Mus musculus

0 known processes

Tox2

TOX high mobility group box family member 2

(Aliases: AI851523,BI987407,Gcx1,RxHMG1,AV026525)

Tox2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aromatic compound catabolic process GO:0019439 286 0.087
cellular amino acid metabolic process GO:0006520 103 0.072
organic cyclic compound catabolic process GO:1901361 295 0.063
purine nucleoside catabolic process GO:0006152 205 0.060
male gamete generation GO:0048232 285 0.060
purine ribonucleoside metabolic process GO:0046128 241 0.058
carbohydrate metabolic process GO:0005975 230 0.056
purine containing compound metabolic process GO:0072521 311 0.052
cellular amine metabolic process GO:0044106 44 0.052
small gtpase mediated signal transduction GO:0007264 97 0.051
ribonucleotide metabolic process GO:0009259 291 0.050
organonitrogen compound catabolic process GO:1901565 264 0.050
amine metabolic process GO:0009308 45 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
purine nucleotide metabolic process GO:0006163 302 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.047
ras protein signal transduction GO:0007265 77 0.046
purine nucleoside metabolic process GO:0042278 241 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
regulation of cellular catabolic process GO:0031329 242 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.043
heterocycle catabolic process GO:0046700 280 0.043
cytokine production GO:0001816 319 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.041
negative regulation of protein metabolic process GO:0051248 282 0.040
regulation of nucleoside metabolic process GO:0009118 130 0.040
nucleoside triphosphate metabolic process GO:0009141 230 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
protein modification by small protein conjugation GO:0032446 187 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
ribonucleotide catabolic process GO:0009261 208 0.039
muscle cell differentiation GO:0042692 261 0.039
digestive system development GO:0055123 200 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
ribonucleoside triphosphate catabolic process GO:0009203 199 0.037
regulation of hydrolase activity GO:0051336 246 0.037
leukocyte differentiation GO:0002521 342 0.037
glycosyl compound metabolic process GO:1901657 246 0.037
synaptic transmission GO:0007268 329 0.037
nucleotide metabolic process GO:0009117 332 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
regulation of cell projection organization GO:0031344 206 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.035
muscle tissue development GO:0060537 308 0.035
regulation of organelle organization GO:0033043 289 0.034
protein ubiquitination GO:0016567 171 0.033
nucleoside metabolic process GO:0009116 246 0.033
cellular ketone metabolic process GO:0042180 84 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.033
response to organonitrogen compound GO:0010243 246 0.033
sensory system development GO:0048880 3 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.031
regulation of secretion by cell GO:1903530 249 0.030
striated muscle tissue development GO:0014706 293 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.029
lymphocyte differentiation GO:0030098 242 0.029
skin development GO:0043588 220 0.029
regulation of membrane potential GO:0042391 192 0.029
negative regulation of intracellular signal transduction GO:1902532 167 0.029
regulation of cytokine production GO:0001817 266 0.029
guanosine containing compound metabolic process GO:1901068 144 0.028
chemotaxis GO:0006935 247 0.028
nucleotide catabolic process GO:0009166 217 0.028
gtp metabolic process GO:0046039 144 0.028
purine nucleotide catabolic process GO:0006195 211 0.027
cell type specific apoptotic process GO:0097285 268 0.027
chromatin organization GO:0006325 206 0.027
spermatogenesis GO:0007283 284 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
macromolecule catabolic process GO:0009057 281 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
membrane organization GO:0061024 245 0.026
guanosine containing compound catabolic process GO:1901069 144 0.026
regulation of secretion GO:0051046 274 0.026
sensory perception GO:0007600 245 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
positive regulation of nervous system development GO:0051962 221 0.026
organophosphate catabolic process GO:0046434 232 0.026
cell adhesion GO:0007155 329 0.025
camera type eye development GO:0043010 266 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
ossification GO:0001503 216 0.025
regulation of nucleotide metabolic process GO:0006140 169 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
nucleoside catabolic process GO:0009164 206 0.024
organelle fission GO:0048285 170 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
blood circulation GO:0008015 195 0.023
cation homeostasis GO:0055080 212 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
digestive tract development GO:0048565 190 0.023
metal ion homeostasis GO:0055065 189 0.023
purine containing compound catabolic process GO:0072523 213 0.023
extracellular matrix organization GO:0030198 147 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
positive regulation of cell development GO:0010720 237 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
epidermis development GO:0008544 187 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
epithelial cell proliferation GO:0050673 174 0.022
mapk cascade GO:0000165 281 0.022
cell maturation GO:0048469 127 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
cation transport GO:0006812 399 0.022
cellular response to lipid GO:0071396 145 0.022
regulation of protein kinase activity GO:0045859 232 0.022
extracellular structure organization GO:0043062 148 0.022
pallium development GO:0021543 120 0.022
protein secretion GO:0009306 111 0.021
compound eye development GO:0048749 1 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
digestive tract morphogenesis GO:0048546 147 0.021
germ cell development GO:0007281 185 0.021
protein maturation GO:0051604 176 0.021
exocytosis GO:0006887 121 0.021
stem cell development GO:0048864 219 0.021
microtubule based process GO:0007017 236 0.021
organelle assembly GO:0070925 177 0.021
protein processing GO:0016485 163 0.021
regulation of anatomical structure size GO:0090066 178 0.021
regulation of neuron projection development GO:0010975 169 0.021
divalent inorganic cation transport GO:0072511 178 0.021
regulation of hormone levels GO:0010817 211 0.020
gland development GO:0048732 330 0.020
telencephalon development GO:0021537 186 0.020
actin cytoskeleton organization GO:0030036 220 0.020
developmental maturation GO:0021700 193 0.020
neuron projection guidance GO:0097485 141 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
endocytosis GO:0006897 168 0.020
regulation of establishment of protein localization GO:0070201 181 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
peptidyl amino acid modification GO:0018193 336 0.019
cellular chemical homeostasis GO:0055082 215 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
respiratory system development GO:0060541 190 0.019
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
covalent chromatin modification GO:0016569 163 0.019
negative regulation of cellular component organization GO:0051129 194 0.018
regulation of transferase activity GO:0051338 263 0.018
plasma membrane organization GO:0007009 90 0.018
regulation of ras gtpase activity GO:0032318 88 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
myeloid cell differentiation GO:0030099 233 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
response to growth factor GO:0070848 198 0.018
regulation of cell activation GO:0050865 289 0.018
connective tissue development GO:0061448 179 0.018
positive regulation of cell death GO:0010942 224 0.018
regionalization GO:0003002 337 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.018
dna metabolic process GO:0006259 303 0.018
regulation of protein localization GO:0032880 231 0.018
axonogenesis GO:0007409 274 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
negative regulation of molecular function GO:0044092 258 0.017
tube formation GO:0035148 140 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
regulation of protein transport GO:0051223 163 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
calcium ion transport GO:0006816 159 0.017
forebrain development GO:0030900 302 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
inflammatory response GO:0006954 244 0.017
skeletal system development GO:0001501 356 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
cardiac muscle tissue development GO:0048738 130 0.017
epithelial cell development GO:0002064 159 0.017
endomembrane system organization GO:0010256 147 0.017
regulation of cell motility GO:2000145 236 0.017
blood vessel morphogenesis GO:0048514 285 0.017
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.017
regulation of mapk cascade GO:0043408 248 0.017
nitrogen compound transport GO:0071705 271 0.017
hexose metabolic process GO:0019318 98 0.017
stem cell maintenance GO:0019827 130 0.017
interleukin 8 production GO:0032637 4 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
pharynx development GO:0060465 1 0.017
apoptotic signaling pathway GO:0097190 306 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of neuron differentiation GO:0045664 281 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
cellular homeostasis GO:0019725 240 0.016
positive regulation of growth GO:0045927 104 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
chromatin modification GO:0016568 187 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of ion transport GO:0043269 215 0.016
wound healing GO:0042060 157 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
cell fate commitment GO:0045165 210 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.016
rhythmic process GO:0048511 174 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
immune effector process GO:0002252 321 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
positive regulation of protein modification process GO:0031401 299 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
oxidation reduction process GO:0055114 342 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
regulation of exocytosis GO:0017157 61 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
transmission of nerve impulse GO:0019226 76 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
negative regulation of protein modification process GO:0031400 163 0.015
regulation of body fluid levels GO:0050878 162 0.015
neuron migration GO:0001764 122 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
organelle localization GO:0051640 179 0.015
feeding behavior GO:0007631 62 0.015
positive regulation of organelle organization GO:0010638 128 0.015
meiotic nuclear division GO:0007126 115 0.015
stem cell differentiation GO:0048863 268 0.015
blastocyst development GO:0001824 80 0.015
fat cell differentiation GO:0045444 160 0.015
cellular response to organonitrogen compound GO:0071417 145 0.014
cellular response to molecule of bacterial origin GO:0071219 83 0.014
regulation of cell adhesion GO:0030155 154 0.014
fertilization GO:0009566 127 0.014
mitotic cell cycle GO:0000278 195 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
glucose homeostasis GO:0042593 128 0.014
gtp catabolic process GO:0006184 143 0.014
positive regulation of secretion GO:0051047 130 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of intracellular transport GO:0032386 159 0.014
skeletal muscle organ development GO:0060538 163 0.014
posttranscriptional gene silencing by rna GO:0035194 10 0.014
gene silencing by rna GO:0031047 19 0.014
cognition GO:0050890 149 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
nuclear division GO:0000280 158 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
response to oxygen levels GO:0070482 62 0.014
detection of molecule of bacterial origin GO:0032490 2 0.014
multicellular organism growth GO:0035264 161 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of protein maturation GO:1903317 96 0.014
t cell activation GO:0042110 289 0.014
neuronal action potential GO:0019228 54 0.013
gastrulation GO:0007369 116 0.013
regulation of cell cycle process GO:0010564 160 0.013
pole plasm assembly GO:0007315 2 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
positive regulation of cytokine production GO:0001819 174 0.013
urogenital system development GO:0001655 261 0.013
cellular ion homeostasis GO:0006873 165 0.013
muscle cell development GO:0055001 133 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
sensory organ morphogenesis GO:0090596 242 0.013
positive regulation of epithelial cell proliferation GO:0050679 68 0.013
embryonic placenta development GO:0001892 98 0.013
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.013
regulation of protein processing GO:0070613 96 0.013
mrna metabolic process GO:0016071 84 0.013
response to lipopolysaccharide GO:0032496 128 0.013
calcium ion homeostasis GO:0055074 127 0.013
spermatid differentiation GO:0048515 115 0.013
bmp signaling pathway GO:0030509 93 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
cellular protein catabolic process GO:0044257 155 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
rho protein signal transduction GO:0007266 32 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
segmentation GO:0035282 93 0.012
neural tube development GO:0021915 160 0.012
divalent metal ion transport GO:0070838 172 0.012
mesoderm development GO:0007498 100 0.012
histone modification GO:0016570 159 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
intracellular protein transport GO:0006886 204 0.012
placenta development GO:0001890 140 0.012
regulation of cell migration GO:0030334 219 0.012
negative regulation of transferase activity GO:0051348 85 0.012
maintenance of location GO:0051235 89 0.012
response to acid chemical GO:0001101 111 0.012
epithelial tube formation GO:0072175 130 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
multicellular organismal response to stress GO:0033555 62 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
protein catabolic process GO:0030163 221 0.012
monosaccharide metabolic process GO:0005996 106 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
respiratory tube development GO:0030323 167 0.012
neuron death GO:0070997 154 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of kinase activity GO:0043549 249 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
muscle system process GO:0003012 141 0.012
vesicle localization GO:0051648 86 0.012
second messenger mediated signaling GO:0019932 73 0.012
axon guidance GO:0007411 141 0.012
bone development GO:0060348 120 0.012
transcription from rna polymerase iii promoter GO:0006383 3 0.012
skeletal system morphogenesis GO:0048705 203 0.012
single organism cell adhesion GO:0098602 156 0.012
synapse organization GO:0050808 125 0.012
lateral inhibition GO:0046331 1 0.012
rna processing GO:0006396 105 0.011
meiotic cell cycle GO:0051321 122 0.011
response to insulin GO:0032868 100 0.011
meiosis i GO:0007127 60 0.011
mitochondrion organization GO:0007005 134 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
glycerolipid metabolic process GO:0046486 122 0.011
tube closure GO:0060606 91 0.011
neural tube closure GO:0001843 90 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
negative regulation of protein maturation GO:1903318 79 0.011
regulation of cell growth GO:0001558 91 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
rna interference GO:0016246 2 0.011
transmembrane transport GO:0055085 412 0.011
dendrite development GO:0016358 115 0.011
glucose metabolic process GO:0006006 92 0.011
adult behavior GO:0030534 135 0.011
response to peptide GO:1901652 136 0.011
ameboidal type cell migration GO:0001667 128 0.011
locomotory behavior GO:0007626 195 0.011
ear development GO:0043583 200 0.011
protein localization to organelle GO:0033365 185 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
hormone secretion GO:0046879 128 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
negative regulation of cell cycle GO:0045786 123 0.011
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.011
spermatid development GO:0007286 108 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of chromosome organization GO:0033044 83 0.011
mrna processing GO:0006397 63 0.011
regulation of myeloid cell differentiation GO:0045637 96 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
neural tube formation GO:0001841 108 0.011
negative regulation of cell development GO:0010721 169 0.010
synaptic vesicle localization GO:0097479 59 0.010
regulation of protein complex assembly GO:0043254 83 0.010
ventricular compact myocardium morphogenesis GO:0003223 2 0.010
inter male aggressive behavior GO:0002121 3 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
cytokine secretion GO:0050663 72 0.010
cardiocyte differentiation GO:0035051 87 0.010
equilibrioception GO:0050957 3 0.010
ventricular cardiac muscle tissue development GO:0003229 38 0.010
mitotic nuclear division GO:0007067 48 0.010
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.010
regulation of embryonic development GO:0045995 71 0.010
homeostasis of number of cells GO:0048872 210 0.010
cardiac chamber development GO:0003205 108 0.010
negative regulation of camp mediated signaling GO:0043951 3 0.010
regulation of organ morphogenesis GO:2000027 144 0.010
sequestering of calcium ion GO:0051208 18 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
cardiac ventricle development GO:0003231 83 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
neuron apoptotic process GO:0051402 142 0.010
negative regulation of phosphorus metabolic process GO:0010563 184 0.010
regulation of cytoskeleton organization GO:0051493 122 0.010
posttranscriptional gene silencing GO:0016441 10 0.010
striated muscle cell development GO:0055002 125 0.010
negative regulation of protein catabolic process GO:0042177 36 0.010
negative regulation of kinase activity GO:0033673 81 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
response to organic cyclic compound GO:0014070 198 0.010

Tox2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
central nervous system disease DOID:331 0 0.013
organ system cancer DOID:0050686 0 0.012