cytosol GO:0051209 42 0.057
apoptotic signaling pathway GO:0097190 306 0.057
sprouting angiogenesis GO:0002040 26 0.057
single organism cell adhesion GO:0098602 156 0.057
Mouse
digestive tract morphogenesis GO:0048546 147 0.056
regulation of kinase activity GO:0043549 249 0.056
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
Mouse
positive regulation of apoptotic process GO:0043065 217 0.056
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.056
gland development GO:0048732 330 0.055
humoral immune response GO:0006959 57 0.054
single organism nuclear import GO:1902593 95 0.054
regulation of defense response GO:0031347 233 0.054
activation of mapk activity GO:0000187 59 0.054
regulation of positive chemotaxis GO:0050926 7 0.053
regulation of vesicle mediated transport GO:0060627 139 0.053
pulmonary valve development GO:0003177 5 0.053
heart trabecula formation GO:0060347 14 0.053
digestive tract development GO:0048565 190 0.053
positive regulation of cell migration GO:0030335 109 0.053
activation of ras gtpase activity GO:0032856 11 0.052
calcium ion transport into cytosol GO:0060402 48 0.052
maintenance of location GO:0051235 89 0.052
cochlea development GO:0090102 35 0.052
regulation of cellular component size GO:0032535 121 0.052
positive regulation of t cell proliferation GO:0042102 52 0.052
Mouse
asymmetric neuroblast division GO:0055059 1 0.052
fibronectin dependent thymocyte migration GO:0072681 1 0.051
ventricular septum morphogenesis GO:0060412 27 0.051
sensory organ boundary specification GO:0008052 1 0.051
regulation of t cell costimulation GO:2000523 2 0.051
regulation of blood circulation GO:1903522 93 0.050
negative regulation of phosphorylation GO:0042326 166 0.050
palate development GO:0060021 76 0.050
morphogenesis of a branching epithelium GO:0061138 193 0.050
myelination in peripheral nervous system GO:0022011 19 0.050
positive regulation of t cell extravasation GO:2000409 2 0.049
positive regulation of monocyte extravasation GO:2000439 1 0.049
regulation of immunological synapse formation GO:2000520 2 0.049
transmission of nerve impulse GO:0019226 76 0.049
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.049
kidney morphogenesis GO:0060993 83 0.049
regulation of cytokine biosynthetic process GO:0042035 59 0.049
negative regulation of apoptotic signaling pathway GO:2001234 104 0.049
labyrinthine layer blood vessel development GO:0060716 21 0.048
formation of organ boundary GO:0010160 1 0.048
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.048
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.048
Mouse
eosinophil activation involved in immune response GO:0002278 1 0.048
negative regulation of immune system process GO:0002683 209 0.048
regulation of cell cycle GO:0051726 281 0.048
positive regulation of cell adhesion GO:0045785 80 0.048
dendritic spine development GO:0060996 30 0.048
cellular component assembly involved in morphogenesis GO:0010927 139 0.048
production of molecular mediator of immune response GO:0002440 103 0.048
myeloid cell apoptotic process GO:0033028 22 0.047
positive regulation of t cell costimulation GO:2000525 2 0.047
fertilization GO:0009566 127 0.047
retinal blood vessel morphogenesis GO:0061304 3 0.047
regulation of striated muscle cell differentiation GO:0051153 81 0.047
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.046
epithelium migration GO:0090132 63 0.046
aromatic compound catabolic process GO:0019439 286 0.046
Mouse
positive regulation of kinase activity GO:0033674 155 0.046
cellular glucose homeostasis GO:0001678 52 0.046
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.046
Mouse
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.046
nuclear transport GO:0051169 139 0.046
membrane raft organization GO:0031579 5 0.046
macrophage activation GO:0042116 27 0.046
regulation of inflammatory response GO:0050727 147 0.045
actin filament based movement GO:0030048 23 0.045
t cell migration GO:0072678 19 0.045
regulation of apoptotic signaling pathway GO:2001233 197 0.045
positive regulation of intracellular transport GO:0032388 70 0.045
regulation of protein import into nucleus GO:0042306 52 0.045
neuronal action potential GO:0019228 54 0.044
regulation of dendritic cell chemotaxis GO:2000508 1 0.044
cell fate commitment GO:0045165 210 0.044
leukocyte apoptotic process GO:0071887 71 0.044
neuroblast proliferation GO:0007405 49 0.044
neural tube development GO:0021915 160 0.044
regulation of dendritic spine morphogenesis GO:0061001 17 0.044
positive regulation of cell motility GO:2000147 116 0.044
purine nucleoside triphosphate catabolic process GO:0009146 203 0.044
Mouse
embryonic epithelial tube formation GO:0001838 130 0.044
regulation of metal ion transport GO:0010959 106 0.044
cellular response to lipopolysaccharide GO:0071222 77 0.043
embryonic placenta development GO:0001892 98 0.043
myelination GO:0042552 74 0.043
endocytosis GO:0006897 168 0.043
microglial cell activation GO:0001774 3 0.043
endocardial cushion development GO:0003197 26 0.043
purine ribonucleoside metabolic process GO:0046128 241 0.042
Mouse
cellular metal ion homeostasis GO:0006875 151 0.042
nephron epithelium morphogenesis GO:0072088 68 0.042
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.042
negative regulation of macrophage apoptotic process GO:2000110 3 0.042
sensory perception GO:0007600 245 0.042
pulmonary valve morphogenesis GO:0003184 5 0.042
cell migration to the midline involved in heart development GO:0003318 1 0.042
cellular response to biotic stimulus GO:0071216 92 0.042
insulin secretion GO:0030073 89 0.041
Mouse
regulation of auditory receptor cell differentiation GO:0045607 4 0.041
mesonephric tubule development GO:0072164 94 0.041
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.041
Mouse
peptide hormone secretion GO:0030072 109 0.041
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.041
positive regulation of organelle organization GO:0010638 128 0.041
endocrine process GO:0050886 39 0.040
regionalization GO:0003002 337 0.040
regulation of ion transport GO:0043269 215 0.040
regulation of map kinase activity GO:0043405 120 0.040
macromolecule catabolic process GO:0009057 281 0.040
regulation of endothelial cell proliferation GO:0001936 23 0.040
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.040
protein kinase b signaling GO:0043491 74 0.040
lateral line system development GO:0048925 1 0.040
positive regulation of inflammatory response GO:0050729 47 0.040
negative regulation of immune effector process GO:0002698 55 0.040
nitrogen compound transport GO:0071705 271 0.040
Mouse
endothelial cell proliferation GO:0001935 27 0.040
dendritic spine morphogenesis GO:0060997 22 0.040

Efna1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
heart disease DOID:114 0 0.340
disease of anatomical entity DOID:7 0 0.340
cardiovascular system disease DOID:1287 0 0.340
muscular disease DOID:0080000 0 0.045
musculoskeletal system disease DOID:17 0 0.045