Mus musculus

271 known processes

Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

(Aliases: SEMA1,SemD,Semad,coll-1,Hsema-I)

Sema3a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
trunk neural crest cell migration GO:0036484 4 0.812
stem cell development GO:0048864 219 0.767
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.715
striated muscle tissue development GO:0014706 293 0.664
sympathetic neuron projection guidance GO:0097491 4 0.662
regulation of cellular amino acid metabolic process GO:0006521 5 0.502
blood vessel morphogenesis GO:0048514 285 0.490
Zebrafish Mouse
axon guidance GO:0007411 141 0.478
regulation of organelle organization GO:0033043 289 0.476
Worm
axonogenesis GO:0007409 274 0.457
cellular amine metabolic process GO:0044106 44 0.456
ventral trunk neural crest cell migration GO:0036486 4 0.456
negative regulation of phosphorus metabolic process GO:0010563 184 0.447
Mouse
heart morphogenesis GO:0003007 178 0.442
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.440
neuron projection extension GO:1990138 64 0.429
negative regulation of phosphate metabolic process GO:0045936 184 0.425
Mouse
gland development GO:0048732 330 0.413
muscle tissue development GO:0060537 308 0.409
stem cell differentiation GO:0048863 268 0.400
cell adhesion GO:0007155 329 0.399
Worm
positive regulation of cellular amine metabolic process GO:0033240 5 0.398
telencephalon development GO:0021537 186 0.377
autonomic nervous system development GO:0048483 43 0.366
negative regulation of axon guidance GO:1902668 8 0.355
regulation of cellular component size GO:0032535 121 0.345
branching involved in salivary gland morphogenesis GO:0060445 26 0.345
negative regulation of neuron differentiation GO:0045665 101 0.344
morphogenesis of a branching structure GO:0001763 203 0.344
sympathetic ganglion development GO:0061549 9 0.338
chemotaxis GO:0006935 247 0.331
regulation of cellular amine metabolic process GO:0033238 20 0.331
branching morphogenesis of an epithelial tube GO:0048754 159 0.330
Zebrafish
g protein coupled receptor signaling pathway GO:0007186 243 0.329
regulation of response to wounding GO:1903034 189 0.325
appendage development GO:0048736 166 0.324
cellular ketone metabolic process GO:0042180 84 0.324
wnt signaling pathway GO:0016055 188 0.323
motor neuron axon guidance GO:0008045 26 0.319
positive regulation of protein modification process GO:0031401 299 0.306
Mouse
regionalization GO:0003002 337 0.305
mapk cascade GO:0000165 281 0.304
epithelial tube morphogenesis GO:0060562 303 0.304
Zebrafish Mouse
positive regulation of neuron projection development GO:0010976 79 0.294
Mouse
peptidyl amino acid modification GO:0018193 336 0.293
Mouse
cellular homeostasis GO:0019725 240 0.282
ras protein signal transduction GO:0007265 77 0.278
regulation of axon extension GO:0030516 43 0.276
developmental cell growth GO:0048588 84 0.275
substrate dependent cell migration GO:0006929 18 0.266
rho protein signal transduction GO:0007266 32 0.261
canonical wnt signaling pathway GO:0060070 130 0.256
skeletal system development GO:0001501 356 0.256
Mouse
embryonic placenta development GO:0001892 98 0.249
angiogenesis GO:0001525 201 0.239
Zebrafish Mouse
actin cytoskeleton organization GO:0030036 220 0.238
Worm
negative chemotaxis GO:0050919 14 0.238
negative regulation of nervous system development GO:0051961 156 0.232
sympathetic neuron projection extension GO:0097490 4 0.230
regulation of protein kinase activity GO:0045859 232 0.227
positive regulation of cell development GO:0010720 237 0.225
regulation of canonical wnt signaling pathway GO:0060828 82 0.222
regulation of neuron apoptotic process GO:0043523 122 0.222
regulation of cell size GO:0008361 72 0.222
regulation of homeostatic process GO:0032844 182 0.219
cell substrate adhesion GO:0031589 130 0.206
regulation of cellular ketone metabolic process GO:0010565 66 0.205
negative regulation of cell development GO:0010721 169 0.202
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.202
neuron migration GO:0001764 122 0.201
apoptotic signaling pathway GO:0097190 306 0.201
morphogenesis of a branching epithelium GO:0061138 193 0.197
embryonic organ morphogenesis GO:0048562 276 0.191
regulation of chemotaxis GO:0050920 53 0.191
regulation of body fluid levels GO:0050878 162 0.185
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.182
regulation of cell adhesion GO:0030155 154 0.179
Worm
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.178
amine metabolic process GO:0009308 45 0.173
hindbrain development GO:0030902 128 0.173
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.168
Mouse
negative regulation of axon extension GO:0030517 19 0.167
labyrinthine layer development GO:0060711 49 0.167
calcium ion homeostasis GO:0055074 127 0.166
ear morphogenesis GO:0042471 118 0.166
muscle cell differentiation GO:0042692 261 0.165
Mouse
cellular amino acid metabolic process GO:0006520 103 0.165
central nervous system neuron differentiation GO:0021953 162 0.164
developmental growth involved in morphogenesis GO:0060560 138 0.163
organonitrogen compound catabolic process GO:1901565 264 0.162
Mouse
regulation of hydrolase activity GO:0051336 246 0.161
Mouse
urogenital system development GO:0001655 261 0.161
regulation of cytokine production GO:0001817 266 0.158
negative regulation of hormone metabolic process GO:0032351 4 0.158
immune effector process GO:0002252 321 0.157
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.157
trunk segmentation GO:0035290 4 0.157
forebrain development GO:0030900 302 0.155
regulation of mapk cascade GO:0043408 248 0.155
placenta development GO:0001890 140 0.154
lymphocyte differentiation GO:0030098 242 0.153
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.152
cardiac muscle tissue development GO:0048738 130 0.150
av node cell to bundle of his cell communication GO:0086067 2 0.150
purine nucleotide metabolic process GO:0006163 302 0.149
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.149
cation homeostasis GO:0055080 212 0.146
cell matrix adhesion GO:0007160 68 0.145
regulation of cell cycle GO:0051726 281 0.145
regulation of cell projection organization GO:0031344 206 0.143
epithelial cell migration GO:0010631 63 0.142
regulation of neuron projection development GO:0010975 169 0.140
metal ion homeostasis GO:0055065 189 0.140
sensory organ morphogenesis GO:0090596 242 0.138
neural precursor cell proliferation GO:0061351 121 0.138
single organism cell adhesion GO:0098602 156 0.136
positive regulation of nervous system development GO:0051962 221 0.136
nucleotide metabolic process GO:0009117 332 0.132
Mouse
cytoplasmic transport GO:0016482 234 0.132
regulation of intracellular transport GO:0032386 159 0.132
cell growth GO:0016049 130 0.132
negative regulation of cellular component organization GO:0051129 194 0.129
carbohydrate derivative biosynthetic process GO:1901137 183 0.129
neuronal action potential GO:0019228 54 0.128
inflammatory response GO:0006954 244 0.128
positive regulation of mapk cascade GO:0043410 170 0.128
positive regulation of protein phosphorylation GO:0001934 242 0.124
Mouse
cell fate commitment GO:0045165 210 0.124
neural crest cell migration GO:0001755 32 0.124
positive regulation of map kinase activity GO:0043406 84 0.123
facial nerve structural organization GO:0021612 10 0.122
embryonic appendage morphogenesis GO:0035113 126 0.121
morphogenesis of embryonic epithelium GO:0016331 159 0.120
Mouse Worm
neuron projection guidance GO:0097485 141 0.119
limb morphogenesis GO:0035108 149 0.119
tube formation GO:0035148 140 0.118
Mouse
regulation of vasculature development GO:1901342 88 0.118
Mouse
ribose phosphate metabolic process GO:0019693 291 0.117
Mouse
regulation of neuron differentiation GO:0045664 281 0.115
regulation of wnt signaling pathway GO:0030111 123 0.114
leukocyte differentiation GO:0002521 342 0.114
Mouse
regulation of ion homeostasis GO:2000021 64 0.114
mesenchyme development GO:0060485 152 0.112
somite development GO:0061053 81 0.112
ribonucleoside triphosphate metabolic process GO:0009199 220 0.111
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.111
regulation of cellular response to growth factor stimulus GO:0090287 82 0.109
cellular metal ion homeostasis GO:0006875 151 0.109
nucleoside phosphate metabolic process GO:0006753 338 0.109
Mouse
sympathetic nervous system development GO:0048485 22 0.108
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.108
ameboidal type cell migration GO:0001667 128 0.107
salivary gland development GO:0007431 37 0.106
pallium development GO:0021543 120 0.105
peptidyl tyrosine phosphorylation GO:0018108 143 0.105
Mouse
positive regulation of neuron projection regeneration GO:0070572 2 0.103
positive regulation of kinase activity GO:0033674 155 0.103
extrinsic apoptotic signaling pathway GO:0097191 126 0.103
ganglion development GO:0061548 13 0.102
circulatory system process GO:0003013 197 0.102
limb development GO:0060173 166 0.101
positive regulation of apoptotic process GO:0043065 217 0.101
negative regulation of cellular protein metabolic process GO:0032269 247 0.101
Mouse
sequestering of calcium ion GO:0051208 18 0.101
regulation of cellular response to stress GO:0080135 159 0.100
response to growth factor GO:0070848 198 0.100
regulation of cell migration GO:0030334 219 0.099
development of primary sexual characteristics GO:0045137 143 0.099
establishment of neuroblast polarity GO:0045200 1 0.099
lymphocyte proliferation GO:0046651 164 0.098
muscle contraction GO:0006936 101 0.098
cellular chemical homeostasis GO:0055082 215 0.098
organophosphate biosynthetic process GO:0090407 122 0.098
positive regulation of cell migration GO:0030335 109 0.097
negative regulation of protein phosphorylation GO:0001933 126 0.097
Mouse
negative regulation of blood vessel morphogenesis GO:2000181 25 0.096
Mouse
positive regulation of axon extension GO:0045773 20 0.096
neuron death GO:0070997 154 0.096
commissural neuron axon guidance GO:0071679 8 0.095
maintenance of location GO:0051235 89 0.095
neuron apoptotic process GO:0051402 142 0.095
forebrain neuron differentiation GO:0021879 52 0.093
cellular ion homeostasis GO:0006873 165 0.093
cell cell junction organization GO:0045216 72 0.092
camera type eye development GO:0043010 266 0.092
developmental maturation GO:0021700 193 0.092
Mouse
metencephalon development GO:0022037 89 0.091
Mouse
homeostasis of number of cells GO:0048872 210 0.091
microtubule cytoskeleton organization GO:0000226 157 0.090
transmembrane transport GO:0055085 412 0.090
response to molecule of bacterial origin GO:0002237 143 0.090
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.088
cell type specific apoptotic process GO:0097285 268 0.088
salivary gland morphogenesis GO:0007435 33 0.087
nucleotide catabolic process GO:0009166 217 0.086
Mouse
retinal ganglion cell axon guidance GO:0031290 18 0.086
positive regulation of transferase activity GO:0051347 167 0.086
hippocampus development GO:0021766 52 0.086
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.086
gastrulation GO:0007369 116 0.085
cellular lipid metabolic process GO:0044255 323 0.085
bone development GO:0060348 120 0.085
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.085
Mouse
central nervous system neuron development GO:0021954 67 0.085
protein localization to organelle GO:0033365 185 0.084
myeloid cell differentiation GO:0030099 233 0.083
tissue migration GO:0090130 68 0.083
facial nerve morphogenesis GO:0021610 11 0.082
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.082
Mouse
digestive tract development GO:0048565 190 0.082
negative regulation of angiogenesis GO:0016525 25 0.081
Mouse
protein polymerization GO:0051258 57 0.081
purine ribonucleotide metabolic process GO:0009150 290 0.081
Mouse
regulation of muscle system process GO:0090257 80 0.080
cerebellum vasculature morphogenesis GO:0061301 1 0.080
purine containing compound metabolic process GO:0072521 311 0.079
Mouse
purine nucleoside metabolic process GO:0042278 241 0.079
Mouse
cerebellum development GO:0021549 77 0.079
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.078
Worm
leukocyte migration GO:0050900 124 0.078
digestive tract morphogenesis GO:0048546 147 0.077
axonal fasciculation GO:0007413 15 0.077
positive regulation of cell projection organization GO:0031346 95 0.076
Mouse
regulation of cell growth GO:0001558 91 0.076
cerebral cortex development GO:0021987 86 0.076
cellular calcium ion homeostasis GO:0006874 119 0.076
negative regulation of vasculature development GO:1901343 26 0.075
Mouse
regulation of axon guidance GO:1902667 13 0.075
positive regulation of cell adhesion GO:0045785 80 0.075
negative regulation of protein metabolic process GO:0051248 282 0.075
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.074
Mouse
negative regulation of immune system process GO:0002683 209 0.074
negative regulation of behavior GO:0048521 14 0.074
ion transmembrane transport GO:0034220 361 0.074
t cell activation GO:0042110 289 0.073
Mouse
regulation of map kinase activity GO:0043405 120 0.073
learning or memory GO:0007611 148 0.073
cranial nerve development GO:0021545 41 0.073
positive regulation of cytokine production GO:0001819 174 0.073
regulation of extent of cell growth GO:0061387 52 0.072
progesterone secretion GO:0042701 1 0.072
regulation of protein binding GO:0043393 60 0.071
nucleobase containing small molecule metabolic process GO:0055086 352 0.071
Mouse
wound healing GO:0042060 157 0.071
neural tube development GO:0021915 160 0.071
Mouse
regulation of cell motility GO:2000145 236 0.071
positive regulation of chemotaxis GO:0050921 38 0.071
regulation of protein serine threonine kinase activity GO:0071900 157 0.071
actin filament based movement GO:0030048 23 0.070
regulation of lymphocyte activation GO:0051249 240 0.070
negative regulation of chemotaxis GO:0050922 11 0.070
ear development GO:0043583 200 0.069
heterocycle catabolic process GO:0046700 280 0.069
Mouse
ribonucleotide metabolic process GO:0009259 291 0.069
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.069
calcium ion transport GO:0006816 159 0.068
stem cell proliferation GO:0072089 117 0.068
oligodendrocyte differentiation GO:0048709 53 0.068
cation transport GO:0006812 399 0.067
renal system development GO:0072001 225 0.067
parasympathetic nervous system development GO:0048486 19 0.067
appendage morphogenesis GO:0035107 149 0.067
negative regulation of neuron death GO:1901215 98 0.067
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.067
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.066
vegf activated neuropilin signaling pathway involved in axon guidance GO:1902378 1 0.066
substrate dependent cerebral cortex tangential migration GO:0021825 3 0.066
regulation of defense response GO:0031347 233 0.066
exocrine system development GO:0035272 45 0.066
regulation of rho protein signal transduction GO:0035023 71 0.065
Mouse
sensory perception GO:0007600 245 0.065
regulation of reproductive process GO:2000241 66 0.065
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.065
branchiomotor neuron axon guidance GO:0021785 7 0.065
mesenchymal cell differentiation GO:0048762 107 0.065
regulation of neuron death GO:1901214 134 0.064
epithelial tube formation GO:0072175 130 0.064
Mouse
second messenger mediated signaling GO:0019932 73 0.064
cell recognition GO:0008037 83 0.063
regulation of cell activation GO:0050865 289 0.063
stress activated mapk cascade GO:0051403 80 0.063
muscle cell development GO:0055001 133 0.063
sa node cell action potential GO:0086015 4 0.063
cell differentiation involved in embryonic placenta development GO:0060706 26 0.063
cell activation involved in immune response GO:0002263 126 0.063
Mouse
rhythmic process GO:0048511 174 0.063
telencephalon cell migration GO:0022029 55 0.063
meiotic cell cycle GO:0051321 122 0.063
regulation of erk1 and erk2 cascade GO:0070372 71 0.062
gtp metabolic process GO:0046039 144 0.062
Mouse
cell chemotaxis GO:0060326 81 0.062
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.062
purine nucleoside triphosphate metabolic process GO:0009144 226 0.062
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.061
nerve development GO:0021675 67 0.061
bmp signaling pathway GO:0030509 93 0.060
negative regulation of hepatocyte differentiation GO:0070367 1 0.060
regulation of angiogenesis GO:0045765 81 0.060
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.060
single organismal cell cell adhesion GO:0016337 131 0.059
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.059
positive regulation of programmed cell death GO:0043068 218 0.059
response to lipopolysaccharide GO:0032496 128 0.059
organelle assembly GO:0070925 177 0.059
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.059
cardiac muscle cell differentiation GO:0055007 69 0.058
nucleoside metabolic process GO:0009116 246 0.057
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.057
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.057
muscle fiber development GO:0048747 76 0.057
cardiac muscle contraction GO:0060048 32 0.057
negative regulation of phosphorylation GO:0042326 166 0.057
Mouse
regulation of transferase activity GO:0051338 263 0.057
cellular response to growth factor stimulus GO:0071363 197 0.056
neural crest cell development GO:0014032 48 0.056
cell junction organization GO:0034330 77 0.056
divalent inorganic cation homeostasis GO:0072507 138 0.056
positive regulation of cell motility GO:2000147 116 0.056
segmentation GO:0035282 93 0.055
transmission of nerve impulse GO:0019226 76 0.055
regulation of protein localization GO:0032880 231 0.054
action potential GO:0001508 78 0.054
lung alveolus development GO:0048286 45 0.054
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.053
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.053
cytosolic calcium ion transport GO:0060401 48 0.053
somitogenesis GO:0001756 69 0.053
digestive system development GO:0055123 200 0.053
regulation of heart contraction GO:0008016 77 0.053
regulation of nucleotide metabolic process GO:0006140 169 0.053
Mouse
mesenchymal cell development GO:0014031 93 0.053
cytosolic calcium ion homeostasis GO:0051480 70 0.052
regulation of anatomical structure size GO:0090066 178 0.052
smooth muscle contraction GO:0006939 44 0.052
peptidyl tyrosine modification GO:0018212 145 0.052
Mouse
facioacoustic ganglion development GO:1903375 3 0.052
carbohydrate transport GO:0008643 62 0.052
cardiac ventricle development GO:0003231 83 0.052
organonitrogen compound biosynthetic process GO:1901566 192 0.052
positive regulation of cell growth GO:0030307 33 0.051
macromolecule catabolic process GO:0009057 281 0.051
cytokine production GO:0001816 319 0.050
protein kinase b signaling GO:0043491 74 0.050
purine ribonucleoside metabolic process GO:0046128 241 0.050
Mouse
ensheathment of neurons GO:0007272 76 0.050
gonad development GO:0008406 141 0.050
organophosphate catabolic process GO:0046434 232 0.050
Mouse
anatomical structure arrangement GO:0048532 20 0.049
myelination GO:0042552 74 0.049
positive regulation of defense response GO:0031349 124 0.049
nuclear transport GO:0051169 139 0.049
regulation of ion transmembrane transport GO:0034765 119 0.049
establishment or maintenance of neuroblast polarity GO:0045196 1 0.049
regulation of cellular catabolic process GO:0031329 242 0.049
Mouse
endocytosis GO:0006897 168 0.049
negative regulation of neuron apoptotic process GO:0043524 92 0.048
negative regulation of phospholipase activity GO:0010519 4 0.048
regulation of mitotic cell cycle GO:0007346 126 0.048
positive regulation of stress activated mapk cascade GO:0032874 48 0.048
nucleoside phosphate biosynthetic process GO:1901293 79 0.048
positive regulation of behavior GO:0048520 40 0.048
negative regulation of cell proliferation GO:0008285 296 0.048
mesodermal cell migration GO:0008078 4 0.047
cerebellum vasculature development GO:0061300 1 0.047
response to organonitrogen compound GO:0010243 246 0.047
posttranscriptional regulation of gene expression GO:0010608 155 0.047
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.047
regulation of ion transport GO:0043269 215 0.046
muscle tissue morphogenesis GO:0060415 53 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.046
Mouse
actin polymerization or depolymerization GO:0008154 54 0.046
cellular response to acid chemical GO:0071229 68 0.046
regulation of cytoplasmic transport GO:1903649 112 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.046
regulation of multi organism process GO:0043900 111 0.045
response to radiation GO:0009314 165 0.045
Fly
anatomical structure maturation GO:0071695 49 0.045
Mouse
mitotic cell cycle GO:0000278 195 0.045
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.045
purine nucleoside catabolic process GO:0006152 205 0.045
Mouse
renal system process GO:0003014 48 0.045
positive regulation of ion transport GO:0043270 65 0.045
asymmetric neuroblast division GO:0055059 1 0.045
response to acid chemical GO:0001101 111 0.045
microtubule based process GO:0007017 236 0.044
regulation of leukocyte differentiation GO:1902105 159 0.044
nucleoside phosphate catabolic process GO:1901292 222 0.044
Mouse
purine nucleotide biosynthetic process GO:0006164 65 0.044
regulation of establishment of protein localization GO:0070201 181 0.044
purine ribonucleoside catabolic process GO:0046130 205 0.044
Mouse
regulation of protein transport GO:0051223 163 0.044
axon extension involved in axon guidance GO:0048846 14 0.044
membrane organization GO:0061024 245 0.043
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.043
carbohydrate derivative catabolic process GO:1901136 231 0.043
Mouse
jnk cascade GO:0007254 72 0.043
carbohydrate metabolic process GO:0005975 230 0.043
organelle localization GO:0051640 179 0.043
Mouse
sequestering of metal ion GO:0051238 19 0.043
regulation of rho gtpase activity GO:0032319 58 0.043
Mouse
semaphorin plexin signaling pathway GO:0071526 21 0.043
sprouting angiogenesis GO:0002040 26 0.043
purine nucleotide catabolic process GO:0006195 211 0.042
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.042
regulation of nucleotide catabolic process GO:0030811 122 0.042
Mouse
regulation of jnk cascade GO:0046328 62 0.042
cellular protein complex assembly GO:0043623 116 0.042
granulocyte chemotaxis GO:0071621 39 0.042
actin mediated cell contraction GO:0070252 15 0.041
trigeminal nerve morphogenesis GO:0021636 6 0.041
i kappab kinase nf kappab signaling GO:0007249 85 0.041
regulation of t cell proliferation GO:0042129 92 0.041
t cell differentiation GO:0030217 174 0.041
Mouse
epithelium migration GO:0090132 63 0.041
regulation of protein secretion GO:0050708 82 0.040
negative regulation of protein modification process GO:0031400 163 0.040
Mouse
germ cell development GO:0007281 185 0.040
regulation of actin cytoskeleton organization GO:0032956 84 0.040
Worm
multicellular organismal homeostasis GO:0048871 164 0.040
purine containing compound catabolic process GO:0072523 213 0.040
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.040
synaptic transmission GO:0007268 329 0.040
positive regulation of jun kinase activity GO:0043507 30 0.040
release of sequestered calcium ion into cytosol GO:0051209 42 0.040
cell proliferation in midbrain GO:0033278 2 0.039
cellular response to cytokine stimulus GO:0071345 189 0.039
regulation of ion transmembrane transporter activity GO:0032412 54 0.039
positive regulation of jnk cascade GO:0046330 46 0.039
regulation of system process GO:0044057 200 0.039
anatomical structure homeostasis GO:0060249 145 0.039
striated muscle cell development GO:0055002 125 0.039
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.039
positive regulation of t cell activation GO:0050870 101 0.038
glial cell differentiation GO:0010001 131 0.038
protein import GO:0017038 101 0.038
positive regulation of angiogenesis GO:0045766 46 0.038
regulation of t cell activation GO:0050863 170 0.038
lens development in camera type eye GO:0002088 62 0.038
dorsal ventral axon guidance GO:0033563 3 0.038
intracellular protein transport GO:0006886 204 0.037
vascular process in circulatory system GO:0003018 62 0.037
protein processing GO:0016485 163 0.037
positive regulation of cellular component biogenesis GO:0044089 94 0.037
hormone secretion GO:0046879 128 0.037
positive regulation of protein kinase activity GO:0045860 144 0.037
rac protein signal transduction GO:0016601 13 0.037
negative regulation of cellular amine metabolic process GO:0033239 1 0.037
female gonad development GO:0008585 71 0.037
synapse assembly GO:0007416 56 0.037
regulation of secretion GO:0051046 274 0.037
peptidyl serine modification GO:0018209 83 0.036
nuclear import GO:0051170 95 0.036
response to inorganic substance GO:0010035 96 0.036
hypothalamus gonadotrophin releasing hormone neuron development GO:0021888 4 0.036
positive regulation of secretion GO:0051047 130 0.036
outflow tract morphogenesis GO:0003151 53 0.036
regulation of neural precursor cell proliferation GO:2000177 70 0.036
cardiac muscle cell development GO:0055013 39 0.036
tissue homeostasis GO:0001894 115 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
Mouse
epidermis development GO:0008544 187 0.035
erk1 and erk2 cascade GO:0070371 77 0.035
compound eye development GO:0048749 1 0.035
epithelial cell development GO:0002064 159 0.035
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.035
activation of mapk activity GO:0000187 59 0.035
glycoprotein biosynthetic process GO:0009101 89 0.035
divalent inorganic cation transport GO:0072511 178 0.035
protein maturation GO:0051604 176 0.035
protein localization to nucleus GO:0034504 121 0.035
kidney development GO:0001822 213 0.035
hindbrain morphogenesis GO:0021575 46 0.035
vegf activated neuropilin signaling pathway GO:0038190 2 0.035
regulation of transmembrane transport GO:0034762 128 0.034
synapse organization GO:0050808 125 0.034
aromatic compound catabolic process GO:0019439 286 0.034
Mouse
olfactory bulb development GO:0021772 30 0.034
Human
cell maturation GO:0048469 127 0.034
cartilage development GO:0051216 140 0.034
inner ear morphogenesis GO:0042472 101 0.034
substrate adhesion dependent cell spreading GO:0034446 30 0.034
positive chemotaxis GO:0050918 18 0.034
b cell activation GO:0042113 161 0.034
regulation of inflammatory response GO:0050727 147 0.034
negative regulation of hormone biosynthetic process GO:0032353 4 0.034
regulation of membrane potential GO:0042391 192 0.034
lipid biosynthetic process GO:0008610 179 0.034
regulation of renin secretion into blood stream GO:1900133 4 0.034
negative regulation of neuron projection development GO:0010977 50 0.034
nitrogen compound transport GO:0071705 271 0.033
phenol containing compound metabolic process GO:0018958 60 0.033
establishment of protein localization to organelle GO:0072594 118 0.033
regulation of hormone levels GO:0010817 211 0.033
hepaticobiliary system development GO:0061008 67 0.033
positive regulation of apoptotic signaling pathway GO:2001235 95 0.033

Sema3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org