Mus musculus

5 known processes

Hadhb

hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit

(Aliases: 4930479F15Rik,Mtpb)

Hadhb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
thioester metabolic process GO:0035383 19 0.661
fatty acid oxidation GO:0019395 28 0.465
Rat
monocarboxylic acid metabolic process GO:0032787 191 0.366
Rat
cellular ketone metabolic process GO:0042180 84 0.347
fatty acid metabolic process GO:0006631 121 0.286
Rat
acyl coa metabolic process GO:0006637 19 0.245
small molecule biosynthetic process GO:0044283 132 0.215
cellular lipid metabolic process GO:0044255 323 0.212
Rat
coenzyme biosynthetic process GO:0009108 23 0.188
coenzyme metabolic process GO:0006732 52 0.172
oxidation reduction process GO:0055114 342 0.139
fatty acid beta oxidation GO:0006635 16 0.134
Rat
very long chain fatty acid metabolic process GO:0000038 8 0.111
organic hydroxy compound metabolic process GO:1901615 203 0.104
nucleoside triphosphate metabolic process GO:0009141 230 0.097
nucleobase containing small molecule metabolic process GO:0055086 352 0.094
cofactor metabolic process GO:0051186 80 0.093
small molecule catabolic process GO:0044282 71 0.085
Rat
acetyl coa biosynthetic process GO:0006085 5 0.080
lipid modification GO:0030258 65 0.079
Rat
carnitine metabolic process GO:0009437 7 0.076
nucleotide metabolic process GO:0009117 332 0.076
anion transport GO:0006820 177 0.074
cellular amine metabolic process GO:0044106 44 0.072
mitochondrial transport GO:0006839 36 0.070
lipid biosynthetic process GO:0008610 179 0.066
purine ribonucleoside metabolic process GO:0046128 241 0.066
energy derivation by oxidation of organic compounds GO:0015980 77 0.066
lipid oxidation GO:0034440 29 0.061
Rat
nucleoside phosphate metabolic process GO:0006753 338 0.060
generation of precursor metabolites and energy GO:0006091 103 0.054
ribonucleotide metabolic process GO:0009259 291 0.051
regulation of cellular catabolic process GO:0031329 242 0.049
membrane organization GO:0061024 245 0.049
very long chain fatty acid catabolic process GO:0042760 2 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.048
sulfur compound metabolic process GO:0006790 100 0.048
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
monocarboxylic acid catabolic process GO:0072329 27 0.046
Rat
purine nucleotide metabolic process GO:0006163 302 0.044
regulation of lipid metabolic process GO:0019216 118 0.043
sulfur compound biosynthetic process GO:0044272 37 0.043
acyl coa biosynthetic process GO:0071616 7 0.043
lipid catabolic process GO:0016042 69 0.042
Rat
organic cyclic compound catabolic process GO:1901361 295 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.041
defense response to bacterium GO:0042742 119 0.040
regulation of hormone levels GO:0010817 211 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.039
protein localization to organelle GO:0033365 185 0.039
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.038
amine metabolic process GO:0009308 45 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
maintenance of location GO:0051235 89 0.035
organic hydroxy compound biosynthetic process GO:1901617 77 0.035
atp metabolic process GO:0046034 75 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.035
nitrogen compound transport GO:0071705 271 0.035
lipid localization GO:0010876 126 0.035
glycosyl compound metabolic process GO:1901657 246 0.034
acylglycerol metabolic process GO:0006639 55 0.034
carboxylic acid biosynthetic process GO:0046394 86 0.034
progesterone metabolic process GO:0042448 4 0.033
succinyl coa metabolic process GO:0006104 1 0.033
organic anion transport GO:0015711 137 0.033
nucleoside metabolic process GO:0009116 246 0.032
epithelial cell development GO:0002064 159 0.032
purine nucleoside metabolic process GO:0042278 241 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.028
regulation of intracellular transport GO:0032386 159 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
aromatic compound catabolic process GO:0019439 286 0.027
carbohydrate metabolic process GO:0005975 230 0.027
steroid metabolic process GO:0008202 119 0.027
mitochondrion organization GO:0007005 134 0.027
protein oligomerization GO:0051259 67 0.027
leukocyte differentiation GO:0002521 342 0.026
nucleotide catabolic process GO:0009166 217 0.026
apoptotic signaling pathway GO:0097190 306 0.026
protein localization to membrane GO:0072657 108 0.025
synaptic transmission GO:0007268 329 0.025
nucleoside monophosphate metabolic process GO:0009123 85 0.025
pyruvate transport GO:0006848 2 0.025
alcohol metabolic process GO:0006066 116 0.024
heterocycle catabolic process GO:0046700 280 0.024
amino acid betaine metabolic process GO:0006577 7 0.024
protein maturation GO:0051604 176 0.024
positive regulation of protein modification process GO:0031401 299 0.024
purine containing compound catabolic process GO:0072523 213 0.024
transmembrane transport GO:0055085 412 0.024
regulation of leukocyte differentiation GO:1902105 159 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
thioester biosynthetic process GO:0035384 7 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
purine nucleoside monophosphate metabolic process GO:0009126 81 0.024
cellular respiration GO:0045333 38 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
organic acid biosynthetic process GO:0016053 86 0.023
citrate metabolic process GO:0006101 3 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
carboxylic acid catabolic process GO:0046395 51 0.023
Rat
cellular lipid catabolic process GO:0044242 52 0.023
Rat
glucose metabolic process GO:0006006 92 0.022
organic acid catabolic process GO:0016054 51 0.022
Rat
cation transport GO:0006812 399 0.022
intracellular protein transport GO:0006886 204 0.022
cellular amino acid metabolic process GO:0006520 103 0.022
endocytosis GO:0006897 168 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
c21 steroid hormone biosynthetic process GO:0006700 3 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
muscle tissue development GO:0060537 308 0.021
purine containing compound metabolic process GO:0072521 311 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
progesterone biosynthetic process GO:0006701 1 0.021
acetyl coa metabolic process GO:0006084 8 0.021
male sex differentiation GO:0046661 109 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
hormone metabolic process GO:0042445 86 0.020
organophosphate catabolic process GO:0046434 232 0.020
defense response to other organism GO:0098542 197 0.019
hepaticobiliary system development GO:0061008 67 0.019
negative regulation of molecular function GO:0044092 258 0.019
renal system development GO:0072001 225 0.019
neural tube formation GO:0001841 108 0.019
action potential GO:0001508 78 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
response to organonitrogen compound GO:0010243 246 0.019
striated muscle tissue development GO:0014706 293 0.019
spermatogenesis GO:0007283 284 0.019
development of primary male sexual characteristics GO:0046546 88 0.019
microtubule based process GO:0007017 236 0.018
regulation of cell activation GO:0050865 289 0.018
lipid storage GO:0019915 36 0.018
protein processing GO:0016485 163 0.018
regulation of kinase activity GO:0043549 249 0.018
glycerolipid metabolic process GO:0046486 122 0.018
cell type specific apoptotic process GO:0097285 268 0.018
establishment of protein localization to organelle GO:0072594 118 0.017
positive regulation of cell death GO:0010942 224 0.017
macromolecule catabolic process GO:0009057 281 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
protein targeting GO:0006605 143 0.017
inflammatory response GO:0006954 244 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
gland development GO:0048732 330 0.017
development of primary sexual characteristics GO:0045137 143 0.017
nadh metabolic process GO:0006734 1 0.017
intracellular cholesterol transport GO:0032367 3 0.017
innate immune response GO:0045087 157 0.017
gonad development GO:0008406 141 0.017
ion transmembrane transport GO:0034220 361 0.017
response to organic cyclic compound GO:0014070 198 0.017
regulation of transferase activity GO:0051338 263 0.016
cellular response to lipid GO:0071396 145 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
fatty acid alpha oxidation GO:0001561 2 0.016
myeloid cell differentiation GO:0030099 233 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
tricarboxylic acid metabolic process GO:0072350 5 0.016
regulation of organelle organization GO:0033043 289 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
regulation of protein localization GO:0032880 231 0.016
regulation of membrane potential GO:0042391 192 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.015
phospholipid metabolic process GO:0006644 87 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
tissue homeostasis GO:0001894 115 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
multicellular organismal signaling GO:0035637 91 0.015
cytoplasmic transport GO:0016482 234 0.015
multicellular organism growth GO:0035264 161 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
endomembrane system organization GO:0010256 147 0.015
protein homooligomerization GO:0051260 43 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
positive regulation of growth GO:0045927 104 0.014
ossification GO:0001503 216 0.014
nuclear transport GO:0051169 139 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
organic hydroxy compound transport GO:0015850 93 0.014
positive regulation of kinase activity GO:0033674 155 0.014
transmission of nerve impulse GO:0019226 76 0.014
cellularization GO:0007349 1 0.014
male gamete generation GO:0048232 285 0.014
dna metabolic process GO:0006259 303 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
peptidyl amino acid modification GO:0018193 336 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of secretion GO:0051046 274 0.014
triglyceride metabolic process GO:0006641 51 0.014
regulation of secretion by cell GO:1903530 249 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
homeostasis of number of cells GO:0048872 210 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
hexose biosynthetic process GO:0019319 39 0.014
inositol trisphosphate metabolic process GO:0032957 5 0.014
carbohydrate biosynthetic process GO:0016051 74 0.014
mapk cascade GO:0000165 281 0.014
regulation of lipid transport GO:0032368 36 0.013
negative regulation of transferase activity GO:0051348 85 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
regulation of protein transport GO:0051223 163 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
liver development GO:0001889 66 0.013
dna catabolic process endonucleolytic GO:0000737 15 0.013
response to lipopolysaccharide GO:0032496 128 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
retinoid metabolic process GO:0001523 24 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
amide transport GO:0042886 138 0.013
nucleoside catabolic process GO:0009164 206 0.013
response to copper ion GO:0046688 3 0.013
regulation of steroid metabolic process GO:0019218 39 0.013
phagocytosis GO:0006909 66 0.013
regulation of mapk cascade GO:0043408 248 0.013
adult behavior GO:0030534 135 0.013
dephosphorylation GO:0016311 129 0.013
monosaccharide metabolic process GO:0005996 106 0.013
regulation of response to wounding GO:1903034 189 0.013
regulation of hydrolase activity GO:0051336 246 0.012
protein localization to nucleus GO:0034504 121 0.012
substantia nigra development GO:0021762 2 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
circulatory system process GO:0003013 197 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
cofactor biosynthetic process GO:0051188 41 0.012
fatty acyl coa metabolic process GO:0035337 4 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of map kinase activity GO:0043405 120 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
alcohol biosynthetic process GO:0046165 43 0.012
connective tissue development GO:0061448 179 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
apoptotic mitochondrial changes GO:0008637 48 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
cardiac muscle tissue development GO:0048738 130 0.012
glycosyl compound catabolic process GO:1901658 206 0.012
plasma membrane organization GO:0007009 90 0.012
hormone secretion GO:0046879 128 0.012
positive regulation of glycolytic process GO:0045821 4 0.011
regulation of glucose metabolic process GO:0010906 60 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
t cell activation GO:0042110 289 0.011
intracellular lipid transport GO:0032365 3 0.011
response to starvation GO:0042594 65 0.011
regulation of fatty acid beta oxidation GO:0031998 1 0.011
anatomical structure homeostasis GO:0060249 145 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
male gonad development GO:0008584 88 0.011
epithelial cell morphogenesis GO:0003382 41 0.011
cation transmembrane transport GO:0098655 266 0.011
monosaccharide biosynthetic process GO:0046364 44 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
hexose metabolic process GO:0019318 98 0.011
neural tube development GO:0021915 160 0.011
mitochondrial membrane organization GO:0007006 26 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
negative regulation of immune system process GO:0002683 209 0.011
regulation of homeostatic process GO:0032844 182 0.011
cellular ion homeostasis GO:0006873 165 0.011
tube closure GO:0060606 91 0.011
extracellular structure organization GO:0043062 148 0.011
protein catabolic process GO:0030163 221 0.011
regulation of protein kinase activity GO:0045859 232 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
neuronal action potential GO:0019228 54 0.011
phospholipid transport GO:0015914 21 0.011
multi multicellular organism process GO:0044706 109 0.010
stem cell development GO:0048864 219 0.010
protein tetramerization GO:0051262 23 0.010
skeletal system development GO:0001501 356 0.010
immune effector process GO:0002252 321 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of peptide transport GO:0090087 91 0.010

Hadhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.086
inherited metabolic disorder DOID:655 0 0.079
disease of cellular proliferation DOID:14566 0 0.032
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
hyperinsulinemic hypoglycemia DOID:13317 0 0.017
carbohydrate metabolic disorder DOID:2978 0 0.017
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.011