Mus musculus

69 known processes

Ttc21b

tetratricopeptide repeat domain 21B

(Aliases: aln,2410066K11Rik,mKIAA1992,Thm1)

Ttc21b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 102 0.213
cilium assembly GO:0042384 81 0.154
cellular component assembly involved in morphogenesis GO:0010927 139 0.082
organelle assembly GO:0070925 177 0.068
cellular amino acid metabolic process GO:0006520 103 0.060
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
cellular amine metabolic process GO:0044106 44 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
regulation of cellular ketone metabolic process GO:0010565 66 0.036
cellular ketone metabolic process GO:0042180 84 0.035
nucleotide metabolic process GO:0009117 332 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
microtubule based process GO:0007017 236 0.030
apoptotic signaling pathway GO:0097190 306 0.030
heterocycle catabolic process GO:0046700 280 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
small gtpase mediated signal transduction GO:0007264 97 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
amine metabolic process GO:0009308 45 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.027
membrane organization GO:0061024 245 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
regulation of organelle organization GO:0033043 289 0.026
regulation of cell activation GO:0050865 289 0.026
nucleoside catabolic process GO:0009164 206 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
nucleoside metabolic process GO:0009116 246 0.025
regulation of cell cycle GO:0051726 281 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
nucleotide catabolic process GO:0009166 217 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
male gamete generation GO:0048232 285 0.023
peptidyl amino acid modification GO:0018193 336 0.023
spermatid development GO:0007286 108 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
transmembrane transport GO:0055085 412 0.023
positive regulation of protein modification process GO:0031401 299 0.023
spermatogenesis GO:0007283 284 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
cytoplasmic transport GO:0016482 234 0.022
cellular response to dna damage stimulus GO:0006974 207 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
purine containing compound catabolic process GO:0072523 213 0.021
macromolecule catabolic process GO:0009057 281 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
ras protein signal transduction GO:0007265 77 0.021
multicellular organism growth GO:0035264 161 0.021
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
protein catabolic process GO:0030163 221 0.020
organophosphate catabolic process GO:0046434 232 0.020
aromatic compound catabolic process GO:0019439 286 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
organelle fission GO:0048285 170 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
response to organonitrogen compound GO:0010243 246 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
cation transport GO:0006812 399 0.019
protein ubiquitination GO:0016567 171 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
meiotic nuclear division GO:0007126 115 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
dna metabolic process GO:0006259 303 0.019
glycosyl compound catabolic process GO:1901658 206 0.018
intracellular protein transport GO:0006886 204 0.018
nuclear division GO:0000280 158 0.018
immune effector process GO:0002252 321 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
camera type eye development GO:0043010 266 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
regulation of protein localization GO:0032880 231 0.018
negative regulation of molecular function GO:0044092 258 0.017
cell adhesion GO:0007155 329 0.017
mitotic cell cycle process GO:1903047 159 0.017
sensory perception GO:0007600 245 0.017
protein maturation GO:0051604 176 0.017
germ cell development GO:0007281 185 0.017
chromatin organization GO:0006325 206 0.017
cation transmembrane transport GO:0098655 266 0.017
methylation GO:0032259 134 0.017
endomembrane system organization GO:0010256 147 0.017
regulation of cell projection organization GO:0031344 206 0.017
muscle tissue development GO:0060537 308 0.016
regulation of membrane potential GO:0042391 192 0.016
striated muscle tissue development GO:0014706 293 0.016
ion transmembrane transport GO:0034220 361 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
negative regulation of cell development GO:0010721 169 0.016
response to radiation GO:0009314 165 0.016
mrna metabolic process GO:0016071 84 0.016
leukocyte differentiation GO:0002521 342 0.016
regulation of transferase activity GO:0051338 263 0.016
regulation of ion transport GO:0043269 215 0.016
protein localization to organelle GO:0033365 185 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
nitrogen compound transport GO:0071705 271 0.015
adult behavior GO:0030534 135 0.015
regulation of neuron differentiation GO:0045664 281 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
skeletal system development GO:0001501 356 0.015
smoothened signaling pathway GO:0007224 105 0.015
organelle localization GO:0051640 179 0.015
cytokine production GO:0001816 319 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
mapk cascade GO:0000165 281 0.015
fat cell differentiation GO:0045444 160 0.015
spermatid differentiation GO:0048515 115 0.015
gland development GO:0048732 330 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of hydrolase activity GO:0051336 246 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
cell type specific apoptotic process GO:0097285 268 0.014
anatomical structure homeostasis GO:0060249 145 0.014
locomotory behavior GO:0007626 195 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
nuclear transport GO:0051169 139 0.014
regulation of secretion by cell GO:1903530 249 0.014
negative regulation of nervous system development GO:0051961 156 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
regulation of protein maturation GO:1903317 96 0.014
lymphocyte differentiation GO:0030098 242 0.014
multicellular organismal signaling GO:0035637 91 0.014
intracellular mrna localization GO:0008298 4 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
neuron death GO:0070997 154 0.014
cellular homeostasis GO:0019725 240 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
chemotaxis GO:0006935 247 0.013
t cell activation GO:0042110 289 0.013
cellular protein catabolic process GO:0044257 155 0.013
cognition GO:0050890 149 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
positive regulation of cell activation GO:0050867 158 0.013
axonogenesis GO:0007409 274 0.013
oxidation reduction process GO:0055114 342 0.013
oocyte axis specification GO:0007309 2 0.013
action potential GO:0001508 78 0.013
skin development GO:0043588 220 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
regulation of proteolysis GO:0030162 164 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.013
rna processing GO:0006396 105 0.013
regulation of defense response GO:0031347 233 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of cell cycle process GO:0010564 160 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
lipid biosynthetic process GO:0008610 179 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
cellular lipid metabolic process GO:0044255 323 0.013
protein targeting GO:0006605 143 0.013
covalent chromatin modification GO:0016569 163 0.013
regulation of cell adhesion GO:0030155 154 0.013
stem cell differentiation GO:0048863 268 0.013
innate immune response GO:0045087 157 0.013
rho protein signal transduction GO:0007266 32 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
renal system development GO:0072001 225 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
urogenital system development GO:0001655 261 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
neural tube development GO:0021915 160 0.012
regulation of anatomical structure size GO:0090066 178 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
glucose homeostasis GO:0042593 128 0.012
circadian rhythm GO:0007623 114 0.012
oocyte construction GO:0007308 2 0.012
regulation of hormone levels GO:0010817 211 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
regionalization GO:0003002 337 0.012
protein processing GO:0016485 163 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
translation GO:0006412 93 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
synaptic transmission GO:0007268 329 0.012
protein localization to membrane GO:0072657 108 0.012
protein polymerization GO:0051258 57 0.012
response to organic cyclic compound GO:0014070 198 0.012
regulation of t cell activation GO:0050863 170 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
transmission of nerve impulse GO:0019226 76 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
heart morphogenesis GO:0003007 178 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
homeostasis of number of cells GO:0048872 210 0.012
ear development GO:0043583 200 0.012
muscle cell differentiation GO:0042692 261 0.012
macromolecule methylation GO:0043414 120 0.012
respiratory system development GO:0060541 190 0.012
regulation of kinase activity GO:0043549 249 0.011
endocytosis GO:0006897 168 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
regulation of neuron death GO:1901214 134 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
lateral inhibition GO:0046331 1 0.011
regulation of mapk cascade GO:0043408 248 0.011
stem cell maintenance GO:0019827 130 0.011
negative regulation of immune system process GO:0002683 209 0.011
actin cytoskeleton organization GO:0030036 220 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
mitotic cell cycle GO:0000278 195 0.011
b cell activation GO:0042113 161 0.011
response to peptide hormone GO:0043434 127 0.011
regulation of intracellular transport GO:0032386 159 0.011
atp catabolic process GO:0006200 55 0.011
neuron apoptotic process GO:0051402 142 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
response to insulin GO:0032868 100 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
male anatomical structure morphogenesis GO:0090598 4 0.011
rhythmic process GO:0048511 174 0.011
response to growth factor GO:0070848 198 0.011
dna repair GO:0006281 107 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
positive regulation of cell development GO:0010720 237 0.011
regulation of protein processing GO:0070613 96 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
positive regulation of transferase activity GO:0051347 167 0.011
male genitalia morphogenesis GO:0048808 4 0.011
ossification GO:0001503 216 0.011
tube formation GO:0035148 140 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
chromatin modification GO:0016568 187 0.011
telencephalon development GO:0021537 186 0.011
cytokinetic process GO:0032506 2 0.011
negative regulation of cell cycle GO:0045786 123 0.011
carbohydrate homeostasis GO:0033500 128 0.011
inflammatory response GO:0006954 244 0.011
regulation of protein kinase activity GO:0045859 232 0.011
cell growth GO:0016049 130 0.011
response to light stimulus GO:0009416 135 0.011
forebrain development GO:0030900 302 0.011
negative regulation of organelle organization GO:0010639 90 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.011
placenta development GO:0001890 140 0.011
dna recombination GO:0006310 92 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
compound eye development GO:0048749 1 0.011
developmental maturation GO:0021700 193 0.011
positive regulation of nervous system development GO:0051962 221 0.011
dephosphorylation GO:0016311 129 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
mrna processing GO:0006397 63 0.011
circulatory system process GO:0003013 197 0.011
regulation of cellular component size GO:0032535 121 0.011
atp metabolic process GO:0046034 75 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
positive regulation of cell death GO:0010942 224 0.010
meiotic cell cycle GO:0051321 122 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
myeloid cell differentiation GO:0030099 233 0.010
epithelial tube formation GO:0072175 130 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
cellular chemical homeostasis GO:0055082 215 0.010
positive regulation of organelle organization GO:0010638 128 0.010
response to inorganic substance GO:0010035 96 0.010
negative regulation of protein modification process GO:0031400 163 0.010
regulation of secretion GO:0051046 274 0.010
regulation of homeostatic process GO:0032844 182 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
rna splicing GO:0008380 54 0.010
regulation of nucleotide metabolic process GO:0006140 169 0.010
sensory perception of sound GO:0007605 97 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
maintenance of location GO:0051235 89 0.010
carbohydrate metabolic process GO:0005975 230 0.010
positive regulation of growth GO:0045927 104 0.010
microtubule based transport GO:0010970 50 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010

Ttc21b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
central nervous system disease DOID:331 0 0.018
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.011
musculoskeletal system disease DOID:17 0 0.011
neurodegenerative disease DOID:1289 0 0.010