|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.994
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.992
|
Human |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.991
|
Human |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.984
|
Human |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.982
|
Human |
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
4 |
0.977
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.971
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.965
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.962
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.960
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.958
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.957
|
Human |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.954
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.946
|
Human |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.938
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.935
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.931
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.915
|
Human |
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.914
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.907
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.905
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.904
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.903
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.903
|
Human |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.891
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.890
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.880
|
Human |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.878
|
Human |
|
|
keratinocyte development
|
GO:0003334 |
10 |
0.870
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.864
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.857
|
Human |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.841
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.840
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.835
|
Human |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.830
|
Human |
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.830
|
Human Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.819
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.818
|
Human |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.817
|
Human |
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
1 |
0.802
|
|
|
|
nucleus localization
|
GO:0051647 |
20 |
0.801
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.798
|
Human |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.794
|
Human |
|
|
regulation of mitochondrial fission
|
GO:0090140 |
3 |
0.785
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.785
|
Fly |
|
|
spindle localization
|
GO:0051653 |
22 |
0.785
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.781
|
Human |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.780
|
Human |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.778
|
Human |
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
3 |
0.773
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.772
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.771
|
|
|
|
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051439 |
1 |
0.764
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.758
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.757
|
Human |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.752
|
Human |
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.747
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.738
|
Human |
|
|
membrane organization
|
GO:0061024 |
245 |
0.729
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.727
|
Human |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.720
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.719
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.705
|
Human |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.702
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.696
|
Fly |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.695
|
Human |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.693
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.693
|
Human |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.688
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.682
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.682
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.670
|
Human |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.669
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
3 |
0.669
|
|
|
|
cytokinesis
|
GO:0000910 |
17 |
0.659
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.655
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.642
|
|
|
|
regulation of epidermal cell division
|
GO:0010482 |
3 |
0.641
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.641
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.628
|
Human Fly |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.614
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.603
|
Human |
|
|
regulation of ligase activity
|
GO:0051340 |
10 |
0.602
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.591
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.559
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.557
|
Human |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.549
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.548
|
Human |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
2 |
0.544
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.543
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.540
|
Human |
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.536
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.532
|
|
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
3 |
0.532
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.530
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.518
|
Human |
|
|
organism emergence from protective structure
|
GO:0071684 |
4 |
0.518
|
|
|
|
vacuole organization
|
GO:0007033 |
38 |
0.513
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.512
|
Human |
|
|
chromosome segregation
|
GO:0007059 |
48 |
0.510
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.500
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.495
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.491
|
|
|
|
protein export from nucleus
|
GO:0006611 |
20 |
0.490
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.485
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.485
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.483
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.479
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
12 |
0.477
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.475
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
19 |
0.471
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.469
|
Human |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.462
|
Human Fly |
|
|
cell division
|
GO:0051301 |
120 |
0.454
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.454
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.448
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.440
|
Human |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.430
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.417
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.413
|
Human |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
7 |
0.409
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.404
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.396
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.393
|
Human |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.390
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.390
|
|
|
|
aggresome assembly
|
GO:0070842 |
2 |
0.388
|
|
|
|
negative regulation of actin filament depolymerization
|
GO:0030835 |
9 |
0.386
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.386
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.377
|
Human |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.359
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
17 |
0.355
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.354
|
Human |
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.350
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.348
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.346
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.341
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
11 |
0.338
|
|
|
|
epidermal cell division
|
GO:0010481 |
3 |
0.321
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.318
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.317
|
Human Fly |
|
|
zygote asymmetric cell division
|
GO:0010070 |
2 |
0.316
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.316
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.315
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.314
|
Human Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.305
|
Human |
|
|
inclusion body assembly
|
GO:0070841 |
3 |
0.303
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.298
|
Human |
|
|
hatching
|
GO:0035188 |
4 |
0.296
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.293
|
|
|
|
negative regulation of keratinocyte proliferation
|
GO:0010839 |
7 |
0.288
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
9 |
0.287
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.283
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.282
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.277
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.276
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.276
|
Human |
|
|
telencephalon development
|
GO:0021537 |
186 |
0.275
|
Human |
|
|
neuron migration
|
GO:0001764 |
122 |
0.275
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.274
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.274
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.271
|
|
|
|
intracellular distribution of mitochondria
|
GO:0048312 |
1 |
0.268
|
Human Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.266
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.263
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.258
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.255
|
Human |
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.254
|
Human |
|
|
regulation of substrate adhesion dependent cell spreading
|
GO:1900024 |
12 |
0.253
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.249
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.247
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.236
|
Human |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.234
|
|
|
|
establishment of spindle orientation
|
GO:0051294 |
15 |
0.234
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.230
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.229
|
Human |
|
|
membrane fusion
|
GO:0061025 |
38 |
0.229
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.229
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.228
|
Human |
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.222
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.220
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.220
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.220
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.218
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.215
|
Human |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.213
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.211
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.209
|
Human |
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.207
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.207
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.206
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.206
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.198
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.195
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.192
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.191
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.190
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.189
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.186
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.184
|
Human |
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.183
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.181
|
|
|
|
microtubule based movement
|
GO:0007018 |
84 |
0.181
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.180
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.180
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.180
|
|
|
|
actin filament depolymerization
|
GO:0030042 |
15 |
0.179
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.177
|
|
|
|
positive regulation of lamellipodium organization
|
GO:1902745 |
3 |
0.175
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.174
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.170
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.169
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.168
|
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
5 |
0.166
|
|
|
|
positive regulation of mitochondrial fission
|
GO:0090141 |
2 |
0.165
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.163
|
|
|
|
chromosome movement towards spindle pole
|
GO:0051305 |
3 |
0.162
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.161
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.160
|
|
|
|
keratinization
|
GO:0031424 |
9 |
0.160
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.159
|
|
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
2 |
0.158
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.156
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.155
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.155
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.154
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.154
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.154
|
|
|
|
physiological muscle hypertrophy
|
GO:0003298 |
3 |
0.153
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.152
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.150
|
Human |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.149
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.148
|
|
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.148
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.147
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.146
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.145
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.145
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.143
|
Worm |
|
|
vesicle organization
|
GO:0016050 |
60 |
0.143
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.143
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.141
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.137
|
Human |
|
|
necroptotic process
|
GO:0070266 |
21 |
0.137
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.137
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.133
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.132
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.132
|
|
|
|
negative regulation of cell growth involved in cardiac muscle cell development
|
GO:0061052 |
2 |
0.132
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.131
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.131
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.131
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.131
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.131
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.130
|
Human |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.130
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.130
|
|
|
|
regulation of cell growth involved in cardiac muscle cell development
|
GO:0061050 |
3 |
0.129
|
|
|
|
filopodium assembly
|
GO:0046847 |
19 |
0.128
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.126
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.126
|
|
|
|
protein targeting to vacuole
|
GO:0006623 |
3 |
0.126
|
|
|
|
inositol phosphate mediated signaling
|
GO:0048016 |
13 |
0.125
|
|
|
|
multicellular organismal water homeostasis
|
GO:0050891 |
23 |
0.125
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.124
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.124
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.123
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.123
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.123
|
|
|
|
protein stabilization
|
GO:0050821 |
25 |
0.122
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
13 |
0.122
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
9 |
0.122
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.121
|
Human |
|
|
limbic system development
|
GO:0021761 |
72 |
0.121
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.121
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.119
|
|
|
|
physiological cardiac muscle hypertrophy
|
GO:0003301 |
3 |
0.119
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.119
|
|
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
6 |
0.118
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.118
|
Human |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.117
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.116
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.115
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.113
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.111
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
18 |
0.110
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.109
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.108
|
|
|
|
post embryonic hemopoiesis
|
GO:0035166 |
4 |
0.107
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.106
|
Human |
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
20 |
0.106
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.105
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.105
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
57 |
0.105
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.104
|
Fly |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.104
|
|
|
|
mitochondrion localization
|
GO:0051646 |
9 |
0.103
|
Human Fly |
|
|
mitotic cell cycle embryonic
|
GO:0045448 |
5 |
0.103
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
11 |
0.103
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.103
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.101
|
Human |
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.100
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.099
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
30 |
0.099
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.098
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.098
|
Human |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.098
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.097
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.097
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.097
|
|
|
|
nuclear dna replication
|
GO:0033260 |
3 |
0.096
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.096
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.095
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.095
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.094
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.094
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.094
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.094
|
|
|
|
regulation of keratinocyte proliferation
|
GO:0010837 |
15 |
0.094
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.093
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.093
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.093
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.092
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.091
|
|
|
|
establishment of skin barrier
|
GO:0061436 |
14 |
0.091
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.091
|
Human |
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.089
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.088
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.088
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.086
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.086
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
21 |
0.086
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.085
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.085
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.085
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.085
|
Human |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.085
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.085
|
Human |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.084
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.084
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.083
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.082
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.082
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.082
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
10 |
0.081
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.081
|
Human |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.081
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.080
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.079
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.079
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.079
|
|
|
|
regulation of actin filament depolymerization
|
GO:0030834 |
13 |
0.079
|
|
|
|
water homeostasis
|
GO:0030104 |
27 |
0.078
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.076
|
|
|
|
negative regulation of dendrite development
|
GO:2000171 |
9 |
0.076
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.076
|
|
|
|
regulation of epidermis development
|
GO:0045682 |
33 |
0.075
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.075
|
|
|
|
regulation of water loss via skin
|
GO:0033561 |
16 |
0.074
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.074
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.074
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.074
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.072
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.072
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.072
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.071
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.071
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.071
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.070
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.069
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.069
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.069
|
|
|
|
positive regulation of epidermal cell differentiation
|
GO:0045606 |
6 |
0.069
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.068
|
|
|
|
negative regulation of nuclear division
|
GO:0051784 |
19 |
0.068
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.067
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.067
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.067
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.067
|
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
15 |
0.066
|
Human |
|
|
epidermis development
|
GO:0008544 |
187 |
0.066
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.066
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.066
|
|
|
|
protein folding
|
GO:0006457 |
28 |
0.066
|
|
|
|
exit from mitosis
|
GO:0010458 |
3 |
0.065
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.065
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.065
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.064
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.064
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.063
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.063
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.062
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.062
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.062
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
5 |
0.062
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.062
|
Fly |
|
|
nuclear migration
|
GO:0007097 |
6 |
0.061
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.061
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.060
|
Human |
|
|
cell maturation
|
GO:0048469 |
127 |
0.060
|
Human |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.060
|
Worm |
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.060
|
|
|
|
nuclear export
|
GO:0051168 |
34 |
0.059
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.059
|
Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.059
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
19 |
0.059
|
|
|
|
establishment of mitochondrion localization
|
GO:0051654 |
4 |
0.058
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.058
|
Human Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.058
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.058
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.058
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.058
|
|
|
|
exocyst localization
|
GO:0051601 |
2 |
0.057
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.056
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.056
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.056
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.055
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.055
|
Human |
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.055
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.055
|
|
|
|
positive regulation of substrate adhesion dependent cell spreading
|
GO:1900026 |
8 |
0.055
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.055
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.054
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.054
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.054
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.054
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.054
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.054
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.054
|
Human Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.054
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.053
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.053
|
Human |
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.053
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.053
|
|
|
|
fibroblast migration
|
GO:0010761 |
21 |
0.052
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.052
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.052
|
|
|
|
genetic imprinting
|
GO:0071514 |
27 |
0.052
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.052
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.052
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
37 |
0.052
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.052
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.051
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.051
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
12 |
0.051
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.051
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.051
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.051
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.050
|
Human |
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.050
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.050
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.049
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
25 |
0.049
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.049
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.049
|
|
|
|
positive regulation of lamellipodium assembly
|
GO:0010592 |
2 |
0.049
|
|
|
|
asymmetric cell division
|
GO:0008356 |
8 |
0.048
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.048
|
Worm |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.048
|
|
|
|
calcineurin nfat signaling cascade
|
GO:0033173 |
8 |
0.048
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.048
|
|
|
|
regulation of lamellipodium organization
|
GO:1902743 |
5 |
0.048
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.047
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.047
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.047
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.047
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.047
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.047
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.047
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.047
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
3 |
0.046
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.046
|
Human Mouse |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.046
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
25 |
0.046
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.046
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.045
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.045
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.045
|
Human |
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.045
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.045
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.045
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.045
|
Human |
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
20 |
0.044
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.044
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.044
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.044
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.044
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.044
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.044
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.044
|
Human |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.043
|
|
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.043
|
|
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
4 |
0.043
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.043
|
|
|
|
negative regulation of nfat protein import into nucleus
|
GO:0051534 |
3 |
0.043
|
|
