Mus musculus

98 known processes

Cd40lg

CD40 ligand

(Aliases: IMD3,HIGM1,CD40-L,Tnfsf5,Cd40l,CD154,Ly62,gp39,TRAP,IGM,T-BAM,Ly-62)

Cd40lg biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular ketone metabolic process GO:0010565 66 0.824
defense response to other organism GO:0098542 197 0.819
Mouse Fly
t helper 2 cell cytokine production GO:0035745 4 0.748
immune effector process GO:0002252 321 0.742
amine metabolic process GO:0009308 45 0.738
regulation of cellular amino acid metabolic process GO:0006521 5 0.734
leukocyte differentiation GO:0002521 342 0.708
regulation of interleukin 13 secretion GO:2000665 2 0.692
regulation of leukocyte mediated immunity GO:0002703 104 0.651
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.569
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.550
Mouse
regulation of interleukin 5 secretion GO:2000662 2 0.529
interleukin 5 secretion GO:0072603 2 0.520
adaptive immune response GO:0002250 155 0.516
negative regulation of growth GO:0045926 99 0.488
Mouse
cellular ketone metabolic process GO:0042180 84 0.472
regulation of lymphocyte activation GO:0051249 240 0.457
Mouse Rat
regulation of lymphocyte mediated immunity GO:0002706 84 0.446
Mouse
defense response to bacterium GO:0042742 119 0.442
Mouse Fly
cytokine production GO:0001816 319 0.432
Mouse Rat
positive regulation of cellular amine metabolic process GO:0033240 5 0.428
cellular amino acid metabolic process GO:0006520 103 0.428
cellular amine metabolic process GO:0044106 44 0.417
lymphocyte differentiation GO:0030098 242 0.413
b cell proliferation GO:0042100 53 0.407
Rat
regulation of cytokine production GO:0001817 266 0.406
Mouse Rat
cytokine production involved in immune response GO:0002367 34 0.386
b cell activation GO:0042113 161 0.382
negative regulation of interleukin 13 secretion GO:2000666 1 0.358
interleukin 10 secretion GO:0072608 4 0.355
regulation of cell activation GO:0050865 289 0.351
Mouse Rat
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.342
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.340
Mouse
leukocyte mediated immunity GO:0002443 174 0.314
peptidyl tyrosine modification GO:0018212 145 0.307
positive regulation of protein modification process GO:0031401 299 0.304
Mouse
humoral immune response GO:0006959 57 0.290
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.288
cellular response to cytokine stimulus GO:0071345 189 0.277
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 40 0.274
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.269
defense response to gram positive bacterium GO:0050830 50 0.268
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.259
Mouse
b cell activation involved in immune response GO:0002312 50 0.257
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.254
regulation of secretion GO:0051046 274 0.253
interleukin 13 secretion GO:0072611 2 0.247
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.247
negative regulation of interleukin 13 production GO:0032696 2 0.240
negative regulation of cellular amine metabolic process GO:0033239 1 0.238
cytokine biosynthetic process GO:0042089 68 0.236
regulation of lymphocyte proliferation GO:0050670 117 0.227
Rat
nitrogen compound transport GO:0071705 271 0.220
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.213
regulation of b cell proliferation GO:0030888 39 0.213
Rat
negative regulation of leukocyte differentiation GO:1902106 51 0.207
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.197
Mouse
dna metabolic process GO:0006259 303 0.196
interspecies interaction between organisms GO:0044419 83 0.194
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.193
Rat
regulation of gtp catabolic process GO:0033124 113 0.192
positive regulation of secretion GO:0051047 130 0.187
Mouse
regulation of secretion by cell GO:1903530 249 0.181
somatic diversification of immune receptors GO:0002200 53 0.181
peptidyl tyrosine phosphorylation GO:0018108 143 0.180
cation transport GO:0006812 399 0.180
lymphocyte activation involved in immune response GO:0002285 93 0.179
positive regulation of secretion by cell GO:1903532 114 0.177
Mouse
positive regulation of b cell activation GO:0050871 49 0.172
Rat
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.168
growth of symbiont involved in interaction with host GO:0044116 23 0.163
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.161
Mouse
immunoglobulin secretion GO:0048305 17 0.160
lymphocyte proliferation GO:0046651 164 0.159
Rat
positive regulation of cell activation GO:0050867 158 0.158
Mouse Rat
anatomical structure homeostasis GO:0060249 145 0.155
Mouse Fly
peptidyl amino acid modification GO:0018193 336 0.154
positive regulation of chemokine biosynthetic process GO:0045080 6 0.152
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.151
regulation of establishment of protein localization GO:0070201 181 0.147
immunoglobulin production GO:0002377 73 0.139
regulation of b cell mediated immunity GO:0002712 37 0.138
Mouse
regulation of interleukin 10 secretion GO:2001179 4 0.135
t cell differentiation GO:0030217 174 0.134
regulation of t cell proliferation GO:0042129 92 0.133
regulation of ion transport GO:0043269 215 0.130
Mouse
circadian rhythm GO:0007623 114 0.129
production of molecular mediator of immune response GO:0002440 103 0.128
cytokine mediated signaling pathway GO:0019221 115 0.128
Mouse
sensitization GO:0046960 2 0.127
positive regulation of immune effector process GO:0002699 107 0.124
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.124
regulation of membrane potential GO:0042391 192 0.124
bone remodeling GO:0046849 53 0.123
Mouse
positive regulation of mapk cascade GO:0043410 170 0.122
Mouse
negative regulation of t cell activation GO:0050868 65 0.121
regulation of leukocyte proliferation GO:0070663 121 0.120
Rat
somatic diversification of immunoglobulins GO:0016445 43 0.119
tissue homeostasis GO:0001894 115 0.116
Mouse
acid secretion GO:0046717 33 0.111
Mouse
synaptic transmission GO:0007268 329 0.110
Fly
negative regulation of cell activation GO:0050866 111 0.109
lymphocyte mediated immunity GO:0002449 139 0.109
anion transport GO:0006820 177 0.108
Mouse
corticotropin releasing hormone secretion GO:0043396 2 0.107
Mouse
negative regulation of interleukin 5 secretion GO:2000663 1 0.107
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.107
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.106
leukocyte proliferation GO:0070661 172 0.104
Mouse Rat
heat generation GO:0031649 13 0.103
Mouse
ras protein signal transduction GO:0007265 77 0.102
positive regulation of cell death GO:0010942 224 0.102
Mouse
cell activation involved in immune response GO:0002263 126 0.101
regulation of multi organism process GO:0043900 111 0.100
Mouse
homeostasis of number of cells GO:0048872 210 0.098
forebrain development GO:0030900 302 0.097
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.094
cell growth GO:0016049 130 0.094
glucose transport GO:0015758 56 0.094
Mouse
glial cell apoptotic process GO:0034349 3 0.091
regulation of nucleotide catabolic process GO:0030811 122 0.090
regulation of t helper 2 cell cytokine production GO:2000551 3 0.089
positive regulation of dna recombination GO:0045911 17 0.089
tyrosine phosphorylation of stat protein GO:0007260 23 0.089
purine containing compound metabolic process GO:0072521 311 0.088
positive regulation of innate immune response GO:0045089 80 0.085
cellular response to lipid GO:0071396 145 0.084
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.084
Mouse
myeloid cell differentiation GO:0030099 233 0.083
Mouse
protein localization to organelle GO:0033365 185 0.083
Mouse
negative regulation of interleukin 5 production GO:0032714 4 0.083
regulation of cytokine production involved in immune response GO:0002718 26 0.082
extrinsic apoptotic signaling pathway GO:0097191 126 0.082
Mouse Fly
positive regulation of neuron differentiation GO:0045666 141 0.080
protein kinase b signaling GO:0043491 74 0.080
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.079
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.079
t cell activation GO:0042110 289 0.078
Mouse
positive regulation of cytokine production GO:0001819 174 0.078
Mouse Rat
regulation of t cell activation GO:0050863 170 0.077
Mouse
negative regulation of immune effector process GO:0002698 55 0.077
dna recombination GO:0006310 92 0.076
positive regulation of cell development GO:0010720 237 0.076
Mouse
response to acid chemical GO:0001101 111 0.075
Mouse
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.074
neuronal action potential GO:0019228 54 0.073
ossification GO:0001503 216 0.073
Mouse
positive regulation of b cell mediated immunity GO:0002714 26 0.072
Mouse
muscle cell differentiation GO:0042692 261 0.072
Mouse
regulation of type 2 immune response GO:0002828 18 0.072
positive regulation of t cell activation GO:0050870 101 0.071
Mouse
positive regulation of mhc class ii biosynthetic process GO:0045348 4 0.071
Rat
jak stat cascade GO:0007259 42 0.071
action potential GO:0001508 78 0.070
cellular response to acid chemical GO:0071229 68 0.070
Mouse
rhodopsin mediated signaling pathway GO:0016056 4 0.070
negative regulation of protein modification process GO:0031400 163 0.069
regulation of metal ion transport GO:0010959 106 0.069
regulation of neuron differentiation GO:0045664 281 0.068
regulation of coagulation GO:0050818 31 0.068
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.067
Mouse
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.067
Mouse
gtp catabolic process GO:0006184 143 0.066
skin development GO:0043588 220 0.066
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.065
positive regulation of cell division GO:0051781 31 0.065
regulation of response to wounding GO:1903034 189 0.065
Mouse
glycosyl compound metabolic process GO:1901657 246 0.064
positive regulation of hormone secretion GO:0046887 38 0.063
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.063
cation homeostasis GO:0055080 212 0.063
Mouse
regulation of immunoglobulin production GO:0002637 42 0.062
leukocyte activation involved in immune response GO:0002366 126 0.062
defense response to gram negative bacterium GO:0050829 28 0.062
Fly
organophosphate catabolic process GO:0046434 232 0.062
sodium ion transport GO:0006814 73 0.061
negative regulation of cytokine production GO:0001818 84 0.061
positive regulation of programmed cell death GO:0043068 218 0.060
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.060
inflammatory response GO:0006954 244 0.059
Mouse
monosaccharide transport GO:0015749 58 0.059
Mouse
response to extracellular stimulus GO:0009991 127 0.059
negative regulation of molecular function GO:0044092 258 0.059
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.058
negative regulation of phosphorus metabolic process GO:0010563 184 0.058
Mouse
epithelial tube morphogenesis GO:0060562 303 0.058
glycosyl compound catabolic process GO:1901658 206 0.058
regulation of interleukin 6 production GO:0032675 55 0.057
Mouse
calcium ion homeostasis GO:0055074 127 0.057
Mouse
detection of external stimulus GO:0009581 61 0.057
response to reactive oxygen species GO:0000302 56 0.057
regulation of kinase activity GO:0043549 249 0.056
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.055
Mouse
regulation of action potential GO:0098900 4 0.055
camera type eye development GO:0043010 266 0.055
somatic cell dna recombination GO:0016444 51 0.053
regulation of cellular catabolic process GO:0031329 242 0.053
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.053
Mouse
regulation of chemokine production GO:0032642 30 0.053
heterocycle catabolic process GO:0046700 280 0.053
regulation of innate immune response GO:0045088 91 0.052
temperature homeostasis GO:0001659 26 0.052
Mouse
cell division GO:0051301 120 0.051
negative regulation of cell proliferation GO:0008285 296 0.051
posttranscriptional regulation of gene expression GO:0010608 155 0.051
Mouse
regulation of production of molecular mediator of immune response GO:0002700 65 0.051
positive regulation of phospholipase c activity GO:0010863 2 0.051
purine nucleoside metabolic process GO:0042278 241 0.050
regulation of organelle organization GO:0033043 289 0.050
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.049
digestive tract development GO:0048565 190 0.049
multicellular organismal signaling GO:0035637 91 0.049
mapk cascade GO:0000165 281 0.049
Mouse Fly
cellular ion homeostasis GO:0006873 165 0.049
regulation of reactive oxygen species metabolic process GO:2000377 40 0.049
Mouse
positive regulation of homeostatic process GO:0032846 64 0.049
Mouse
sensory organ morphogenesis GO:0090596 242 0.048
Mouse
multicellular organismal homeostasis GO:0048871 164 0.048
Mouse
response to inorganic substance GO:0010035 96 0.048
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.047
peptide transport GO:0015833 133 0.047
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.047
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.047
Mouse
b cell differentiation GO:0030183 78 0.046
transmission of nerve impulse GO:0019226 76 0.045
purine nucleotide catabolic process GO:0006195 211 0.045
regulation of nucleoside metabolic process GO:0009118 130 0.045
defense response to virus GO:0051607 68 0.045
positive regulation of defense response GO:0031349 124 0.045
Mouse
cellular response to inorganic substance GO:0071241 37 0.045
nucleoside phosphate metabolic process GO:0006753 338 0.045
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.045
sensory perception GO:0007600 245 0.044
positive regulation of peptide hormone secretion GO:0090277 31 0.044
Mouse
cellular response to biotic stimulus GO:0071216 92 0.044
Mouse
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.044
regulation of adaptive immune response GO:0002819 90 0.044
Mouse
amide transport GO:0042886 138 0.044
Mouse
regulation of chemokine biosynthetic process GO:0045073 8 0.044
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.044
myeloid leukocyte differentiation GO:0002573 119 0.044
Mouse
growth involved in symbiotic interaction GO:0044110 23 0.043
Mouse
aromatic compound catabolic process GO:0019439 286 0.043
alpha beta t cell differentiation GO:0046632 69 0.043
positive regulation of lymphocyte activation GO:0051251 140 0.043
Mouse Rat
regulation of cell migration GO:0030334 219 0.043
Mouse
regulation of tyrosine phosphorylation of stat protein GO:0042509 20 0.043
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.043
leukocyte migration GO:0050900 124 0.043
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.042
regulation of b cell activation GO:0050864 81 0.042
Rat
organonitrogen compound catabolic process GO:1901565 264 0.042
organic acid transport GO:0015849 101 0.042
Mouse
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.042
t cell mediated immunity GO:0002456 50 0.042
regulation of peptide secretion GO:0002791 77 0.042
Mouse
bone resorption GO:0045453 38 0.042
Mouse
negative regulation of t cell differentiation GO:0045581 23 0.042
negative regulation of immune system process GO:0002683 209 0.041
regulation of heart contraction GO:0008016 77 0.041
cellular response to lipopolysaccharide GO:0071222 77 0.041
Mouse
positive regulation of gtpase activity GO:0043547 85 0.040
regulation of cell projection organization GO:0031344 206 0.040
regulation of jak stat cascade GO:0046425 34 0.040
positive regulation of gtp catabolic process GO:0033126 85 0.040
peptide secretion GO:0002790 114 0.040
Mouse
t cell proliferation GO:0042098 120 0.040
regulation of immunoglobulin mediated immune response GO:0002889 37 0.039
Mouse
alpha beta t cell activation GO:0046631 91 0.039
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.039
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.039
striated muscle tissue development GO:0014706 293 0.038
Mouse
response to growth factor GO:0070848 198 0.038
purine ribonucleotide metabolic process GO:0009150 290 0.038
ribonucleoside catabolic process GO:0042454 206 0.038
positive regulation of b cell proliferation GO:0030890 24 0.037
Rat
apoptotic signaling pathway GO:0097190 306 0.037
Mouse Fly
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.037
Mouse
response to amino acid GO:0043200 37 0.037
Mouse
negative regulation of b cell proliferation GO:0030889 13 0.037
myelination GO:0042552 74 0.037
positive regulation of nucleoside metabolic process GO:0045979 91 0.037
regulation of protein transport GO:0051223 163 0.036
regulation of cellular response to stress GO:0080135 159 0.036
Mouse
regulation of isotype switching GO:0045191 22 0.036
regulation of protein localization GO:0032880 231 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.036
guanosine containing compound metabolic process GO:1901068 144 0.036
positive regulation of t cell proliferation GO:0042102 52 0.036
regulation of hormone secretion GO:0046883 88 0.036
Mouse
negative regulation of cellular component organization GO:0051129 194 0.036
t helper cell differentiation GO:0042093 28 0.035
purine nucleoside catabolic process GO:0006152 205 0.035
intrinsic apoptotic signaling pathway GO:0097193 132 0.035
Mouse
nucleoside catabolic process GO:0009164 206 0.035
regulation of map kinase activity GO:0043405 120 0.035
Mouse
t helper 2 cell differentiation GO:0045064 12 0.035
nuclear division GO:0000280 158 0.035
organic cyclic compound catabolic process GO:1901361 295 0.035
cellular response to oxidative stress GO:0034599 76 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
cytokine secretion GO:0050663 72 0.034
regulation of cell cycle GO:0051726 281 0.034
positive regulation of organelle organization GO:0010638 128 0.034
regulation of fever generation by regulation of prostaglandin secretion GO:0071810 2 0.034
Mouse
translational initiation GO:0006413 24 0.034
Mouse
nucleoside metabolic process GO:0009116 246 0.034
telencephalon development GO:0021537 186 0.034
oxidation reduction process GO:0055114 342 0.034
regulation of intracellular transport GO:0032386 159 0.033
Mouse
negative regulation of adaptive immune response GO:0002820 25 0.033
positive regulation of jak stat cascade GO:0046427 22 0.033
erk1 and erk2 cascade GO:0070371 77 0.033
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.033
Mouse
ribonucleotide catabolic process GO:0009261 208 0.033
regulation of t cell differentiation GO:0045580 83 0.033
lymphocyte costimulation GO:0031294 15 0.033
Mouse
regulation of transferase activity GO:0051338 263 0.033
Mouse
gland development GO:0048732 330 0.033
Mouse
intracellular protein transport GO:0006886 204 0.033
Mouse
calcium ion transport GO:0006816 159 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
epithelial cell proliferation GO:0050673 174 0.032
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.032
Mouse
regulation of transmembrane transport GO:0034762 128 0.032
regulation of growth of symbiont in host GO:0044126 19 0.032
Mouse
positive regulation of kinase activity GO:0033674 155 0.032
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
cell differentiation involved in embryonic placenta development GO:0060706 26 0.031
negative regulation of lymphocyte differentiation GO:0045620 32 0.031
retina development in camera type eye GO:0060041 119 0.031
protein processing GO:0016485 163 0.031
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.031
multicellular organismal metabolic process GO:0044236 28 0.031
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
negative regulation of ossification GO:0030279 49 0.030
Mouse
response to nutrient levels GO:0031667 109 0.030
reactive oxygen species metabolic process GO:0072593 84 0.030
Mouse
isotype switching to igg isotypes GO:0048291 10 0.030
positive regulation of intracellular transport GO:0032388 70 0.030
Mouse
regulation of cell division GO:0051302 76 0.030
myeloid dendritic cell activation GO:0001773 25 0.030
hormone secretion GO:0046879 128 0.030
Mouse
nucleotide catabolic process GO:0009166 217 0.030
regulation of system process GO:0044057 200 0.030
negative regulation of organelle organization GO:0010639 90 0.030
response to organonitrogen compound GO:0010243 246 0.030
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.030
mammary gland lobule development GO:0061377 22 0.030
Mouse
carbohydrate transport GO:0008643 62 0.030
Mouse
detection of abiotic stimulus GO:0009582 60 0.029
cytosolic calcium ion homeostasis GO:0051480 70 0.029
gtp metabolic process GO:0046039 144 0.029
limbic system development GO:0021761 72 0.029
multicellular organism growth GO:0035264 161 0.029
lipid localization GO:0010876 126 0.029
Mouse
cell fate commitment GO:0045165 210 0.029
Fly
negative regulation of growth of symbiont in host GO:0044130 19 0.029
Mouse
single organism nuclear import GO:1902593 95 0.029
Mouse
regulation of chromosome organization GO:0033044 83 0.029
regulation of cell cycle process GO:0010564 160 0.029
metal ion homeostasis GO:0055065 189 0.029
Mouse
mitochondrion organization GO:0007005 134 0.028
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.028
Mouse
nucleotide metabolic process GO:0009117 332 0.028
developmental growth involved in morphogenesis GO:0060560 138 0.028
organic hydroxy compound metabolic process GO:1901615 203 0.028
Fly
peptide hormone secretion GO:0030072 109 0.028
Mouse
myeloid dendritic cell differentiation GO:0043011 16 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.028
bone morphogenesis GO:0060349 78 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
regulation of organ morphogenesis GO:2000027 144 0.028
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
regulation of cytokine secretion involved in immune response GO:0002739 4 0.028
carbohydrate metabolic process GO:0005975 230 0.027
Mouse
regulation of protein secretion GO:0050708 82 0.027
cell type specific apoptotic process GO:0097285 268 0.027
osteoclast differentiation GO:0030316 62 0.027
Mouse
positive regulation of isotype switching GO:0045830 15 0.027
regulation of anatomical structure size GO:0090066 178 0.027
myeloid leukocyte activation GO:0002274 83 0.027
negative regulation of b cell activation GO:0050869 27 0.027
positive regulation of leukocyte mediated immunity GO:0002705 70 0.027
Mouse
chemokine metabolic process GO:0050755 10 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
regulation of defense response GO:0031347 233 0.026
Mouse
negative regulation of protein transport GO:0051224 46 0.026
protein maturation GO:0051604 176 0.026
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.026
positive regulation of nervous system development GO:0051962 221 0.026
conditioned taste aversion GO:0001661 4 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
Mouse
protein secretion GO:0009306 111 0.025
regulation of protein kinase activity GO:0045859 232 0.025
Mouse
antimicrobial peptide production GO:0002775 2 0.025
regulation of protein maturation GO:1903317 96 0.025
negative regulation of lymphocyte proliferation GO:0050672 45 0.025
regulation of cell size GO:0008361 72 0.025
negative regulation of alpha beta t cell activation GO:0046636 18 0.025
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.025
Mouse
regulation of translation GO:0006417 71 0.025
Mouse
cellular response to external stimulus GO:0071496 88 0.025
positive regulation of immunoglobulin production GO:0002639 28 0.025
heart contraction GO:0060047 93 0.025
regulation of mapk cascade GO:0043408 248 0.024
Mouse
cellular homeostasis GO:0019725 240 0.024
Fly
carboxylic acid transport GO:0046942 100 0.024
Mouse
protein import into nucleus GO:0006606 95 0.024
Mouse
positive regulation of protein secretion GO:0050714 52 0.024
nuclear transport GO:0051169 139 0.024
Mouse
wnt signaling pathway GO:0016055 188 0.024
natural killer cell activation GO:0030101 44 0.024
positive regulation of protein transport GO:0051222 93 0.024
Mouse
response to oxidative stress GO:0006979 123 0.024
cognition GO:0050890 149 0.024
compound eye development GO:0048749 1 0.024
g protein coupled receptor signaling pathway GO:0007186 243 0.024
regulation of systemic arterial blood pressure GO:0003073 61 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
response to transforming growth factor beta GO:0071559 88 0.023
regulation of chronic inflammatory response to antigenic stimulus GO:0002874 3 0.023
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.023
Mouse
mammary gland alveolus development GO:0060749 22 0.023
Mouse
salivary gland development GO:0007431 37 0.023
Mouse
regulation of t helper cell differentiation GO:0045622 14 0.023
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.023
positive regulation of jun kinase activity GO:0043507 30 0.023
Mouse
positive regulation of macrophage activation GO:0043032 10 0.023
fear response GO:0042596 33 0.023
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.022
regulation of protein kinase b signaling GO:0051896 56 0.022
Mouse
male gamete generation GO:0048232 285 0.022
positive regulation of apoptotic signaling pathway GO:2001235 95 0.022
cellular response to abiotic stimulus GO:0071214 56 0.022
positive regulation of transferase activity GO:0051347 167 0.022
Mouse
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.022
regulation of circadian rhythm GO:0042752 58 0.022
response to endoplasmic reticulum stress GO:0034976 53 0.022
regulation of protein binding GO:0043393 60 0.022
chemokine biosynthetic process GO:0042033 8 0.022
regulation of muscle tissue development GO:1901861 97 0.022
Mouse
activation of immune response GO:0002253 138 0.022
leukocyte homeostasis GO:0001776 79 0.022
cellular calcium ion homeostasis GO:0006874 119 0.022
regulation of mast cell activation GO:0033003 21 0.022
activation of adenylate cyclase activity GO:0007190 4 0.022
regulation of ossification GO:0030278 112 0.022
Mouse
positive regulation of interleukin 13 production GO:0032736 4 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.022
positive regulation of alpha beta t cell activation GO:0046635 39 0.022
dna endoreduplication GO:0042023 4 0.022
regulation of translational initiation by iron GO:0006447 2 0.022
Mouse
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.022
positive regulation of map kinase activity GO:0043406 84 0.022
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.022
regulation of t cell mediated immunity GO:0002709 34 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
positive regulation of nucleotide catabolic process GO:0030813 88 0.021
photoreceptor cell differentiation GO:0046530 52 0.021
regulation of cell growth GO:0001558 91 0.021
regulation of alpha beta t cell differentiation GO:0046637 35 0.021
translation GO:0006412 93 0.021
Mouse
protein localization to nucleus GO:0034504 121 0.021
Mouse
regulation of anion transport GO:0044070 27 0.021
Mouse
negative regulation of leukocyte proliferation GO:0070664 46 0.021
positive regulation of protein complex assembly GO:0031334 45 0.021
cation transmembrane transport GO:0098655 266 0.021
regulation of protein catabolic process GO:0042176 108 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.021
regulation of feeding behavior GO:0060259 3 0.021
transmembrane transport GO:0055085 412 0.021
cytoplasmic transport GO:0016482 234 0.021
Mouse
response to drug GO:0042493 75 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
protein homooligomerization GO:0051260 43 0.021
Mouse
ensheathment of neurons GO:0007272 76 0.021
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
immune response regulating signaling pathway GO:0002764 125 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
negative regulation of cell growth GO:0030308 44 0.020
positive regulation of leukocyte differentiation GO:1902107 86 0.020
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.020
Rat
lipid transport GO:0006869 98 0.020
Mouse
interleukin 13 production GO:0032616 6 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
Mouse
positive regulation of ras gtpase activity GO:0032320 65 0.020
liver development GO:0001889 66 0.020

Cd40lg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.024
disease of anatomical entity DOID:7 0 0.024
disease of metabolism DOID:0014667 0 0.023