Mus musculus

0 known processes

Cntrob

centrobin, centrosomal BRCA2 interacting protein

(Aliases: Lip8,9830165K03Rik)

Cntrob biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 102 0.315
cellular component assembly involved in morphogenesis GO:0010927 139 0.222
cilium assembly GO:0042384 81 0.172
male gamete generation GO:0048232 285 0.090
organelle assembly GO:0070925 177 0.088
embryonic organ morphogenesis GO:0048562 276 0.082
regionalization GO:0003002 337 0.082
cellular response to dna damage stimulus GO:0006974 207 0.078
dna metabolic process GO:0006259 303 0.073
mitotic cell cycle GO:0000278 195 0.067
sensory perception of sound GO:0007605 97 0.048
dna repair GO:0006281 107 0.047
multicellular organismal signaling GO:0035637 91 0.045
cell division GO:0051301 120 0.042
small gtpase mediated signal transduction GO:0007264 97 0.042
rho protein signal transduction GO:0007266 32 0.041
sensory perception GO:0007600 245 0.039
regulation of intracellular transport GO:0032386 159 0.039
camera type eye development GO:0043010 266 0.038
appendage development GO:0048736 166 0.038
exocytosis GO:0006887 121 0.038
microtubule based process GO:0007017 236 0.038
skeletal system development GO:0001501 356 0.037
chromatin organization GO:0006325 206 0.037
retina development in camera type eye GO:0060041 119 0.037
mechanoreceptor differentiation GO:0042490 67 0.036
cell maturation GO:0048469 127 0.036
regulation of cell cycle GO:0051726 281 0.035
determination of left right symmetry GO:0007368 80 0.035
telencephalon development GO:0021537 186 0.034
chromatin modification GO:0016568 187 0.033
axonogenesis GO:0007409 274 0.032
cytoplasmic transport GO:0016482 234 0.032
protein localization to organelle GO:0033365 185 0.032
posttranscriptional regulation of gene expression GO:0010608 155 0.032
positive regulation of programmed cell death GO:0043068 218 0.032
neural precursor cell proliferation GO:0061351 121 0.031
regulation of protein localization GO:0032880 231 0.031
female gamete generation GO:0007292 74 0.030
germ cell development GO:0007281 185 0.030
embryonic skeletal system development GO:0048706 120 0.030
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.028
limb morphogenesis GO:0035108 149 0.028
spermatogenesis GO:0007283 284 0.028
determination of left right asymmetry in nervous system GO:0035545 1 0.027
gland development GO:0048732 330 0.027
oogenesis GO:0048477 56 0.027
smoothened signaling pathway GO:0007224 105 0.027
embryonic appendage morphogenesis GO:0035113 126 0.026
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.026
cell fate commitment GO:0045165 210 0.026
ear development GO:0043583 200 0.026
ear morphogenesis GO:0042471 118 0.025
immune effector process GO:0002252 321 0.025
digestive system development GO:0055123 200 0.025
nitrogen compound transport GO:0071705 271 0.024
glycosyl compound metabolic process GO:1901657 246 0.024
embryonic limb morphogenesis GO:0030326 126 0.024
sensory system development GO:0048880 3 0.024
organelle fission GO:0048285 170 0.024
respiratory system development GO:0060541 190 0.024
hindbrain development GO:0030902 128 0.024
regulation of cell cycle process GO:0010564 160 0.023
meiotic nuclear division GO:0007126 115 0.023
negative regulation of dendrite development GO:2000171 9 0.023
maintenance of location GO:0051235 89 0.023
fertilization GO:0009566 127 0.023
sensory perception of mechanical stimulus GO:0050954 107 0.022
urogenital system development GO:0001655 261 0.022
regulation of neuron differentiation GO:0045664 281 0.022
regulation of binding GO:0051098 111 0.022
dendrite development GO:0016358 115 0.022
metaphase plate congression GO:0051310 2 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
protein processing GO:0016485 163 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
appendage morphogenesis GO:0035107 149 0.021
negative regulation of cell development GO:0010721 169 0.021
peptide secretion GO:0002790 114 0.021
forebrain development GO:0030900 302 0.021
lymphocyte differentiation GO:0030098 242 0.021
b cell activation GO:0042113 161 0.020
rhodopsin mediated signaling pathway GO:0016056 4 0.020
stem cell maintenance GO:0019827 130 0.020
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.019
development of primary male sexual characteristics GO:0046546 88 0.019
protein citrullination GO:0018101 2 0.019
neural tube closure GO:0001843 90 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
skeletal system morphogenesis GO:0048705 203 0.019
heterocycle catabolic process GO:0046700 280 0.018
meiotic cell cycle GO:0051321 122 0.018
gtp catabolic process GO:0006184 143 0.018
cation transport GO:0006812 399 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
male meiosis GO:0007140 37 0.018
rna splicing GO:0008380 54 0.018
transmission of nerve impulse GO:0019226 76 0.018
cellular amine metabolic process GO:0044106 44 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
circadian rhythm GO:0007623 114 0.018
leukocyte migration GO:0050900 124 0.018
adult locomotory behavior GO:0008344 91 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.017
regulation of stem cell proliferation GO:0072091 78 0.017
inner ear receptor cell differentiation GO:0060113 61 0.017
meiotic chromosome segregation GO:0045132 19 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
cell recognition GO:0008037 83 0.017
epidermis development GO:0008544 187 0.017
nuclear division GO:0000280 158 0.017
response to radiation GO:0009314 165 0.017
multicellular organism growth GO:0035264 161 0.017
epithalamus development GO:0021538 2 0.017
stem cell development GO:0048864 219 0.017
ras protein signal transduction GO:0007265 77 0.017
protein import into nucleus GO:0006606 95 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
leukocyte differentiation GO:0002521 342 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
nuclear transport GO:0051169 139 0.016
localization within membrane GO:0051668 4 0.016
regulation of ras gtpase activity GO:0032318 88 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
single organism nuclear import GO:1902593 95 0.016
skin development GO:0043588 220 0.016
positive regulation of transferase activity GO:0051347 167 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
oocyte construction GO:0007308 2 0.016
aromatic compound catabolic process GO:0019439 286 0.016
sensory organ morphogenesis GO:0090596 242 0.016
limb development GO:0060173 166 0.016
regulation of nucleocytoplasmic transport GO:0046822 73 0.016
developmental maturation GO:0021700 193 0.016
positive regulation of nervous system development GO:0051962 221 0.016
cerebellum development GO:0021549 77 0.016
epithelial tube morphogenesis GO:0060562 303 0.015
positive regulation of cell development GO:0010720 237 0.015
regulation of mrna splicing via spliceosome GO:0048024 32 0.015
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.015
protein import GO:0017038 101 0.015
microtubule organizing center organization GO:0031023 28 0.015
regulation of stem cell differentiation GO:2000736 50 0.015
thick ascending limb development GO:0072023 2 0.015
meiosis i GO:0007127 60 0.015
digestive tract development GO:0048565 190 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
nucleoside catabolic process GO:0009164 206 0.015
cerebral cortex development GO:0021987 86 0.015
transmembrane transport GO:0055085 412 0.015
leukocyte mediated immunity GO:0002443 174 0.015
mitotic cell cycle process GO:1903047 159 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
neuroblast differentiation GO:0014016 2 0.014
development of primary sexual characteristics GO:0045137 143 0.014
regulation of neural precursor cell proliferation GO:2000177 70 0.014
spermatid development GO:0007286 108 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
inner ear morphogenesis GO:0042472 101 0.014
actin cytoskeleton organization GO:0030036 220 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
heart morphogenesis GO:0003007 178 0.014
kidney development GO:0001822 213 0.014
establishment of organelle localization GO:0051656 122 0.014
protein maturation GO:0051604 176 0.014
adult behavior GO:0030534 135 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
synapsis GO:0007129 34 0.014
hair cell differentiation GO:0035315 40 0.014
regulation of asymmetric cell division GO:0009786 4 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
cellular amino acid metabolic process GO:0006520 103 0.014
regulation of chromosome organization GO:0033044 83 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of hormone secretion GO:0046883 88 0.014
ion transmembrane transport GO:0034220 361 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
b cell differentiation GO:0030183 78 0.014
mrna metabolic process GO:0016071 84 0.014
rac protein signal transduction GO:0016601 13 0.014
cation transmembrane transport GO:0098655 266 0.014
neurohypophysis development GO:0021985 2 0.014
gastrulation GO:0007369 116 0.014
rhythmic process GO:0048511 174 0.014
oocyte axis specification GO:0007309 2 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of gtp catabolic process GO:0033124 113 0.013
regulation of hydrolase activity GO:0051336 246 0.013
cell fate determination involved in pattern specification GO:0060582 1 0.013
blastocyst growth GO:0001832 23 0.013
muscle cell differentiation GO:0042692 261 0.013
nuclear import GO:0051170 95 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
endocytosis GO:0006897 168 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
mrna splicing via spliceosome GO:0000398 43 0.013
negative regulation of cell cycle GO:0045786 123 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
microtubule based movement GO:0007018 84 0.013
regulation of peptide secretion GO:0002791 77 0.013
regulation of protein import into nucleus GO:0042306 52 0.013
protein targeting GO:0006605 143 0.013
gonad development GO:0008406 141 0.013
asymmetric stem cell division GO:0098722 3 0.013
organophosphate catabolic process GO:0046434 232 0.013
compound eye development GO:0048749 1 0.013
rna splicing via transesterification reactions GO:0000375 43 0.013
regulation of cell projection organization GO:0031344 206 0.013
cellular homeostasis GO:0019725 240 0.013
spindle assembly involved in female meiosis GO:0007056 3 0.012
neuron migration GO:0001764 122 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
negative regulation of nervous system development GO:0051961 156 0.012
digestive tract morphogenesis GO:0048546 147 0.012
regulation of rna splicing GO:0043484 37 0.012
inner cell mass cell fate commitment GO:0001827 2 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
cell fate specification GO:0001708 72 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
cell type specific apoptotic process GO:0097285 268 0.012
signal transduction in absence of ligand GO:0038034 55 0.012
insulin secretion GO:0030073 89 0.012
positive regulation of cell cycle GO:0045787 92 0.012
tube formation GO:0035148 140 0.012
cilium movement GO:0003341 28 0.012
maintenance of apical basal cell polarity GO:0035090 3 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
regulation of cell activation GO:0050865 289 0.012
regulation of protein transport GO:0051223 163 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
cell cycle g2 m phase transition GO:0044839 20 0.012
response to transforming growth factor beta GO:0071559 88 0.012
regulation of organelle organization GO:0033043 289 0.012
glucose homeostasis GO:0042593 128 0.012
embryonic digit morphogenesis GO:0042733 56 0.012
regulation of cellular amino acid metabolic process GO:0006521 5 0.012
rna stabilization GO:0043489 9 0.012
skeletal muscle organ development GO:0060538 163 0.012
gonad morphogenesis GO:0035262 1 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.012
dna conformation change GO:0071103 37 0.012
proprioception GO:0019230 4 0.012
ribonucleoside catabolic process GO:0042454 206 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
nucleoside metabolic process GO:0009116 246 0.011
single fertilization GO:0007338 82 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
protein localization to nucleus GO:0034504 121 0.011
striated muscle tissue development GO:0014706 293 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
leukocyte proliferation GO:0070661 172 0.011
stem cell differentiation GO:0048863 268 0.011
chemotaxis GO:0006935 247 0.011
actomyosin structure organization GO:0031032 56 0.011
calcium ion dependent exocytosis GO:0017156 35 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
mrna processing GO:0006397 63 0.011
male gonad development GO:0008584 88 0.011
blood vessel morphogenesis GO:0048514 285 0.011
muscle tissue development GO:0060537 308 0.011
macromolecule deacylation GO:0098732 37 0.011
ectoderm formation GO:0001705 3 0.011
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.011
epithelial cell proliferation GO:0050673 174 0.011
cellular ketone metabolic process GO:0042180 84 0.011
purine containing compound catabolic process GO:0072523 213 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
response to growth factor GO:0070848 198 0.011
cell activation involved in immune response GO:0002263 126 0.011
spinal cord development GO:0021510 81 0.011
amine metabolic process GO:0009308 45 0.011
neuronal action potential GO:0019228 54 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
ascending thin limb development GO:0072021 2 0.011
hormone secretion GO:0046879 128 0.011
cell cycle checkpoint GO:0000075 47 0.010
cardiac chamber development GO:0003205 108 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
regulation of mrna metabolic process GO:1903311 43 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
organic anion transport GO:0015711 137 0.010
myeloid cell differentiation GO:0030099 233 0.010
cranial nerve development GO:0021545 41 0.010
macromolecule methylation GO:0043414 120 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
carbohydrate homeostasis GO:0033500 128 0.010
ventricular compact myocardium morphogenesis GO:0003223 2 0.010
regulation of exocytosis GO:0017157 61 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.010
metanephric ascending thin limb development GO:0072218 2 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.010
heterochromatin organization GO:0070828 4 0.010
anatomical structure homeostasis GO:0060249 145 0.010
regulation of translation GO:0006417 71 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.010
positive regulation of organelle organization GO:0010638 128 0.010

Cntrob disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034
immune system disease DOID:2914 0 0.029
disease of anatomical entity DOID:7 0 0.029
large intestine cancer DOID:5672 0 0.024
gastrointestinal system cancer DOID:3119 0 0.024
intestinal cancer DOID:10155 0 0.024
congenital hypoplastic anemia DOID:1342 0 0.023
aplastic anemia DOID:12449 0 0.023
bone marrow disease DOID:4961 0 0.023
anemia DOID:2355 0 0.023
hematopoietic system disease DOID:74 0 0.023
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.013
colorectal cancer DOID:9256 0 0.012