Mus musculus

5 known processes

Duox1

dual oxidase 1

(Aliases: NOXEF1,NOXEF2,Duox2,AW987690,THOX2,LNOX1,LNOX2,THOX1,P138-TOX,9930101G15Rik)

Duox1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.171
amine metabolic process GO:0009308 45 0.138
transmembrane transport GO:0055085 412 0.100
cation transmembrane transport GO:0098655 266 0.076
cellular ketone metabolic process GO:0042180 84 0.075
negative regulation of cell proliferation GO:0008285 296 0.068
skin development GO:0043588 220 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.062
striated muscle tissue development GO:0014706 293 0.055
inorganic ion transmembrane transport GO:0098660 234 0.053
developmental maturation GO:0021700 193 0.050
regulation of cellular amine metabolic process GO:0033238 20 0.049
cytokine production GO:0001816 319 0.049
cellular lipid metabolic process GO:0044255 323 0.047
divalent metal ion transport GO:0070838 172 0.046
cellular amino acid metabolic process GO:0006520 103 0.046
cellular homeostasis GO:0019725 240 0.044
epidermis development GO:0008544 187 0.044
cation transport GO:0006812 399 0.043
ion transmembrane transport GO:0034220 361 0.043
gland development GO:0048732 330 0.042
hair cycle GO:0042633 90 0.039
muscle tissue development GO:0060537 308 0.038
immune effector process GO:0002252 321 0.038
apoptotic signaling pathway GO:0097190 306 0.038
cellular response to lipid GO:0071396 145 0.038
peptidyl amino acid modification GO:0018193 336 0.038
urogenital system development GO:0001655 261 0.037
ras protein signal transduction GO:0007265 77 0.036
response to lipopolysaccharide GO:0032496 128 0.036
positive regulation of interleukin 1 alpha production GO:0032730 4 0.036
cellular ion homeostasis GO:0006873 165 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
regulation of organelle organization GO:0033043 289 0.035
calcium ion transport GO:0006816 159 0.034
cation homeostasis GO:0055080 212 0.033
defense response to other organism GO:0098542 197 0.033
regulation of ion transmembrane transport GO:0034765 119 0.032
metal ion homeostasis GO:0055065 189 0.031
regulation of protein localization GO:0032880 231 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
extrinsic apoptotic signaling pathway GO:0097191 126 0.030
wound healing GO:0042060 157 0.029
engulfment of apoptotic cell GO:0043652 3 0.028
regulation of ion transport GO:0043269 215 0.028
defense response to bacterium GO:0042742 119 0.028
regulation of cell cycle GO:0051726 281 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
cellular chemical homeostasis GO:0055082 215 0.026
positive regulation of protein modification process GO:0031401 299 0.026
membrane organization GO:0061024 245 0.026
t cell activation GO:0042110 289 0.026
anion transport GO:0006820 177 0.025
divalent inorganic cation transport GO:0072511 178 0.025
negative regulation of molecular function GO:0044092 258 0.025
oxidation reduction process GO:0055114 342 0.025
skeletal muscle organ development GO:0060538 163 0.025
actin filament organization GO:0007015 113 0.024
response to extracellular stimulus GO:0009991 127 0.024
compound eye development GO:0048749 1 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
glycerolipid metabolic process GO:0046486 122 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
calcium ion transmembrane transport GO:0070588 85 0.023
muscle cell differentiation GO:0042692 261 0.022
hormone metabolic process GO:0042445 86 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
regulation of transferase activity GO:0051338 263 0.022
cytoplasmic transport GO:0016482 234 0.022
cellular response to organic cyclic compound GO:0071407 87 0.022
male gamete generation GO:0048232 285 0.022
sensory perception GO:0007600 245 0.022
camera type eye development GO:0043010 266 0.021
inflammatory response GO:0006954 244 0.021
regulation of anatomical structure size GO:0090066 178 0.021
muscle fiber development GO:0048747 76 0.021
epithelial cell development GO:0002064 159 0.021
sequestering of calcium ion GO:0051208 18 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
sensory organ morphogenesis GO:0090596 242 0.021
multicellular organism growth GO:0035264 161 0.021
negative regulation of lymphocyte activation GO:0051250 91 0.021
organic acid transport GO:0015849 101 0.020
regulation of metal ion transport GO:0010959 106 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
cell maturation GO:0048469 127 0.020
regulation of transmembrane transport GO:0034762 128 0.020
regulation of kinase activity GO:0043549 249 0.020
spermatogenesis GO:0007283 284 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
regulation of calcium ion transport GO:0051924 69 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
regulation of protein transport GO:0051223 163 0.020
aromatic compound catabolic process GO:0019439 286 0.020
purine nucleotide metabolic process GO:0006163 302 0.019
nitrogen compound transport GO:0071705 271 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
kidney development GO:0001822 213 0.019
peptidyl serine modification GO:0018209 83 0.019
regulation of secretion GO:0051046 274 0.019
sequestering of metal ion GO:0051238 19 0.018
peptidyl serine phosphorylation GO:0018105 74 0.018
protein processing GO:0016485 163 0.018
negative regulation of cell development GO:0010721 169 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
regulation of cytokine production GO:0001817 266 0.018
leukocyte differentiation GO:0002521 342 0.018
actin cytoskeleton organization GO:0030036 220 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
intracellular protein transport GO:0006886 204 0.017
ear development GO:0043583 200 0.017
carboxylic acid transport GO:0046942 100 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
lens development in camera type eye GO:0002088 62 0.017
digestive system development GO:0055123 200 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
neural tube development GO:0021915 160 0.017
positive regulation of secretion GO:0051047 130 0.017
cell type specific apoptotic process GO:0097285 268 0.017
regulation of hormone levels GO:0010817 211 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
microtubule based process GO:0007017 236 0.017
response to growth factor GO:0070848 198 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.016
positive regulation of cytokine production GO:0001819 174 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
negative regulation of immune system process GO:0002683 209 0.016
regulation of myotube differentiation GO:0010830 62 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
regulation of cellular component size GO:0032535 121 0.016
amide transport GO:0042886 138 0.016
regionalization GO:0003002 337 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.015
cell activation involved in immune response GO:0002263 126 0.015
response to organic cyclic compound GO:0014070 198 0.015
Human
single organism cell adhesion GO:0098602 156 0.015
alcohol metabolic process GO:0006066 116 0.015
purine containing compound metabolic process GO:0072521 311 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of body fluid levels GO:0050878 162 0.015
mapk cascade GO:0000165 281 0.015
placenta development GO:0001890 140 0.015
regulation of hydrolase activity GO:0051336 246 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
regulation of stem cell proliferation GO:0072091 78 0.015
myeloid cell differentiation GO:0030099 233 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
protein maturation GO:0051604 176 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
sodium ion transport GO:0006814 73 0.014
regulation of secretion by cell GO:1903530 249 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
maintenance of location GO:0051235 89 0.014
small molecule biosynthetic process GO:0044283 132 0.014
negative regulation of cell activation GO:0050866 111 0.014
regulation of proteolysis GO:0030162 164 0.014
organophosphate catabolic process GO:0046434 232 0.014
skeletal system development GO:0001501 356 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
rhythmic process GO:0048511 174 0.014
striated muscle cell development GO:0055002 125 0.014
nuclear transport GO:0051169 139 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
heterocycle catabolic process GO:0046700 280 0.014
blood circulation GO:0008015 195 0.014
ossification GO:0001503 216 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
positive regulation of ion transport GO:0043270 65 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
carbohydrate metabolic process GO:0005975 230 0.013
organelle fission GO:0048285 170 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
carbohydrate homeostasis GO:0033500 128 0.013
regulation of cell cycle process GO:0010564 160 0.013
stem cell proliferation GO:0072089 117 0.013
hair cell differentiation GO:0035315 40 0.013
adult behavior GO:0030534 135 0.013
organic anion transport GO:0015711 137 0.013
epithelial cell proliferation GO:0050673 174 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
adaptive immune response GO:0002250 155 0.013
cardiac chamber development GO:0003205 108 0.013
cell adhesion GO:0007155 329 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
organelle localization GO:0051640 179 0.013
hypotonic response GO:0006971 3 0.013
stem cell differentiation GO:0048863 268 0.013
nephron tubule development GO:0072080 84 0.013
glucose homeostasis GO:0042593 128 0.013
detection of stimulus GO:0051606 84 0.013
positive regulation of nervous system development GO:0051962 221 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
multi multicellular organism process GO:0044706 109 0.013
regulation of protein secretion GO:0050708 82 0.013
cellular response to peptide GO:1901653 92 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of system process GO:0044057 200 0.012
response to starvation GO:0042594 65 0.012
calcium ion homeostasis GO:0055074 127 0.012
monocarboxylic acid transport GO:0015718 44 0.012
lymphocyte differentiation GO:0030098 242 0.012
leukocyte migration GO:0050900 124 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
amino acid betaine transport GO:0015838 3 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
somatotropin secreting cell differentiation GO:0060126 4 0.012
tube formation GO:0035148 140 0.012
protein localization to membrane GO:0072657 108 0.012
fat soluble vitamin biosynthetic process GO:0042362 4 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
axonogenesis GO:0007409 274 0.012
endocytosis GO:0006897 168 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
regulation of cell activation GO:0050865 289 0.012
memory GO:0007613 58 0.012
response to osmotic stress GO:0006970 21 0.012
skeletal muscle fiber development GO:0048741 58 0.012
regulation of defense response GO:0031347 233 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.012
regulation of binding GO:0051098 111 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
organic hydroxy compound transport GO:0015850 93 0.012
mitotic cell cycle GO:0000278 195 0.011
fat cell differentiation GO:0045444 160 0.011
response to nutrient levels GO:0031667 109 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
blood vessel morphogenesis GO:0048514 285 0.011
myotube cell development GO:0014904 60 0.011
regulation of engulfment of apoptotic cell GO:1901074 2 0.011
regulation of interleukin 1 alpha production GO:0032650 4 0.011
nucleotide metabolic process GO:0009117 332 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
respiratory system development GO:0060541 190 0.011
nuclear division GO:0000280 158 0.011
lipid biosynthetic process GO:0008610 179 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
hexose metabolic process GO:0019318 98 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
response to insulin GO:0032868 100 0.011
chromatin organization GO:0006325 206 0.011
development of primary sexual characteristics GO:0045137 143 0.011
fluid transport GO:0042044 14 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
molting cycle GO:0042303 90 0.011
organ growth GO:0035265 117 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
negative regulation of t cell activation GO:0050868 65 0.011
germ cell development GO:0007281 185 0.011
endomembrane system organization GO:0010256 147 0.011
sphingolipid metabolic process GO:0006665 45 0.011
peptide transport GO:0015833 133 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
heart morphogenesis GO:0003007 178 0.011
hair follicle development GO:0001942 85 0.011
renal system development GO:0072001 225 0.011
regulation of response to wounding GO:1903034 189 0.011
wnt signaling pathway GO:0016055 188 0.011
positive regulation of cell development GO:0010720 237 0.011
forebrain development GO:0030900 302 0.011
regulation of intracellular transport GO:0032386 159 0.011
protein polymerization GO:0051258 57 0.011
regulation of homeostatic process GO:0032844 182 0.011
blastocyst development GO:0001824 80 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
regulation of defense response to bacterium GO:1900424 3 0.011
positive regulation of stem cell proliferation GO:2000648 59 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
stem cell development GO:0048864 219 0.011
positive regulation of cell death GO:0010942 224 0.011
negative regulation of nervous system development GO:0051961 156 0.011
response to organonitrogen compound GO:0010243 246 0.011
Human
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
rho protein signal transduction GO:0007266 32 0.010
regulation of peptide transport GO:0090087 91 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
response to peptide GO:1901652 136 0.010
cellular protein complex assembly GO:0043623 116 0.010
response to metal ion GO:0010038 47 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
lung development GO:0030324 164 0.010
chromatin modification GO:0016568 187 0.010
regulation of cell migration GO:0030334 219 0.010
dna metabolic process GO:0006259 303 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
leukocyte proliferation GO:0070661 172 0.010
regulation of response to osmotic stress GO:0047484 3 0.010
response to oxygen levels GO:0070482 62 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
establishment of blood nerve barrier GO:0008065 3 0.010
nucleoside metabolic process GO:0009116 246 0.010
ceramide biosynthetic process GO:0046513 20 0.010
developmental cell growth GO:0048588 84 0.010

Duox1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
disease of cellular proliferation DOID:14566 0 0.012