Mus musculus

128 known processes

Ghr

growth hormone receptor

(Aliases: GHR/BP,GHBP,AA986417)

Ghr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neutral lipid metabolic process GO:0006638 57 0.999
regulation of fatty acid metabolic process GO:0019217 28 0.999
regulation of triglyceride metabolic process GO:0090207 17 0.998
acylglycerol metabolic process GO:0006639 55 0.998
regulation of fatty acid oxidation GO:0046320 10 0.997
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.997
steroid metabolic process GO:0008202 119 0.997
glycerolipid metabolic process GO:0046486 122 0.996
regulation of steroid biosynthetic process GO:0050810 26 0.995
positive regulation of lipid catabolic process GO:0050996 6 0.995
response to peptide hormone GO:0043434 127 0.994
triglyceride metabolic process GO:0006641 51 0.992
lipid catabolic process GO:0016042 69 0.992
sterol homeostasis GO:0055092 45 0.991
cholesterol homeostasis GO:0042632 44 0.988
regulation of androgen receptor signaling pathway GO:0060765 3 0.988
monocarboxylic acid metabolic process GO:0032787 191 0.986
regulation of lipid metabolic process GO:0019216 118 0.983
regulation of steroid metabolic process GO:0019218 39 0.981
positive regulation of lipid metabolic process GO:0045834 40 0.979
fatty acid metabolic process GO:0006631 121 0.978
cholesterol storage GO:0010878 4 0.978
regulation of mapk cascade GO:0043408 248 0.976
Rat
regulation of lipid catabolic process GO:0050994 15 0.976
positive regulation of triglyceride metabolic process GO:0090208 9 0.975
intracellular receptor signaling pathway GO:0030522 74 0.971
regulation of fatty acid beta oxidation GO:0031998 1 0.971
regulation of insulin receptor signaling pathway GO:0046626 21 0.970
taurine metabolic process GO:0019530 4 0.966
creatinine metabolic process GO:0046449 3 0.966
carboxylic acid catabolic process GO:0046395 51 0.962
hormone mediated signaling pathway GO:0009755 23 0.956
Mouse Rat
oxidation reduction process GO:0055114 342 0.955
urogenital system development GO:0001655 261 0.953
Mouse
cellular lipid metabolic process GO:0044255 323 0.952
positive regulation of fatty acid oxidation GO:0046321 4 0.948
regulation of feeding behavior GO:0060259 3 0.948
carbohydrate homeostasis GO:0033500 128 0.944
mapk cascade GO:0000165 281 0.944
Rat
response to testosterone GO:0033574 3 0.943
carbohydrate metabolic process GO:0005975 230 0.941
positive regulation of lipid biosynthetic process GO:0046889 18 0.940
canonical wnt signaling pathway involved in metanephric kidney development GO:0061290 2 0.932
rhythmic process GO:0048511 174 0.930
insulin receptor signaling pathway GO:0008286 49 0.927
regulation of steroid hormone biosynthetic process GO:0090030 4 0.926
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.926
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.922
acylglycerol homeostasis GO:0055090 16 0.922
negative regulation of kinase activity GO:0033673 81 0.920
regulation of protein targeting GO:1903533 61 0.919
cellular response to hormone stimulus GO:0032870 150 0.918
regulation of blood pressure GO:0008217 93 0.917
steroid biosynthetic process GO:0006694 47 0.916
cellular response to peptide GO:1901653 92 0.914
cellular lipid catabolic process GO:0044242 52 0.914
cellular carbohydrate metabolic process GO:0044262 119 0.910
ovulation cycle GO:0042698 59 0.910
energy derivation by oxidation of organic compounds GO:0015980 77 0.904
negative regulation of transferase activity GO:0051348 85 0.898
multicellular organism growth GO:0035264 161 0.896
lipid homeostasis GO:0055088 63 0.896
sulfur compound metabolic process GO:0006790 100 0.892
lipid biosynthetic process GO:0008610 179 0.886
positive regulation of hormone biosynthetic process GO:0046886 1 0.886
antral ovarian follicle growth GO:0001547 5 0.886
female gonad development GO:0008585 71 0.884
positive regulation of glycogen metabolic process GO:0070875 8 0.883
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.874
protein localization to organelle GO:0033365 185 0.872
triglyceride homeostasis GO:0070328 15 0.867
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.865
small molecule catabolic process GO:0044282 71 0.863
cellular ketone metabolic process GO:0042180 84 0.862
cellular response to insulin stimulus GO:0032869 78 0.860
Rat
cellular response to peptide hormone stimulus GO:0071375 92 0.858
positive regulation of fatty acid beta oxidation GO:0032000 1 0.856
type i pneumocyte differentiation GO:0060509 7 0.853
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.849
generation of precursor metabolites and energy GO:0006091 103 0.846
lipid transport GO:0006869 98 0.840
regulation of cellular ketone metabolic process GO:0010565 66 0.835
positive regulation of cholesterol homeostasis GO:2000189 2 0.835
regulation of secretion GO:0051046 274 0.834
regulation of glucose metabolic process GO:0010906 60 0.832
cytoplasmic transport GO:0016482 234 0.829
protein kinase b signaling GO:0043491 74 0.825
ovarian follicle development GO:0001541 40 0.819
regulation of carbohydrate metabolic process GO:0006109 75 0.818
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.816
progesterone metabolic process GO:0042448 4 0.816
regulation of cholesterol storage GO:0010885 4 0.808
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.808
positive regulation of intracellular steroid hormone receptor signaling pathway GO:0033145 4 0.806
regulation of transferase activity GO:0051338 263 0.802
Rat
regulation of cholesterol homeostasis GO:2000188 9 0.799
acylglycerol biosynthetic process GO:0046463 18 0.798
regulation of glycogen metabolic process GO:0070873 13 0.797
peptidyl amino acid modification GO:0018193 336 0.786
negative regulation of phosphorylation GO:0042326 166 0.783
regulation of camp metabolic process GO:0030814 30 0.782
regulation of cell motility GO:2000145 236 0.780
protein localization to nucleus GO:0034504 121 0.780
response to nutrient levels GO:0031667 109 0.779
Rat
energy reserve metabolic process GO:0006112 39 0.779
response to organonitrogen compound GO:0010243 246 0.779
negative regulation of molecular function GO:0044092 258 0.777
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.773
establishment of protein localization to organelle GO:0072594 118 0.773
monosaccharide metabolic process GO:0005996 106 0.773
wnt signaling pathway involved in kidney development GO:0061289 2 0.773
glycerolipid biosynthetic process GO:0045017 50 0.772
protein lipid complex subunit organization GO:0071825 12 0.771
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.764
negative regulation of blood pressure GO:0045776 22 0.762
regulation of lipid biosynthetic process GO:0046890 54 0.753
regulation of cellular amine metabolic process GO:0033238 20 0.748
ear development GO:0043583 200 0.748
negative regulation of phosphorus metabolic process GO:0010563 184 0.740
gland development GO:0048732 330 0.736
Mouse
prostate gland development GO:0030850 48 0.736
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.736
water homeostasis GO:0030104 27 0.726
lipid storage GO:0019915 36 0.725
fatty acid catabolic process GO:0009062 25 0.724
cyclic purine nucleotide metabolic process GO:0052652 43 0.723
monocarboxylic acid catabolic process GO:0072329 27 0.718
response to insulin GO:0032868 100 0.717
Rat
lipid localization GO:0010876 126 0.717
organic acid catabolic process GO:0016054 51 0.716
single organism nuclear import GO:1902593 95 0.713
triglyceride catabolic process GO:0019433 9 0.710
cellular amine metabolic process GO:0044106 44 0.709
regulation of systemic arterial blood pressure GO:0003073 61 0.702
cellular response to growth factor stimulus GO:0071363 197 0.701
amine metabolic process GO:0009308 45 0.700
cellular carbohydrate catabolic process GO:0044275 15 0.695
negative regulation of intracellular signal transduction GO:1902532 167 0.694
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.691
ribonucleotide biosynthetic process GO:0009260 59 0.691
polysaccharide metabolic process GO:0005976 39 0.690
regulation of cellular catabolic process GO:0031329 242 0.689
positive regulation of mapk cascade GO:0043410 170 0.688
Rat
positive regulation of carbohydrate metabolic process GO:0045913 30 0.683
cellular lactam metabolic process GO:0072338 3 0.678
regulation of intracellular transport GO:0032386 159 0.676
cholesterol transport GO:0030301 38 0.675
positive regulation of camp mediated signaling GO:0043950 3 0.674
phospholipid metabolic process GO:0006644 87 0.674
regulation of protein import into nucleus translocation GO:0033158 2 0.667
camera type eye development GO:0043010 266 0.667
alpha amino acid metabolic process GO:1901605 59 0.666
positive regulation of lipid kinase activity GO:0090218 11 0.663
negative regulation of triglyceride metabolic process GO:0090209 4 0.660
positive regulation of cholesterol transport GO:0032376 9 0.660
prostate gland morphogenesis GO:0060512 32 0.655
regulation of nucleotide biosynthetic process GO:0030808 34 0.652
trophectodermal cellular morphogenesis GO:0001831 3 0.650
regulation of natural killer cell differentiation GO:0032823 11 0.648
lipid modification GO:0030258 65 0.647
cell proliferation in hindbrain GO:0021534 10 0.644
positive regulation of glial cell proliferation GO:0060252 4 0.644
regulation of triglyceride biosynthetic process GO:0010866 10 0.643
cytokine mediated signaling pathway GO:0019221 115 0.642
peptidyl tyrosine phosphorylation GO:0018108 143 0.637
cellular response to organonitrogen compound GO:0071417 145 0.633
nuclear import GO:0051170 95 0.633
negative regulation of cellular protein metabolic process GO:0032269 247 0.632
cellular amino acid metabolic process GO:0006520 103 0.632
citrate metabolic process GO:0006101 3 0.631
organ growth GO:0035265 117 0.627
Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.625
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.625
circulatory system process GO:0003013 197 0.618
cholesterol metabolic process GO:0008203 56 0.617
regulation of carbohydrate catabolic process GO:0043470 12 0.617
positive regulation of lipoprotein lipase activity GO:0051006 3 0.616
tissue remodeling GO:0048771 102 0.612
regulation of kinase activity GO:0043549 249 0.611
Rat
hormone metabolic process GO:0042445 86 0.611
myeloid cell differentiation GO:0030099 233 0.609
sensory organ morphogenesis GO:0090596 242 0.609
nuclear transport GO:0051169 139 0.605
development of primary sexual characteristics GO:0045137 143 0.604
positive regulation of glucose metabolic process GO:0010907 21 0.602
sterol catabolic process GO:0016127 5 0.599
regulation of hormone secretion GO:0046883 88 0.599
glycolytic process GO:0006096 20 0.599
sulfur compound biosynthetic process GO:0044272 37 0.598
glucose import GO:0046323 32 0.598
regulation of mesenchymal cell proliferation GO:0010464 37 0.595
regulation of generation of precursor metabolites and energy GO:0043467 38 0.595
positive regulation of glycogen starch synthase activity GO:2000467 4 0.593
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.592
glucan metabolic process GO:0044042 32 0.591
circadian regulation of gene expression GO:0032922 48 0.590
glycogen biosynthetic process GO:0005978 14 0.587
regulation of protein transport GO:0051223 163 0.585
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.582
blood circulation GO:0008015 195 0.579
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.573
sensory perception of umami taste GO:0050917 4 0.567
regulation of protein import into nucleus GO:0042306 52 0.566
canonical wnt signaling pathway GO:0060070 130 0.565
response to extracellular stimulus GO:0009991 127 0.563
Rat
plasma membrane long chain fatty acid transport GO:0015911 1 0.556
regulation of cellular amino acid metabolic process GO:0006521 5 0.556
regulation of glucan biosynthetic process GO:0010962 7 0.555
pyruvate metabolic process GO:0006090 28 0.550
valine metabolic process GO:0006573 4 0.548
negative regulation of cell proliferation GO:0008285 296 0.547
positive regulation of steroid biosynthetic process GO:0010893 4 0.546
epithelial cell development GO:0002064 159 0.545
morphogenesis of a branching epithelium GO:0061138 193 0.544
glucose homeostasis GO:0042593 128 0.539
intracellular protein transport GO:0006886 204 0.537
response to peptide GO:1901652 136 0.536
muscle cell differentiation GO:0042692 261 0.533
male germ line stem cell asymmetric division GO:0048133 2 0.533
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.531
regulation of carbohydrate biosynthetic process GO:0043255 40 0.531
development of secondary male sexual characteristics GO:0046544 3 0.530
maternal process involved in female pregnancy GO:0060135 32 0.528
regulation of intestinal cholesterol absorption GO:0030300 4 0.527
negative regulation of peptide hormone secretion GO:0090278 16 0.526
negative regulation of epithelial cell proliferation GO:0050680 64 0.526
sterol transport GO:0015918 38 0.526
prostate gland growth GO:0060736 13 0.526
Mouse
regulation of glucose transport GO:0010827 32 0.525
positive regulation of camp metabolic process GO:0030816 19 0.523
regulation of protein localization GO:0032880 231 0.519
regulation of hormone levels GO:0010817 211 0.518
response to oxygen levels GO:0070482 62 0.516
response to organic cyclic compound GO:0014070 198 0.515
Human Rat
creatine metabolic process GO:0006600 4 0.512
regulation of myeloid leukocyte differentiation GO:0002761 58 0.512
wnt signaling pathway GO:0016055 188 0.511
glucan biosynthetic process GO:0009250 14 0.506
neutral lipid biosynthetic process GO:0046460 18 0.506
gonad development GO:0008406 141 0.506
regulation of peptide secretion GO:0002791 77 0.505
female genitalia development GO:0030540 14 0.504
isoleucine metabolic process GO:0006549 4 0.502
positive regulation of protein modification process GO:0031401 299 0.502
regulation of protein localization to nucleus GO:1900180 60 0.498
acylglycerol catabolic process GO:0046464 11 0.493
eating behavior GO:0042755 15 0.492
regulation of peptide hormone secretion GO:0090276 75 0.491
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.490
protein import into nucleus GO:0006606 95 0.490
cellular chemical homeostasis GO:0055082 215 0.489
response to steroid hormone GO:0048545 56 0.488
Human Rat
positive regulation of adenylate cyclase activity GO:0045762 8 0.487
negative regulation of endothelial cell migration GO:0010596 4 0.487
negative regulation of lipid metabolic process GO:0045833 30 0.486
erythrocyte differentiation GO:0030218 88 0.483
regulation of macrophage activation GO:0043030 17 0.480
polysaccharide biosynthetic process GO:0000271 20 0.478
positive regulation of activated t cell proliferation GO:0042104 8 0.477
lactation GO:0007595 25 0.477
Mouse
response to growth hormone GO:0060416 7 0.472
nuclear envelope organization GO:0006998 11 0.466
regulation of erk1 and erk2 cascade GO:0070372 71 0.465
intestinal cholesterol absorption GO:0030299 5 0.460
maintenance of location GO:0051235 89 0.459
cellular response to increased oxygen levels GO:0036295 1 0.458
response to decreased oxygen levels GO:0036293 59 0.458
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.451
negative regulation of protein metabolic process GO:0051248 282 0.450
synaptic transmission GO:0007268 329 0.449
female sex differentiation GO:0046660 84 0.449
carbohydrate transport GO:0008643 62 0.447
reactive nitrogen species metabolic process GO:2001057 0 0.443
regulation of nucleocytoplasmic transport GO:0046822 73 0.441
positive regulation of stem cell proliferation GO:2000648 59 0.438
positive regulation of apoptotic signaling pathway GO:2001235 95 0.437
acetate ester metabolic process GO:1900619 3 0.436
triglyceride biosynthetic process GO:0019432 17 0.436
response to purine containing compound GO:0014074 28 0.434
mammary gland lobule development GO:0061377 22 0.432
Mouse
prostate glandular acinus development GO:0060525 12 0.431
protein dna complex subunit organization GO:0071824 28 0.430
sterol metabolic process GO:0016125 58 0.425
regulation of defense response GO:0031347 233 0.421
fatty acid oxidation GO:0019395 28 0.418
fatty acid transport GO:0015908 28 0.415
positive regulation of smooth muscle cell migration GO:0014911 4 0.410
regulation of camp mediated signaling GO:0043949 7 0.410
cardiac muscle tissue development GO:0048738 130 0.410
nucleocytoplasmic transport GO:0006913 139 0.409
response to caffeine GO:0031000 6 0.408
nucleotide biosynthetic process GO:0009165 78 0.408
regulation of cell migration GO:0030334 219 0.406
spermatogenesis GO:0007283 284 0.403
positive regulation of organelle organization GO:0010638 128 0.402
carbohydrate derivative biosynthetic process GO:1901137 183 0.401
ribose phosphate biosynthetic process GO:0046390 59 0.401
regulation of establishment of protein localization GO:0070201 181 0.399
regulation of intracellular protein transport GO:0033157 82 0.398
epithelial tube morphogenesis GO:0060562 303 0.396
development of primary female sexual characteristics GO:0046545 73 0.395
steroid hormone mediated signaling pathway GO:0043401 6 0.395
plasma lipoprotein particle organization GO:0071827 11 0.395
positive regulation of cell activation GO:0050867 158 0.394
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.391
mammary gland branching involved in pregnancy GO:0060745 6 0.390
anatomical structure homeostasis GO:0060249 145 0.390
amide transport GO:0042886 138 0.389
glucose import in response to insulin stimulus GO:0044381 8 0.387
negative regulation of insulin secretion GO:0046676 14 0.380
succinate metabolic process GO:0006105 4 0.379
bone development GO:0060348 120 0.376
Rat
germline stem cell asymmetric division GO:0098728 2 0.376
sertoli cell development GO:0060009 15 0.371
eye photoreceptor cell differentiation GO:0001754 41 0.369
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.366
reactive oxygen species biosynthetic process GO:1903409 8 0.364
trophectodermal cell proliferation GO:0001834 2 0.361
insulin secretion GO:0030073 89 0.361
regulation of camp biosynthetic process GO:0030817 25 0.360
epithelial cell proliferation GO:0050673 174 0.358
glycogen metabolic process GO:0005977 32 0.358
regulation of leukocyte differentiation GO:1902105 159 0.357
positive regulation of kinase activity GO:0033674 155 0.357
Rat
cellular water homeostasis GO:0009992 2 0.356
positive regulation of lipid storage GO:0010884 10 0.355
regulation of nitrogen cycle metabolic process GO:1903314 1 0.353
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.351
response to corticosteroid GO:0031960 20 0.347
Rat
regulation of body fluid levels GO:0050878 162 0.347
Mouse
negative regulation of neuron death GO:1901215 98 0.346
Rat
positive regulation of hormone metabolic process GO:0032352 3 0.346
negative regulation of peptide secretion GO:0002792 16 0.342
membrane organization GO:0061024 245 0.339
positive regulation of protein phosphorylation GO:0001934 242 0.338
regulation of vasculature development GO:1901342 88 0.336
protein import GO:0017038 101 0.335
regulation of gluconeogenesis GO:0006111 30 0.334
positive regulation of fibroblast proliferation GO:0048146 20 0.333
morphogenesis of a branching structure GO:0001763 203 0.332
organic hydroxy compound metabolic process GO:1901615 203 0.331
ossification GO:0001503 216 0.330
negative regulation of phosphate metabolic process GO:0045936 184 0.330
positive regulation of camp biosynthetic process GO:0030819 19 0.329
metanephric tubule development GO:0072170 18 0.327
lung cell differentiation GO:0060479 30 0.322
male sex differentiation GO:0046661 109 0.322
cellular glucan metabolic process GO:0006073 32 0.321
regulation of system process GO:0044057 200 0.319
regulation of acetylcholine metabolic process GO:0060408 1 0.319
retina development in camera type eye GO:0060041 119 0.319
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.318
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis GO:0060527 7 0.317
negative regulation of intracellular transport GO:0032387 38 0.316
peptide secretion GO:0002790 114 0.315
receptor biosynthetic process GO:0032800 3 0.311
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.311
regulation of leukocyte proliferation GO:0070663 121 0.308
cellular response to nutrient levels GO:0031669 64 0.308
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.307
locomotory behavior GO:0007626 195 0.306
camp metabolic process GO:0046058 40 0.305
regulation of p38mapk cascade GO:1900744 3 0.304
regulation of protein kinase b signaling GO:0051896 56 0.303
proteoglycan biosynthetic process GO:0030166 20 0.303
coagulation GO:0050817 78 0.299
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 0.298
branching involved in prostate gland morphogenesis GO:0060442 15 0.298
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 2 0.297
small molecule biosynthetic process GO:0044283 132 0.297
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.295
cerebellar granule cell precursor proliferation GO:0021930 10 0.294
drug catabolic process GO:0042737 2 0.293
aminoglycan metabolic process GO:0006022 34 0.292
regulation of protein kinase activity GO:0045859 232 0.292
Rat
regulation of wnt signaling pathway GO:0030111 123 0.290
cellular response to growth hormone stimulus GO:0071378 7 0.290
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.290
glucocorticoid mediated signaling pathway GO:0043402 3 0.289
negative regulation of cellular component organization GO:0051129 194 0.288
positive regulation of fatty acid metabolic process GO:0045923 8 0.284
female gamete generation GO:0007292 74 0.283
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.283
germ line stem cell division GO:0042078 2 0.282
protein processing GO:0016485 163 0.281
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.280
negative regulation of endothelial cell proliferation GO:0001937 8 0.279
metanephric nephron development GO:0072210 34 0.278
positive regulation of chromosome organization GO:2001252 33 0.277
positive regulation of retinoic acid receptor signaling pathway GO:0048386 3 0.277
circadian rhythm GO:0007623 114 0.277
carbohydrate biosynthetic process GO:0016051 74 0.277
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.277
dna metabolic process GO:0006259 303 0.276
regulation of organelle organization GO:0033043 289 0.276
negative regulation of reactive oxygen species biosynthetic process GO:1903427 0 0.275
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.274
innate immune response activating signal transduction GO:0002758 50 0.273
regulation of lipoprotein lipase activity GO:0051004 4 0.273
cyclic nucleotide metabolic process GO:0009187 59 0.272
response to alcohol GO:0097305 48 0.272
Human
divalent inorganic cation transport GO:0072511 178 0.272
male gamete generation GO:0048232 285 0.271
regulation of lipid transport GO:0032368 36 0.270
regulation of cholesterol transport GO:0032374 17 0.269
inner ear receptor cell differentiation GO:0060113 61 0.267
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.267
organic acid transport GO:0015849 101 0.267
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.266
response to radiation GO:0009314 165 0.265
response to food GO:0032094 17 0.265
Rat
regulation of cellular response to stress GO:0080135 159 0.264
purine containing compound biosynthetic process GO:0072522 70 0.262
negative regulation of bone remodeling GO:0046851 6 0.261
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.261
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.259
maintenance of cell number GO:0098727 3 0.259
regulation of cellular response to growth factor stimulus GO:0090287 82 0.257
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.256
positive regulation of sterol transport GO:0032373 9 0.256
regulation of renal sodium excretion GO:0035813 3 0.256
hormone secretion GO:0046879 128 0.256
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.256
jak stat cascade GO:0007259 42 0.255
Mouse Rat
cellular response to lipid GO:0071396 145 0.255
mammary gland morphogenesis GO:0060443 54 0.255
mammary gland duct morphogenesis GO:0060603 38 0.254
inner ear receptor cell development GO:0060119 39 0.253
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 11 0.252
response to low density lipoprotein particle GO:0055098 2 0.252
muscle cell proliferation GO:0033002 52 0.252
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.252
positive regulation of lymphocyte proliferation GO:0050671 70 0.249
reactive oxygen species metabolic process GO:0072593 84 0.249
glycerolipid catabolic process GO:0046503 16 0.248
regulation of lyase activity GO:0051339 13 0.248
regulation of erythrocyte differentiation GO:0045646 23 0.246
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.245
calcium mediated signaling GO:0019722 46 0.243
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.241
positive regulation of inositol trisphosphate biosynthetic process GO:0032962 2 0.237
peptide transport GO:0015833 133 0.237
regulation of activated t cell proliferation GO:0046006 16 0.237
regulation of response to oxidative stress GO:1902882 19 0.237
embryonic organ morphogenesis GO:0048562 276 0.236
regulation of myeloid cell differentiation GO:0045637 96 0.235
regulation of proteolysis GO:0030162 164 0.235
response to reactive oxygen species GO:0000302 56 0.235
cholesterol efflux GO:0033344 24 0.235
positive regulation of glycogen biosynthetic process GO:0045725 6 0.235
erk1 and erk2 cascade GO:0070371 77 0.234
organophosphate biosynthetic process GO:0090407 122 0.233
sensory system development GO:0048880 3 0.233
glucagon secretion GO:0070091 3 0.230
negative regulation of hormone secretion GO:0046888 20 0.229
negative regulation of bmp signaling pathway GO:0030514 35 0.229
negative regulation of protein transport GO:0051224 46 0.229
organonitrogen compound biosynthetic process GO:1901566 192 0.228
asymmetric stem cell division GO:0098722 3 0.228
second messenger mediated signaling GO:0019932 73 0.226
kidney development GO:0001822 213 0.226
retina morphogenesis in camera type eye GO:0060042 45 0.226
regulation of fatty acid biosynthetic process GO:0042304 12 0.224
cardiac chamber development GO:0003205 108 0.223
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.223
positive regulation of triglyceride catabolic process GO:0010898 3 0.223
regulation of phosphatidylcholine catabolic process GO:0010899 2 0.222
positive regulation of glucose import in response to insulin stimulus GO:2001275 5 0.221
carbohydrate catabolic process GO:0016052 32 0.220
phospholipid homeostasis GO:0055091 6 0.219
positive regulation of nervous system development GO:0051962 221 0.218
lateral line system development GO:0048925 1 0.217
intestinal absorption GO:0050892 13 0.217
skin development GO:0043588 220 0.217
blood vessel morphogenesis GO:0048514 285 0.216
regulation of apoptotic signaling pathway GO:2001233 197 0.216
negative regulation of cellular response to insulin stimulus GO:1900077 16 0.216
positive regulation of glucose import GO:0046326 14 0.215
appendage development GO:0048736 166 0.214
ammonia assimilation cycle GO:0019676 2 0.213
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 8 0.213
sensory perception GO:0007600 245 0.213
negative regulation of protein phosphorylation GO:0001933 126 0.213
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.213
metanephric glomerulus development GO:0072224 13 0.213
positive regulation of peptide secretion GO:0002793 33 0.212
regulation of innate immune response GO:0045088 91 0.212
high density lipoprotein particle assembly GO:0034380 3 0.212
regulation of lipid storage GO:0010883 20 0.211
anion transport GO:0006820 177 0.209

Ghr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.645
Human
diabetes mellitus DOID:9351 0 0.620
type 2 diabetes mellitus DOID:9352 0 0.620
carbohydrate metabolism disease DOID:0050013 0 0.620
glucose metabolism disease DOID:4194 0 0.620
acquired metabolic disease DOID:0060158 0 0.620
inherited metabolic disorder DOID:655 0 0.456
Human
disease of anatomical entity DOID:7 0 0.239
nervous system disease DOID:863 0 0.239