Mus musculus

24 known processes

Lin7c

lin-7 homolog C (C. elegans)

(Aliases: AW125731,MGC54626,Veli3,LIN-7-C,9130007B12Rik,D2Ertd520e,MALS-3,LIN-7C,AU019331,AI303698)

Lin7c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ensheathment of neurons GO:0007272 76 0.699
neuronal action potential GO:0019228 54 0.585
protein localization to synapse GO:0035418 11 0.477
cation transport GO:0006812 399 0.450
positive regulation of ion transmembrane transport GO:0034767 24 0.450
ion transmembrane transport GO:0034220 361 0.438
protein localization to myelin sheath abaxonal region GO:0035750 1 0.419
action potential GO:0001508 78 0.416
transmission of nerve impulse GO:0019226 76 0.414
regulation of ion transport GO:0043269 215 0.401
axon ensheathment GO:0008366 76 0.388
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.379
Fly
multicellular organismal signaling GO:0035637 91 0.338
regulation of cellular component biogenesis GO:0044087 181 0.284
Fly
positive regulation of transmembrane transport GO:0034764 29 0.280
regulation of transmembrane transport GO:0034762 128 0.277
transmembrane transport GO:0055085 412 0.260
regulation of membrane potential GO:0042391 192 0.248
divalent inorganic cation transport GO:0072511 178 0.242
myelination GO:0042552 74 0.232
lateral inhibition GO:0046331 1 0.225
calcium ion transport GO:0006816 159 0.201
membrane organization GO:0061024 245 0.194
Worm
regulation of cell migration GO:0030334 219 0.172
cell adhesion GO:0007155 329 0.169
myelination in peripheral nervous system GO:0022011 19 0.159
cell chemotaxis GO:0060326 81 0.159
regulation of neutrophil chemotaxis GO:0090022 14 0.157
regulation of ion transmembrane transport GO:0034765 119 0.155
regulation of metal ion transport GO:0010959 106 0.143
gliogenesis GO:0042063 141 0.129
establishment of synaptic vesicle localization GO:0097480 57 0.128
Mouse
schwann cell development GO:0014044 22 0.126
proteasomal protein catabolic process GO:0010498 98 0.125
positive regulation of ion transport GO:0043270 65 0.123
neutrophil chemotaxis GO:0030593 36 0.120
synaptic transmission GO:0007268 329 0.119
protein localization to membrane GO:0072657 108 0.118
Worm
negative regulation of epithelial cell proliferation GO:0050680 64 0.117
regulation of calcium ion transport GO:0051924 69 0.116
neutrophil migration GO:1990266 37 0.115
myeloid leukocyte migration GO:0097529 57 0.110
regulation of system process GO:0044057 200 0.110
leukocyte chemotaxis GO:0030595 69 0.108
mrna processing GO:0006397 63 0.108
divalent metal ion transport GO:0070838 172 0.105
regulation of chemotaxis GO:0050920 53 0.105
leukocyte migration GO:0050900 124 0.103
granulocyte migration GO:0097530 43 0.101
cellular macromolecule catabolic process GO:0044265 206 0.101
multicellular organismal reproductive behavior GO:0033057 23 0.097
Worm
endoplasmic reticulum tubular network organization GO:0071786 1 0.095
synapse organization GO:0050808 125 0.095
Fly
wound healing GO:0042060 157 0.090
establishment of vesicle localization GO:0051650 81 0.089
Mouse
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.089
Zebrafish
cellular response to arsenic containing substance GO:0071243 4 0.087
purine containing compound metabolic process GO:0072521 311 0.086
mating behavior GO:0007617 20 0.085
regulation of neutrophil migration GO:1902622 14 0.083
regulation of secretion GO:0051046 274 0.083
multi multicellular organism process GO:0044706 109 0.077
Worm
granulocyte chemotaxis GO:0071621 39 0.075
mitotic cell cycle GO:0000278 195 0.074
neuron projection extension GO:1990138 64 0.072
purine ribonucleotide metabolic process GO:0009150 290 0.072
adult locomotory behavior GO:0008344 91 0.072
regulation of transforming growth factor beta2 production GO:0032909 2 0.071
mrna metabolic process GO:0016071 84 0.071
regulation of blood circulation GO:1903522 93 0.071
reproductive behavior GO:0019098 32 0.071
Worm
regulation of protein transport GO:0051223 163 0.070
neuromuscular synaptic transmission GO:0007274 16 0.069
regulation of cell substrate adhesion GO:0010810 73 0.068
protein modification by small protein conjugation or removal GO:0070647 207 0.068
homeostasis of number of cells GO:0048872 210 0.066
regulation of establishment of protein localization GO:0070201 181 0.065
protein localization to plasma membrane GO:0072659 57 0.065
Worm
rna 3 end processing GO:0031123 20 0.063
glial cell development GO:0021782 54 0.063
regulation of calcium ion import GO:0090279 10 0.061
cell matrix adhesion GO:0007160 68 0.061
rna processing GO:0006396 105 0.060
amp metabolic process GO:0046033 4 0.059
chemotaxis GO:0006935 247 0.058
regulation of actin cytoskeleton organization GO:0032956 84 0.058
actin cytoskeleton organization GO:0030036 220 0.058
regulation of epithelial cell proliferation GO:0050678 141 0.056
epithelial cell proliferation GO:0050673 174 0.055
endomembrane system organization GO:0010256 147 0.055
Worm
oocyte anterior posterior axis specification GO:0007314 2 0.055
cell cell junction organization GO:0045216 72 0.054
regulation of organelle organization GO:0033043 289 0.054
regulation of granulocyte chemotaxis GO:0071622 17 0.053
regionalization GO:0003002 337 0.053
regulation of terminal button organization GO:2000331 1 0.052
axon target recognition GO:0007412 4 0.052
memory GO:0007613 58 0.052
asymmetric neuroblast division GO:0055059 1 0.051
hindbrain development GO:0030902 128 0.051
regulation of protein localization GO:0032880 231 0.051
circulatory system process GO:0003013 197 0.051
male mating behavior GO:0060179 6 0.051
inorganic ion transmembrane transport GO:0098660 234 0.051
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.049
skeletal system morphogenesis GO:0048705 203 0.049
modification dependent protein catabolic process GO:0019941 133 0.047
macromolecule catabolic process GO:0009057 281 0.046
regulation of synaptic vesicle recycling GO:1903421 2 0.046
neural tube development GO:0021915 160 0.045
cellular amino acid metabolic process GO:0006520 103 0.045
limb morphogenesis GO:0035108 149 0.045
nucleoside triphosphate metabolic process GO:0009141 230 0.045
cellularization GO:0007349 1 0.044
multicellular organismal macromolecule catabolic process GO:0044266 1 0.044
calcium ion import GO:0070509 14 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.043
regulation of anatomical structure size GO:0090066 178 0.042
pole plasm assembly GO:0007315 2 0.041
multi organism reproductive behavior GO:0044705 29 0.041
Worm
inorganic cation transmembrane transport GO:0098662 207 0.041
courtship behavior GO:0007619 5 0.041
negative regulation of protein metabolic process GO:0051248 282 0.040
protein ubiquitination GO:0016567 171 0.040
regulation of synaptic vesicle transport GO:1902803 13 0.040
regulation of cellular component size GO:0032535 121 0.039
developmental growth involved in morphogenesis GO:0060560 138 0.039
regulation of engulfment of apoptotic cell GO:1901074 2 0.039
cellular amine metabolic process GO:0044106 44 0.039
learning or memory GO:0007611 148 0.038
positive regulation of synaptic vesicle transport GO:1902805 1 0.037
regulation of cell motility GO:2000145 236 0.037
regulation of mrna splicing via spliceosome GO:0048024 32 0.037
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.036
trophectodermal cellular morphogenesis GO:0001831 3 0.036
regulation of mitotic cell cycle GO:0007346 126 0.036
germ cell development GO:0007281 185 0.036
Fly
membrane fusion GO:0061025 38 0.035
terminal button organization GO:0072553 3 0.035
adult walking behavior GO:0007628 41 0.035
regulation of mrna processing GO:0050684 41 0.035
morphogenesis of embryonic epithelium GO:0016331 159 0.035
cellular protein catabolic process GO:0044257 155 0.035
protein catabolic process GO:0030163 221 0.034
mitochondrion distribution GO:0048311 4 0.034
intracellular protein transport GO:0006886 204 0.033
synaptic vesicle transport GO:0048489 57 0.033
Mouse
maintenance of apical basal cell polarity GO:0035090 3 0.033
Zebrafish
locomotory behavior GO:0007626 195 0.033
cell substrate adhesion GO:0031589 130 0.033
protein polyubiquitination GO:0000209 33 0.032
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.032
positive regulation of potassium ion transport GO:0043268 3 0.032
vesicle localization GO:0051648 86 0.032
Mouse
negative regulation of cell substrate adhesion GO:0010812 16 0.032
morphogenesis of a branching structure GO:0001763 203 0.031
cation transmembrane transport GO:0098655 266 0.031
myeloid cell differentiation GO:0030099 233 0.031
regulation of secretion by cell GO:1903530 249 0.031
bmp signaling pathway GO:0030509 93 0.030
positive regulation of synaptic vesicle recycling GO:1903423 1 0.030
negative regulation of response to wounding GO:1903035 77 0.030
regulation of neuron differentiation GO:0045664 281 0.030
oocyte construction GO:0007308 2 0.030
nucleotide transmembrane transport GO:1901679 2 0.030
positive regulation of calcium ion import GO:0090280 6 0.030
embryonic placenta development GO:0001892 98 0.029
cellular homeostasis GO:0019725 240 0.028
negative regulation of immune system process GO:0002683 209 0.028
regulation of actin filament based process GO:0032970 99 0.028
maternal determination of anterior posterior axis embryo GO:0008358 2 0.028
neurotransmitter secretion GO:0007269 62 0.028
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.028
regulation of cell growth GO:0001558 91 0.028
erythrocyte differentiation GO:0030218 88 0.027
positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902237 3 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
protein modification by small protein conjugation GO:0032446 187 0.027
regulation of cell shape GO:0008360 39 0.026
regulation of response to wounding GO:1903034 189 0.026
positive regulation of protein kinase activity GO:0045860 144 0.026
myeloid cell homeostasis GO:0002262 114 0.026
neural tube formation GO:0001841 108 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.026
spermatogenesis GO:0007283 284 0.025
body morphogenesis GO:0010171 45 0.025
positive regulation of calcium ion transport GO:0051928 27 0.025
positive regulation of cell development GO:0010720 237 0.025
multicellular organism growth GO:0035264 161 0.025
cellular ketone metabolic process GO:0042180 84 0.025
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.025
establishment of organelle localization GO:0051656 122 0.024
Mouse
single organism cell adhesion GO:0098602 156 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.024
cellular chemical homeostasis GO:0055082 215 0.024
regulation of synaptic vesicle endocytosis GO:1900242 2 0.024
medulla oblongata development GO:0021550 3 0.024
negative regulation of cell adhesion GO:0007162 45 0.024
regulation of synapse assembly GO:0051963 29 0.024
Fly
positive regulation of cell growth GO:0030307 33 0.024
adult behavior GO:0030534 135 0.024
positive regulation of protein modification process GO:0031401 299 0.023
establishment or maintenance of cell polarity GO:0007163 86 0.023
Zebrafish
purine containing compound catabolic process GO:0072523 213 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
male gamete generation GO:0048232 285 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
regulation of neurotransmitter levels GO:0001505 87 0.023
compound eye development GO:0048749 1 0.023
cell growth GO:0016049 130 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.022
retina morphogenesis in camera type eye GO:0060042 45 0.022
multicellular organismal protein metabolic process GO:0044268 2 0.022
calcium ion homeostasis GO:0055074 127 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
mesodermal cell migration GO:0008078 4 0.022
cell fate commitment GO:0045165 210 0.022
regulation of cell cycle GO:0051726 281 0.022
cognition GO:0050890 149 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
macromolecular complex disassembly GO:0032984 43 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
connective tissue development GO:0061448 179 0.021
keratinocyte proliferation GO:0043616 21 0.021
cytoplasmic transport GO:0016482 234 0.021
polyamine biosynthetic process GO:0006596 2 0.020
protein palmitoylation GO:0018345 14 0.020
morphogenesis of a branching epithelium GO:0061138 193 0.020
cell cell signaling involved in cell fate commitment GO:0045168 35 0.020
regulation of neuron projection development GO:0010975 169 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.020
Zebrafish
nucleotide biosynthetic process GO:0009165 78 0.020
organic anion transport GO:0015711 137 0.020
regulation of protein complex assembly GO:0043254 83 0.020
negative regulation of growth GO:0045926 99 0.020
male meiosis GO:0007140 37 0.019
negative regulation of cytoskeleton organization GO:0051494 36 0.019
regulation of neurotransmitter transport GO:0051588 35 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
leukocyte aggregation GO:0070486 1 0.019
bone morphogenesis GO:0060349 78 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.019
nucleoside monophosphate metabolic process GO:0009123 85 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
plasma membrane organization GO:0007009 90 0.019
Worm
neural nucleus development GO:0048857 22 0.019
synaptic vesicle recycling GO:0036465 19 0.018
regulation of cell adhesion GO:0030155 154 0.018
regulation of gtp catabolic process GO:0033124 113 0.018
multi organism behavior GO:0051705 62 0.018
Worm
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
sensory organ morphogenesis GO:0090596 242 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
negative regulation of wound healing GO:0061045 14 0.018
ras protein signal transduction GO:0007265 77 0.018
response to radiation GO:0009314 165 0.018
asymmetric protein localization GO:0008105 11 0.018
Worm
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.018
Zebrafish
male meiosis i GO:0007141 16 0.018
spermatid development GO:0007286 108 0.018
cellular lipid metabolic process GO:0044255 323 0.018
regulation of cell cycle process GO:0010564 160 0.018
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.018
peripheral nervous system development GO:0007422 53 0.017
metencephalon development GO:0022037 89 0.017
regulation of mrna metabolic process GO:1903311 43 0.017
sensory perception of light stimulus GO:0050953 54 0.017
establishment of protein localization to plasma membrane GO:0090002 34 0.017
anion transport GO:0006820 177 0.017
nucleotide metabolic process GO:0009117 332 0.017
limb development GO:0060173 166 0.017
amine metabolic process GO:0009308 45 0.017
cellular response to acid chemical GO:0071229 68 0.017
cation homeostasis GO:0055080 212 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
neuron projection guidance GO:0097485 141 0.017
developmental cell growth GO:0048588 84 0.017
bone development GO:0060348 120 0.017
multicellular organismal protein catabolic process GO:0044254 1 0.017
regulation of polyamine transmembrane transport GO:1902267 5 0.016
tube formation GO:0035148 140 0.016
regulation of defense response GO:0031347 233 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
response to acid chemical GO:0001101 111 0.016
skeletal system development GO:0001501 356 0.016
asymmetric stem cell division GO:0098722 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
retina development in camera type eye GO:0060041 119 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
localization within membrane GO:0051668 4 0.015
epithelial tube formation GO:0072175 130 0.015
rho protein signal transduction GO:0007266 32 0.015
regulation of cell projection organization GO:0031344 206 0.015
vacuole organization GO:0007033 38 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
regulation of endocytosis GO:0030100 69 0.015
mrna splicing via spliceosome GO:0000398 43 0.015
organelle localization GO:0051640 179 0.015
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.015
positive regulation of nervous system development GO:0051962 221 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
epithelial cell development GO:0002064 159 0.015
Fly
establishment of protein localization to membrane GO:0090150 54 0.015
regulation of actin filament length GO:0030832 45 0.014
muscle cell differentiation GO:0042692 261 0.014
blood circulation GO:0008015 195 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
oxidation reduction process GO:0055114 342 0.014
lung morphogenesis GO:0060425 50 0.014
morphogenesis of an epithelial sheet GO:0002011 27 0.014
Human
gonad development GO:0008406 141 0.014
dna endoreduplication GO:0042023 4 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
regulation of intracellular protein transport GO:0033157 82 0.014
potassium ion transport GO:0006813 52 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
heart process GO:0003015 94 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
synaptic vesicle localization GO:0097479 59 0.014
Mouse
positive regulation of organelle organization GO:0010638 128 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
negative regulation of synapse assembly GO:0051964 3 0.013
regulation of tube size GO:0035150 57 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
renal system development GO:0072001 225 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
lung development GO:0030324 164 0.013
long term memory GO:0007616 15 0.013
intracellular distribution of mitochondria GO:0048312 1 0.013
cerebellar cortex development GO:0021695 48 0.013
dna dependent dna replication GO:0006261 24 0.013
positive regulation of mrna metabolic process GO:1903313 17 0.013
regulation of mrna 3 end processing GO:0031440 6 0.013
regulation of actin filament polymerization GO:0030833 38 0.013
negative regulation of mitotic cell cycle GO:0045930 58 0.013
oogenesis GO:0048477 56 0.013
Fly
meiosis i GO:0007127 60 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
protein digestion GO:0044256 1 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.012
oocyte axis specification GO:0007309 2 0.012
ribonucleoprotein complex disassembly GO:0032988 3 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
muscle tissue development GO:0060537 308 0.012
regulation of bmp signaling pathway GO:0030510 60 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
organophosphate catabolic process GO:0046434 232 0.012
camera type eye development GO:0043010 266 0.012
synaptic vesicle endocytosis GO:0048488 19 0.012
negative regulation of keratinocyte proliferation GO:0010839 7 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
positive regulation of neuron projection development GO:0010976 79 0.011
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902235 11 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
amp biosynthetic process GO:0006167 2 0.011
regulation of neurotransmitter secretion GO:0046928 29 0.011
positive regulation of protein transport GO:0051222 93 0.011
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.011
response to inorganic substance GO:0010035 96 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
positive regulation of synaptic vesicle endocytosis GO:1900244 1 0.011
sodium ion transport GO:0006814 73 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
organophosphate ester transport GO:0015748 28 0.011
heart contraction GO:0060047 93 0.011
negative regulation of defense response GO:0031348 77 0.011
embryonic appendage morphogenesis GO:0035113 126 0.011
protein polymerization GO:0051258 57 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
regulation of feeding behavior GO:0060259 3 0.010
response to ph GO:0009268 14 0.010
stem cell proliferation GO:0072089 117 0.010
positive regulation of cell motility GO:2000147 116 0.010
regulation of inflammatory response GO:0050727 147 0.010
mitochondrion localization GO:0051646 9 0.010
leukocyte differentiation GO:0002521 342 0.010
organic cyclic compound catabolic process GO:1901361 295 0.010
establishment of spindle orientation GO:0051294 15 0.010
positive regulation of endocytosis GO:0045807 42 0.010
ossification GO:0001503 216 0.010
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.010
mrna 3 end processing GO:0031124 16 0.010

Lin7c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.152
nervous system disease DOID:863 0 0.152
x linked disease DOID:0050735 0 0.042
central nervous system disease DOID:331 0 0.027
neurodegenerative disease DOID:1289 0 0.027
retinal disease DOID:5679 0 0.020
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
retinal degeneration DOID:8466 0 0.015