Mus musculus

46 known processes

Flna

filamin, alpha

(Aliases: ABP-280,Fln1,filamin-1,Dilp2,F730004A14Rik)

Flna biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.765
Human
axon guidance GO:0007411 141 0.691
Fly
actin cytoskeleton organization GO:0030036 220 0.602
cellular component assembly involved in morphogenesis GO:0010927 139 0.558
Human
regulation of cell adhesion GO:0030155 154 0.507
actin filament organization GO:0007015 113 0.491
Human Worm Fly
regulation of cell migration GO:0030334 219 0.446
wound healing GO:0042060 157 0.446
Human
nucleoside metabolic process GO:0009116 246 0.422
ras protein signal transduction GO:0007265 77 0.421
ribonucleoside metabolic process GO:0009119 245 0.403
ribonucleotide catabolic process GO:0009261 208 0.380
negative regulation of cellular component organization GO:0051129 194 0.374
striated muscle cell development GO:0055002 125 0.343
Mouse
regulation of endocytosis GO:0030100 69 0.329
purine nucleoside metabolic process GO:0042278 241 0.324
positive regulation of protein phosphorylation GO:0001934 242 0.320
nucleotide metabolic process GO:0009117 332 0.311
nucleobase containing small molecule metabolic process GO:0055086 352 0.308
microtubule cytoskeleton organization GO:0000226 157 0.308
Human
cellular response to growth factor stimulus GO:0071363 197 0.300
cell junction organization GO:0034330 77 0.297
actomyosin structure organization GO:0031032 56 0.287
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.284
mapk cascade GO:0000165 281 0.281
cell matrix adhesion GO:0007160 68 0.278
purine nucleoside triphosphate metabolic process GO:0009144 226 0.271
ribonucleotide metabolic process GO:0009259 291 0.269
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.267
muscle cell development GO:0055001 133 0.266
Mouse
positive regulation of mapk cascade GO:0043410 170 0.265
glycosyl compound catabolic process GO:1901658 206 0.263
regulation of cell motility GO:2000145 236 0.258
response to growth factor GO:0070848 198 0.242
organonitrogen compound catabolic process GO:1901565 264 0.241
regulation of organelle organization GO:0033043 289 0.235
Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.232
regulation of protein serine threonine kinase activity GO:0071900 157 0.230
purine containing compound metabolic process GO:0072521 311 0.226
nucleoside triphosphate catabolic process GO:0009143 205 0.224
muscle fiber development GO:0048747 76 0.222
Mouse
axonogenesis GO:0007409 274 0.221
Fly
purine ribonucleoside metabolic process GO:0046128 241 0.219
blood vessel morphogenesis GO:0048514 285 0.217
ribose phosphate metabolic process GO:0019693 291 0.216
muscle cell differentiation GO:0042692 261 0.209
Mouse
aromatic compound catabolic process GO:0019439 286 0.209
positive regulation of kinase activity GO:0033674 155 0.189
membrane organization GO:0061024 245 0.185
Human
small gtpase mediated signal transduction GO:0007264 97 0.184
chemotaxis GO:0006935 247 0.178
Fly
purine ribonucleotide metabolic process GO:0009150 290 0.172
gastrulation GO:0007369 116 0.171
organic cyclic compound catabolic process GO:1901361 295 0.169
negative regulation of phagocytosis GO:0050765 4 0.166
macromolecule catabolic process GO:0009057 281 0.166
Human
digestive tract development GO:0048565 190 0.164
muscle tissue development GO:0060537 308 0.164
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.163
cytoplasmic transport GO:0016482 234 0.162
purine nucleotide metabolic process GO:0006163 302 0.161
body morphogenesis GO:0010171 45 0.159
Worm
positive regulation of protein modification process GO:0031401 299 0.158
cell substrate adhesion GO:0031589 130 0.154
endocytosis GO:0006897 168 0.154
ameboidal type cell migration GO:0001667 128 0.151
regulation of vesicle mediated transport GO:0060627 139 0.150
nucleotide catabolic process GO:0009166 217 0.149
stem cell differentiation GO:0048863 268 0.149
response to transforming growth factor beta GO:0071559 88 0.149
cell junction assembly GO:0034329 52 0.142
regulation of mapk cascade GO:0043408 248 0.142
skeletal muscle organ development GO:0060538 163 0.140
Mouse
extracellular matrix organization GO:0030198 147 0.138
regulation of cellular amino acid metabolic process GO:0006521 5 0.135
lung development GO:0030324 164 0.131
epithelial cell development GO:0002064 159 0.129
Mouse Fly
nucleoside phosphate catabolic process GO:1901292 222 0.129
oxidation reduction process GO:0055114 342 0.121
myofibril assembly GO:0030239 34 0.121
protein localization to membrane GO:0072657 108 0.119
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.118
cardiac muscle tissue development GO:0048738 130 0.117
extracellular structure organization GO:0043062 148 0.117
Fly
stem cell development GO:0048864 219 0.115
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.115
cellular nitrogen compound catabolic process GO:0044270 280 0.114
epiboly GO:0090504 8 0.112
transmembrane transport GO:0055085 412 0.111
cellular amine metabolic process GO:0044106 44 0.111
ribonucleoside triphosphate metabolic process GO:0009199 220 0.110
purine containing compound catabolic process GO:0072523 213 0.108
collagen fibril organization GO:0030199 32 0.105
synaptic transmission GO:0007268 329 0.103
neuron death GO:0070997 154 0.101
response to organonitrogen compound GO:0010243 246 0.100
carbohydrate derivative catabolic process GO:1901136 231 0.099
heterocycle catabolic process GO:0046700 280 0.098
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.098
negative regulation of cellular protein metabolic process GO:0032269 247 0.096
cardiocyte differentiation GO:0035051 87 0.096
glycosyl compound metabolic process GO:1901657 246 0.096
lamellipodium morphogenesis GO:0072673 5 0.093
regulation of cellular catabolic process GO:0031329 242 0.092
regulation of purine nucleotide metabolic process GO:1900542 169 0.091
purine nucleotide catabolic process GO:0006195 211 0.091
myosin filament assembly GO:0031034 2 0.091
purine nucleoside triphosphate catabolic process GO:0009146 203 0.089
nuclear division GO:0000280 158 0.088
Human Worm Fly
cell cell junction organization GO:0045216 72 0.087
positive regulation of map kinase activity GO:0043406 84 0.087
regulation of protein kinase activity GO:0045859 232 0.087
peptidyl amino acid modification GO:0018193 336 0.086
protein catabolic process GO:0030163 221 0.084
Human
organophosphate catabolic process GO:0046434 232 0.084
wound healing spreading of cells GO:0044319 8 0.082
calcium ion transport GO:0006816 159 0.081
regulation of anatomical structure size GO:0090066 178 0.081
positive regulation of transferase activity GO:0051347 167 0.081
cellular amino acid metabolic process GO:0006520 103 0.080
oocyte axis specification GO:0007309 2 0.080
atp metabolic process GO:0046034 75 0.080
regulation of kinase activity GO:0043549 249 0.079
positive regulation of nervous system development GO:0051962 221 0.078
response to inorganic substance GO:0010035 96 0.078
lamellipodium organization GO:0097581 29 0.076
regulation of body fluid levels GO:0050878 162 0.076
Human
regulation of intracellular transport GO:0032386 159 0.076
Human
hemostasis GO:0007599 78 0.075
Human
sarcomere organization GO:0045214 24 0.075
mesenchyme development GO:0060485 152 0.074
regulation of map kinase activity GO:0043405 120 0.074
integrin mediated signaling pathway GO:0007229 27 0.073
regulation of membrane potential GO:0042391 192 0.072
plasma membrane organization GO:0007009 90 0.072
regulation of neuron differentiation GO:0045664 281 0.071
regulation of response to wounding GO:1903034 189 0.069
purine nucleoside catabolic process GO:0006152 205 0.068
cation transport GO:0006812 399 0.068
purine ribonucleoside catabolic process GO:0046130 205 0.068
nucleoside triphosphate metabolic process GO:0009141 230 0.068
cellular lipid metabolic process GO:0044255 323 0.067
ossification GO:0001503 216 0.067
endomembrane system organization GO:0010256 147 0.067
peptidyl serine modification GO:0018209 83 0.066
respiratory tube development GO:0030323 167 0.065
response to superoxide GO:0000303 16 0.065
cardiac myofibril assembly GO:0055003 12 0.065
regulation of nucleoside metabolic process GO:0009118 130 0.064
regulation of cell projection organization GO:0031344 206 0.063
muscle system process GO:0003012 141 0.063
cation transmembrane transport GO:0098655 266 0.063
purine ribonucleotide catabolic process GO:0009154 208 0.063
focal adhesion assembly GO:0048041 19 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
regulation of ion transport GO:0043269 215 0.060
regulation of purine nucleotide catabolic process GO:0033121 122 0.060
female gamete generation GO:0007292 74 0.060
Worm Fly
wnt signaling pathway GO:0016055 188 0.060
positive regulation of neuron projection development GO:0010976 79 0.059
regulation of nucleotide metabolic process GO:0006140 169 0.059
neuron projection guidance GO:0097485 141 0.059
Fly
positive regulation of protein kinase activity GO:0045860 144 0.058
protein localization to organelle GO:0033365 185 0.058
Human
monocarboxylic acid metabolic process GO:0032787 191 0.057
regulation of phagocytosis GO:0050764 33 0.057
ribonucleoside catabolic process GO:0042454 206 0.057
response to oxidative stress GO:0006979 123 0.057
regulation of canonical wnt signaling pathway GO:0060828 82 0.056
organelle fission GO:0048285 170 0.056
Human Worm Fly
regulation of system process GO:0044057 200 0.056
cell substrate junction assembly GO:0007044 24 0.056
regulation of cell adhesion mediated by integrin GO:0033628 13 0.056
respiratory system development GO:0060541 190 0.056
regulation of ossification GO:0030278 112 0.056
neuron migration GO:0001764 122 0.055
divalent inorganic cation homeostasis GO:0072507 138 0.052
glycerolipid biosynthetic process GO:0045017 50 0.052
cell adhesion mediated by integrin GO:0033627 18 0.051
nucleoside monophosphate metabolic process GO:0009123 85 0.051
negative regulation of protein metabolic process GO:0051248 282 0.051
Human
development of primary sexual characteristics GO:0045137 143 0.051
muscle contraction GO:0006936 101 0.050
cellular ketone metabolic process GO:0042180 84 0.050
cellular response to hormone stimulus GO:0032870 150 0.050
negative regulation of hydrolase activity GO:0051346 71 0.050
regulation of gtp catabolic process GO:0033124 113 0.049
regulation of neuron projection development GO:0010975 169 0.049
cellular chemical homeostasis GO:0055082 215 0.049
actin filament bundle assembly GO:0051017 40 0.049
adult behavior GO:0030534 135 0.048
Fly
homotypic cell cell adhesion GO:0034109 28 0.048
Human
kidney development GO:0001822 213 0.048
morphogenesis of an endothelium GO:0003159 2 0.048
cellular divalent inorganic cation homeostasis GO:0072503 127 0.048
multi multicellular organism process GO:0044706 109 0.047
myotube differentiation GO:0014902 105 0.047
blood vessel endothelial cell migration GO:0043534 23 0.047
regulation of cellular component biogenesis GO:0044087 181 0.047
positive regulation of growth GO:0045927 104 0.047
actin mediated cell contraction GO:0070252 15 0.046
cellular metal ion homeostasis GO:0006875 151 0.046
negative regulation of organelle organization GO:0010639 90 0.046
organelle assembly GO:0070925 177 0.046
Human
establishment of vesicle localization GO:0051650 81 0.046
ribonucleoside monophosphate metabolic process GO:0009161 80 0.046
myosin filament organization GO:0031033 3 0.046
organonitrogen compound biosynthetic process GO:1901566 192 0.046
positive regulation of glial cell proliferation GO:0060252 4 0.045
regulation of homeostatic process GO:0032844 182 0.045
mitotic cytokinesis GO:0000281 4 0.045
regulation of hydrolase activity GO:0051336 246 0.044
peripheral nervous system axon regeneration GO:0014012 2 0.044
nucleoside catabolic process GO:0009164 206 0.044
organophosphate biosynthetic process GO:0090407 122 0.044
regionalization GO:0003002 337 0.044
morphogenesis of an epithelial sheet GO:0002011 27 0.044
maintenance of location GO:0051235 89 0.043
Human
regulation of protein binding GO:0043393 60 0.043
neural precursor cell proliferation GO:0061351 121 0.043
gtp catabolic process GO:0006184 143 0.042
bone resorption GO:0045453 38 0.042
regulation of cell projection assembly GO:0060491 38 0.042
microtubule based process GO:0007017 236 0.041
Human
digestive system development GO:0055123 200 0.041
cell substrate adherens junction assembly GO:0007045 19 0.041
atp catabolic process GO:0006200 55 0.041
regulation of cytoskeleton organization GO:0051493 122 0.041
Fly
blood circulation GO:0008015 195 0.041
epithelial cell migration GO:0010631 63 0.040
negative regulation of cytoskeleton organization GO:0051494 36 0.040
fat cell differentiation GO:0045444 160 0.040
sequestering of calcium ion GO:0051208 18 0.039
striated muscle tissue development GO:0014706 293 0.039
Mouse
regulation of tube size GO:0035150 57 0.039
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.039
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 9 0.038
activation of immune response GO:0002253 138 0.038
cellular homeostasis GO:0019725 240 0.038
response to extracellular stimulus GO:0009991 127 0.038
calcium ion homeostasis GO:0055074 127 0.037
multicellular organismal homeostasis GO:0048871 164 0.037
guanosine containing compound metabolic process GO:1901068 144 0.037
regulation of actin filament based process GO:0032970 99 0.037
neuron apoptotic process GO:0051402 142 0.037
oocyte construction GO:0007308 2 0.037
negative regulation of wnt signaling pathway GO:0030178 73 0.037
negative regulation of cell proliferation GO:0008285 296 0.037
glycerophospholipid biosynthetic process GO:0046474 32 0.036
peptidyl serine phosphorylation GO:0018105 74 0.036
vasodilation GO:0042311 28 0.036
rho protein signal transduction GO:0007266 32 0.036
camera type eye development GO:0043010 266 0.036
renal system development GO:0072001 225 0.035
cation homeostasis GO:0055080 212 0.035
response to oxygen radical GO:0000305 16 0.035
small molecule biosynthetic process GO:0044283 132 0.035
protein processing GO:0016485 163 0.035
regulation of transferase activity GO:0051338 263 0.034
purine nucleoside monophosphate catabolic process GO:0009128 58 0.034
regulation of cellular response to stress GO:0080135 159 0.033
integrin activation GO:0033622 8 0.033
regulation of actin cytoskeleton organization GO:0032956 84 0.033
actin filament depolymerization GO:0030042 15 0.033
negative regulation of neuron apoptotic process GO:0043524 92 0.033
single organism cell adhesion GO:0098602 156 0.033
Human
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
mesodermal cell migration GO:0008078 4 0.033
regulation of wnt signaling pathway GO:0030111 123 0.033
substrate dependent cell migration cell extension GO:0006930 4 0.032
purine nucleoside monophosphate metabolic process GO:0009126 81 0.032
regulation of lamellipodium assembly GO:0010591 3 0.032
positive regulation of cell projection organization GO:0031346 95 0.032
single organismal cell cell adhesion GO:0016337 131 0.032
Human
phospholipid metabolic process GO:0006644 87 0.032
negative regulation of molecular function GO:0044092 258 0.032
Human
meiotic cell cycle GO:0051321 122 0.032
Worm
cytosolic calcium ion homeostasis GO:0051480 70 0.032
response to acid chemical GO:0001101 111 0.032
gland development GO:0048732 330 0.032
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
canonical wnt signaling pathway GO:0060070 130 0.032
actin filament based movement GO:0030048 23 0.031
mitochondrion organization GO:0007005 134 0.031
substrate adhesion dependent cell spreading GO:0034446 30 0.031
cell type specific apoptotic process GO:0097285 268 0.031
negative regulation of actin filament depolymerization GO:0030835 9 0.031
negative regulation of cell migration GO:0030336 59 0.031
receptor mediated endocytosis GO:0006898 51 0.030
cellular response to oxidative stress GO:0034599 76 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.030
regulation of neuron death GO:1901214 134 0.030
negative regulation of ras protein signal transduction GO:0046580 18 0.030
ion transmembrane transport GO:0034220 361 0.030
gtp metabolic process GO:0046039 144 0.030
mitotic cell cycle GO:0000278 195 0.030
Human Fly
t cell activation GO:0042110 289 0.030
negative regulation of phosphorylation GO:0042326 166 0.029
regulation of tissue remodeling GO:0034103 38 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
fertilization GO:0009566 127 0.029
mitotic cell cycle process GO:1903047 159 0.029
Human Fly
positive regulation of gtp catabolic process GO:0033126 85 0.029
cell division GO:0051301 120 0.029
phospholipid biosynthetic process GO:0008654 36 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
positive regulation of neuron differentiation GO:0045666 141 0.029
negative regulation of stress fiber assembly GO:0051497 4 0.028
maintenance of protein location in nucleus GO:0051457 2 0.028
positive regulation of cell development GO:0010720 237 0.028
intracellular mrna localization GO:0008298 4 0.028
tissue migration GO:0090130 68 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.028
wound healing spreading of epidermal cells GO:0035313 5 0.027
regulation of blood vessel size GO:0050880 56 0.027
mesenchymal cell development GO:0014031 93 0.027
regulation of protein transport GO:0051223 163 0.027
Human
response to metal ion GO:0010038 47 0.027
second messenger mediated signaling GO:0019932 73 0.027
regulation of cell cycle process GO:0010564 160 0.027
circulatory system process GO:0003013 197 0.027
gonad development GO:0008406 141 0.027
regulation of neurotransmitter levels GO:0001505 87 0.026
defecation GO:0030421 1 0.026
cellular ion homeostasis GO:0006873 165 0.026
organic acid biosynthetic process GO:0016053 86 0.026
response to organic cyclic compound GO:0014070 198 0.026
regulation of blood pressure GO:0008217 93 0.026
organelle localization GO:0051640 179 0.026
pole plasm assembly GO:0007315 2 0.026
regulation of bone resorption GO:0045124 24 0.026
nucleoside monophosphate catabolic process GO:0009125 59 0.026
regulation of osteoblast differentiation GO:0045667 67 0.026
striated muscle myosin thick filament assembly GO:0071688 1 0.026
regulation of protein depolymerization GO:1901879 26 0.026
heart process GO:0003015 94 0.026
multicellular organismal signaling GO:0035637 91 0.026
response to reactive oxygen species GO:0000302 56 0.025
eating behavior GO:0042755 15 0.025
neurotransmitter transport GO:0006836 76 0.025
protein maturation GO:0051604 176 0.025
ribonucleoside monophosphate catabolic process GO:0009158 57 0.025
negative regulation of proteolysis GO:0045861 74 0.025
compound eye development GO:0048749 1 0.025
angiogenesis GO:0001525 201 0.025
glycerolipid metabolic process GO:0046486 122 0.025
cardiac muscle cell differentiation GO:0055007 69 0.025
stress activated protein kinase signaling cascade GO:0031098 81 0.025
carboxylic acid biosynthetic process GO:0046394 86 0.024
positive regulation of cell death GO:0010942 224 0.024
substrate dependent cell migration GO:0006929 18 0.024
activation of mapk activity involved in innate immune response GO:0035419 2 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
protein localization to nucleus GO:0034504 121 0.024
Human
negative regulation of transferase activity GO:0051348 85 0.024
meiotic cell cycle process GO:1903046 77 0.024
glial cell development GO:0021782 54 0.024
regulation of cell shape GO:0008360 39 0.024
gene silencing by mirna GO:0035195 10 0.023
syncytium formation by plasma membrane fusion GO:0000768 42 0.023
epithelial to mesenchymal transition GO:0001837 47 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
regulation of establishment of protein localization GO:0070201 181 0.023
Human
skeletal muscle tissue regeneration GO:0043403 20 0.023
positive regulation of cell migration GO:0030335 109 0.023
digestive tract morphogenesis GO:0048546 147 0.023
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.023
oocyte anterior posterior axis specification GO:0007314 2 0.023
skeletal myofibril assembly GO:0014866 4 0.023
cell cell adhesion GO:0098609 41 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.023
blood coagulation GO:0007596 76 0.023
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.023
cytosolic calcium ion transport GO:0060401 48 0.023
negative regulation of nervous system development GO:0051961 156 0.022
regulation of hormone levels GO:0010817 211 0.022
early endosome to late endosome transport GO:0045022 2 0.022
response to radiation GO:0009314 165 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
salivary gland development GO:0007431 37 0.022
regulation of systemic arterial blood pressure GO:0003073 61 0.022
leukocyte cell cell adhesion GO:0007159 14 0.022
negative regulation of apoptotic signaling pathway GO:2001234 104 0.022
negative regulation of neuron death GO:1901215 98 0.022
cardiac muscle contraction GO:0060048 32 0.022
anatomical structure homeostasis GO:0060249 145 0.022
cellular calcium ion homeostasis GO:0006874 119 0.022
negative regulation of cellular amine metabolic process GO:0033239 1 0.022
single fertilization GO:0007338 82 0.022
regulation of blood circulation GO:1903522 93 0.022
g1 s transition of mitotic cell cycle GO:0000082 57 0.021
glycerophospholipid metabolic process GO:0006650 71 0.021
negative regulation of protein phosphorylation GO:0001933 126 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
positive regulation of homeostatic process GO:0032846 64 0.021
erk1 and erk2 cascade GO:0070371 77 0.021
filopodium assembly GO:0046847 19 0.021
glial cell differentiation GO:0010001 131 0.021
signal transduction in absence of ligand GO:0038034 55 0.021
response to peptide hormone GO:0043434 127 0.021
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.021
superoxide metabolic process GO:0006801 27 0.021
negative regulation of protein modification process GO:0031400 163 0.021
regulation of angiogenesis GO:0045765 81 0.021
embryonic skeletal system development GO:0048706 120 0.021
adult locomotory behavior GO:0008344 91 0.021
negative regulation of peptidase activity GO:0010466 46 0.021
osteoblast development GO:0002076 17 0.021
learning GO:0007612 98 0.021
Fly
regulation of actin polymerization or depolymerization GO:0008064 45 0.020
positive regulation of necrotic cell death GO:0010940 1 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
macromolecular complex disassembly GO:0032984 43 0.020
divalent inorganic cation transport GO:0072511 178 0.020
negative regulation of homeostatic process GO:0032845 71 0.020
response to oxygen levels GO:0070482 62 0.020
hydrogen transport GO:0006818 35 0.020
striated muscle contraction GO:0006941 45 0.020
regulation of cellular component size GO:0032535 121 0.020
engulfment of apoptotic cell GO:0043652 3 0.020
response to testosterone GO:0033574 3 0.020
apoptotic signaling pathway GO:0097190 306 0.020
protein localization to plasma membrane GO:0072659 57 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
Human
cell aging GO:0007569 35 0.020
nuclear transport GO:0051169 139 0.020
Human
embryonic organ morphogenesis GO:0048562 276 0.020
heart morphogenesis GO:0003007 178 0.019
cytokinesis GO:0000910 17 0.019
coagulation GO:0050817 78 0.019
Human
regulation of cell activation GO:0050865 289 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.019
regulation of t cell activation GO:0050863 170 0.019
divalent metal ion transport GO:0070838 172 0.019
regulation of protein complex disassembly GO:0043244 28 0.019
regulation of schwann cell proliferation GO:0010624 2 0.019
cytokinetic process GO:0032506 2 0.019
cellularization GO:0007349 1 0.019
cellular response to salt stress GO:0071472 1 0.019
positive regulation of cell growth GO:0030307 33 0.019
microtubule polymerization or depolymerization GO:0031109 26 0.019
negative regulation of protein maturation GO:1903318 79 0.019
cell growth GO:0016049 130 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
calcium ion transport into cytosol GO:0060402 48 0.019
forebrain development GO:0030900 302 0.019
stress activated mapk cascade GO:0051403 80 0.019
germ cell development GO:0007281 185 0.019
Fly
chronological cell aging GO:0001300 1 0.019
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.019
regulation of wound healing GO:0061041 40 0.019
cellular protein complex disassembly GO:0043624 36 0.018
myeloid cell differentiation GO:0030099 233 0.018
leukocyte migration GO:0050900 124 0.018
regulation of cell cycle GO:0051726 281 0.018
gliogenesis GO:0042063 141 0.018
sensory organ morphogenesis GO:0090596 242 0.018
maternal determination of anterior posterior axis embryo GO:0008358 2 0.018
leukocyte differentiation GO:0002521 342 0.018
negative regulation of endocytosis GO:0045806 12 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
molting cycle GO:0042303 90 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
skin development GO:0043588 220 0.018
Mouse
liver development GO:0001889 66 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
multicellular organism growth GO:0035264 161 0.018
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.018
phagocytosis GO:0006909 66 0.018
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.018
adherens junction assembly GO:0034333 22 0.018
prevention of polyspermy GO:0060468 4 0.017
regulation of skeletal muscle fiber development GO:0048742 36 0.017
epiboly involved in wound healing GO:0090505 8 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
regulation of bone remodeling GO:0046850 28 0.017
positive regulation of protein transport GO:0051222 93 0.017
Human
nitrogen compound transport GO:0071705 271 0.017
activation of mapk activity GO:0000187 59 0.017
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.017
bone development GO:0060348 120 0.017
defense response to other organism GO:0098542 197 0.017
immune effector process GO:0002252 321 0.017
dna metabolic process GO:0006259 303 0.017
neuron projection extension GO:1990138 64 0.017

Flna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.142
nervous system disease DOID:863 0 0.142
musculoskeletal system disease DOID:17 0 0.101
sensory system disease DOID:0050155 0 0.076
eye and adnexa disease DOID:1492 0 0.048
connective tissue disease DOID:65 0 0.027
retinal disease DOID:5679 0 0.022
retinal degeneration DOID:8466 0 0.022
eye disease DOID:5614 0 0.022