Mus musculus

53 known processes

Tcp1

t-complex protein 1

(Aliases: Tp63,p63,Ccta,CCT,Tcp-1,Cct1,TRic,AI528772,c-cpn)

Tcp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spindle assembly involved in mitosis GO:0090307 4 0.996
Fly
binding of sperm to zona pellucida GO:0007339 34 0.985
sperm egg recognition GO:0035036 37 0.954
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.907
Fly
toxin transport GO:1901998 38 0.889
cell cell recognition GO:0009988 44 0.813
organelle assembly GO:0070925 177 0.719
Fly
mitotic cell cycle process GO:1903047 159 0.591
Fly
fertilization GO:0009566 127 0.498
development of primary sexual characteristics GO:0045137 143 0.478
single fertilization GO:0007338 82 0.463
gonad development GO:0008406 141 0.444
nuclear division GO:0000280 158 0.423
Fly
mitotic nuclear division GO:0007067 48 0.408
Fly
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.389
genitalia development GO:0048806 37 0.371
cytoplasmic microtubule organization GO:0031122 14 0.265
organelle fission GO:0048285 170 0.250
Fly
mitotic cell cycle GO:0000278 195 0.241
Fly
cell recognition GO:0008037 83 0.239
microtubule based process GO:0007017 236 0.227
Fly
protein folding GO:0006457 28 0.190
Yeast
protein refolding GO:0042026 1 0.167
microtubule cytoskeleton organization GO:0000226 157 0.155
Fly
germ cell development GO:0007281 185 0.132
regulation of mitotic cell cycle GO:0007346 126 0.131
nucleoside triphosphate metabolic process GO:0009141 230 0.129
spindle organization GO:0007051 28 0.120
Fly
nucleotide catabolic process GO:0009166 217 0.114
centrosome cycle GO:0007098 23 0.106
ribonucleoside catabolic process GO:0042454 206 0.106
endocytosis GO:0006897 168 0.105
Fly
cell adhesion GO:0007155 329 0.103
regulation of cell cycle process GO:0010564 160 0.093
purine nucleoside triphosphate catabolic process GO:0009146 203 0.089
ribonucleotide catabolic process GO:0009261 208 0.088
receptor mediated endocytosis GO:0006898 51 0.087
ribonucleoside triphosphate catabolic process GO:0009203 199 0.084
purine nucleoside catabolic process GO:0006152 205 0.075
protein localization to nucleus GO:0034504 121 0.070
regulation of transposition GO:0010528 2 0.066
carbohydrate derivative catabolic process GO:1901136 231 0.066
cellular nitrogen compound catabolic process GO:0044270 280 0.065
mitotic spindle organization GO:0007052 10 0.059
Fly
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
spindle assembly GO:0051225 13 0.058
Fly
striated muscle tissue development GO:0014706 293 0.057
regulation of cell cycle GO:0051726 281 0.056
ribose phosphate metabolic process GO:0019693 291 0.054
translation GO:0006412 93 0.053
nuclear import GO:0051170 95 0.053
oocyte axis specification GO:0007309 2 0.053
oocyte anterior posterior axis specification GO:0007314 2 0.052
nucleoside phosphate metabolic process GO:0006753 338 0.052
purine ribonucleoside catabolic process GO:0046130 205 0.050
negative regulation of intracellular signal transduction GO:1902532 167 0.050
nucleoside phosphate catabolic process GO:1901292 222 0.049
oogenesis GO:0048477 56 0.048
female gamete generation GO:0007292 74 0.047
regulation of neuron differentiation GO:0045664 281 0.047
trna aminoacylation for protein translation GO:0006418 1 0.047
cytoplasmic transport GO:0016482 234 0.046
ribonucleotide metabolic process GO:0009259 291 0.045
atp catabolic process GO:0006200 55 0.045
oocyte construction GO:0007308 2 0.044
ribonucleoside monophosphate catabolic process GO:0009158 57 0.042
organophosphate biosynthetic process GO:0090407 122 0.041
nucleotide metabolic process GO:0009117 332 0.041
organophosphate catabolic process GO:0046434 232 0.041
glycosyl compound metabolic process GO:1901657 246 0.040
response to organonitrogen compound GO:0010243 246 0.039
regulation of protein localization GO:0032880 231 0.039
centrosome duplication GO:0051298 16 0.039
nucleoside metabolic process GO:0009116 246 0.038
nuclear transport GO:0051169 139 0.037
ion transmembrane transport GO:0034220 361 0.037
protein import GO:0017038 101 0.037
transmembrane transport GO:0055085 412 0.036
small gtpase mediated signal transduction GO:0007264 97 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
positive regulation of cell death GO:0010942 224 0.035
positive regulation of apoptotic process GO:0043065 217 0.034
positive regulation of cell cycle GO:0045787 92 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.034
regulation of establishment of protein localization GO:0070201 181 0.034
regulation of intracellular transport GO:0032386 159 0.034
negative regulation of cell proliferation GO:0008285 296 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.033
cytoplasmic translational initiation GO:0002183 3 0.033
cell type specific apoptotic process GO:0097285 268 0.033
protein import into nucleus GO:0006606 95 0.032
regulation of hydrolase activity GO:0051336 246 0.032
purine nucleoside metabolic process GO:0042278 241 0.032
purine containing compound metabolic process GO:0072521 311 0.032
regulation of cell growth GO:0001558 91 0.032
oocyte differentiation GO:0009994 35 0.031
blastocyst development GO:0001824 80 0.031
single organism nuclear import GO:1902593 95 0.031
response to acid chemical GO:0001101 111 0.031
cation transmembrane transport GO:0098655 266 0.031
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
purine containing compound catabolic process GO:0072523 213 0.030
regulation of cell division GO:0051302 76 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
regulation of cell projection organization GO:0031344 206 0.029
epithelial cell proliferation GO:0050673 174 0.029
regulation of cytoskeleton organization GO:0051493 122 0.029
leukocyte migration GO:0050900 124 0.029
regulation of transferase activity GO:0051338 263 0.029
gene silencing by rna GO:0031047 19 0.028
nucleoside catabolic process GO:0009164 206 0.028
microtubule organizing center organization GO:0031023 28 0.028
aromatic compound catabolic process GO:0019439 286 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
axonogenesis GO:0007409 274 0.028
glycosyl compound catabolic process GO:1901658 206 0.028
response to organic cyclic compound GO:0014070 198 0.028
regulation of organelle organization GO:0033043 289 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
pole plasm assembly GO:0007315 2 0.027
regulation of protein transport GO:0051223 163 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
amine metabolic process GO:0009308 45 0.026
regulation of cellular response to stress GO:0080135 159 0.025
regulation of cell cycle phase transition GO:1901987 77 0.025
muscle cell differentiation GO:0042692 261 0.025
nucleic acid transport GO:0050657 18 0.025
rna localization GO:0006403 23 0.025
cytokine production GO:0001816 319 0.025
regulation of nucleocytoplasmic transport GO:0046822 73 0.025
rna interference GO:0016246 2 0.024
cell maturation GO:0048469 127 0.024
positive regulation of intracellular protein transport GO:0090316 42 0.024
rna splicing GO:0008380 54 0.024
pore complex assembly GO:0046931 3 0.023
intracellular protein transport GO:0006886 204 0.023
t cell activation GO:0042110 289 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
oocyte development GO:0048599 33 0.022
regulation of peptidase activity GO:0052547 96 0.022
multicellular organismal signaling GO:0035637 91 0.022
positive regulation of intracellular transport GO:0032388 70 0.022
cellular amine metabolic process GO:0044106 44 0.022
ras protein signal transduction GO:0007265 77 0.021
g1 s transition of mitotic cell cycle GO:0000082 57 0.021
leukocyte proliferation GO:0070661 172 0.021
cellular amino acid metabolic process GO:0006520 103 0.021
protein targeting GO:0006605 143 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
maintenance of location GO:0051235 89 0.020
protein localization to organelle GO:0033365 185 0.020
developmental maturation GO:0021700 193 0.020
cell division GO:0051301 120 0.020
ossification GO:0001503 216 0.020
centrosome organization GO:0051297 26 0.020
regulation of cellular catabolic process GO:0031329 242 0.019
positive regulation of protein localization to nucleus GO:1900182 30 0.019
nucleobase containing compound transport GO:0015931 27 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
regulation of kinase activity GO:0043549 249 0.019
regulation of microtubule based process GO:0032886 52 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
atp metabolic process GO:0046034 75 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
regulation of gtp catabolic process GO:0033124 113 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
cellular protein complex assembly GO:0043623 116 0.018
positive regulation of protein transport GO:0051222 93 0.018
spermatogenesis GO:0007283 284 0.017
regulation of intracellular protein transport GO:0033157 82 0.017
trna aminoacylation GO:0043039 1 0.017
negative regulation of molecular function GO:0044092 258 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
regulation of cell motility GO:2000145 236 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
regulation of protein targeting GO:1903533 61 0.017
nitrogen compound transport GO:0071705 271 0.017
nucleocytoplasmic transport GO:0006913 139 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
response to peptide hormone GO:0043434 127 0.016
lateral inhibition GO:0046331 1 0.016
regulation of body fluid levels GO:0050878 162 0.016
lipid biosynthetic process GO:0008610 179 0.016
respiratory system development GO:0060541 190 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
male gamete generation GO:0048232 285 0.016
chemotaxis GO:0006935 247 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
skeletal muscle organ development GO:0060538 163 0.015
cell growth GO:0016049 130 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
transmission of nerve impulse GO:0019226 76 0.015
regulation of cell migration GO:0030334 219 0.015
negative regulation of cell development GO:0010721 169 0.015
immune effector process GO:0002252 321 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
methylation GO:0032259 134 0.015
organelle localization GO:0051640 179 0.015
regulation of protein kinase activity GO:0045859 232 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
cellular lipid metabolic process GO:0044255 323 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
regulation of proteolysis GO:0030162 164 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
single organism cell adhesion GO:0098602 156 0.013
positive regulation of endopeptidase activity GO:0010950 43 0.013
positive regulation of innate immune response GO:0045089 80 0.013
muscle tissue development GO:0060537 308 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
protein maturation GO:0051604 176 0.013
rna processing GO:0006396 105 0.013
small molecule biosynthetic process GO:0044283 132 0.013
regulation of anatomical structure size GO:0090066 178 0.013
nucleoside monophosphate catabolic process GO:0009125 59 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
heart morphogenesis GO:0003007 178 0.013
regulation of cellular component size GO:0032535 121 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
cellular response to lipid GO:0071396 145 0.013
positive regulation of cytoplasmic transport GO:1903651 40 0.012
multicellular organism growth GO:0035264 161 0.012
peptidyl lysine modification GO:0018205 77 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.012
response to light stimulus GO:0009416 135 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
body morphogenesis GO:0010171 45 0.012
histone acetylation GO:0016573 41 0.012
meiotic cell cycle GO:0051321 122 0.012
mrna metabolic process GO:0016071 84 0.012
cellular ketone metabolic process GO:0042180 84 0.012
anatomical structure homeostasis GO:0060249 145 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
adaptive immune response GO:0002250 155 0.012
placenta development GO:0001890 140 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
action potential GO:0001508 78 0.012
divalent inorganic cation transport GO:0072511 178 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of multi organism process GO:0043900 111 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
axon guidance GO:0007411 141 0.012
cellular response to acid chemical GO:0071229 68 0.011
tissue homeostasis GO:0001894 115 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
developmental cell growth GO:0048588 84 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of homeostatic process GO:0032844 182 0.011
positive regulation of growth GO:0045927 104 0.011
chromatin organization GO:0006325 206 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
neuron death GO:0070997 154 0.011
inflammatory response GO:0006954 244 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
lymphocyte proliferation GO:0046651 164 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
protein methylation GO:0006479 81 0.010
ribonucleoprotein complex subunit organization GO:0071826 28 0.010
ribonucleoprotein complex localization GO:0071166 1 0.010
cation transport GO:0006812 399 0.010
positive regulation of gtp catabolic process GO:0033126 85 0.010
regulation of cell size GO:0008361 72 0.010
wound healing GO:0042060 157 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
peptidyl amino acid modification GO:0018193 336 0.010
positive regulation of cell cycle g1 s phase transition GO:1902808 9 0.010
fatty acid metabolic process GO:0006631 121 0.010
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010

Tcp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.149
nervous system disease DOID:863 0 0.149
central nervous system disease DOID:331 0 0.021
retinal disease DOID:5679 0 0.016
retinal degeneration DOID:8466 0 0.016
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
neurodegenerative disease DOID:1289 0 0.013