Mus musculus

0 known processes

Pmpcb

peptidase (mitochondrial processing) beta

(Aliases: MPPB,MPPP52,MPP11,3110004O18Rik)

Pmpcb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 134 0.602
Yeast
oxidation reduction process GO:0055114 342 0.371
monocarboxylic acid metabolic process GO:0032787 191 0.304
purine ribonucleoside metabolic process GO:0046128 241 0.285
ribonucleoside monophosphate metabolic process GO:0009161 80 0.205
apoptotic signaling pathway GO:0097190 306 0.193
cellular respiration GO:0045333 38 0.183
generation of precursor metabolites and energy GO:0006091 103 0.177
ribonucleoside triphosphate metabolic process GO:0009199 220 0.157
purine ribonucleotide metabolic process GO:0009150 290 0.152
regulation of cellular catabolic process GO:0031329 242 0.147
mitochondrial electron transport nadh to ubiquinone GO:0006120 4 0.139
energy derivation by oxidation of organic compounds GO:0015980 77 0.128
neuron apoptotic process GO:0051402 142 0.123
atp metabolic process GO:0046034 75 0.107
nucleobase containing small molecule metabolic process GO:0055086 352 0.107
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.097
nucleoside monophosphate metabolic process GO:0009123 85 0.096
regulation of proteolysis GO:0030162 164 0.096
ribose phosphate metabolic process GO:0019693 291 0.095
intrinsic apoptotic signaling pathway GO:0097193 132 0.095
male gamete generation GO:0048232 285 0.090
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.087
regulation of apoptotic signaling pathway GO:2001233 197 0.086
cellular hyperosmotic salinity response GO:0071475 0 0.081
glycosyl compound metabolic process GO:1901657 246 0.075
cell type specific apoptotic process GO:0097285 268 0.070
negative regulation of protein metabolic process GO:0051248 282 0.069
regulation of cysteine type endopeptidase activity GO:2000116 65 0.066
protein maturation GO:0051604 176 0.063
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.062
cellular ketone metabolic process GO:0042180 84 0.061
transmembrane transport GO:0055085 412 0.058
positive regulation of proteolysis GO:0045862 85 0.058
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.054
mitochondrial transport GO:0006839 36 0.053
Yeast
cellular macromolecule catabolic process GO:0044265 206 0.052
purine nucleotide metabolic process GO:0006163 302 0.052
ribonucleoside metabolic process GO:0009119 245 0.051
cellular amino acid metabolic process GO:0006520 103 0.051
nucleotide metabolic process GO:0009117 332 0.051
innate immune response GO:0045087 157 0.050
coenzyme metabolic process GO:0006732 52 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
spermatogenesis GO:0007283 284 0.048
purine nucleoside monophosphate metabolic process GO:0009126 81 0.046
trna metabolic process GO:0006399 11 0.045
spermatid differentiation GO:0048515 115 0.041
negative regulation of neuron apoptotic process GO:0043524 92 0.040
fatty acid beta oxidation GO:0006635 16 0.040
small molecule biosynthetic process GO:0044283 132 0.040
nucleoside phosphate metabolic process GO:0006753 338 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.038
regulation of endopeptidase activity GO:0052548 89 0.038
positive regulation of cell death GO:0010942 224 0.038
regulation of cell cycle GO:0051726 281 0.037
homeostasis of number of cells GO:0048872 210 0.037
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.036
negative regulation of apoptotic signaling pathway GO:2001234 104 0.035
cellularization GO:0007349 1 0.035
protein processing GO:0016485 163 0.035
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.035
sulfur compound metabolic process GO:0006790 100 0.035
nitrogen compound transport GO:0071705 271 0.033
protein localization to mitochondrion GO:0070585 15 0.033
Yeast
regulation of membrane potential GO:0042391 192 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
nucleoside metabolic process GO:0009116 246 0.032
cellular nitrogen compound catabolic process GO:0044270 280 0.031
protein targeting GO:0006605 143 0.031
Yeast
positive regulation of hydrolase activity GO:0051345 148 0.031
regulation of secretion by cell GO:1903530 249 0.030
acyl coa metabolic process GO:0006637 19 0.030
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.030
gland development GO:0048732 330 0.030
purine containing compound metabolic process GO:0072521 311 0.030
spermatid development GO:0007286 108 0.030
regulation of hydrolase activity GO:0051336 246 0.029
thioester metabolic process GO:0035383 19 0.028
small molecule catabolic process GO:0044282 71 0.028
macromolecule catabolic process GO:0009057 281 0.028
purine nucleoside metabolic process GO:0042278 241 0.027
response to oxidative stress GO:0006979 123 0.027
sulfur compound biosynthetic process GO:0044272 37 0.027
regulation of organelle organization GO:0033043 289 0.027
purine nucleotide catabolic process GO:0006195 211 0.026
protein localization to organelle GO:0033365 185 0.026
Yeast
ribonucleotide metabolic process GO:0009259 291 0.026
intracellular protein transport GO:0006886 204 0.026
Yeast
modification dependent macromolecule catabolic process GO:0043632 133 0.025
germ cell development GO:0007281 185 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
atp synthesis coupled electron transport GO:0042773 8 0.025
locomotory behavior GO:0007626 195 0.025
cellular lipid metabolic process GO:0044255 323 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
oxidative phosphorylation GO:0006119 14 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
sperm individualization GO:0007291 1 0.023
response to inorganic substance GO:0010035 96 0.023
lipid oxidation GO:0034440 29 0.023
regulation of peptidase activity GO:0052547 96 0.022
inflammatory response GO:0006954 244 0.022
cellular protein complex assembly GO:0043623 116 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
negative regulation of cell development GO:0010721 169 0.021
acetyl coa biosynthetic process GO:0006085 5 0.021
regulation of protein maturation GO:1903317 96 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
fatty acid metabolic process GO:0006631 121 0.020
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.020
negative regulation of protein processing GO:0010955 79 0.020
neuron death GO:0070997 154 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.019
amine metabolic process GO:0009308 45 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
organophosphate catabolic process GO:0046434 232 0.019
nicotinamide nucleotide metabolic process GO:0046496 12 0.019
striated muscle tissue development GO:0014706 293 0.019
organic acid biosynthetic process GO:0016053 86 0.018
organic acid catabolic process GO:0016054 51 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
regulation of neuron death GO:1901214 134 0.018
regulation of neuron apoptotic process GO:0043523 122 0.018
apoptotic mitochondrial changes GO:0008637 48 0.018
t cell proliferation GO:0042098 120 0.018
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
myeloid cell differentiation GO:0030099 233 0.018
glycerophospholipid metabolic process GO:0006650 71 0.017
exocytosis GO:0006887 121 0.017
regulation of secretion GO:0051046 274 0.017
heterocycle catabolic process GO:0046700 280 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
regulation of protein complex assembly GO:0043254 83 0.017
protein catabolic process GO:0030163 221 0.016
mitochondrial atp synthesis coupled electron transport GO:0042775 8 0.016
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
response to oxygen levels GO:0070482 62 0.016
regulation of cell cycle process GO:0010564 160 0.016
peptide transport GO:0015833 133 0.015
positive regulation of peptidase activity GO:0010952 49 0.015
digestive tract morphogenesis GO:0048546 147 0.015
lipid biosynthetic process GO:0008610 179 0.015
tube formation GO:0035148 140 0.015
regulation of cellular response to stress GO:0080135 159 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
positive regulation of protein modification process GO:0031401 299 0.015
dephosphorylation GO:0016311 129 0.015
ion transmembrane transport GO:0034220 361 0.014
neuron migration GO:0001764 122 0.014
aromatic compound catabolic process GO:0019439 286 0.014
protein oligomerization GO:0051259 67 0.014
hepaticobiliary system development GO:0061008 67 0.014
protein oxidation GO:0018158 2 0.014
protein import GO:0017038 101 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
regulation of execution phase of apoptosis GO:1900117 9 0.014
regulation of hormone levels GO:0010817 211 0.014
leukocyte proliferation GO:0070661 172 0.014
acyl coa biosynthetic process GO:0071616 7 0.014
regulation of peptide transport GO:0090087 91 0.014
protein homooligomerization GO:0051260 43 0.014
phagocytosis GO:0006909 66 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
forebrain cell migration GO:0021885 58 0.013
liver development GO:0001889 66 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
regulation of cellular amine metabolic process GO:0033238 20 0.013
response to lipopolysaccharide GO:0032496 128 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
Yeast
response to organonitrogen compound GO:0010243 246 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
regulation of protein processing GO:0070613 96 0.013
cell maturation GO:0048469 127 0.013
regulation of cell activation GO:0050865 289 0.013
epithelial cell proliferation GO:0050673 174 0.012
dna metabolic process GO:0006259 303 0.012
zymogen activation GO:0031638 41 0.012
metal ion homeostasis GO:0055065 189 0.012
regulation of response to wounding GO:1903034 189 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
t cell activation GO:0042110 289 0.012
nuclear transport GO:0051169 139 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
lymphocyte proliferation GO:0046651 164 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
leukocyte mediated immunity GO:0002443 174 0.012
cellular response to oxygen radical GO:0071450 14 0.012
immune effector process GO:0002252 321 0.012
positive regulation of endopeptidase activity GO:0010950 43 0.012
wound healing GO:0042060 157 0.012
forebrain development GO:0030900 302 0.012
negative regulation of transferase activity GO:0051348 85 0.012
postsynaptic membrane organization GO:0001941 18 0.011
oxygen homeostasis GO:0032364 2 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
protein folding GO:0006457 28 0.011
cofactor metabolic process GO:0051186 80 0.011
amide transport GO:0042886 138 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
regulation of tube size GO:0035150 57 0.011
chromatin modification GO:0016568 187 0.011
negative regulation of molecular function GO:0044092 258 0.011
superoxide metabolic process GO:0006801 27 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
nucleotide catabolic process GO:0009166 217 0.011
extracellular matrix organization GO:0030198 147 0.011
gtp catabolic process GO:0006184 143 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
protein import into peroxisome matrix GO:0016558 3 0.011
negative regulation of protein modification process GO:0031400 163 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.010
protein transmembrane transport GO:0071806 8 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.010
regulation of intracellular transport GO:0032386 159 0.010
purine containing compound catabolic process GO:0072523 213 0.010
coenzyme biosynthetic process GO:0009108 23 0.010
positive regulation of growth GO:0045927 104 0.010
phospholipid metabolic process GO:0006644 87 0.010
cytoplasmic transport GO:0016482 234 0.010
Yeast
maintenance of location GO:0051235 89 0.010
fatty acid biosynthetic process GO:0006633 41 0.010
positive regulation of organelle organization GO:0010638 128 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
regulation of chromosome organization GO:0033044 83 0.010
positive regulation of programmed cell death GO:0043068 218 0.010

Pmpcb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.088
inherited metabolic disorder DOID:655 0 0.085
disease of cellular proliferation DOID:14566 0 0.018
amino acid metabolic disorder DOID:9252 0 0.013
organic acidemia DOID:0060159 0 0.013
immune system disease DOID:2914 0 0.010
disease of anatomical entity DOID:7 0 0.010
hematopoietic system disease DOID:74 0 0.010