Mus musculus

199 known processes

T

brachyury

(Aliases: Tl3,Tl2,me75,cou,T1,Lr,Low,D17Mit170,Bra)

T biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axis elongation involved in somitogenesis GO:0090245 4 0.998
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.997
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.997
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.993
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.991
paraxial mesodermal cell fate commitment GO:0048343 2 0.991
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.990
inner medullary collecting duct development GO:0072061 2 0.986
paraxial mesodermal cell differentiation GO:0048342 2 0.980
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.979
somatotropin secreting cell differentiation GO:0060126 4 0.978
hematopoietic stem cell proliferation GO:0071425 13 0.976
head morphogenesis GO:0060323 34 0.973
Mouse
cell differentiation in spinal cord GO:0021515 53 0.967
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.966
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.965
mesonephric duct formation GO:0072181 2 0.962
tongue development GO:0043586 18 0.961
Mouse
outer medullary collecting duct development GO:0072060 1 0.961
lung induction GO:0060492 3 0.960
stem cell maintenance GO:0019827 130 0.958
Mouse
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.954
establishment of organ orientation GO:0048561 1 0.950
positive regulation of interleukin 8 secretion GO:2000484 1 0.950
nephric duct formation GO:0072179 4 0.950
diencephalon development GO:0021536 63 0.949
Mouse
metanephric loop of henle development GO:0072236 4 0.948
mesonephric duct morphogenesis GO:0072180 4 0.946
regulation of testosterone biosynthetic process GO:2000224 2 0.942
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.941
regulation of cardiac muscle tissue development GO:0055024 31 0.941
Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.939
segmentation GO:0035282 93 0.934
renal vesicle induction GO:0072034 3 0.931
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.928
negative regulation of prostatic bud formation GO:0060686 4 0.927
embryonic organ morphogenesis GO:0048562 276 0.923
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.921
spinal cord development GO:0021510 81 0.920
Mouse
skeletal system morphogenesis GO:0048705 203 0.918
polarity specification of proximal distal axis GO:0010085 2 0.917
hypophysis morphogenesis GO:0048850 3 0.917
cardiac right atrium morphogenesis GO:0003213 3 0.914
forelimb morphogenesis GO:0035136 40 0.910
Mouse
midbrain hindbrain boundary maturation GO:0021732 1 0.907
embryonic skeletal system development GO:0048706 120 0.905
bmp signaling pathway GO:0030509 93 0.904
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.902
regionalization GO:0003002 337 0.900
neural tube closure GO:0001843 90 0.899
forebrain neuron differentiation GO:0021879 52 0.895
Mouse
forebrain neuron fate commitment GO:0021877 13 0.894
Mouse
renal inner medulla development GO:0072053 3 0.891
establishment of anatomical structure orientation GO:0048560 1 0.889
mesonephric tubule formation GO:0072172 11 0.884
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.883
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.883
oviduct development GO:0060066 3 0.880
skeletal system development GO:0001501 356 0.878
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.870
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.867
striated muscle tissue development GO:0014706 293 0.862
Mouse
forebrain regionalization GO:0021871 25 0.862
Mouse
cell fate determination GO:0001709 32 0.857
Mouse
somite development GO:0061053 81 0.857
midbrain hindbrain boundary development GO:0030917 9 0.857
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.856
cerebral cortex development GO:0021987 86 0.855
Mouse
spemann organizer formation GO:0060061 2 0.854
renal outer medulla development GO:0072054 2 0.854
pancreatic a cell fate commitment GO:0003326 2 0.843
forebrain development GO:0030900 302 0.839
Mouse
mesonephric tubule development GO:0072164 94 0.838
spinal cord association neuron differentiation GO:0021527 14 0.837
androgen biosynthetic process GO:0006702 4 0.834
regulation of muscle tissue development GO:1901861 97 0.833
Mouse
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.829
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.827
auditory receptor cell fate determination GO:0042668 3 0.824
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.824
inner ear morphogenesis GO:0042472 101 0.824
Mouse
appendage morphogenesis GO:0035107 149 0.819
Mouse
negative regulation of androgen biosynthetic process GO:2000180 1 0.817
kidney rudiment formation GO:0072003 3 0.815
regulation of axon diameter GO:0031133 6 0.815
ear morphogenesis GO:0042471 118 0.815
Mouse
central nervous system morphogenesis GO:0021551 2 0.814
hindbrain formation GO:0021576 1 0.813
regulation of organ growth GO:0046620 61 0.809
Mouse
regulation of anagen GO:0051884 1 0.807
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.807
paramesonephric duct development GO:0061205 3 0.807
metanephros morphogenesis GO:0003338 24 0.805
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.804
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.802
embryonic hindlimb morphogenesis GO:0035116 32 0.794
Mouse
stem cell differentiation GO:0048863 268 0.792
fibroblast growth factor production GO:0090269 4 0.789
establishment of endothelial blood brain barrier GO:0014045 3 0.782
limbic system development GO:0021761 72 0.781
Mouse
central nervous system vasculogenesis GO:0022009 3 0.774
morphogenesis of a polarized epithelium GO:0001738 37 0.773
hindlimb morphogenesis GO:0035137 42 0.772
Mouse
epithelial tube formation GO:0072175 130 0.770
specification of organ identity GO:0010092 30 0.769
Mouse
gas homeostasis GO:0033483 3 0.768
embryonic epithelial tube formation GO:0001838 130 0.767
olfactory bulb development GO:0021772 30 0.765
Mouse
central nervous system neuron differentiation GO:0021953 162 0.760
Mouse
pyramidal neuron migration GO:0021852 1 0.756
maintenance of cell number GO:0098727 3 0.753
epithelial cell morphogenesis GO:0003382 41 0.747
olfactory lobe development GO:0021988 32 0.747
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.746
Mouse
cervix development GO:0060067 2 0.746
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.739
foregut regionalization GO:0060423 3 0.738
tube formation GO:0035148 140 0.737
testosterone biosynthetic process GO:0061370 2 0.737
face morphogenesis GO:0060325 29 0.736
Mouse
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.736
bone morphogenesis GO:0060349 78 0.734
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.734
cerebellum formation GO:0021588 1 0.729
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.726
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.725
embryonic skeletal system morphogenesis GO:0048704 91 0.721
Mouse
stem cell proliferation GO:0072089 117 0.719
Mouse
negative regulation of alcohol biosynthetic process GO:1902931 4 0.719
somatic stem cell maintenance GO:0035019 47 0.715
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.694
renal vesicle development GO:0072087 17 0.694
regulation of heart growth GO:0060420 31 0.693
Mouse
negative regulation of testosterone biosynthetic process GO:2000225 1 0.692
astrocyte fate commitment GO:0060018 4 0.691
olfactory bulb interneuron development GO:0021891 7 0.686
cell proliferation in forebrain GO:0021846 30 0.685
lung field specification GO:0060424 3 0.683
endodermal cell fate specification GO:0001714 4 0.678
Mouse
neuron migration GO:0001764 122 0.676
Mouse
regulation of interleukin 8 secretion GO:2000482 2 0.674
nephric duct morphogenesis GO:0072178 7 0.672
heart morphogenesis GO:0003007 178 0.672
Zebrafish Mouse
fungiform papilla development GO:0061196 6 0.669
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.666
branching involved in ureteric bud morphogenesis GO:0001658 56 0.666
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.665
limb development GO:0060173 166 0.664
Mouse
embryonic forelimb morphogenesis GO:0035115 32 0.663
Mouse
appendage development GO:0048736 166 0.661
Mouse
neural tube development GO:0021915 160 0.657
epithelial cell proliferation GO:0050673 174 0.656
Mouse
pallium development GO:0021543 120 0.650
Mouse
embryonic heart tube development GO:0035050 65 0.649
Zebrafish Mouse
mesonephric duct development GO:0072177 5 0.643
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.642
palate development GO:0060021 76 0.641
Mouse
cardiac ventricle development GO:0003231 83 0.641
Mouse
cell fate commitment GO:0045165 210 0.641
Mouse
chondrocyte differentiation GO:0002062 72 0.641
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.631
face development GO:0060324 38 0.629
Mouse
stem cell development GO:0048864 219 0.628
Mouse
extracellular matrix organization GO:0030198 147 0.627
odontogenesis GO:0042476 78 0.618
Mouse
forebrain morphogenesis GO:0048853 17 0.616
metanephric tubule development GO:0072170 18 0.613
neural tube patterning GO:0021532 43 0.610
cardiac muscle tissue morphogenesis GO:0055008 44 0.610
Mouse
neuron fate determination GO:0048664 9 0.610
mesodermal cell differentiation GO:0048333 22 0.606
transdifferentiation GO:0060290 1 0.606
cellular response to parathyroid hormone stimulus GO:0071374 2 0.603
heart formation GO:0060914 16 0.601
Mouse
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.600
regulation of ketone biosynthetic process GO:0010566 2 0.597
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.593
mesenchyme morphogenesis GO:0072132 32 0.593
Mouse
embryonic eye morphogenesis GO:0048048 29 0.592
Mouse
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.591
cerebral cortex neuron differentiation GO:0021895 19 0.590
Mouse
cop9 signalosome assembly GO:0010387 2 0.588
limb morphogenesis GO:0035108 149 0.588
Mouse
negative regulation of nervous system development GO:0051961 156 0.585
Mouse
uterus morphogenesis GO:0061038 2 0.583
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.583
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.580
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.578
ureteric bud morphogenesis GO:0060675 62 0.578
response to parathyroid hormone GO:0071107 3 0.576
purine nucleotide catabolic process GO:0006195 211 0.574
loop of henle development GO:0072070 10 0.567
positive regulation of epithelial cell proliferation GO:0050679 68 0.565
Mouse
nephron tubule formation GO:0072079 20 0.564
regulation of fibroblast growth factor production GO:0090270 4 0.562
dorsal spinal cord development GO:0021516 20 0.555
regulation of canonical wnt signaling pathway GO:0060828 82 0.553
Mouse
urogenital system development GO:0001655 261 0.553
Mouse Fly
blastocyst formation GO:0001825 33 0.552
Mouse
nephron tubule morphogenesis GO:0072078 68 0.550
mesenchyme development GO:0060485 152 0.550
Zebrafish Mouse
embryonic limb morphogenesis GO:0030326 126 0.548
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.547
Mouse
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.547
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.545
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 5 0.545
hippocampus development GO:0021766 52 0.542
neuroblast differentiation GO:0014016 2 0.540
neural tube formation GO:0001841 108 0.537
mesenchymal cell differentiation GO:0048762 107 0.536
Mouse
metanephric nephron tubule development GO:0072234 16 0.533
regulation of wnt signaling pathway GO:0030111 123 0.530
Mouse
kidney epithelium development GO:0072073 121 0.530
auditory receptor cell fate specification GO:0042667 1 0.529
cell differentiation in hindbrain GO:0021533 24 0.525
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.524
metanephric tubule morphogenesis GO:0072173 9 0.523
cartilage development GO:0051216 140 0.523
tube closure GO:0060606 91 0.519
metanephric nephron morphogenesis GO:0072273 19 0.519
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.519
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.517
Mouse
artery development GO:0060840 53 0.514
Mouse
mesenchymal cell development GO:0014031 93 0.514
Mouse
ear development GO:0043583 200 0.511
Mouse
primitive streak formation GO:0090009 10 0.511
regulation of transforming growth factor beta2 production GO:0032909 2 0.507
regulation of stem cell proliferation GO:0072091 78 0.502
Mouse
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000058 14 0.502
regulation of cardiac chamber morphogenesis GO:1901219 2 0.499
Mouse
embryonic viscerocranium morphogenesis GO:0048703 8 0.496
negative regulation of protein modification process GO:0031400 163 0.496
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.494
hormone metabolic process GO:0042445 86 0.494
hindbrain morphogenesis GO:0021575 46 0.493
pancreatic pp cell differentiation GO:0003312 2 0.489
embryonic heart tube formation GO:0003144 1 0.487
sclerotome development GO:0061056 4 0.479
renal tubule development GO:0061326 87 0.475
Fly
positive regulation of muscle cell differentiation GO:0051149 39 0.475
Mouse
metanephric epithelium development GO:0072207 21 0.473
b cell activation GO:0042113 161 0.471
Mouse
oxidation reduction process GO:0055114 342 0.470
forebrain anterior posterior pattern specification GO:0021797 5 0.470
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.467
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.464
positive regulation of striated muscle tissue development GO:0045844 31 0.458
Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.458
cochlea morphogenesis GO:0090103 22 0.456
Mouse
formation of radial glial scaffolds GO:0021943 4 0.455
determination of heart left right asymmetry GO:0061371 48 0.455
regulation of establishment of planar polarity GO:0090175 28 0.454
primary neural tube formation GO:0014020 95 0.451
cellular ketone metabolic process GO:0042180 84 0.451
cell fate specification GO:0001708 72 0.450
Mouse
muscle tissue morphogenesis GO:0060415 53 0.450
Mouse
thalamus development GO:0021794 11 0.448
renal vesicle morphogenesis GO:0072077 15 0.447
neural crest cell differentiation GO:0014033 54 0.446
Mouse
determination of left right symmetry GO:0007368 80 0.445
modification dependent macromolecule catabolic process GO:0043632 133 0.445
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.438
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.438
Mouse
pericardium development GO:0060039 16 0.436
Mouse
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.430
interleukin 8 secretion GO:0072606 3 0.430
regulation of epithelial cell proliferation GO:0050678 141 0.430
Mouse
cell proliferation in hindbrain GO:0021534 10 0.429
pancreatic pp cell fate commitment GO:0003329 2 0.425
mesonephric tubule morphogenesis GO:0072171 63 0.424
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.421
rostrocaudal neural tube patterning GO:0021903 12 0.417
digestive tract development GO:0048565 190 0.416
positive regulation of anagen GO:0051885 1 0.413
myotube differentiation GO:0014902 105 0.410
Mouse
kidney morphogenesis GO:0060993 83 0.410
oxygen homeostasis GO:0032364 2 0.409
positive regulation of heart growth GO:0060421 18 0.408
Mouse
muscle cell development GO:0055001 133 0.407
Mouse
ectoderm formation GO:0001705 3 0.405
kidney development GO:0001822 213 0.400
positive regulation of smoothened signaling pathway GO:0045880 23 0.399
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.395
regulation of stem cell differentiation GO:2000736 50 0.395
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.395
regulation of cardiac muscle tissue growth GO:0055021 26 0.393
Mouse
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.393
his purkinje system development GO:0003164 4 0.392
Mouse
metanephric collecting duct development GO:0072205 7 0.392
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.390
regulation of asymmetric cell division GO:0009786 4 0.387
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.384
positive regulation of mesonephros development GO:0061213 20 0.383
regulation of homeostatic process GO:0032844 182 0.380
steroid metabolic process GO:0008202 119 0.377
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.377
cellular response to lipid GO:0071396 145 0.375
Mouse
small molecule biosynthetic process GO:0044283 132 0.375
positive regulation of transcription by glucose GO:0046016 3 0.372
negative regulation of fibroblast growth factor production GO:0090272 2 0.370
purine ribonucleoside catabolic process GO:0046130 205 0.369
visceral motor neuron differentiation GO:0021524 3 0.367
Mouse
lipid biosynthetic process GO:0008610 179 0.365
regulation of neuron projection development GO:0010975 169 0.365
Mouse
his purkinje system cell differentiation GO:0060932 2 0.365
Mouse
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.363
positive regulation of cardiac muscle tissue development GO:0055025 19 0.361
Mouse
mitral valve morphogenesis GO:0003183 4 0.360
aortic valve morphogenesis GO:0003180 4 0.358
small gtpase mediated signal transduction GO:0007264 97 0.357
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.357
metanephric capsule specification GO:0072267 1 0.356
developmental growth involved in morphogenesis GO:0060560 138 0.356
Zebrafish Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.356
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.354
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.354
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.352
nephron development GO:0072006 109 0.352
body morphogenesis GO:0010171 45 0.349
Mouse
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.348
digestive system development GO:0055123 200 0.348
trophectodermal cell differentiation GO:0001829 21 0.348
Mouse
cerebellum morphogenesis GO:0021587 42 0.347
pancreas development GO:0031016 57 0.346
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.345
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.345
Mouse
telencephalon cell migration GO:0022029 55 0.342
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.342
metanephric dct cell differentiation GO:0072240 3 0.341
paraxial mesoderm morphogenesis GO:0048340 10 0.340
regulation of metanephros development GO:0072215 15 0.337
forebrain generation of neurons GO:0021872 63 0.336
Mouse
cartilage morphogenesis GO:0060536 11 0.335
muscle tissue development GO:0060537 308 0.334
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.334
renal system development GO:0072001 225 0.333
Mouse Fly
response to fibroblast growth factor GO:0071774 47 0.331
Mouse
positive regulation of nervous system development GO:0051962 221 0.329
telencephalon development GO:0021537 186 0.326
Mouse
hindbrain development GO:0030902 128 0.323
Mouse
transforming growth factor beta2 production GO:0032906 2 0.322
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.322
hematopoietic progenitor cell differentiation GO:0002244 143 0.321
mesenchymal to epithelial transition GO:0060231 12 0.321
mesonephros development GO:0001823 97 0.319
positive regulation of cell death GO:0010942 224 0.318
regulation of kidney development GO:0090183 40 0.313
protein modification by small protein conjugation GO:0032446 187 0.310
mammary placode formation GO:0060596 4 0.310
Mouse
positive regulation of dna templated transcription initiation GO:2000144 5 0.309
somitogenesis GO:0001756 69 0.308
neural precursor cell proliferation GO:0061351 121 0.308
regulation of nucleoside metabolic process GO:0009118 130 0.307
cardiac muscle tissue development GO:0048738 130 0.307
Mouse
regulation of cell division GO:0051302 76 0.305
cell division GO:0051301 120 0.304
mesoderm development GO:0007498 100 0.304
olfactory bulb interneuron differentiation GO:0021889 12 0.304
mesoderm formation GO:0001707 62 0.303
negative regulation of hormone metabolic process GO:0032351 4 0.303
pituitary gland development GO:0021983 38 0.303
Mouse
skin development GO:0043588 220 0.302
cardiac muscle cell fate commitment GO:0060923 6 0.302
Mouse
gastrulation GO:0007369 116 0.302
nephron morphogenesis GO:0072028 69 0.301
cochlea development GO:0090102 35 0.300
Mouse
nucleoside catabolic process GO:0009164 206 0.300
digestive tract morphogenesis GO:0048546 147 0.299
androgen metabolic process GO:0008209 11 0.298
development of primary male sexual characteristics GO:0046546 88 0.298
metanephric nephron epithelium development GO:0072243 19 0.297
metanephric renal vesicle morphogenesis GO:0072283 12 0.296
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.296
tendon formation GO:0035992 4 0.295
adenohypophysis development GO:0021984 14 0.293
positive regulation of kidney development GO:0090184 28 0.292
metanephric capsule morphogenesis GO:0072265 1 0.292
endodermal cell fate commitment GO:0001711 12 0.291
Mouse
brain morphogenesis GO:0048854 32 0.289
glucose metabolic process GO:0006006 92 0.287
negative regulation of lipid metabolic process GO:0045833 30 0.286
epithelial tube morphogenesis GO:0060562 303 0.285
regulation of jnk cascade GO:0046328 62 0.284
amine metabolic process GO:0009308 45 0.284
negative regulation of cellular protein metabolic process GO:0032269 247 0.283
lung development GO:0030324 164 0.280
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.279
negative regulation of cell proliferation GO:0008285 296 0.278
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.278
Mouse
regulation of cellular protein catabolic process GO:1903362 61 0.277
respiratory tube development GO:0030323 167 0.276
Mouse
regulation of auditory receptor cell differentiation GO:0045607 4 0.275
cell migration involved in gastrulation GO:0042074 13 0.273
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.272
sensory organ morphogenesis GO:0090596 242 0.271
Mouse
telencephalon regionalization GO:0021978 14 0.270
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.270
Mouse
notochord development GO:0030903 20 0.269
endocrine system development GO:0035270 98 0.269
Mouse
morphogenesis of a branching structure GO:0001763 203 0.268
Mouse
endoderm development GO:0007492 45 0.265
Mouse
dentate gyrus development GO:0021542 14 0.264
regulation of stem cell maintenance GO:2000036 17 0.264
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.263
Mouse
enteroendocrine cell differentiation GO:0035883 16 0.262
forebrain neuroblast division GO:0021873 9 0.261
regulation of bmp signaling pathway GO:0030510 60 0.259
Zebrafish
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 0.258
jnk cascade GO:0007254 72 0.257
branching morphogenesis of an epithelial tube GO:0048754 159 0.256
Mouse
cardiac muscle tissue growth GO:0055017 37 0.256
Mouse
muscle cell fate commitment GO:0042693 11 0.256
Mouse
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.255
paraxial mesoderm formation GO:0048341 6 0.253
regulation of vascular wound healing GO:0061043 2 0.253
positive regulation of keratinocyte proliferation GO:0010838 4 0.251
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.251
respiratory system development GO:0060541 190 0.250
Mouse
non canonical wnt signaling pathway GO:0035567 33 0.250
organic hydroxy compound metabolic process GO:1901615 203 0.250
post anal tail morphogenesis GO:0036342 23 0.249
positive regulation of protein phosphorylation GO:0001934 242 0.249
Mouse
clara cell differentiation GO:0060486 4 0.248
regulation of cell projection size GO:0032536 6 0.248
nephron tubule development GO:0072080 84 0.248
renal capsule morphogenesis GO:0072128 1 0.247
mesoderm morphogenesis GO:0048332 64 0.247
embryonic digit morphogenesis GO:0042733 56 0.247
Mouse
male gonad development GO:0008584 88 0.246
neuron projection guidance GO:0097485 141 0.245
Mouse
negative regulation of synapse maturation GO:2000297 2 0.243
regulation of b cell activation GO:0050864 81 0.242
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.241
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.241
protein catabolic process GO:0030163 221 0.240
metanephros development GO:0001656 79 0.240
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.239
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.238
purine nucleoside metabolic process GO:0042278 241 0.237
metanephric tubule formation GO:0072174 6 0.236
negative regulation of protein metabolic process GO:0051248 282 0.235
negative regulation of fat cell differentiation GO:0045599 36 0.235
negative regulation of steroid biosynthetic process GO:0010894 8 0.234
metanephric capsule formation GO:0072266 1 0.232
rhythmic process GO:0048511 174 0.231
cellular chemical homeostasis GO:0055082 215 0.229
central nervous system neuron development GO:0021954 67 0.229
regulation of binding GO:0051098 111 0.229
apoptotic process involved in development GO:1902742 28 0.229
chromatin modification GO:0016568 187 0.228
regulation of neural retina development GO:0061074 3 0.228
dopaminergic neuron differentiation GO:0071542 14 0.227
ventral spinal cord interneuron differentiation GO:0021514 16 0.227
cerebellar granular layer development GO:0021681 13 0.225
mitral valve development GO:0003174 4 0.225
skeletal muscle cell differentiation GO:0035914 66 0.224
Mouse
response to organonitrogen compound GO:0010243 246 0.224
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.223
neuroendocrine cell differentiation GO:0061101 7 0.223
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.223
outflow tract morphogenesis GO:0003151 53 0.222
Mouse
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.221
Mouse
metanephric nephron development GO:0072210 34 0.219
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.219
regulation of protein complex assembly GO:0043254 83 0.218
Mouse
cell cycle arrest GO:0007050 37 0.218
glucose homeostasis GO:0042593 128 0.218
wnt signaling pathway involved in heart development GO:0003306 8 0.217
cellular homeostasis GO:0019725 240 0.216
alpha beta t cell differentiation GO:0046632 69 0.216
Mouse
neuron fate specification GO:0048665 30 0.216
cerebellum development GO:0021549 77 0.216
segment specification GO:0007379 15 0.216
midbrain development GO:0030901 35 0.215
axis elongation GO:0003401 30 0.215
Zebrafish
hemangioblast cell differentiation GO:0060217 1 0.215
positive regulation of neural precursor cell proliferation GO:2000179 42 0.214
cardiac chamber morphogenesis GO:0003206 93 0.214
Mouse
establishment of planar polarity GO:0001736 28 0.214
retina development in camera type eye GO:0060041 119 0.214
otic vesicle development GO:0071599 14 0.213
Mouse
atrial cardiac muscle tissue development GO:0003228 5 0.212
wnt signaling pathway GO:0016055 188 0.212
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.212
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.211
regulation of purine nucleotide catabolic process GO:0033121 122 0.211
mesenchymal cell proliferation GO:0010463 44 0.211
Mouse
collecting duct development GO:0072044 11 0.210
type b pancreatic cell proliferation GO:0044342 10 0.210
placenta development GO:0001890 140 0.209
Mouse
hindgut morphogenesis GO:0007442 7 0.208
Fly
mesodermal cell fate commitment GO:0001710 17 0.206
atrioventricular valve morphogenesis GO:0003181 13 0.205
Mouse
regulation of gliogenesis GO:0014013 50 0.205
paraxial mesoderm development GO:0048339 18 0.204
regulation of hormone levels GO:0010817 211 0.204
regulation of embryonic development GO:0045995 71 0.203
Zebrafish Mouse
pattern specification involved in metanephros development GO:0072268 4 0.202
mesonephric epithelium development GO:0072163 94 0.202
subpallium neuron fate commitment GO:0060163 2 0.202

T disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org