Mus musculus

71 known processes

Nbr1

neighbor of Brca1 gene 1

(Aliases: mKIAA0049)

Nbr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.317
male gamete generation GO:0048232 285 0.215
spermatogenesis GO:0007283 284 0.155
protein modification by small protein conjugation or removal GO:0070647 207 0.137
response to endoplasmic reticulum stress GO:0034976 53 0.108
cellular amino acid metabolic process GO:0006520 103 0.105
anion transport GO:0006820 177 0.101
inorganic anion transmembrane transport GO:0098661 29 0.099
ion transmembrane transport GO:0034220 361 0.096
lipid modification GO:0030258 65 0.069
cellular lipid metabolic process GO:0044255 323 0.062
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.061
inorganic ion transmembrane transport GO:0098660 234 0.060
cation transmembrane transport GO:0098655 266 0.059
regulation of cellular response to stress GO:0080135 159 0.057
cellular homeostasis GO:0019725 240 0.055
action potential GO:0001508 78 0.055
endomembrane system organization GO:0010256 147 0.053
protein modification by small protein conjugation GO:0032446 187 0.051
membrane organization GO:0061024 245 0.051
protein ubiquitination GO:0016567 171 0.051
neuronal action potential GO:0019228 54 0.046
intrinsic apoptotic signaling pathway GO:0097193 132 0.046
lipid localization GO:0010876 126 0.046
regulation of ion transport GO:0043269 215 0.046
response to extracellular stimulus GO:0009991 127 0.046
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.045
multicellular organismal signaling GO:0035637 91 0.045
chloride transmembrane transport GO:1902476 24 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.044
apoptotic signaling pathway GO:0097190 306 0.044
cellular response to starvation GO:0009267 57 0.043
Human
protein oligomerization GO:0051259 67 0.043
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.043
monosaccharide metabolic process GO:0005996 106 0.042
cation transport GO:0006812 399 0.042
positive regulation of cellular catabolic process GO:0031331 148 0.041
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.041
regulation of glucose metabolic process GO:0010906 60 0.041
myelination GO:0042552 74 0.041
organic acid biosynthetic process GO:0016053 86 0.040
cellular response to organonitrogen compound GO:0071417 145 0.039
lipid homeostasis GO:0055088 63 0.038
chromatin modification GO:0016568 187 0.038
skeletal system development GO:0001501 356 0.037
transmembrane transport GO:0055085 412 0.037
cell type specific apoptotic process GO:0097285 268 0.037
regulation of membrane lipid distribution GO:0097035 16 0.037
response to peptide GO:1901652 136 0.036
amine metabolic process GO:0009308 45 0.035
cellular response to cytokine stimulus GO:0071345 189 0.035
autophagy GO:0006914 45 0.035
Human
cellular amine metabolic process GO:0044106 44 0.034
negative regulation of protein modification process GO:0031400 163 0.034
small molecule catabolic process GO:0044282 71 0.034
leukocyte migration GO:0050900 124 0.034
macroautophagy GO:0016236 21 0.034
Human
male sex differentiation GO:0046661 109 0.033
response to nutrient levels GO:0031667 109 0.033
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
phospholipid transport GO:0015914 21 0.032
ensheathment of neurons GO:0007272 76 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.031
monocarboxylic acid metabolic process GO:0032787 191 0.031
homeostasis of number of cells GO:0048872 210 0.030
response to organonitrogen compound GO:0010243 246 0.030
peptidyl amino acid modification GO:0018193 336 0.030
lipid transport GO:0006869 98 0.029
development of primary sexual characteristics GO:0045137 143 0.029
cytokine production GO:0001816 319 0.028
positive regulation of protein modification process GO:0031401 299 0.027
glycerophospholipid metabolic process GO:0006650 71 0.027
modification dependent macromolecule catabolic process GO:0043632 133 0.027
cellular response to external stimulus GO:0071496 88 0.026
Human
monosaccharide biosynthetic process GO:0046364 44 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
peptidyl lysine modification GO:0018205 77 0.026
organic anion transport GO:0015711 137 0.025
ossification GO:0001503 216 0.025
cellular response to lipid GO:0071396 145 0.025
response to starvation GO:0042594 65 0.025
Human
myeloid leukocyte differentiation GO:0002573 119 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.025
myeloid cell differentiation GO:0030099 233 0.025
multicellular organismal homeostasis GO:0048871 164 0.025
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902235 11 0.025
regulation of carbohydrate biosynthetic process GO:0043255 40 0.024
oxidation reduction process GO:0055114 342 0.024
biomineral tissue development GO:0031214 64 0.024
regulation of protein transport GO:0051223 163 0.024
spermatid differentiation GO:0048515 115 0.024
regulation of membrane potential GO:0042391 192 0.023
b cell receptor signaling pathway GO:0050853 20 0.023
defense response to other organism GO:0098542 197 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
male anatomical structure morphogenesis GO:0090598 4 0.023
metal ion homeostasis GO:0055065 189 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
dna metabolic process GO:0006259 303 0.022
sequestering of metal ion GO:0051238 19 0.022
glucose metabolic process GO:0006006 92 0.022
positive regulation of macroautophagy GO:0016239 3 0.022
regulation of mapk cascade GO:0043408 248 0.022
cerebellar cortex development GO:0021695 48 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
response to growth factor GO:0070848 198 0.022
positive regulation of response to wounding GO:1903036 66 0.021
regulation of response to wounding GO:1903034 189 0.021
response to acid chemical GO:0001101 111 0.021
cytoplasmic transport GO:0016482 234 0.021
skeletal muscle organ development GO:0060538 163 0.021
protein localization to peroxisome GO:0072662 4 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
transmission of nerve impulse GO:0019226 76 0.021
anatomical structure homeostasis GO:0060249 145 0.020
cellular response to oxidative stress GO:0034599 76 0.020
regulation of homeostatic process GO:0032844 182 0.020
cellular response to peptide hormone stimulus GO:0071375 92 0.020
wound healing GO:0042060 157 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
response to peptide hormone GO:0043434 127 0.019
male genitalia morphogenesis GO:0048808 4 0.019
negative regulation of cell cycle GO:0045786 123 0.019
response to radiation GO:0009314 165 0.019
positive regulation of proteolysis GO:0045862 85 0.019
regulation of anatomical structure size GO:0090066 178 0.019
adipose tissue development GO:0060612 25 0.019
carbohydrate biosynthetic process GO:0016051 74 0.019
response to transforming growth factor beta GO:0071559 88 0.019
intracellular protein transport GO:0006886 204 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
carboxylic acid catabolic process GO:0046395 51 0.018
regulation of cell cycle GO:0051726 281 0.018
carbohydrate metabolic process GO:0005975 230 0.018
regulation of protein localization GO:0032880 231 0.018
axon ensheathment GO:0008366 76 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
potassium ion transport GO:0006813 52 0.018
bone mineralization GO:0030282 54 0.017
cellular response to arsenic containing substance GO:0071243 4 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
glycoprotein metabolic process GO:0009100 116 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
adult behavior GO:0030534 135 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
negative regulation of immune system process GO:0002683 209 0.017
positive regulation of nucleotide catabolic process GO:0030813 88 0.017
plasma membrane organization GO:0007009 90 0.017
positive regulation of cell death GO:0010942 224 0.017
protein catabolic process GO:0030163 221 0.017
response to epidermal growth factor GO:0070849 4 0.017
fatty acid metabolic process GO:0006631 121 0.016
fat cell differentiation GO:0045444 160 0.016
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
divalent inorganic cation transport GO:0072511 178 0.016
macromolecule catabolic process GO:0009057 281 0.016
chloride transport GO:0006821 32 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
glycerolipid metabolic process GO:0046486 122 0.016
regulation of gluconeogenesis GO:0006111 30 0.016
hexose biosynthetic process GO:0019319 39 0.015
response to inorganic substance GO:0010035 96 0.015
peroxisome organization GO:0007031 7 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
regulation of transferase activity GO:0051338 263 0.015
male gonad development GO:0008584 88 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
regulation of engulfment of apoptotic cell GO:1901074 2 0.015
cell division GO:0051301 120 0.015
neuron apoptotic process GO:0051402 142 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
cellular response to acid chemical GO:0071229 68 0.015
positive regulation of ion transport GO:0043270 65 0.015
leukocyte chemotaxis GO:0030595 69 0.014
gonad development GO:0008406 141 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
protein targeting GO:0006605 143 0.014
regulation of cell size GO:0008361 72 0.014
positive regulation of homeostatic process GO:0032846 64 0.014
sensory perception GO:0007600 245 0.014
developmental maturation GO:0021700 193 0.014
phospholipid metabolic process GO:0006644 87 0.014
maintenance of location GO:0051235 89 0.014
regulation of myeloid leukocyte differentiation GO:0002761 58 0.014
carboxylic acid transport GO:0046942 100 0.014
regulation of chromatin organization GO:1902275 57 0.014
phosphatidylethanolamine metabolic process GO:0046337 2 0.013
phagocytosis GO:0006909 66 0.013
protein polyubiquitination GO:0000209 33 0.013
osteoclast differentiation GO:0030316 62 0.013
schwann cell development GO:0014044 22 0.013
cell growth GO:0016049 130 0.013
regulation of cellular component size GO:0032535 121 0.013
circadian rhythm GO:0007623 114 0.013
protein acylation GO:0043543 64 0.013
cell maturation GO:0048469 127 0.013
phospholipid scrambling GO:0017121 7 0.013
macromolecule glycosylation GO:0043413 55 0.013
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
rna processing GO:0006396 105 0.013
gene silencing GO:0016458 38 0.013
organic acid transport GO:0015849 101 0.013
extracellular structure organization GO:0043062 148 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
cellular response to cadmium ion GO:0071276 3 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
myeloid cell homeostasis GO:0002262 114 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
chromatin organization GO:0006325 206 0.012
response to insulin GO:0032868 100 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
hexose metabolic process GO:0019318 98 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
lysosome organization GO:0007040 21 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
dendritic cell chemotaxis GO:0002407 7 0.012
small molecule biosynthetic process GO:0044283 132 0.012
negative regulation of multi organism process GO:0043901 68 0.012
positive regulation of potassium ion transport GO:0043268 3 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
positive regulation of autophagy GO:0010508 9 0.012
alcohol metabolic process GO:0006066 116 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
leukocyte differentiation GO:0002521 342 0.012
regulation of defense response GO:0031347 233 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
muscle cell differentiation GO:0042692 261 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
positive regulation of gtpase activity GO:0043547 85 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
male meiosis i GO:0007141 16 0.012
cellularization GO:0007349 1 0.011
establishment of protein localization to peroxisome GO:0072663 4 0.011
regulation of cell cycle process GO:0010564 160 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
histone h4 k16 acetylation GO:0043984 3 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
hemostasis GO:0007599 78 0.011
dephosphorylation GO:0016311 129 0.011
cell chemotaxis GO:0060326 81 0.011
cellular chemical homeostasis GO:0055082 215 0.011
male meiosis GO:0007140 37 0.011
protein localization to organelle GO:0033365 185 0.011
positive regulation of phagocytosis engulfment GO:0060100 3 0.011
wnt signaling pathway GO:0016055 188 0.011
ossification involved in bone maturation GO:0043931 12 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
tissue homeostasis GO:0001894 115 0.011
rab protein signal transduction GO:0032482 1 0.011
methylation GO:0032259 134 0.011
negative regulation of osteoclast differentiation GO:0045671 12 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
copper ion homeostasis GO:0055070 9 0.011
regulation of body fluid levels GO:0050878 162 0.011
glial cell differentiation GO:0010001 131 0.011
metencephalon development GO:0022037 89 0.011
negative regulation of nervous system development GO:0051961 156 0.011
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
acute inflammatory response GO:0002526 41 0.011
regulation of wound healing GO:0061041 40 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
dendritic cell migration GO:0036336 12 0.011
immune effector process GO:0002252 321 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
tube formation GO:0035148 140 0.011
regulation of myotube differentiation GO:0010830 62 0.011
alpha amino acid metabolic process GO:1901605 59 0.010
positive regulation of cytokine production GO:0001819 174 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
sequestering of calcium ion GO:0051208 18 0.010
cellular amino acid catabolic process GO:0009063 25 0.010
positive regulation of secretion by cell GO:1903532 114 0.010
dna recombination GO:0006310 92 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
regulation of macroautophagy GO:0016241 12 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
cytoskeleton dependent intracellular transport GO:0030705 50 0.010
nitrogen compound transport GO:0071705 271 0.010
peptidyl threonine phosphorylation GO:0018107 31 0.010
protein secretion GO:0009306 111 0.010
cellular response to nutrient levels GO:0031669 64 0.010
Human
regulation of mitotic cell cycle GO:0007346 126 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
positive regulation of myeloid cell differentiation GO:0045639 43 0.010
telencephalon development GO:0021537 186 0.010
canonical wnt signaling pathway GO:0060070 130 0.010

Nbr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.178
musculoskeletal system disease DOID:17 0 0.178
connective tissue disease DOID:65 0 0.178
bone disease DOID:0080001 0 0.073
bone remodeling disease DOID:0080005 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
cancer DOID:162 0 0.028
organ system cancer DOID:0050686 0 0.021
immune system cancer DOID:0060083 0 0.018
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.015