Mus musculus

46 known processes

Sgpp1

sphingosine-1-phosphate phosphatase 1

(Aliases: SPP,SPP1,AI463453,Spph1)

Sgpp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecule catabolic process GO:0009057 281 0.126
protein catabolic process GO:0030163 221 0.096
glycoprotein metabolic process GO:0009100 116 0.086
glycoprotein biosynthetic process GO:0009101 89 0.076
response to topologically incorrect protein GO:0035966 25 0.074
cellular macromolecule catabolic process GO:0044265 206 0.074
organic cyclic compound catabolic process GO:1901361 295 0.066
carbohydrate derivative catabolic process GO:1901136 231 0.065
ubiquitin dependent protein catabolic process GO:0006511 129 0.059
alcohol metabolic process GO:0006066 116 0.058
steroid metabolic process GO:0008202 119 0.054
organophosphate ester transport GO:0015748 28 0.048
response to endoplasmic reticulum stress GO:0034976 53 0.047
carbohydrate metabolic process GO:0005975 230 0.046
glycerolipid metabolic process GO:0046486 122 0.045
leukocyte differentiation GO:0002521 342 0.045
organic hydroxy compound metabolic process GO:1901615 203 0.043
oxidation reduction process GO:0055114 342 0.042
regulation of protein localization GO:0032880 231 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.040
cellular ketone metabolic process GO:0042180 84 0.039
golgi to endosome transport GO:0006895 3 0.038
heterocycle catabolic process GO:0046700 280 0.038
regulation of leukocyte differentiation GO:1902105 159 0.037
metal ion homeostasis GO:0055065 189 0.036
lipid biosynthetic process GO:0008610 179 0.036
aromatic compound catabolic process GO:0019439 286 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
cellular homeostasis GO:0019725 240 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
organophosphate catabolic process GO:0046434 232 0.033
nucleoside catabolic process GO:0009164 206 0.032
regulation of t cell activation GO:0050863 170 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.031
modification dependent macromolecule catabolic process GO:0043632 133 0.031
regulation of cell activation GO:0050865 289 0.030
cation homeostasis GO:0055080 212 0.030
regulation of inflammatory response GO:0050727 147 0.029
endomembrane system organization GO:0010256 147 0.028
macromolecule glycosylation GO:0043413 55 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
glycosyl compound metabolic process GO:1901657 246 0.026
transition metal ion homeostasis GO:0055076 54 0.026
cellular metal ion homeostasis GO:0006875 151 0.026
chemotaxis GO:0006935 247 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
membrane organization GO:0061024 245 0.025
glycoprotein catabolic process GO:0006516 5 0.025
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.025
nucleotide metabolic process GO:0009117 332 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
guanosine containing compound catabolic process GO:1901069 144 0.024
cellular chemical homeostasis GO:0055082 215 0.024
sphingolipid metabolic process GO:0006665 45 0.024
t cell differentiation in thymus GO:0033077 77 0.024
cellular amino acid metabolic process GO:0006520 103 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
cellular lipid metabolic process GO:0044255 323 0.024
myeloid cell differentiation GO:0030099 233 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
regulation of lymphocyte differentiation GO:0045619 107 0.022
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.022
action potential GO:0001508 78 0.022
immune effector process GO:0002252 321 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
ribonucleoside metabolic process GO:0009119 245 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
cytokine production GO:0001816 319 0.021
peptidyl amino acid modification GO:0018193 336 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
regulation of lipid metabolic process GO:0019216 118 0.020
transmission of nerve impulse GO:0019226 76 0.020
cellular protein catabolic process GO:0044257 155 0.020
single organism cell adhesion GO:0098602 156 0.020
t cell activation GO:0042110 289 0.020
regulation of myeloid leukocyte differentiation GO:0002761 58 0.020
cellular ion homeostasis GO:0006873 165 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
transmembrane transport GO:0055085 412 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
anion transport GO:0006820 177 0.020
embryonic organ morphogenesis GO:0048562 276 0.020
activation of rac gtpase activity GO:0032863 2 0.019
apoptotic signaling pathway GO:0097190 306 0.019
chromatin organization GO:0006325 206 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
regulation of cell size GO:0008361 72 0.019
axonogenesis GO:0007409 274 0.019
plasma membrane organization GO:0007009 90 0.019
iron ion homeostasis GO:0055072 36 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of cell cycle process GO:0010564 160 0.019
purine containing compound metabolic process GO:0072521 311 0.018
nucleoside metabolic process GO:0009116 246 0.018
immunoglobulin production GO:0002377 73 0.018
protein localization to organelle GO:0033365 185 0.018
membrane lipid metabolic process GO:0006643 53 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of myeloid cell differentiation GO:0045637 96 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
single organismal cell cell adhesion GO:0016337 131 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
cell division GO:0051301 120 0.017
production of molecular mediator of immune response GO:0002440 103 0.017
limb morphogenesis GO:0035108 149 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
protein localization to membrane GO:0072657 108 0.017
sterol metabolic process GO:0016125 58 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
skeletal system development GO:0001501 356 0.017
nucleoside phosphate catabolic process GO:1901292 222 0.017
ossification GO:0001503 216 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
cell adhesion GO:0007155 329 0.017
regulation of protein kinase b signaling GO:0051896 56 0.017
t cell proliferation GO:0042098 120 0.017
regulation of response to wounding GO:1903034 189 0.017
homeostasis of number of cells GO:0048872 210 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
cell aging GO:0007569 35 0.017
cellular transition metal ion homeostasis GO:0046916 32 0.016
lipid modification GO:0030258 65 0.016
cell type specific apoptotic process GO:0097285 268 0.016
cell activation involved in immune response GO:0002263 126 0.016
cofactor transport GO:0051181 4 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
response to growth factor GO:0070848 198 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
neural precursor cell proliferation GO:0061351 121 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
lymphocyte differentiation GO:0030098 242 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
response to reactive oxygen species GO:0000302 56 0.016
cholesterol metabolic process GO:0008203 56 0.016
lipid transport GO:0006869 98 0.015
mrna metabolic process GO:0016071 84 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
regulation of ras gtpase activity GO:0032318 88 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
response to organonitrogen compound GO:0010243 246 0.015
adaptive immune response GO:0002250 155 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
bone development GO:0060348 120 0.015
cytokinetic process GO:0032506 2 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
fatty acid metabolic process GO:0006631 121 0.015
sulfur compound biosynthetic process GO:0044272 37 0.015
multi multicellular organism process GO:0044706 109 0.014
rho protein signal transduction GO:0007266 32 0.014
regulation of protein transport GO:0051223 163 0.014
regulation of organelle organization GO:0033043 289 0.014
establishment of protein localization to membrane GO:0090150 54 0.014
bone morphogenesis GO:0060349 78 0.014
regulation of cell cycle GO:0051726 281 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
intra golgi vesicle mediated transport GO:0006891 1 0.014
hormone secretion GO:0046879 128 0.014
male gamete generation GO:0048232 285 0.014
purine containing compound catabolic process GO:0072523 213 0.014
lymphocyte proliferation GO:0046651 164 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
positive regulation of gtp catabolic process GO:0033126 85 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
glycosaminoglycan metabolic process GO:0030203 34 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
er nucleus signaling pathway GO:0006984 27 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
proteoglycan metabolic process GO:0006029 38 0.014
response to organic cyclic compound GO:0014070 198 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
regulation of t cell proliferation GO:0042129 92 0.014
cation transport GO:0006812 399 0.014
protein localization to chromatin GO:0071168 3 0.014
regulation of hormone levels GO:0010817 211 0.014
protein modification by small protein removal GO:0070646 21 0.013
tissue homeostasis GO:0001894 115 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
tube formation GO:0035148 140 0.013
nucleotide catabolic process GO:0009166 217 0.013
leukocyte mediated immunity GO:0002443 174 0.013
embryonic appendage morphogenesis GO:0035113 126 0.013
glycosylation GO:0070085 62 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
calcium ion homeostasis GO:0055074 127 0.013
compound eye development GO:0048749 1 0.013
positive regulation of phospholipase activity GO:0010518 3 0.013
multicellular organism growth GO:0035264 161 0.013
intracellular protein transport GO:0006886 204 0.013
respiratory system development GO:0060541 190 0.013
cellular amine metabolic process GO:0044106 44 0.013
inflammatory response GO:0006954 244 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.013
mapk cascade GO:0000165 281 0.013
protein glycosylation GO:0006486 55 0.013
localization within membrane GO:0051668 4 0.012
neuronal action potential GO:0019228 54 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
regulation of neuron projection development GO:0010975 169 0.012
camera type eye development GO:0043010 266 0.012
positive regulation of nervous system development GO:0051962 221 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
respiratory tube development GO:0030323 167 0.012
organelle assembly GO:0070925 177 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of t cell differentiation GO:0045580 83 0.012
digestive system development GO:0055123 200 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
chromatin modification GO:0016568 187 0.012
positive regulation of protein transport GO:0051222 93 0.012
protein secretion GO:0009306 111 0.012
ceramide metabolic process GO:0006672 31 0.012
negative regulation of cell size GO:0045792 3 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of rho gtpase activity GO:0032319 58 0.012
embryonic limb morphogenesis GO:0030326 126 0.012
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.012
regulation of cytokine production GO:0001817 266 0.012
protein ubiquitination GO:0016567 171 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
organic anion transport GO:0015711 137 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
response to radiation GO:0009314 165 0.012
response to light stimulus GO:0009416 135 0.012
appendage development GO:0048736 166 0.011
organelle localization GO:0051640 179 0.011
dephosphorylation GO:0016311 129 0.011
establishment of protein localization to vacuole GO:0072666 4 0.011
maintenance of location GO:0051235 89 0.011
regulation of cell migration GO:0030334 219 0.011
phosphorylated carbohydrate dephosphorylation GO:0046838 4 0.011
lung development GO:0030324 164 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
lipid homeostasis GO:0055088 63 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
mitotic cell cycle process GO:1903047 159 0.011
regulation of cellular component size GO:0032535 121 0.011
dna metabolic process GO:0006259 303 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
muscle tissue development GO:0060537 308 0.011
response to inorganic substance GO:0010035 96 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
regulation of intracellular transport GO:0032386 159 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
sensory organ morphogenesis GO:0090596 242 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
regulation of osteoblast differentiation GO:0045667 67 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
adult behavior GO:0030534 135 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
early endosome to late endosome transport GO:0045022 2 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
male sex differentiation GO:0046661 109 0.011
protein targeting GO:0006605 143 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
regulation of membrane potential GO:0042391 192 0.010
regulation of anatomical structure size GO:0090066 178 0.010
rac protein signal transduction GO:0016601 13 0.010
neurotransmitter transport GO:0006836 76 0.010
dna endoreduplication GO:0042023 4 0.010
positive regulation of apoptotic signaling pathway GO:2001235 95 0.010
proteoglycan biosynthetic process GO:0030166 20 0.010
protein localization to plasma membrane GO:0072659 57 0.010
forebrain development GO:0030900 302 0.010
cellular response to topologically incorrect protein GO:0035967 25 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
gtp metabolic process GO:0046039 144 0.010
sequestering of metal ion GO:0051238 19 0.010
lipid localization GO:0010876 126 0.010
regulation of ossification GO:0030278 112 0.010
gland development GO:0048732 330 0.010
cytoplasmic transport GO:0016482 234 0.010
negative regulation of cell cycle GO:0045786 123 0.010
negative regulation of immune system process GO:0002683 209 0.010
phospholipid metabolic process GO:0006644 87 0.010
regulation of dna methylation GO:0044030 12 0.010
regulation of myotube differentiation GO:0010830 62 0.010

Sgpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.124
inherited metabolic disorder DOID:655 0 0.088
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
retinal disease DOID:5679 0 0.031
retinal degeneration DOID:8466 0 0.031
sensory system disease DOID:0050155 0 0.031
eye and adnexa disease DOID:1492 0 0.031
eye disease DOID:5614 0 0.031
carbohydrate metabolic disorder DOID:2978 0 0.011
lysosomal storage disease DOID:3211 0 0.011