Mus musculus

11 known processes

Pfdn2

prefoldin 2

(Aliases: ESTM27,W48336)

Pfdn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.244
positive regulation of protein modification process GO:0031401 299 0.221
protein refolding GO:0042026 1 0.172
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.131
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.127
nucleoside metabolic process GO:0009116 246 0.126
purine ribonucleotide metabolic process GO:0009150 290 0.124
rna splicing via transesterification reactions GO:0000375 43 0.119
positive regulation of protein phosphorylation GO:0001934 242 0.095
regulation of cellular amine metabolic process GO:0033238 20 0.087
positive regulation of dna templated transcription elongation GO:0032786 2 0.084
protein modification by small protein conjugation GO:0032446 187 0.074
cellular amino acid metabolic process GO:0006520 103 0.072
purine ribonucleoside metabolic process GO:0046128 241 0.072
macromolecule catabolic process GO:0009057 281 0.071
positive regulation of transferase activity GO:0051347 167 0.070
regulation of transferase activity GO:0051338 263 0.065
nitrogen compound transport GO:0071705 271 0.064
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
inorganic ion transmembrane transport GO:0098660 234 0.059
cation transport GO:0006812 399 0.058
rna processing GO:0006396 105 0.058
purine containing compound metabolic process GO:0072521 311 0.057
amine metabolic process GO:0009308 45 0.057
regulation of hydrolase activity GO:0051336 246 0.055
respiratory system development GO:0060541 190 0.055
organic cyclic compound catabolic process GO:1901361 295 0.055
regulation of organelle organization GO:0033043 289 0.053
cation transmembrane transport GO:0098655 266 0.052
purine nucleotide metabolic process GO:0006163 302 0.051
regulation of cellular catabolic process GO:0031329 242 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
cellular protein catabolic process GO:0044257 155 0.051
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.050
glycosyl compound metabolic process GO:1901657 246 0.050
positive regulation of mapk cascade GO:0043410 170 0.050
regulation of cellular component biogenesis GO:0044087 181 0.050
ribonucleotide metabolic process GO:0009259 291 0.048
positive regulation of protein kinase activity GO:0045860 144 0.048
cellular ketone metabolic process GO:0042180 84 0.047
purine nucleoside triphosphate catabolic process GO:0009146 203 0.046
nucleotide metabolic process GO:0009117 332 0.045
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.043
divalent inorganic cation transport GO:0072511 178 0.043
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.042
transmembrane transport GO:0055085 412 0.041
ribonucleoside triphosphate metabolic process GO:0009199 220 0.041
nucleotide catabolic process GO:0009166 217 0.041
protein ubiquitination GO:0016567 171 0.039
regulation of protein kinase activity GO:0045859 232 0.039
rna splicing GO:0008380 54 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
ribonucleoside metabolic process GO:0009119 245 0.038
dna metabolic process GO:0006259 303 0.038
peptidyl amino acid modification GO:0018193 336 0.037
carbohydrate derivative biosynthetic process GO:1901137 183 0.037
negative regulation of intracellular signal transduction GO:1902532 167 0.037
membrane organization GO:0061024 245 0.036
regulation of mrna metabolic process GO:1903311 43 0.036
aromatic compound catabolic process GO:0019439 286 0.035
ribonucleoside monophosphate catabolic process GO:0009158 57 0.035
modification dependent macromolecule catabolic process GO:0043632 133 0.035
regulation of cell cycle process GO:0010564 160 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
cellular response to dna damage stimulus GO:0006974 207 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
regulation of purine nucleotide catabolic process GO:0033121 122 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
inorganic cation transmembrane transport GO:0098662 207 0.033
ion transmembrane transport GO:0034220 361 0.033
divalent metal ion transport GO:0070838 172 0.033
positive regulation of organelle organization GO:0010638 128 0.033
nucleoside catabolic process GO:0009164 206 0.032
atp catabolic process GO:0006200 55 0.032
ribonucleotide biosynthetic process GO:0009260 59 0.032
mapk cascade GO:0000165 281 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
negative regulation of molecular function GO:0044092 258 0.031
cellular lipid metabolic process GO:0044255 323 0.030
cellular macromolecule catabolic process GO:0044265 206 0.030
mrna processing GO:0006397 63 0.029
signal transduction by p53 class mediator GO:0072331 51 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.028
negative regulation of cellular catabolic process GO:0031330 47 0.028
positive regulation of kinase activity GO:0033674 155 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.028
proteasomal protein catabolic process GO:0010498 98 0.026
purine containing compound biosynthetic process GO:0072522 70 0.026
negative regulation of cellular component organization GO:0051129 194 0.026
protein catabolic process GO:0030163 221 0.026
negative regulation of hydrolase activity GO:0051346 71 0.026
purine nucleoside catabolic process GO:0006152 205 0.026
endocytosis GO:0006897 168 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
regulation of inclusion body assembly GO:0090083 1 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
proton transport GO:0015992 35 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
purine nucleotide catabolic process GO:0006195 211 0.024
regulation of kinase activity GO:0043549 249 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
regulation of protein processing GO:0070613 96 0.024
mrna metabolic process GO:0016071 84 0.024
mitochondrial transport GO:0006839 36 0.024
nuclear export GO:0051168 34 0.023
heterocycle catabolic process GO:0046700 280 0.023
organophosphate catabolic process GO:0046434 232 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
nucleocytoplasmic transport GO:0006913 139 0.022
negative regulation of immune system process GO:0002683 209 0.022
negative regulation of purine nucleotide catabolic process GO:0033122 9 0.022
compound eye development GO:0048749 1 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
proteasome assembly GO:0043248 1 0.022
calcium ion transport GO:0006816 159 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
microtubule based process GO:0007017 236 0.021
adult behavior GO:0030534 135 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
nucleotide biosynthetic process GO:0009165 78 0.021
oocyte construction GO:0007308 2 0.021
organelle fusion GO:0048284 28 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
intracellular mrna localization GO:0008298 4 0.020
negative regulation of protein processing GO:0010955 79 0.020
nuclear transport GO:0051169 139 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
myeloid cell differentiation GO:0030099 233 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.019
apoptotic signaling pathway GO:0097190 306 0.019
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
purine nucleotide biosynthetic process GO:0006164 65 0.019
male sex differentiation GO:0046661 109 0.019
regulation of mrna splicing via spliceosome GO:0048024 32 0.019
negative regulation of phosphate metabolic process GO:0045936 184 0.019
regulation of translation GO:0006417 71 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.018
regulation of protein maturation GO:1903317 96 0.018
lung development GO:0030324 164 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
dna repair GO:0006281 107 0.018
developmental maturation GO:0021700 193 0.018
regulation of protein localization GO:0032880 231 0.018
endomembrane system organization GO:0010256 147 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
purine containing compound catabolic process GO:0072523 213 0.018
regulation of mrna processing GO:0050684 41 0.018
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
sensory perception GO:0007600 245 0.018
digestive system development GO:0055123 200 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
blastocyst development GO:0001824 80 0.018
cell maturation GO:0048469 127 0.018
blood vessel morphogenesis GO:0048514 285 0.017
cellular amine metabolic process GO:0044106 44 0.017
respiratory tube development GO:0030323 167 0.017
nucleoside triphosphate metabolic process GO:0009141 230 0.017
ribose phosphate biosynthetic process GO:0046390 59 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
mitochondrial fusion GO:0008053 9 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
regulation of proteolysis GO:0030162 164 0.017
atp metabolic process GO:0046034 75 0.017
ossification GO:0001503 216 0.017
cell adhesion GO:0007155 329 0.016
striated muscle myosin thick filament assembly GO:0071688 1 0.016
protein folding GO:0006457 28 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
palate development GO:0060021 76 0.016
regulation of membrane potential GO:0042391 192 0.016
synaptic transmission GO:0007268 329 0.016
response to organonitrogen compound GO:0010243 246 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
small molecule biosynthetic process GO:0044283 132 0.016
central nervous system neuron differentiation GO:0021953 162 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
skeletal system development GO:0001501 356 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
leukocyte differentiation GO:0002521 342 0.015
stem cell differentiation GO:0048863 268 0.015
regulation of protein catabolic process GO:0042176 108 0.015
ras protein signal transduction GO:0007265 77 0.015
regulation of protein ubiquitination GO:0031396 52 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
fertilization GO:0009566 127 0.015
erk1 and erk2 cascade GO:0070371 77 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
regulation of protein transport GO:0051223 163 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
rna catabolic process GO:0006401 29 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
oocyte axis specification GO:0007309 2 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
chromatin modification GO:0016568 187 0.014
nuclear division GO:0000280 158 0.014
b cell activation GO:0042113 161 0.014
regulation of homeostatic process GO:0032844 182 0.014
organelle assembly GO:0070925 177 0.014
locomotory behavior GO:0007626 195 0.014
protein import GO:0017038 101 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
development of primary sexual characteristics GO:0045137 143 0.014
angiogenesis GO:0001525 201 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
mitotic cell cycle process GO:1903047 159 0.013
regulation of cell motility GO:2000145 236 0.013
organelle localization GO:0051640 179 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
muscle cell differentiation GO:0042692 261 0.013
mrna splicing via spliceosome GO:0000398 43 0.013
regulation of neuron differentiation GO:0045664 281 0.013
cytoplasmic transport GO:0016482 234 0.013
negative regulation of proteolysis GO:0045861 74 0.013
positive regulation of cell death GO:0010942 224 0.013
protein localization to organelle GO:0033365 185 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
macromolecule methylation GO:0043414 120 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
regulation of mapk cascade GO:0043408 248 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
dephosphorylation GO:0016311 129 0.012
protein maturation GO:0051604 176 0.012
intracellular protein transport GO:0006886 204 0.012
cytokine production GO:0001816 319 0.012
regulation of intracellular transport GO:0032386 159 0.012
regulation of endocytosis GO:0030100 69 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
histone modification GO:0016570 159 0.012
regulation of cellular response to stress GO:0080135 159 0.012
protein processing GO:0016485 163 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
digestive tract development GO:0048565 190 0.012
response to heat GO:0009408 27 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
neural tube formation GO:0001841 108 0.012
immune response activating signal transduction GO:0002757 116 0.012
dendrite development GO:0016358 115 0.011
cation homeostasis GO:0055080 212 0.011
gtp catabolic process GO:0006184 143 0.011
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.011
nucleolus organization GO:0007000 5 0.011
regulation of ion transport GO:0043269 215 0.011
fatty acid metabolic process GO:0006631 121 0.011
leukocyte proliferation GO:0070661 172 0.011
wnt signaling pathway GO:0016055 188 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
male gamete generation GO:0048232 285 0.011
inter male aggressive behavior GO:0002121 3 0.011
t cell activation GO:0042110 289 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
organic acid biosynthetic process GO:0016053 86 0.011
synapse organization GO:0050808 125 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
regulation of protein binding GO:0043393 60 0.011
maintenance of location GO:0051235 89 0.011
prenylation GO:0097354 3 0.011
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.011
response to transforming growth factor beta GO:0071559 88 0.011
dna recombination GO:0006310 92 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
gland development GO:0048732 330 0.010
regulation of cell projection organization GO:0031344 206 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
establishment of organelle localization GO:0051656 122 0.010
glial cell differentiation GO:0010001 131 0.010
hematopoietic stem cell differentiation GO:0060218 8 0.010
response to peptide GO:1901652 136 0.010
phospholipid metabolic process GO:0006644 87 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.010
positive regulation of ubiquitin protein transferase activity GO:0051443 4 0.010
pole plasm assembly GO:0007315 2 0.010

Pfdn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.039
disease of anatomical entity DOID:7 0 0.039
musculoskeletal system disease DOID:17 0 0.039
muscle tissue disease DOID:66 0 0.039
central nervous system disease DOID:331 0 0.028
nervous system disease DOID:863 0 0.028
myopathy DOID:423 0 0.016
muscular dystrophy DOID:9884 0 0.013