|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.893
|
Worm |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.893
|
Worm |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.836
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.836
|
Fly |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.749
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.683
|
Worm |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.683
|
Worm |
|
|
t cell activation
|
GO:0042110 |
289 |
0.619
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.617
|
Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.614
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.587
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.572
|
Worm |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.570
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.562
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.525
|
Zebrafish Mouse Worm Fly |
|
|
cell junction organization
|
GO:0034330 |
77 |
0.518
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.517
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.513
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.493
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.466
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.462
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.440
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.420
|
Mouse |
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.420
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.410
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.394
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.388
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.384
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.382
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.378
|
Worm |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.374
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.374
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.373
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.371
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.371
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.369
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.360
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.352
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.352
|
Mouse Worm |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.352
|
Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.352
|
Human |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.351
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.345
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.336
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.334
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.334
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.329
|
Worm |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.327
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.324
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.322
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.317
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.316
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.315
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.305
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.302
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.301
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.299
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.291
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.289
|
Worm |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.289
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.288
|
Human |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.285
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.284
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.279
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.276
|
Mouse Worm Fly |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.274
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.273
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.269
|
Mouse |
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.263
|
Fly |
|
|
regionalization
|
GO:0003002 |
337 |
0.262
|
Mouse Worm Fly |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.261
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.257
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.256
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.255
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.255
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.252
|
Mouse Worm |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.245
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.244
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.243
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.242
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.241
|
Mouse |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.236
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.236
|
Human Worm |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.233
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.233
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.231
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.229
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.226
|
Worm |
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.225
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.221
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.220
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.218
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.214
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.214
|
Mouse |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.210
|
Mouse |
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.209
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.208
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.207
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.205
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.204
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.201
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.198
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.197
|
Mouse Fly |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.196
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.193
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.192
|
Mouse |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.191
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.190
|
Mouse Worm Fly |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.186
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.185
|
Mouse |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.183
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.183
|
Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.177
|
Mouse |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.174
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.173
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.173
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.172
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.172
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.170
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.170
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.169
|
Mouse Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.167
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.167
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.166
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.165
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.160
|
Human |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.158
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.156
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.154
|
Human |
|
|
hindbrain development
|
GO:0030902 |
128 |
0.154
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.152
|
Mouse |
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.151
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.150
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.148
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.148
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.146
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
165 |
0.146
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.145
|
Human |
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.145
|
|
|
|
ventricular cardiac muscle cell action potential
|
GO:0086005 |
4 |
0.144
|
Human |
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.143
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.141
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.141
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.140
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.137
|
|
|
|
cardiac muscle fiber development
|
GO:0048739 |
4 |
0.137
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.134
|
Human Worm |
|
|
telencephalon development
|
GO:0021537 |
186 |
0.133
|
Mouse |
|
|
regulation of endothelial cell migration
|
GO:0010594 |
22 |
0.132
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.129
|
Mouse |
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.125
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.125
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.125
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.125
|
Mouse Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.124
|
Mouse |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.124
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.123
|
Mouse Worm Fly |
|
|
protein targeting
|
GO:0006605 |
143 |
0.123
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.122
|
Worm |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.122
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.121
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.121
|
Worm |
|
|
membrane organization
|
GO:0061024 |
245 |
0.118
|
Human Fly |
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.115
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.114
|
Mouse Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.113
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.113
|
Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.112
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.112
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.112
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.112
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.111
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.110
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.108
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.108
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.108
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.107
|
|
|
|
fibronectin dependent thymocyte migration
|
GO:0072681 |
1 |
0.105
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.103
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.102
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.102
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.102
|
Mouse Fly |
|
|
forebrain development
|
GO:0030900 |
302 |
0.101
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.101
|
Fly |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.098
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.098
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.098
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.096
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.096
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.095
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.095
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.094
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.094
|
Mouse |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.093
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.092
|
Worm |
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.092
|
Mouse |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
23 |
0.091
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.090
|
Human |
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.090
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.090
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.089
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.089
|
Mouse |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.088
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.087
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.087
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
20 |
0.087
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.086
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.086
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.086
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.086
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.085
|
Human |
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.085
|
Fly |
|
|
epidermis development
|
GO:0008544 |
187 |
0.084
|
Mouse |
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.084
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.084
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.084
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.084
|
Mouse |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.083
|
Mouse Fly |
|
|
extracellular matrix dependent thymocyte migration
|
GO:0072680 |
1 |
0.083
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.083
|
Mouse Fly |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.082
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
28 |
0.082
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.081
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.081
|
Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.081
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.080
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.080
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.080
|
Mouse Worm Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.080
|
Human |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.079
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.079
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.079
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
15 |
0.078
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.078
|
Human |
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.078
|
Human Fly |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.076
|
|
|
|
negative regulation of dendritic spine morphogenesis
|
GO:0061002 |
3 |
0.076
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.075
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.075
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.075
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.074
|
|
|
|
mitral valve development
|
GO:0003174 |
4 |
0.074
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.074
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.074
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.074
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.074
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.073
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.073
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.073
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.072
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.072
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.072
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.072
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.072
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.072
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.071
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.071
|
Mouse |
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.070
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.070
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.070
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.070
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.069
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.069
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.069
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.067
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.067
|
Mouse |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.067
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.067
|
Human Fly |
|
|
innate immune response
|
GO:0045087 |
157 |
0.066
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.066
|
|
|
|
bile acid and bile salt transport
|
GO:0015721 |
5 |
0.066
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.066
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.066
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.065
|
Human Mouse |
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.065
|
Mouse Worm |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.065
|
Worm |
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.065
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.063
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.063
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.063
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
39 |
0.062
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.062
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.060
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.060
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.060
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.060
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.060
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.060
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.060
|
|
|
|
substrate dependent cell migration cell extension
|
GO:0006930 |
4 |
0.059
|
|
|
|
clara cell differentiation
|
GO:0060486 |
4 |
0.059
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.059
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.059
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.059
|
Human |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.059
|
Mouse |
|
|
lung development
|
GO:0030324 |
164 |
0.059
|
Mouse |
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.059
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.059
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.059
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.058
|
Fly |
|
|
muscle system process
|
GO:0003012 |
141 |
0.058
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.058
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.057
|
|
|
|
layer formation in cerebral cortex
|
GO:0021819 |
13 |
0.057
|
Mouse |
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.056
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.056
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.056
|
Human |
|
|
heart process
|
GO:0003015 |
94 |
0.056
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.055
|
Human |
|
|
intermediate filament cytoskeleton organization
|
GO:0045104 |
26 |
0.055
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.054
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.054
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.054
|
Human |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.054
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.054
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.054
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
3 |
0.054
|
Fly |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.054
|
Human |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.053
|
Mouse |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.053
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
4 |
0.053
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.053
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.053
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.052
|
Mouse |
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.052
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.052
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.052
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.051
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.051
|
|
|
|
tripeptide transport
|
GO:0042939 |
1 |
0.051
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.051
|
Human |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.051
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.051
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.051
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
53 |
0.050
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.050
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.050
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.050
|
Mouse |
|
|
appendage development
|
GO:0048736 |
166 |
0.050
|
Mouse Fly |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.050
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.050
|
Mouse |
|
|
mesoderm development
|
GO:0007498 |
100 |
0.049
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.049
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.049
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.049
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.049
|
Mouse |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.049
|
Mouse Fly |
|
|
cell recognition
|
GO:0008037 |
83 |
0.049
|
|
|
|
neurotrophin trk receptor signaling pathway
|
GO:0048011 |
8 |
0.049
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.049
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.049
|
Zebrafish |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.049
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.048
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.048
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
27 |
0.048
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.048
|
Mouse |
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.048
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.047
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.047
|
Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.047
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.047
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.047
|
|
|
|
positive regulation of bone remodeling
|
GO:0046852 |
13 |
0.047
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.047
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.046
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.046
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.046
|
Mouse |
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.046
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.046
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.045
|
Mouse |
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
11 |
0.045
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.045
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.045
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.045
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.045
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.044
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.044
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.044
|
Mouse |
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.044
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.044
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.044
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.044
|
Mouse |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.044
|
|
|
|
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis
|
GO:2000166 |
1 |
0.044
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.044
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.044
|
Worm |
|
|
negative regulation of wnt signaling pathway involved in heart development
|
GO:0003308 |
4 |
0.043
|
Zebrafish |
|
|
skin development
|
GO:0043588 |
220 |
0.043
|
|
|
|
positive regulation of bone resorption
|
GO:0045780 |
13 |
0.043
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.042
|
Mouse |
|
|
bile acid secretion
|
GO:0032782 |
2 |
0.042
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.042
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.042
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.042
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.042
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.041
|
Mouse |
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.041
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.041
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.041
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.041
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.041
|
Human |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.041
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.041
|
|
|
|
glomerulus development
|
GO:0032835 |
40 |
0.040
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.040
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.040
|
|
|
|
prevention of polyspermy
|
GO:0060468 |
4 |
0.040
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.040
|
|
|
|
regulation of tumor necrosis factor ligand superfamily member 11 production
|
GO:2000307 |
1 |
0.040
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.040
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.040
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.040
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.040
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.039
|
|
|
|
cardiac myofibril assembly
|
GO:0055003 |
12 |
0.039
|
|
|
|
microtubule based transport
|
GO:0010970 |
50 |
0.039
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.039
|
Mouse |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.039
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.039
|
|
|
|
cerebellar granule cell precursor tangential migration
|
GO:0021935 |
1 |
0.039
|
|
|
|
positive regulation of stress fiber assembly
|
GO:0051496 |
9 |
0.038
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.038
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.038
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.038
|
Human |
|
|
regulation of ovulation
|
GO:0060278 |
3 |
0.038
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.038
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.038
|
|
|
|
trunk neural crest cell migration
|
GO:0036484 |
4 |
0.037
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.037
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.037
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.037
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.037
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.037
|
Human Fly |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.037
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.037
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.037
|
Mouse |
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
3 |
0.037
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.037
|
Human |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.036
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
20 |
0.036
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.036
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.036
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.036
|
Fly |
|
|
endocytosis
|
GO:0006897 |
168 |
0.036
|
Worm |
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
4 |
0.036
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.035
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.035
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.035
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.035
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.035
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.035
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.035
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.035
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.035
|
|
|
|
cellular phosphate ion homeostasis
|
GO:0030643 |
2 |
0.035
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.035
|
|
|
|
parathyroid hormone secretion
|
GO:0035898 |
2 |
0.035
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.035
|
Mouse |
|
|
neural tube closure
|
GO:0001843 |
90 |
0.034
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.034
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.034
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.034
|
|
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.034
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.034
|
|
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
19 |
0.034
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.034
|
Mouse |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.033
|
|
|
|
epithelial cell differentiation involved in kidney development
|
GO:0035850 |
23 |
0.033
|
Mouse |
|
|
cardiac conduction
|
GO:0061337 |
17 |
0.033
|
Human |
|
|
translation
|
GO:0006412 |
93 |
0.033
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.033
|
Mouse |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.033
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.033
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.033
|
Mouse Fly |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.033
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.032
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
24 |
0.032
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.032
|
|
|
|
av node cell to bundle of his cell communication
|
GO:0086067 |
2 |
0.032
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.032
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.032
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.032
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.032
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.032
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.032
|
|
|
|
binding of sperm to zona pellucida
|
GO:0007339 |
34 |
0.032
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.031
|
|
