|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
4 |
1.000
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.999
|
Fly |
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.999
|
Fly |
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.993
|
Fly |
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.991
|
Fly |
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.990
|
Fly |
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.984
|
Fly |
|
|
i kappab phosphorylation
|
GO:0007252 |
6 |
0.980
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.973
|
Fly |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.970
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.969
|
Fly |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.967
|
Fly |
|
|
negative regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902443 |
3 |
0.963
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.942
|
Fly |
|
|
negative regulation of necrotic cell death
|
GO:0060547 |
11 |
0.934
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.929
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.921
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.917
|
Mouse Fly |
|
|
regulation of necrotic cell death
|
GO:0010939 |
13 |
0.915
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
10 |
0.908
|
|
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.874
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.873
|
Fly |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.873
|
Mouse |
|
|
positive regulation of interferon beta production
|
GO:0032728 |
8 |
0.863
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.858
|
Mouse |
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.850
|
Fly |
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.848
|
Mouse |
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.836
|
Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.833
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.811
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.810
|
Mouse Fly |
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.806
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.771
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.759
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.758
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.752
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.751
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.748
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.739
|
Mouse Fly |
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.730
|
Mouse |
|
|
positive regulation of humoral immune response
|
GO:0002922 |
11 |
0.728
|
Fly |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.726
|
Mouse Fly |
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.723
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.722
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.713
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.703
|
|
|
|
negative regulation of necroptotic process
|
GO:0060546 |
9 |
0.696
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.690
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.685
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.684
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.679
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.669
|
Mouse |
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.640
|
Fly |
|
|
regulation of nik nf kappab signaling
|
GO:1901222 |
10 |
0.630
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.629
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.623
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.612
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.611
|
Fly |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.607
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.601
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.594
|
Mouse |
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.594
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.587
|
Human Rat |
|
|
protein import
|
GO:0017038 |
101 |
0.580
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.573
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.571
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.557
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.555
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.548
|
Fly |
|
|
positive regulation of sodium ion transport
|
GO:0010765 |
13 |
0.548
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.530
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.494
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.481
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.471
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.469
|
|
|
|
negative regulation of response to endoplasmic reticulum stress
|
GO:1903573 |
8 |
0.467
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.461
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.451
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.451
|
Mouse Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.444
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.444
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.439
|
Fly |
|
|
cytokine production
|
GO:0001816 |
319 |
0.436
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.422
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.422
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.421
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.411
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.405
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.400
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.398
|
Human |
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.394
|
Fly |
|
|
immune effector process
|
GO:0002252 |
321 |
0.394
|
Fly |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.393
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.382
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.382
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.380
|
Fly |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.374
|
|
|
|
positive regulation of nik nf kappab signaling
|
GO:1901224 |
7 |
0.371
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.364
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.362
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.361
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.358
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.355
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.352
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.350
|
Mouse Fly |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.350
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.343
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.342
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.339
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.338
|
Fly |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.337
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.336
|
Human Rat |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.335
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.334
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.327
|
Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.325
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.323
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.323
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.309
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.307
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.303
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.299
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.296
|
Fly |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.295
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.290
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.290
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.286
|
Rat |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.284
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.279
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.277
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.276
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.274
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.267
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.266
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.265
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.265
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.262
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.259
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.258
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.253
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.250
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.244
|
Mouse |
|
|
neural tube development
|
GO:0021915 |
160 |
0.243
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.242
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.242
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.240
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.238
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.236
|
Mouse |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.235
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.234
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.229
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.226
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.226
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.225
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.224
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.218
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.210
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.208
|
Human Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.206
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.205
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.205
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
3 |
0.204
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.204
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.203
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.202
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.202
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.202
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.201
|
|
|
|
ripoptosome assembly
|
GO:0097343 |
6 |
0.197
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.197
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.196
|
Human Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.195
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.195
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.192
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.191
|
Human Rat |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.189
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.189
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.189
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.187
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.186
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.186
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.186
|
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
3 |
0.185
|
Mouse |
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.184
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.183
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.181
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.179
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.178
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.178
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.176
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.176
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.175
|
|
|
|
organelle fusion
|
GO:0048284 |
28 |
0.172
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.171
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.169
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.168
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.167
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.167
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.165
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.165
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.165
|
Fly |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.163
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.163
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.161
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.160
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.159
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.158
|
Mouse |
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.158
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.158
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.153
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.151
|
|
|
|
positive regulation of response to biotic stimulus
|
GO:0002833 |
15 |
0.151
|
Fly |
|
|
regulation of cellular amide metabolic process
|
GO:0034248 |
10 |
0.151
|
Fly |
|
|
cell division
|
GO:0051301 |
120 |
0.148
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.147
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.145
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.144
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.143
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.143
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.142
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.141
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.141
|
|
|
|
negative regulation of reactive oxygen species metabolic process
|
GO:2000378 |
10 |
0.141
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.141
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.140
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.139
|
Fly |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.139
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.137
|
Human |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.136
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.135
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.134
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.133
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.132
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.132
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.132
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.131
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.130
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.128
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.128
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.125
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.125
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.125
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
27 |
0.125
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.125
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.124
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.124
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.122
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.122
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.121
|
Mouse |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.120
|
|
|
|
vacuole organization
|
GO:0007033 |
38 |
0.120
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
19 |
0.119
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.119
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.118
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.117
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.116
|
|
|
|
vesicle fusion
|
GO:0006906 |
16 |
0.116
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.115
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.115
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.115
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.114
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.114
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.112
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.111
|
Mouse |
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.111
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.110
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.110
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.110
|
|
|
|
interferon beta production
|
GO:0032608 |
16 |
0.110
|
Mouse |
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
15 |
0.110
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.109
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.109
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.108
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.106
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.106
|
Mouse |
|
|
lactation
|
GO:0007595 |
25 |
0.105
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.105
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.105
|
|
|
|
regulation of ripoptosome assembly involved in necroptotic process
|
GO:1902442 |
3 |
0.104
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.104
|
Human Fly |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.104
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.104
|
Rat |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.104
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.104
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.103
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.103
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.102
|
Rat |
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.102
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.101
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.100
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.100
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.099
|
|
|
|
positive regulation of ion transmembrane transporter activity
|
GO:0032414 |
15 |
0.098
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.098
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.097
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.097
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.097
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.097
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.095
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.094
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.094
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.094
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.093
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.092
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.092
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.092
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.092
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.091
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.091
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.090
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.090
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.089
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.089
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.089
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.088
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.088
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.087
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.087
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.086
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.086
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.086
|
|
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
17 |
0.086
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.086
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.086
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.085
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.085
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
15 |
0.085
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.085
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.085
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.085
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.083
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.082
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.082
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.082
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.081
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.081
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.081
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.081
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.080
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.080
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.079
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.079
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.078
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.078
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.078
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.077
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.077
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.076
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.076
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.075
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.075
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.075
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.075
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.075
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.075
|
Rat |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.075
|
|
|
|
membrane fusion
|
GO:0061025 |
38 |
0.075
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.074
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.073
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.073
|
|
|
|
segment specification
|
GO:0007379 |
15 |
0.073
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.073
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.072
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.072
|
|
|
|
regulation of cation channel activity
|
GO:2001257 |
22 |
0.072
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.071
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.071
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.071
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.071
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.071
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.071
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.070
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.070
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.070
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.069
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.069
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.068
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.068
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.068
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.068
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.068
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.068
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.067
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.067
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.066
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
46 |
0.066
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.066
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.066
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.066
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.066
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.065
|
Mouse |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.065
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.065
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.065
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.064
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.064
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.064
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.064
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.064
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.062
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.062
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.062
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.062
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.062
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.061
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.061
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.061
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.060
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.060
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.060
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.060
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.060
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.060
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.060
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.060
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.060
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.059
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.059
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.059
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.059
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.058
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.058
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.058
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.058
|
Mouse |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.058
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.057
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.057
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.057
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.057
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.057
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.057
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.057
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.056
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.056
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.056
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.055
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.055
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.055
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.055
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.055
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.054
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.054
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.054
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.054
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.054
|
|
|
|
protein homooligomerization
|
GO:0051260 |
43 |
0.054
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.054
|
|
|
|
pigment metabolic process
|
GO:0042440 |
32 |
0.053
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.053
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.053
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.053
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.053
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.053
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.053
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.052
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.052
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.052
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.051
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.051
|
Fly |
|
|
germinal center formation
|
GO:0002467 |
16 |
0.051
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.051
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.051
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.050
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.050
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.050
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.050
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.050
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.050
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.049
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.049
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.049
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.049
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.049
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.049
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.048
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.048
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.048
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
29 |
0.048
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.048
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.047
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.047
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.047
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.047
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.047
|
|
|
|
long term synaptic potentiation
|
GO:0060291 |
25 |
0.047
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.047
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.047
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.046
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.046
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.046
|
|
|
|
positive regulation of t cell cytokine production
|
GO:0002726 |
5 |
0.046
|
|
