Mus musculus

69 known processes

Duox2

dual oxidase 2

(Aliases: NOXEF2,P138-TOX,THOX2,A430065P05Rik,LNOX2)

Duox2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.942
regulation of defense response GO:0031347 233 0.725
regulation of female receptivity GO:0045924 6 0.694
thyroid hormone metabolic process GO:0042403 16 0.686
osteoclast differentiation GO:0030316 62 0.680
activation of adenylate cyclase activity GO:0007190 4 0.652
regulation of cellular amine metabolic process GO:0033238 20 0.636
retinal cone cell differentiation GO:0042670 8 0.593
retinal cone cell development GO:0046549 8 0.581
reactive oxygen species biosynthetic process GO:1903409 8 0.577
Zebrafish
myeloid leukocyte differentiation GO:0002573 119 0.576
type i pneumocyte differentiation GO:0060509 7 0.569
amine metabolic process GO:0009308 45 0.564
regulation of myeloid leukocyte differentiation GO:0002761 58 0.551
lipid biosynthetic process GO:0008610 179 0.540
ovarian follicle development GO:0001541 40 0.539
negative regulation of cytokine production GO:0001818 84 0.538
regulation of membrane potential GO:0042391 192 0.508
epithelial tube morphogenesis GO:0060562 303 0.492
negative regulation of interleukin 5 production GO:0032714 4 0.471
positive regulation of camp metabolic process GO:0030816 19 0.470
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.459
kidney development GO:0001822 213 0.456
cellular modified amino acid metabolic process GO:0006575 63 0.447
cellular amino acid metabolic process GO:0006520 103 0.441
regulation of cytokine production GO:0001817 266 0.430
cellular response to nitric oxide GO:0071732 4 0.421
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.417
spermatogenesis GO:0007283 284 0.416
sertoli cell differentiation GO:0060008 18 0.398
cellular amine metabolic process GO:0044106 44 0.395
oxidation reduction process GO:0055114 342 0.391
Worm
nephron epithelium morphogenesis GO:0072088 68 0.390
extracellular matrix organization GO:0030198 147 0.385
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.383
synaptic transmission GO:0007268 329 0.380
morphogenesis of a branching epithelium GO:0061138 193 0.376
toll like receptor signaling pathway GO:0002224 38 0.375
small molecule biosynthetic process GO:0044283 132 0.368
regulation of neurotransmitter levels GO:0001505 87 0.360
epithelial cell proliferation GO:0050673 174 0.357
regulation of myeloid cell differentiation GO:0045637 96 0.342
embryonic organ morphogenesis GO:0048562 276 0.338
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.337
immune response activating signal transduction GO:0002757 116 0.333
immune response regulating signaling pathway GO:0002764 125 0.332
extracellular structure organization GO:0043062 148 0.327
mesonephric epithelium development GO:0072163 94 0.323
acetylcholine secretion neurotransmission GO:0014055 2 0.320
urogenital system development GO:0001655 261 0.320
chondroblast differentiation GO:0060591 2 0.316
multicellular organism growth GO:0035264 161 0.311
response to oxidative stress GO:0006979 123 0.309
Worm
regulation of steroid biosynthetic process GO:0050810 26 0.308
female sex differentiation GO:0046660 84 0.299
development of primary male sexual characteristics GO:0046546 88 0.299
germ cell development GO:0007281 185 0.296
activation of immune response GO:0002253 138 0.294
protein dna complex subunit organization GO:0071824 28 0.292
regulation of camp biosynthetic process GO:0030817 25 0.292
phenol containing compound metabolic process GO:0018958 60 0.291
negative regulation of multi organism process GO:0043901 68 0.289
renal system development GO:0072001 225 0.287
epithelial cell development GO:0002064 159 0.282
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.282
negative regulation of translational initiation GO:0045947 4 0.281
positive regulation of defense response GO:0031349 124 0.280
cellular water homeostasis GO:0009992 2 0.280
protein catabolic process GO:0030163 221 0.280
positive regulation of innate immune response GO:0045089 80 0.279
bone mineralization GO:0030282 54 0.278
positive regulation of camp biosynthetic process GO:0030819 19 0.270
defense response to other organism GO:0098542 197 0.269
Zebrafish
regulation of multi organism process GO:0043900 111 0.268
cellular macromolecule catabolic process GO:0044265 206 0.264
reactive oxygen species metabolic process GO:0072593 84 0.264
Zebrafish
methylation GO:0032259 134 0.262
cellular homeostasis GO:0019725 240 0.256
regulation of secretion by cell GO:1903530 249 0.256
regulation of camp metabolic process GO:0030814 30 0.255
sensory organ morphogenesis GO:0090596 242 0.254
male sex differentiation GO:0046661 109 0.254
steroid biosynthetic process GO:0006694 47 0.252
g protein coupled receptor signaling pathway GO:0007186 243 0.252
negative regulation of female receptivity GO:0007621 2 0.251
regulation of feeding behavior GO:0060259 3 0.248
regulation of homeostatic process GO:0032844 182 0.248
response to molecule of bacterial origin GO:0002237 143 0.247
cytokine production GO:0001816 319 0.240
camp metabolic process GO:0046058 40 0.238
regulation of leukocyte differentiation GO:1902105 159 0.235
lymphocyte differentiation GO:0030098 242 0.234
mechanoreceptor differentiation GO:0042490 67 0.233
cellular response to gonadotropin stimulus GO:0071371 4 0.231
purine ribonucleotide metabolic process GO:0009150 290 0.231
organic hydroxy compound biosynthetic process GO:1901617 77 0.230
steroid metabolic process GO:0008202 119 0.230
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.225
cholesterol homeostasis GO:0042632 44 0.225
chromatin organization GO:0006325 206 0.224
ureteric bud development GO:0001657 94 0.223
circulatory system process GO:0003013 197 0.222
response to nitric oxide GO:0071731 4 0.222
mesonephric tubule development GO:0072164 94 0.222
cation transport GO:0006812 399 0.221
leukocyte migration GO:0050900 124 0.220
Zebrafish
carbohydrate derivative biosynthetic process GO:1901137 183 0.219
regulation of lipid metabolic process GO:0019216 118 0.218
regulation of mapk cascade GO:0043408 248 0.216
inositol trisphosphate metabolic process GO:0032957 5 0.216
cell differentiation involved in metanephros development GO:0072202 12 0.216
regulation of thyroid hormone generation GO:2000609 4 0.212
ribose phosphate biosynthetic process GO:0046390 59 0.207
male gamete generation GO:0048232 285 0.207
metanephric epithelium development GO:0072207 21 0.204
response to leptin GO:0044321 7 0.203
nitrogen compound transport GO:0071705 271 0.202
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.201
proteasomal protein catabolic process GO:0010498 98 0.198
camera type eye development GO:0043010 266 0.194
regulation of phospholipase c activity GO:1900274 3 0.194
acetylcholine transport GO:0015870 2 0.193
growth of symbiont involved in interaction with host GO:0044116 23 0.192
cellular carbohydrate metabolic process GO:0044262 119 0.190
regulation of steroid metabolic process GO:0019218 39 0.189
leukocyte differentiation GO:0002521 342 0.188
canonical wnt signaling pathway GO:0060070 130 0.188
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.186
interspecies interaction between organisms GO:0044419 83 0.185
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.185
inflammatory response GO:0006954 244 0.184
Zebrafish
organic hydroxy compound metabolic process GO:1901615 203 0.184
female courtship behavior GO:0008050 3 0.184
harderian gland development GO:0070384 2 0.183
regulation of protein transport GO:0051223 163 0.182
ureteric bud morphogenesis GO:0060675 62 0.182
lung development GO:0030324 164 0.181
sensory perception of sound GO:0007605 97 0.177
tube closure GO:0060606 91 0.174
sensory perception of umami taste GO:0050917 4 0.172
intracellular receptor signaling pathway GO:0030522 74 0.172
metanephric nephron morphogenesis GO:0072273 19 0.171
limb development GO:0060173 166 0.170
inner ear receptor stereocilium organization GO:0060122 23 0.169
gland development GO:0048732 330 0.168
positive regulation of phospholipase activity GO:0010518 3 0.168
cellular response to biotic stimulus GO:0071216 92 0.168
metanephric glomerulus development GO:0072224 13 0.166
innate immune response GO:0045087 157 0.166
innate immune response activating signal transduction GO:0002758 50 0.166
erythrocyte differentiation GO:0030218 88 0.165
circadian temperature homeostasis GO:0060086 2 0.164
adult locomotory behavior GO:0008344 91 0.162
regulation of osteoclast differentiation GO:0045670 36 0.162
inner ear receptor cell development GO:0060119 39 0.160
lipid homeostasis GO:0055088 63 0.160
thyroid hormone mediated signaling pathway GO:0002154 3 0.160
immune effector process GO:0002252 321 0.159
mapk cascade GO:0000165 281 0.157
renal tubule development GO:0061326 87 0.155
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.154
inner ear receptor cell differentiation GO:0060113 61 0.153
nucleobase containing small molecule metabolic process GO:0055086 352 0.151
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.150
mesonephros development GO:0001823 97 0.149
water homeostasis GO:0030104 27 0.148
adult behavior GO:0030534 135 0.148
cellular response to lipopolysaccharide GO:0071222 77 0.147
myeloid leukocyte migration GO:0097529 57 0.147
activation of innate immune response GO:0002218 56 0.145
lacrimal gland development GO:0032808 5 0.144
regulation of inflammatory response GO:0050727 147 0.144
b cell activation GO:0042113 161 0.143
regulation of nucleotide metabolic process GO:0006140 169 0.143
nephron morphogenesis GO:0072028 69 0.143
growth involved in symbiotic interaction GO:0044110 23 0.143
cellular response to reactive nitrogen species GO:1902170 5 0.142
macromolecule methylation GO:0043414 120 0.141
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.141
regulation of cellular amino acid metabolic process GO:0006521 5 0.141
regulation of organ morphogenesis GO:2000027 144 0.138
respiratory burst GO:0045730 8 0.137
muscle cell differentiation GO:0042692 261 0.137
positive regulation of intracellular steroid hormone receptor signaling pathway GO:0033145 4 0.136
ion transmembrane transport GO:0034220 361 0.135
chromatin modification GO:0016568 187 0.134
regulation of hormone levels GO:0010817 211 0.134
b cell differentiation GO:0030183 78 0.133
sterol homeostasis GO:0055092 45 0.132
basement membrane organization GO:0071711 8 0.132
interleukin 4 production GO:0032633 24 0.131
gonad development GO:0008406 141 0.131
spermatid development GO:0007286 108 0.131
regulation of cyclase activity GO:0031279 13 0.130
carbohydrate metabolic process GO:0005975 230 0.129
organonitrogen compound biosynthetic process GO:1901566 192 0.129
ribonucleotide metabolic process GO:0009259 291 0.129
appendage development GO:0048736 166 0.127
negative regulation of protein transport GO:0051224 46 0.126
regulation of innate immune response GO:0045088 91 0.126
nephron tubule morphogenesis GO:0072078 68 0.125
sensory perception GO:0007600 245 0.124
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.123
macromolecule catabolic process GO:0009057 281 0.122
hydrogen peroxide metabolic process GO:0042743 16 0.121
Zebrafish
organic acid biosynthetic process GO:0016053 86 0.121
limb morphogenesis GO:0035108 149 0.120
regulation of toll like receptor signaling pathway GO:0034121 20 0.120
positive regulation of steroid biosynthetic process GO:0010893 4 0.120
cellular response to oxidative stress GO:0034599 76 0.120
purine ribonucleotide biosynthetic process GO:0009152 59 0.119
retina development in camera type eye GO:0060041 119 0.117
pattern recognition receptor signaling pathway GO:0002221 47 0.116
cellular chemical homeostasis GO:0055082 215 0.114
multicellular organismal homeostasis GO:0048871 164 0.112
acetate ester transport GO:1901374 2 0.112
platelet activation GO:0030168 40 0.112
camp biosynthetic process GO:0006171 31 0.112
female mating behavior GO:0060180 8 0.111
granulocyte migration GO:0097530 43 0.110
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.110
glomerulus development GO:0032835 40 0.110
carboxylic acid biosynthetic process GO:0046394 86 0.110
cellular response to molecule of bacterial origin GO:0071219 83 0.110
type b pancreatic cell proliferation GO:0044342 10 0.109
glycogen biosynthetic process GO:0005978 14 0.109
appendage morphogenesis GO:0035107 149 0.109
negative regulation of immune system process GO:0002683 209 0.109
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.109
multicellular organismal signaling GO:0035637 91 0.108
genetic imprinting GO:0071514 27 0.108
cellular ketone metabolic process GO:0042180 84 0.108
biomineral tissue development GO:0031214 64 0.107
response to ph GO:0009268 14 0.107
skeletal system morphogenesis GO:0048705 203 0.105
thyroid hormone generation GO:0006590 7 0.104
positive regulation of nucleotide metabolic process GO:0045981 114 0.104
anion transport GO:0006820 177 0.104
cellular protein catabolic process GO:0044257 155 0.104
nucleoside phosphate biosynthetic process GO:1901293 79 0.104
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.103
regulation of cholesterol homeostasis GO:2000188 9 0.102
purine containing compound metabolic process GO:0072521 311 0.102
regulation of purine nucleotide metabolic process GO:1900542 169 0.102
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.100
regulation of growth of symbiont in host GO:0044126 19 0.100
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.100
kidney morphogenesis GO:0060993 83 0.100
cyclic nucleotide metabolic process GO:0009187 59 0.099
transmission of nerve impulse GO:0019226 76 0.099
myeloid cell homeostasis GO:0002262 114 0.099
growth of symbiont in host GO:0044117 23 0.097
regulation of protein complex assembly GO:0043254 83 0.097
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.097
response to superoxide GO:0000303 16 0.097
courtship behavior GO:0007619 5 0.096
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.096
spermatid nucleus differentiation GO:0007289 19 0.096
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.094
wnt signaling pathway involved in kidney development GO:0061289 2 0.093
purine nucleotide biosynthetic process GO:0006164 65 0.092
action potential GO:0001508 78 0.092
negative regulation of translation GO:0017148 22 0.090
response to inorganic substance GO:0010035 96 0.089
carbon catabolite activation of transcription GO:0045991 4 0.088
regulation of hormone metabolic process GO:0032350 15 0.088
cellular response to acid chemical GO:0071229 68 0.087
ovulation cycle GO:0042698 59 0.087
cellular response to hormone stimulus GO:0032870 150 0.086
dna methylation GO:0006306 43 0.086
response to lipopolysaccharide GO:0032496 128 0.086
blood circulation GO:0008015 195 0.085
skeletal system development GO:0001501 356 0.085
positive regulation of lipid metabolic process GO:0045834 40 0.085
embryonic epithelial tube formation GO:0001838 130 0.085
regulation of intracellular transport GO:0032386 159 0.084
ribose phosphate metabolic process GO:0019693 291 0.084
seminiferous tubule development GO:0072520 14 0.084
organic anion transport GO:0015711 137 0.083
metanephric nephron epithelium development GO:0072243 19 0.083
cellular response to inorganic substance GO:0071241 37 0.082
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.081
endocrine system development GO:0035270 98 0.081
regulation of response to wounding GO:1903034 189 0.080
positive regulation of camp mediated signaling GO:0043950 3 0.080
regulation of blood pressure GO:0008217 93 0.079
endochondral bone morphogenesis GO:0060350 50 0.079
regulation of cellular response to stress GO:0080135 159 0.079
regulation of canonical wnt signaling pathway GO:0060828 82 0.077
regulation of systemic arterial blood pressure GO:0003073 61 0.076
regulation of organelle organization GO:0033043 289 0.076
neural tube development GO:0021915 160 0.075
positive regulation of phospholipase c activity GO:0010863 2 0.075
nucleotide biosynthetic process GO:0009165 78 0.075
metanephric nephron development GO:0072210 34 0.075
regulation of translation GO:0006417 71 0.075
eye photoreceptor cell development GO:0042462 31 0.074
positive regulation of lipid biosynthetic process GO:0046889 18 0.073
regulation of nucleotide biosynthetic process GO:0030808 34 0.072
fat cell differentiation GO:0045444 160 0.072
granulocyte differentiation GO:0030851 17 0.072
response to reactive oxygen species GO:0000302 56 0.072
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.072
inorganic ion transmembrane transport GO:0098660 234 0.071
regulation of adenylate cyclase activity GO:0045761 10 0.071
regulation of system process GO:0044057 200 0.071
renal tubule morphogenesis GO:0061333 72 0.071
purine containing compound biosynthetic process GO:0072522 70 0.071
monocarboxylic acid metabolic process GO:0032787 191 0.071
glandular epithelial cell development GO:0002068 15 0.070
camera type eye photoreceptor cell differentiation GO:0060219 15 0.070
cellular lipid metabolic process GO:0044255 323 0.070
positive regulation of metanephric glomerulus development GO:0072300 4 0.070
organophosphate biosynthetic process GO:0090407 122 0.070
regulation of bone remodeling GO:0046850 28 0.070
regulation of chromosome organization GO:0033044 83 0.069
myeloid cell differentiation GO:0030099 233 0.069
ossification GO:0001503 216 0.069
ear morphogenesis GO:0042471 118 0.069
cation homeostasis GO:0055080 212 0.069
photoreceptor cell differentiation GO:0046530 52 0.069
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.069
ribonucleotide biosynthetic process GO:0009260 59 0.068
posttranscriptional regulation of gene expression GO:0010608 155 0.068
regulation of lyase activity GO:0051339 13 0.068
lung epithelium development GO:0060428 37 0.068
superoxide metabolic process GO:0006801 27 0.067
nucleotide metabolic process GO:0009117 332 0.067
positive regulation of cellular amine metabolic process GO:0033240 5 0.067
regulation of muscle tissue development GO:1901861 97 0.066
glandular epithelial cell differentiation GO:0002067 38 0.066
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.065
regulation of myotube differentiation GO:0010830 62 0.065
cell type specific apoptotic process GO:0097285 268 0.065
regulation of lipid biosynthetic process GO:0046890 54 0.065
peptidyl amino acid modification GO:0018193 336 0.064
negative regulation of intracellular signal transduction GO:1902532 167 0.064
regulation of cell motility GO:2000145 236 0.064
cellular response to superoxide GO:0071451 14 0.064
lung cell differentiation GO:0060479 30 0.064
organic acid transport GO:0015849 101 0.064
morphogenesis of a branching structure GO:0001763 203 0.064
kidney epithelium development GO:0072073 121 0.063
regulation of osteoblast differentiation GO:0045667 67 0.063
regulation of cytokine secretion GO:0050707 61 0.063
negative regulation of protein secretion GO:0050709 20 0.063
dna metabolic process GO:0006259 303 0.063
regulation of cell projection organization GO:0031344 206 0.062
energy derivation by oxidation of organic compounds GO:0015980 77 0.062
anatomical structure homeostasis GO:0060249 145 0.062
regulation of establishment of protein localization GO:0070201 181 0.061
cytoplasmic sequestering of transcription factor GO:0042994 5 0.061
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.061
homeostasis of number of cells GO:0048872 210 0.061
bone morphogenesis GO:0060349 78 0.061
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.060
positive regulation of wnt signaling pathway GO:0030177 45 0.060
alcohol biosynthetic process GO:0046165 43 0.060
maintenance of location GO:0051235 89 0.060
purine nucleotide metabolic process GO:0006163 302 0.060
heart contraction GO:0060047 93 0.060
positive regulation of kidney development GO:0090184 28 0.060
placenta development GO:0001890 140 0.059
chondrocyte development GO:0002063 24 0.059
nucleoside phosphate metabolic process GO:0006753 338 0.059
protein methylation GO:0006479 81 0.059
positive regulation of hormone metabolic process GO:0032352 3 0.058
heart process GO:0003015 94 0.058
defense response to nematode GO:0002215 4 0.058
metanephric tubule development GO:0072170 18 0.057
tube formation GO:0035148 140 0.057
response to cold GO:0009409 19 0.056
lung epithelial cell differentiation GO:0060487 29 0.056
nephron development GO:0072006 109 0.056
generation of precursor metabolites and energy GO:0006091 103 0.055
carbon catabolite regulation of transcription GO:0045990 4 0.055
prostate gland development GO:0030850 48 0.055
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.055
development of primary sexual characteristics GO:0045137 143 0.055
central nervous system neuron differentiation GO:0021953 162 0.055
cyclic purine nucleotide metabolic process GO:0052652 43 0.055
growth plate cartilage development GO:0003417 14 0.054
embryonic limb morphogenesis GO:0030326 126 0.054
hydrogen peroxide catabolic process GO:0042744 5 0.054
cartilage condensation GO:0001502 18 0.054
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.053
polysaccharide biosynthetic process GO:0000271 20 0.053
hormone biosynthetic process GO:0042446 16 0.053
removal of superoxide radicals GO:0019430 12 0.053
dna conformation change GO:0071103 37 0.053
sensory perception of mechanical stimulus GO:0050954 107 0.053
response to oxygen radical GO:0000305 16 0.052
cellular response to oxygen radical GO:0071450 14 0.052
liver development GO:0001889 66 0.052
regulation of lipase activity GO:0060191 15 0.052
regulation of intracellular protein transport GO:0033157 82 0.051
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.051
second messenger mediated signaling GO:0019932 73 0.051
male gonad development GO:0008584 88 0.051
regulation of transferase activity GO:0051338 263 0.051
sensory perception of taste GO:0050909 18 0.051
sertoli cell development GO:0060009 15 0.051
regulation of cellular catabolic process GO:0031329 242 0.050
cellular response to hexose stimulus GO:0071331 47 0.050
growth plate cartilage chondrocyte development GO:0003431 3 0.050
anatomical structure maturation GO:0071695 49 0.050
spermatid differentiation GO:0048515 115 0.050
cellular polysaccharide metabolic process GO:0044264 38 0.050
t cell activation GO:0042110 289 0.050
polyol metabolic process GO:0019751 26 0.049
metanephric nephron tubule development GO:0072234 16 0.049
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.049
negative regulation of cellular component organization GO:0051129 194 0.049
energy reserve metabolic process GO:0006112 39 0.049
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.049
negative regulation of growth of symbiont in host GO:0044130 19 0.049
tissue homeostasis GO:0001894 115 0.049
regulation of nucleocytoplasmic transport GO:0046822 73 0.049
positive regulation of ion transport GO:0043270 65 0.049
leukocyte activation involved in immune response GO:0002366 126 0.049
clara cell differentiation GO:0060486 4 0.049
acetylcholine metabolic process GO:0008291 3 0.049
regulation of fat cell differentiation GO:0045598 81 0.048
skin development GO:0043588 220 0.048
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.048
regulation of cellular protein catabolic process GO:1903362 61 0.048
negative regulation of protein metabolic process GO:0051248 282 0.048
positive regulation of nervous system development GO:0051962 221 0.047
eosinophil migration GO:0072677 3 0.047
response to hydrogen peroxide GO:0042542 32 0.047
lipid catabolic process GO:0016042 69 0.047
blood coagulation GO:0007596 76 0.047
cellular response to extracellular stimulus GO:0031668 81 0.047
ensheathment of neurons GO:0007272 76 0.046
response to nutrient levels GO:0031667 109 0.046
positive regulation of thyroid hormone generation GO:2000611 2 0.046
negative regulation of apoptotic signaling pathway GO:2001234 104 0.046
transmembrane transport GO:0055085 412 0.046
cellular response to glucose stimulus GO:0071333 45 0.045
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.045
rhythmic process GO:0048511 174 0.045
respiratory system development GO:0060541 190 0.045
chondrocyte hypertrophy GO:0003415 4 0.045
neural tube closure GO:0001843 90 0.044
wnt signaling pathway GO:0016055 188 0.044
neural retina development GO:0003407 41 0.044
rhodopsin mediated signaling pathway GO:0016056 4 0.044
ear development GO:0043583 200 0.044
hemostasis GO:0007599 78 0.044
small gtpase mediated signal transduction GO:0007264 97 0.044
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.044
positive regulation of osteoblast differentiation GO:0045669 34 0.044
regulation of steroid hormone biosynthetic process GO:0090030 4 0.043
hepaticobiliary system development GO:0061008 67 0.043
developmental cell growth GO:0048588 84 0.043
ubiquitin dependent protein catabolic process GO:0006511 129 0.043
engulfment of apoptotic cell GO:0043652 3 0.042
bone development GO:0060348 120 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
regulation of energy homeostasis GO:2000505 7 0.042
organonitrogen compound catabolic process GO:1901565 264 0.042
sulfur compound metabolic process GO:0006790 100 0.042
muscle tissue development GO:0060537 308 0.042
positive regulation of cytokine production GO:0001819 174 0.042
cartilage development GO:0051216 140 0.041
wound healing GO:0042060 157 0.041
cochlea development GO:0090102 35 0.041
cellular response to radiation GO:0071478 28 0.040
amino acid transport GO:0006865 61 0.040
sensory perception of chemical stimulus GO:0007606 51 0.040
heart morphogenesis GO:0003007 178 0.040
cardiac chamber morphogenesis GO:0003206 93 0.040
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.039
cellular polysaccharide biosynthetic process GO:0033692 19 0.039
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.039
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.039
dna modification GO:0006304 50 0.039
regulation of neuron differentiation GO:0045664 281 0.039
neurotransmitter transport GO:0006836 76 0.039
regulation of kidney size GO:0035564 3 0.039
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.038
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.038
cell cell signaling involved in kidney development GO:0060995 2 0.038
hormone metabolic process GO:0042445 86 0.038
establishment of protein localization to organelle GO:0072594 118 0.038
regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 31 0.038
alcohol metabolic process GO:0006066 116 0.038
cell differentiation involved in kidney development GO:0061005 33 0.038
regulation of organ growth GO:0046620 61 0.038
photoreceptor cell development GO:0042461 40 0.038
response to acid chemical GO:0001101 111 0.037
learning or memory GO:0007611 148 0.037
negative regulation of bone remodeling GO:0046851 6 0.037
skeletal muscle cell differentiation GO:0035914 66 0.037

Duox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
thyroid gland disease DOID:50 0 0.945
hypothyroidism DOID:1459 0 0.945
disease of anatomical entity DOID:7 0 0.945
endocrine system disease DOID:28 0 0.945
congenital hypothyroidism DOID:0050328 0 0.094