Mus musculus

0 known processes

Klk11

kallikrein related-peptidase 11

(Aliases: Prss20,MGC144345,2310015I08Rik,TLSP)

Klk11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.242
epidermis development GO:0008544 187 0.203
protein processing GO:0016485 163 0.155
Mouse
skin development GO:0043588 220 0.114
urogenital system development GO:0001655 261 0.111
regulation of kinase activity GO:0043549 249 0.100
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.097
inorganic ion transmembrane transport GO:0098660 234 0.083
negative regulation of molecular function GO:0044092 258 0.078
regulation of hormone levels GO:0010817 211 0.070
negative regulation of protein metabolic process GO:0051248 282 0.067
spermatogenesis GO:0007283 284 0.062
fertilization GO:0009566 127 0.062
Mouse
macromolecule catabolic process GO:0009057 281 0.057
Mouse
hair follicle development GO:0001942 85 0.057
molting cycle GO:0042303 90 0.055
cell type specific apoptotic process GO:0097285 268 0.052
protein maturation GO:0051604 176 0.051
Mouse
regulation of neuron differentiation GO:0045664 281 0.051
hair cycle GO:0042633 90 0.049
multicellular organismal homeostasis GO:0048871 164 0.048
epithelial cell proliferation GO:0050673 174 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.046
organic acid biosynthetic process GO:0016053 86 0.044
epithelial cell development GO:0002064 159 0.043
inorganic cation transmembrane transport GO:0098662 207 0.042
skin morphogenesis GO:0043589 38 0.042
lymphocyte differentiation GO:0030098 242 0.041
regulation of lipid metabolic process GO:0019216 118 0.041
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.041
b cell activation GO:0042113 161 0.041
hair follicle morphogenesis GO:0031069 29 0.040
sensory organ morphogenesis GO:0090596 242 0.040
regulation of protein maturation GO:1903317 96 0.040
negative regulation of protein maturation GO:1903318 79 0.039
negative regulation of protein processing GO:0010955 79 0.039
embryonic placenta development GO:0001892 98 0.039
regulation of protein localization GO:0032880 231 0.039
kidney development GO:0001822 213 0.038
regulation of protein processing GO:0070613 96 0.038
renal system development GO:0072001 225 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
epithelial tube morphogenesis GO:0060562 303 0.037
cation transmembrane transport GO:0098655 266 0.037
regulation of anatomical structure size GO:0090066 178 0.037
Mouse
primary neural tube formation GO:0014020 95 0.036
regulation of epidermal cell differentiation GO:0045604 21 0.036
regulation of peptidase activity GO:0052547 96 0.035
extracellular structure organization GO:0043062 148 0.035
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.035
regulation of secretion GO:0051046 274 0.034
protein ubiquitination GO:0016567 171 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
cellular ketone metabolic process GO:0042180 84 0.033
developmental maturation GO:0021700 193 0.033
positive regulation of neuron differentiation GO:0045666 141 0.033
mapk cascade GO:0000165 281 0.032
skeletal system development GO:0001501 356 0.032
single fertilization GO:0007338 82 0.032
Mouse
regulation of response to wounding GO:1903034 189 0.031
cation transport GO:0006812 399 0.031
negative regulation of proteolysis GO:0045861 74 0.031
wnt signaling pathway GO:0016055 188 0.030
phospholipid metabolic process GO:0006644 87 0.030
Mouse
neural tube development GO:0021915 160 0.030
metanephric loop of henle development GO:0072236 4 0.030
cardiac chamber development GO:0003205 108 0.029
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.029
Mouse
carbohydrate metabolic process GO:0005975 230 0.029
negative regulation of peptidase activity GO:0010466 46 0.029
cation homeostasis GO:0055080 212 0.028
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
protein catabolic process GO:0030163 221 0.028
Mouse
regulation of establishment of protein localization GO:0070201 181 0.028
morphogenesis of a polarized epithelium GO:0001738 37 0.027
tube closure GO:0060606 91 0.027
regulation of cell activation GO:0050865 289 0.027
positive regulation of epithelial cell proliferation GO:0050679 68 0.027
dna metabolic process GO:0006259 303 0.026
regulation of cell projection organization GO:0031344 206 0.026
regulation of epidermis development GO:0045682 33 0.026
t cell differentiation GO:0030217 174 0.025
positive regulation of transferase activity GO:0051347 167 0.025
Mouse
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.025
regulation of defense response GO:0031347 233 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.024
oxidation reduction process GO:0055114 342 0.023
translation GO:0006412 93 0.023
ear development GO:0043583 200 0.023
positive regulation of cell death GO:0010942 224 0.023
amine metabolic process GO:0009308 45 0.023
negative regulation of transferase activity GO:0051348 85 0.023
camera type eye development GO:0043010 266 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.023
Mouse
cardiac ventricle development GO:0003231 83 0.023
Mouse
positive regulation of cell development GO:0010720 237 0.023
wound healing GO:0042060 157 0.023
cell maturation GO:0048469 127 0.023
negative regulation of endopeptidase activity GO:0010951 44 0.022
cellular lipid metabolic process GO:0044255 323 0.022
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.022
muscle tissue morphogenesis GO:0060415 53 0.022
Mouse
hormone metabolic process GO:0042445 86 0.022
cellular response to cytokine stimulus GO:0071345 189 0.022
nuclear division GO:0000280 158 0.022
negative regulation of protein modification process GO:0031400 163 0.022
negative regulation of hydrolase activity GO:0051346 71 0.022
regulation of endopeptidase activity GO:0052548 89 0.021
regulation of systemic arterial blood pressure GO:0003073 61 0.021
Mouse
chromatin modification GO:0016568 187 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
keratinocyte differentiation GO:0030216 48 0.021
regulation of hydrolase activity GO:0051336 246 0.021
anatomical structure homeostasis GO:0060249 145 0.021
regulation of epithelial cell proliferation GO:0050678 141 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
cellular modified amino acid metabolic process GO:0006575 63 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
interleukin 8 production GO:0032637 4 0.021
paraxial mesodermal cell differentiation GO:0048342 2 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
odontogenesis of dentin containing tooth GO:0042475 66 0.020
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.020
production of molecular mediator of immune response GO:0002440 103 0.020
germ cell development GO:0007281 185 0.020
epithelial tube formation GO:0072175 130 0.020
establishment of tissue polarity GO:0007164 28 0.020
regulation of blood vessel size GO:0050880 56 0.020
Mouse
inflammatory response GO:0006954 244 0.020
Mouse
regulation of thyroid hormone generation GO:2000609 4 0.020
microtubule based process GO:0007017 236 0.019
organelle fission GO:0048285 170 0.019
extracellular matrix organization GO:0030198 147 0.019
Mouse
vascular process in circulatory system GO:0003018 62 0.019
Mouse
cellular amine metabolic process GO:0044106 44 0.019
negative regulation of cell development GO:0010721 169 0.019
regulation of organelle organization GO:0033043 289 0.019
cell recognition GO:0008037 83 0.019
Mouse
regulation of cell motility GO:2000145 236 0.019
intermediate filament based process GO:0045103 27 0.019
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.019
t cell activation GO:0042110 289 0.018
cell activation involved in immune response GO:0002263 126 0.018
negative regulation of hormone biosynthetic process GO:0032353 4 0.018
regulation of mapk cascade GO:0043408 248 0.018
chromatin organization GO:0006325 206 0.018
blastocyst development GO:0001824 80 0.018
kidney epithelium development GO:0072073 121 0.018
placenta development GO:0001890 140 0.018
lipid biosynthetic process GO:0008610 179 0.017
tube formation GO:0035148 140 0.017
positive regulation of nervous system development GO:0051962 221 0.017
maintenance of location GO:0051235 89 0.017
muscle tissue development GO:0060537 308 0.017
Mouse
intermediate filament bundle assembly GO:0045110 3 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
paraxial mesodermal cell fate commitment GO:0048343 2 0.017
rhythmic process GO:0048511 174 0.017
regionalization GO:0003002 337 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
nucleotide metabolic process GO:0009117 332 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
cellular carbohydrate metabolic process GO:0044262 119 0.017
blood circulation GO:0008015 195 0.017
Mouse
action potential GO:0001508 78 0.017
negative regulation of kinase activity GO:0033673 81 0.017
regulation of transferase activity GO:0051338 263 0.017
Mouse
positive regulation of interleukin 8 production GO:0032757 2 0.016
renal inner medulla development GO:0072053 3 0.016
oxygen homeostasis GO:0032364 2 0.016
neural tube formation GO:0001841 108 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
oogenesis GO:0048477 56 0.016
hindbrain development GO:0030902 128 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
regulation of cell cycle process GO:0010564 160 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
mitotic cell cycle process GO:1903047 159 0.016
somatotropin secreting cell differentiation GO:0060126 4 0.016
small gtpase mediated signal transduction GO:0007264 97 0.015
Mouse
peptidyl amino acid modification GO:0018193 336 0.015
positive regulation of kinase activity GO:0033674 155 0.015
Mouse
inner ear morphogenesis GO:0042472 101 0.015
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.015
Mouse
negative regulation of nervous system development GO:0051961 156 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
regulation of cell cycle GO:0051726 281 0.015
organ growth GO:0035265 117 0.015
cochlea development GO:0090102 35 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
respiratory system development GO:0060541 190 0.015
transmembrane transport GO:0055085 412 0.014
small molecule biosynthetic process GO:0044283 132 0.014
stem cell development GO:0048864 219 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
intracellular receptor signaling pathway GO:0030522 74 0.014
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.014
female gamete generation GO:0007292 74 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
regulation of mitotic cell cycle GO:0007346 126 0.014
regulation of proteolysis GO:0030162 164 0.014
ras protein signal transduction GO:0007265 77 0.014
female sex differentiation GO:0046660 84 0.014
alcohol metabolic process GO:0006066 116 0.014
potassium ion transport GO:0006813 52 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
female gonad development GO:0008585 71 0.014
cytokine production GO:0001816 319 0.014
paramesonephric duct development GO:0061205 3 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.014
Mouse
cell adhesion GO:0007155 329 0.014
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
striated muscle tissue development GO:0014706 293 0.014
Mouse
negative regulation of neuron death GO:1901215 98 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
renal tubule development GO:0061326 87 0.014
neural tube closure GO:0001843 90 0.013
cell differentiation involved in embryonic placenta development GO:0060706 26 0.013
respiratory tube development GO:0030323 167 0.013
cardiac muscle tissue development GO:0048738 130 0.013
Mouse
heterocycle catabolic process GO:0046700 280 0.013
rho protein signal transduction GO:0007266 32 0.013
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.013
purine nucleoside metabolic process GO:0042278 241 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
developmental cell growth GO:0048588 84 0.013
ureteric bud development GO:0001657 94 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
metanephros development GO:0001656 79 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
regulation of translation GO:0006417 71 0.013
positive regulation of anagen GO:0051885 1 0.013
response to oxygen levels GO:0070482 62 0.013
mesenchymal cell differentiation GO:0048762 107 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
myoblast differentiation GO:0045445 52 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
mesonephros development GO:0001823 97 0.013
establishment of skin barrier GO:0061436 14 0.013
leukocyte differentiation GO:0002521 342 0.013
hydrogen ion transmembrane transport GO:1902600 25 0.013
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.013
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.013
positive regulation of protein modification process GO:0031401 299 0.013
peptidyl serine modification GO:0018209 83 0.013
regulation of metal ion transport GO:0010959 106 0.013
positive regulation of organelle organization GO:0010638 128 0.013
establishment of planar polarity GO:0001736 28 0.013
oviduct development GO:0060066 3 0.013
regulation of kidney development GO:0090183 40 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
ion transmembrane transport GO:0034220 361 0.012
mesenchyme development GO:0060485 152 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
oocyte construction GO:0007308 2 0.012
nucleobase containing small molecule metabolic process GO:0055086 352 0.012
cellular protein catabolic process GO:0044257 155 0.012
purine containing compound metabolic process GO:0072521 311 0.012
tendon cell differentiation GO:0035990 4 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.012
regulation of interleukin 8 secretion GO:2000482 2 0.012
regulation of neuron death GO:1901214 134 0.012
negative regulation of hormone metabolic process GO:0032351 4 0.012
sulfur compound metabolic process GO:0006790 100 0.012
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.012
maintenance of cell number GO:0098727 3 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
regulation of intracellular transport GO:0032386 159 0.012
regulation of protein catabolic process GO:0042176 108 0.012
detection of stimulus GO:0051606 84 0.012
tissue homeostasis GO:0001894 115 0.012
mitotic cell cycle GO:0000278 195 0.012
negative regulation of response to wounding GO:1903035 77 0.012
nephron epithelium development GO:0072009 92 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
muscle cell development GO:0055001 133 0.012
tissue regeneration GO:0042246 22 0.012
regulation of cellular response to stress GO:0080135 159 0.012
negative regulation of epithelial cell proliferation GO:0050680 64 0.012
microtubule cytoskeleton organization GO:0000226 157 0.011
mesonephric duct morphogenesis GO:0072180 4 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
regulation of reproductive process GO:2000241 66 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
regulation of auditory receptor cell differentiation GO:0045607 4 0.011
regulation of nuclear division GO:0051783 56 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regeneration GO:0031099 38 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
regulation of transforming growth factor beta2 production GO:0032909 2 0.011
regulation of cytokine production GO:0001817 266 0.011
aromatic compound catabolic process GO:0019439 286 0.011
glycoprotein metabolic process GO:0009100 116 0.011
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.011
mesonephric epithelium development GO:0072163 94 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
fatty acid metabolic process GO:0006631 121 0.011
appendage development GO:0048736 166 0.011
exocytosis GO:0006887 121 0.011
muscle fiber development GO:0048747 76 0.011
regulation of ion transport GO:0043269 215 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
cellular homeostasis GO:0019725 240 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
nephron development GO:0072006 109 0.011
foregut regionalization GO:0060423 3 0.011
steroid metabolic process GO:0008202 119 0.011
keratinocyte proliferation GO:0043616 21 0.011
cellular potassium ion transport GO:0071804 43 0.011
apoptotic signaling pathway GO:0097190 306 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.011
nephron epithelium morphogenesis GO:0072088 68 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
nucleoside catabolic process GO:0009164 206 0.011
positive regulation of lipid metabolic process GO:0045834 40 0.011
Mouse
kidney rudiment formation GO:0072003 3 0.011
regulation of neuron projection development GO:0010975 169 0.011
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.011
mesangial cell differentiation GO:0072007 4 0.011
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.011
epidermis morphogenesis GO:0048730 33 0.011
regulation of cytoplasmic transport GO:1903649 112 0.010
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
negative regulation of lipid metabolic process GO:0045833 30 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
cellular chemical homeostasis GO:0055082 215 0.010
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.010
dephosphorylation GO:0016311 129 0.010
cell cell junction organization GO:0045216 72 0.010
mesonephric tubule development GO:0072164 94 0.010
negative regulation of wnt signaling pathway GO:0030178 73 0.010
purine nucleotide metabolic process GO:0006163 302 0.010
regulation of system process GO:0044057 200 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.010
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.010
negative regulation of inflammatory response GO:0050728 61 0.010
fatty acid biosynthetic process GO:0006633 41 0.010
heart process GO:0003015 94 0.010
Mouse
muscle cell differentiation GO:0042692 261 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
oocyte axis specification GO:0007309 2 0.010
aminoglycan metabolic process GO:0006022 34 0.010

Klk11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
retinal disease DOID:5679 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011