Mus musculus

70 known processes

Cd8a

CD8 antigen, alpha chain

(Aliases: Ly-2,Ly-B,Lyt-2,BB154331,Ly-35)

Cd8a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of calcium mediated signaling GO:0050848 19 0.796
lymphocyte differentiation GO:0030098 242 0.715
immune response activating signal transduction GO:0002757 116 0.704
immune effector process GO:0002252 321 0.678
leukocyte differentiation GO:0002521 342 0.618
defense response to other organism GO:0098542 197 0.618
regulation of lymphocyte activation GO:0051249 240 0.571
sequestering of calcium ion GO:0051208 18 0.563
positive regulation of calcium mediated signaling GO:0050850 15 0.563
regulation of cytokine production GO:0001817 266 0.563
alpha beta t cell proliferation GO:0046633 21 0.514
t cell proliferation GO:0042098 120 0.489
positive regulation of t cell activation GO:0050870 101 0.476
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.474
lymphocyte mediated immunity GO:0002449 139 0.471
t cell receptor signaling pathway GO:0050852 46 0.463
antigen receptor mediated signaling pathway GO:0050851 64 0.460
cation transport GO:0006812 399 0.449
regulation of lymphocyte anergy GO:0002911 4 0.442
adaptive immune response GO:0002250 155 0.413
regulation of t cell activation GO:0050863 170 0.404
regulation of cell activation GO:0050865 289 0.396
alpha beta t cell activation GO:0046631 91 0.395
t cell differentiation GO:0030217 174 0.390
cytokine production GO:0001816 319 0.383
leukocyte proliferation GO:0070661 172 0.380
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.374
neuron projection guidance GO:0097485 141 0.356
zinc ion homeostasis GO:0055069 10 0.352
cytokine mediated signaling pathway GO:0019221 115 0.349
defense response to bacterium GO:0042742 119 0.347
olfactory learning GO:0008355 2 0.339
release of sequestered calcium ion into cytosol GO:0051209 42 0.337
regulation of cellular amine metabolic process GO:0033238 20 0.327
positive regulation of lymphocyte activation GO:0051251 140 0.310
cellular amino acid metabolic process GO:0006520 103 0.308
regulation of cytokine secretion GO:0050707 61 0.299
cellular metal ion homeostasis GO:0006875 151 0.297
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.295
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.294
regulation of alpha beta t cell proliferation GO:0046640 18 0.284
divalent inorganic cation transport GO:0072511 178 0.280
modification of morphology or physiology of other organism GO:0035821 18 0.270
regulation of t cell anergy GO:0002667 4 0.267
t cell selection GO:0045058 34 0.262
regulation of protein transport GO:0051223 163 0.257
cytokine secretion GO:0050663 72 0.254
gamma delta t cell lineage commitment GO:0002365 1 0.247
metal ion homeostasis GO:0055065 189 0.246
positive regulation of t cell costimulation GO:2000525 2 0.242
myeloid leukocyte differentiation GO:0002573 119 0.240
positive regulation of cytokine secretion GO:0050715 41 0.239
peptidyl amino acid modification GO:0018193 336 0.233
regulation of cellular amino acid metabolic process GO:0006521 5 0.232
mature dendritic cell differentiation GO:0097029 3 0.230
thymic t cell selection GO:0045061 22 0.230
cation homeostasis GO:0055080 212 0.224
cellular ketone metabolic process GO:0042180 84 0.221
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.215
cell killing GO:0001906 67 0.211
divalent metal ion transport GO:0070838 172 0.198
second messenger mediated signaling GO:0019932 73 0.194
t cell costimulation GO:0031295 14 0.193
interspecies interaction between organisms GO:0044419 83 0.191
positive regulation of cellular amine metabolic process GO:0033240 5 0.190
regulation of cellular ketone metabolic process GO:0010565 66 0.189
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.186
t cell activation GO:0042110 289 0.184
t cell differentiation in thymus GO:0033077 77 0.182
calcium mediated signaling GO:0019722 46 0.181
positive regulation of cytokine production GO:0001819 174 0.177
leukocyte mediated immunity GO:0002443 174 0.177
negative regulation of homeostatic process GO:0032845 71 0.176
peptidyl tyrosine modification GO:0018212 145 0.175
maintenance of location GO:0051235 89 0.169
cellular divalent inorganic cation homeostasis GO:0072503 127 0.169
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.168
myeloid cell activation involved in immune response GO:0002275 34 0.167
interleukin 2 production GO:0032623 33 0.167
striated muscle tissue development GO:0014706 293 0.165
cellular homeostasis GO:0019725 240 0.161
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.156
neuron migration GO:0001764 122 0.155
positive regulation of immune effector process GO:0002699 107 0.154
positive regulation of lymphocyte proliferation GO:0050671 70 0.153
muscle tissue development GO:0060537 308 0.152
regulation of protein localization GO:0032880 231 0.150
negative regulation of immune system process GO:0002683 209 0.149
cellular ion homeostasis GO:0006873 165 0.147
positive regulation of leukocyte mediated immunity GO:0002705 70 0.145
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.145
cellular calcium ion homeostasis GO:0006874 119 0.142
extrinsic apoptotic signaling pathway GO:0097191 126 0.142
cdc42 protein signal transduction GO:0032488 0 0.142
regulation of ion transport GO:0043269 215 0.141
regulation of lymphocyte mediated immunity GO:0002706 84 0.141
viral process GO:0016032 41 0.139
positive regulation of leukocyte proliferation GO:0070665 73 0.138
regulation of t helper 2 cell cytokine production GO:2000551 3 0.138
positive t cell selection GO:0043368 23 0.138
sequestering of metal ion GO:0051238 19 0.136
calcium ion homeostasis GO:0055074 127 0.136
positive regulation of monocyte chemotaxis GO:0090026 2 0.135
endocytosis GO:0006897 168 0.134
regulation of t cell proliferation GO:0042129 92 0.130
positive regulation of lymphocyte anergy GO:0002913 4 0.128
regulation of protein kinase activity GO:0045859 232 0.128
hematopoietic stem cell migration GO:0035701 1 0.128
canonical wnt signaling pathway GO:0060070 130 0.127
negative regulation of cell proliferation GO:0008285 296 0.125
cell adhesion GO:0007155 329 0.125
regulation of immunological synapse formation GO:2000520 2 0.125
regulation of monocyte chemotaxis GO:0090025 3 0.124
wnt signaling pathway GO:0016055 188 0.123
germ cell development GO:0007281 185 0.119
response to growth factor GO:0070848 198 0.117
lymphocyte anergy GO:0002249 4 0.115
regulation of establishment of protein localization GO:0070201 181 0.114
myeloid leukocyte mediated immunity GO:0002444 42 0.114
divalent inorganic cation homeostasis GO:0072507 138 0.114
interleukin 12 secretion GO:0072610 3 0.114
positive regulation of cytokine biosynthetic process GO:0042108 40 0.113
positive regulation of interferon gamma production GO:0032729 39 0.111
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.111
modulation by virus of host process GO:0019054 2 0.109
regulation of angiogenesis GO:0045765 81 0.108
i kappab kinase nf kappab signaling GO:0007249 85 0.108
regulation of cytokine biosynthetic process GO:0042035 59 0.106
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.106
regulation of canonical wnt signaling pathway GO:0060828 82 0.106
lipoprotein biosynthetic process GO:0042158 33 0.106
regulation of leukocyte differentiation GO:1902105 159 0.105
eosinophil migration GO:0072677 3 0.103
regulation of interferon gamma production GO:0032649 57 0.098
exocytosis GO:0006887 121 0.097
negative t cell selection GO:0043383 13 0.097
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.096
regulation of wnt signaling pathway GO:0030111 123 0.096
cytosolic calcium ion homeostasis GO:0051480 70 0.094
cellular amine metabolic process GO:0044106 44 0.094
negative regulation of eosinophil degranulation GO:0043310 1 0.093
positive regulation of cell death GO:0010942 224 0.093
cell activation involved in immune response GO:0002263 126 0.092
regulation of inflammatory response GO:0050727 147 0.092
regulation of homeostatic process GO:0032844 182 0.091
b cell proliferation GO:0042100 53 0.090
regulation of calcium ion transport GO:0051924 69 0.090
regulation of transferase activity GO:0051338 263 0.089
regulation of cell motility GO:2000145 236 0.089
regulation of defense response GO:0031347 233 0.088
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.088
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.087
regulation of kinase activity GO:0043549 249 0.086
innate immune response GO:0045087 157 0.086
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.085
membrane organization GO:0061024 245 0.085
gliogenesis GO:0042063 141 0.084
innate immune response activating signal transduction GO:0002758 50 0.084
inner cell mass cell proliferation GO:0001833 15 0.084
positive regulation of cell activation GO:0050867 158 0.083
regulation of interleukin 8 secretion GO:2000482 2 0.083
epithelial tube morphogenesis GO:0060562 303 0.083
cytokine biosynthetic process GO:0042089 68 0.082
cell type specific apoptotic process GO:0097285 268 0.082
positive regulation of mast cell activation involved in immune response GO:0033008 10 0.081
regulation of protein secretion GO:0050708 82 0.080
skeletal muscle organ development GO:0060538 163 0.080
regulation of lymphocyte apoptotic process GO:0070228 41 0.079
regulation of adaptive immune response GO:0002819 90 0.079
positive regulation of b cell mediated immunity GO:0002714 26 0.079
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.078
regulation of mapk cascade GO:0043408 248 0.077
pallium development GO:0021543 120 0.077
detection of stimulus GO:0051606 84 0.076
organelle assembly GO:0070925 177 0.075
protein lipidation GO:0006497 28 0.075
regulation of leukocyte proliferation GO:0070663 121 0.075
interferon gamma production GO:0032609 67 0.073
cell fate commitment GO:0045165 210 0.073
regulation of interleukin 2 production GO:0032663 28 0.072
lymphocyte costimulation GO:0031294 15 0.072
myeloid leukocyte activation GO:0002274 83 0.072
lymphocyte apoptotic process GO:0070227 54 0.071
mitotic cell cycle process GO:1903047 159 0.071
branching morphogenesis of an epithelial tube GO:0048754 159 0.071
regulation of lymphocyte proliferation GO:0050670 117 0.071
regulation of map kinase activity GO:0043405 120 0.071
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.070
negative regulation of phosphorylation GO:0042326 166 0.070
response to transforming growth factor beta GO:0071559 88 0.070
t cell anergy GO:0002870 4 0.070
regulation of vesicle mediated transport GO:0060627 139 0.070
detection of yeast GO:0001879 2 0.070
chemotaxis GO:0006935 247 0.068
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.068
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.068
interleukin 8 production GO:0032637 4 0.067
multicellular organismal signaling GO:0035637 91 0.067
production of molecular mediator of immune response GO:0002440 103 0.067
detection of other organism GO:0098543 8 0.067
small gtpase mediated signal transduction GO:0007264 97 0.066
negative regulation of growth GO:0045926 99 0.066
negative regulation of defense response GO:0031348 77 0.066
positive regulation of cell killing GO:0031343 33 0.065
inflammatory response GO:0006954 244 0.065
stress activated protein kinase signaling cascade GO:0031098 81 0.064
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.063
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.063
leukocyte degranulation GO:0043299 27 0.063
regulation of cell projection organization GO:0031344 206 0.062
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.061
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.061
leukocyte activation involved in immune response GO:0002366 126 0.061
positive regulation of neuron differentiation GO:0045666 141 0.060
gland development GO:0048732 330 0.060
epithelial cell proliferation GO:0050673 174 0.060
lipoprotein metabolic process GO:0042157 43 0.060
regulation of phospholipase c activity GO:1900274 3 0.059
regulation of apoptotic signaling pathway GO:2001233 197 0.059
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.059
forebrain development GO:0030900 302 0.059
response to lipopolysaccharide GO:0032496 128 0.059
cytokine metabolic process GO:0042107 71 0.059
positive regulation of t cell proliferation GO:0042102 52 0.059
response to reactive oxygen species GO:0000302 56 0.058
immune response inhibiting signal transduction GO:0002765 4 0.058
positive regulation of t cell anergy GO:0002669 4 0.058
negative regulation of immune effector process GO:0002698 55 0.058
detection of fungus GO:0016046 2 0.058
regulation of endocytosis GO:0030100 69 0.058
interleukin 8 secretion GO:0072606 3 0.057
regulation of eosinophil degranulation GO:0043309 1 0.057
positive regulation of defense response GO:0031349 124 0.057
axonogenesis GO:0007409 274 0.057
protein secretion GO:0009306 111 0.057
regulation of cellular component biogenesis GO:0044087 181 0.057
positive regulation of secretion GO:0051047 130 0.056
negative regulation of synapse assembly GO:0051964 3 0.056
apoptotic signaling pathway GO:0097190 306 0.056
peptidyl tyrosine phosphorylation GO:0018108 143 0.056
positive regulation of phospholipase c activity GO:0010863 2 0.056
positive regulation of protein transport GO:0051222 93 0.056
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.055
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.054
regulation of t cell receptor signaling pathway GO:0050856 21 0.054
mitotic cell cycle GO:0000278 195 0.054
negative regulation of myeloid cell differentiation GO:0045638 38 0.054
osteoclast differentiation GO:0030316 62 0.053
regulation of interleukin 8 production GO:0032677 3 0.053
leukocyte mediated cytotoxicity GO:0001909 62 0.053
regulation of leukocyte mediated immunity GO:0002703 104 0.053
regulation of phagocytosis GO:0050764 33 0.052
blastocyst growth GO:0001832 23 0.052
regulation of epithelial cell proliferation GO:0050678 141 0.052
ensheathment of neurons GO:0007272 76 0.052
homeostasis of number of cells GO:0048872 210 0.052
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.052
activation of immune response GO:0002253 138 0.051
t cell mediated immunity GO:0002456 50 0.051
neuronal action potential GO:0019228 54 0.050
cellularization GO:0007349 1 0.050
lymphocyte proliferation GO:0046651 164 0.050
cellular lipid metabolic process GO:0044255 323 0.050
chemokine mediated signaling pathway GO:0070098 17 0.049
cellular zinc ion homeostasis GO:0006882 9 0.049
g protein coupled receptor signaling pathway GO:0007186 243 0.049
negative regulation of macrophage apoptotic process GO:2000110 3 0.049
gamma delta t cell activation GO:0046629 13 0.048
positive regulation of lipid metabolic process GO:0045834 40 0.048
neutrophil migration GO:1990266 37 0.048
cellular response to growth factor stimulus GO:0071363 197 0.047
morphogenesis of a branching epithelium GO:0061138 193 0.047
defense response to gram positive bacterium GO:0050830 50 0.047
somatic diversification of immune receptors GO:0002200 53 0.047
protein localization to membrane GO:0072657 108 0.047
regulation of intracellular transport GO:0032386 159 0.047
positive regulation of type ii hypersensitivity GO:0002894 4 0.047
negative regulation of t cell activation GO:0050868 65 0.047
regulation of muscle tissue development GO:1901861 97 0.047
calcium ion transport into cytosol GO:0060402 48 0.047
regulation of regulated secretory pathway GO:1903305 20 0.046
dendritic cell chemotaxis GO:0002407 7 0.046
myeloid cell differentiation GO:0030099 233 0.046
regulation of secretion by cell GO:1903530 249 0.046
regulation of myeloid cell differentiation GO:0045637 96 0.046
interleukin 4 production GO:0032633 24 0.046
cytoplasmic transport GO:0016482 234 0.046
endomembrane system organization GO:0010256 147 0.046
positive thymic t cell selection GO:0045059 13 0.046
cerebral cortex development GO:0021987 86 0.046
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.045
inflammatory cell apoptotic process GO:0006925 11 0.044
nitrogen compound transport GO:0071705 271 0.044
ventricular cardiac muscle tissue development GO:0003229 38 0.044
phospholipid metabolic process GO:0006644 87 0.043
negative regulation of leukocyte proliferation GO:0070664 46 0.042
response to molecule of bacterial origin GO:0002237 143 0.042
tumor necrosis factor production GO:0032640 50 0.042
regulation of neuron differentiation GO:0045664 281 0.042
negative regulation of intracellular signal transduction GO:1902532 167 0.042
tolerance induction to self antigen GO:0002513 4 0.042
fc receptor mediated inhibitory signaling pathway GO:0002774 1 0.041
regulation of secretion GO:0051046 274 0.041
regulation of cytoplasmic transport GO:1903649 112 0.041
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.041
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.041
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.041
interaction with symbiont GO:0051702 14 0.041
receptor mediated endocytosis GO:0006898 51 0.040
regulation of b cell mediated immunity GO:0002712 37 0.040
negative thymic t cell selection GO:0045060 12 0.040
positive regulation of kinase activity GO:0033674 155 0.039
growth involved in symbiotic interaction GO:0044110 23 0.039
cell fate specification GO:0001708 72 0.039
positive regulation of stress activated mapk cascade GO:0032874 48 0.039
positive regulation of leukocyte differentiation GO:1902107 86 0.039
angiogenesis GO:0001525 201 0.039
smoothened signaling pathway GO:0007224 105 0.039
axon guidance GO:0007411 141 0.038
myeloid cell apoptotic process GO:0033028 22 0.038
learning or memory GO:0007611 148 0.037
regulation of t cell costimulation GO:2000523 2 0.037
positive regulation of thymocyte migration GO:2000412 2 0.037
negative regulation of interleukin 8 production GO:0032717 1 0.037
positive regulation of eosinophil migration GO:2000418 2 0.037
regulation of myeloid leukocyte differentiation GO:0002761 58 0.037
microglial cell activation involved in immune response GO:0002282 1 0.037
monocyte extravasation GO:0035696 2 0.037
cardiac ventricle development GO:0003231 83 0.037
t helper 2 cell cytokine production GO:0035745 4 0.036
positive regulation of adaptive immune response GO:0002821 61 0.036
natural killer cell chemotaxis GO:0035747 1 0.036
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.036
sensory perception of pain GO:0019233 47 0.035
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.035
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.035
positive regulation of cell motility GO:2000147 116 0.035
negative regulation of interleukin 8 secretion GO:2000483 1 0.035
regulation of leukocyte apoptotic process GO:2000106 56 0.035
glycoprotein biosynthetic process GO:0009101 89 0.035
inner ear morphogenesis GO:0042472 101 0.035
immunoglobulin production GO:0002377 73 0.035
leukocyte apoptotic process GO:0071887 71 0.035
regulation of dendritic cell dendrite assembly GO:2000547 2 0.035
glial cell differentiation GO:0010001 131 0.034
heterocycle catabolic process GO:0046700 280 0.034
tissue remodeling GO:0048771 102 0.034
thymocyte migration GO:0072679 2 0.034
regulation of stress activated mapk cascade GO:0032872 69 0.034
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.034
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.034
regulation of actin filament based process GO:0032970 99 0.034
mature natural killer cell chemotaxis GO:0035782 1 0.033
tolerance induction GO:0002507 14 0.033
positive regulation of gliogenesis GO:0014015 27 0.033
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.033
detection of external stimulus GO:0009581 61 0.033
regulation of innate immune response GO:0045088 91 0.033
jak stat cascade GO:0007259 42 0.033
muscle cell development GO:0055001 133 0.033
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.033
response to tumor necrosis factor GO:0034612 26 0.032
detection of biotic stimulus GO:0009595 10 0.032
aromatic compound catabolic process GO:0019439 286 0.032
growth of symbiont in host GO:0044117 23 0.032
microtubule cytoskeleton organization GO:0000226 157 0.032
developmental maturation GO:0021700 193 0.032
striated muscle cell development GO:0055002 125 0.032
antigen processing and presentation GO:0019882 47 0.032
cardiac muscle tissue development GO:0048738 130 0.032
negative regulation of molecular function GO:0044092 258 0.031
transmission of nerve impulse GO:0019226 76 0.031
leukocyte migration GO:0050900 124 0.031
regulation of cell killing GO:0031341 40 0.031
regulation of immunoglobulin mediated immune response GO:0002889 37 0.031
negative regulation of lymphocyte activation GO:0051250 91 0.031
positive regulation of transferase activity GO:0051347 167 0.031
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.031
monocyte chemotaxis GO:0002548 5 0.031
neutrophil mediated immunity GO:0002446 19 0.030
positive regulation of innate immune response GO:0045089 80 0.030
phagocytosis GO:0006909 66 0.030
positive regulation of jun kinase activity GO:0043507 30 0.030
regulation of t cell extravasation GO:2000407 3 0.030
myeloid leukocyte migration GO:0097529 57 0.030
regulation of membrane potential GO:0042391 192 0.030
interleukin 1 beta secretion GO:0050702 16 0.030
positive regulation of cell adhesion GO:0045785 80 0.030
negative regulation of phosphate metabolic process GO:0045936 184 0.030
regulation of b cell apoptotic process GO:0002902 13 0.029
b cell activation GO:0042113 161 0.029
positive regulation of t helper 1 type immune response GO:0002827 12 0.029
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.029
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.029
alpha beta t cell differentiation GO:0046632 69 0.029
plasma membrane organization GO:0007009 90 0.029
regulation of eosinophil migration GO:2000416 2 0.029
regulation of mast cell proliferation GO:0070666 4 0.029
carbohydrate homeostasis GO:0033500 128 0.028
positive regulation of monocyte extravasation GO:2000439 1 0.028
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.028
positive regulation of endocytosis GO:0045807 42 0.028
stress activated mapk cascade GO:0051403 80 0.028
positive regulation of behavior GO:0048520 40 0.028
gamma delta t cell differentiation GO:0042492 11 0.028
mast cell activation GO:0045576 27 0.028
muscle contraction GO:0006936 101 0.028
regulation of b cell proliferation GO:0030888 39 0.028
positive regulation of dendritic cell apoptotic process GO:2000670 3 0.028
erk1 and erk2 cascade GO:0070371 77 0.028
positive regulation of cell projection organization GO:0031346 95 0.028
regulation of alpha beta t cell activation GO:0046634 53 0.028
regulation of chemotaxis GO:0050920 53 0.028
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.028
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.027
nuclear transport GO:0051169 139 0.027
immune response regulating signaling pathway GO:0002764 125 0.027
cytosolic calcium ion transport GO:0060401 48 0.027
regulation of cell migration GO:0030334 219 0.027
defense response to gram negative bacterium GO:0050829 28 0.027
t cell lineage commitment GO:0002360 13 0.027
synapse organization GO:0050808 125 0.027
positive regulation of intracellular transport GO:0032388 70 0.026
regulation of neuron death GO:1901214 134 0.026
regulation of anion transport GO:0044070 27 0.026
intrinsic apoptotic signaling pathway GO:0097193 132 0.026
positive regulation of protein secretion GO:0050714 52 0.026
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.026
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.026
astrocyte cell migration GO:0043615 3 0.026
positive regulation of neuron projection development GO:0010976 79 0.026
negative regulation of nervous system development GO:0051961 156 0.026
platelet degranulation GO:0002576 6 0.026
positive regulation of jnk cascade GO:0046330 46 0.026
spindle assembly involved in meiosis GO:0090306 4 0.026
regulation of response to wounding GO:1903034 189 0.026
negative regulation of cell development GO:0010721 169 0.026
positive regulation of nervous system development GO:0051962 221 0.025
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.025
positive regulation of organelle organization GO:0010638 128 0.025
b cell apoptotic process GO:0001783 19 0.025
cognition GO:0050890 149 0.025
microtubule based process GO:0007017 236 0.025
intracellular protein transport GO:0006886 204 0.025
cell fate determination involved in pattern specification GO:0060582 1 0.025
fc receptor mediated stimulatory signaling pathway GO:0002431 4 0.025
sensory organ morphogenesis GO:0090596 242 0.025
positive regulation of interleukin 2 biosynthetic process GO:0045086 8 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.025
t cell differentiation involved in immune response GO:0002292 30 0.025
positive regulation of cell development GO:0010720 237 0.025
somatic diversification of immunoglobulins GO:0016445 43 0.025
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.024
regulation of t cell differentiation GO:0045580 83 0.024
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.024
regulation of asymmetric cell division GO:0009786 4 0.024
positive regulation of podosome assembly GO:0071803 3 0.024
regulation of dendritic cell apoptotic process GO:2000668 3 0.024
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.024
response to oxidative stress GO:0006979 123 0.024
ossification GO:0001503 216 0.024
cellular chemical homeostasis GO:0055082 215 0.024
eosinophil mediated immunity GO:0002447 1 0.024
immune response inhibiting cell surface receptor signaling pathway GO:0002767 3 0.024
t helper 1 cell cytokine production GO:0035744 1 0.024
oligodendrocyte differentiation GO:0048709 53 0.024
morphogenesis of a branching structure GO:0001763 203 0.024
regulation of peptide transport GO:0090087 91 0.024
locomotory behavior GO:0007626 195 0.024
regulation of leukocyte degranulation GO:0043300 20 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
myeloid dendritic cell differentiation GO:0043011 16 0.023
regulation of mast cell activation GO:0033003 21 0.023
amine metabolic process GO:0009308 45 0.023
positive regulation of immunoglobulin production GO:0002639 28 0.023
disruption of cells of other organism GO:0044364 13 0.023
jnk cascade GO:0007254 72 0.023
positive regulation of neutrophil chemotaxis GO:0090023 12 0.023
protein localization to organelle GO:0033365 185 0.023
mammary gland morphogenesis GO:0060443 54 0.023
regulation of skeletal muscle fiber development GO:0048742 36 0.023
detection of molecule of bacterial origin GO:0032490 2 0.023
digestive system development GO:0055123 200 0.023
positive regulation of regulatory t cell differentiation GO:0045591 4 0.023
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.023
bundle of his development GO:0003166 4 0.023
hair follicle development GO:0001942 85 0.023
chondrocyte differentiation GO:0002062 72 0.023
cell recognition GO:0008037 83 0.023
glycoprotein metabolic process GO:0009100 116 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
positive regulation of phagocytosis GO:0050766 26 0.022
mammary gland epithelium development GO:0061180 65 0.022
positive regulation of tumor necrosis factor production GO:0032760 30 0.022
mammary gland duct morphogenesis GO:0060603 38 0.022
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.022
regulation of jnk cascade GO:0046328 62 0.022

Cd8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.025