Mus musculus

31 known processes

Asl

argininosuccinate lyase

(Aliases: 2510006M18Rik)

Asl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.094
oxidation reduction process GO:0055114 342 0.077
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
carbohydrate metabolic process GO:0005975 230 0.058
alcohol metabolic process GO:0006066 116 0.054
organonitrogen compound biosynthetic process GO:1901566 192 0.050
organic hydroxy compound metabolic process GO:1901615 203 0.049
cation transport GO:0006812 399 0.049
cellular lipid metabolic process GO:0044255 323 0.047
regulation of cellular ketone metabolic process GO:0010565 66 0.047
amine metabolic process GO:0009308 45 0.040
sulfur compound metabolic process GO:0006790 100 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
transmembrane transport GO:0055085 412 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.038
cellular amine metabolic process GO:0044106 44 0.037
hexose metabolic process GO:0019318 98 0.037
monosaccharide metabolic process GO:0005996 106 0.036
nucleotide metabolic process GO:0009117 332 0.035
small molecule biosynthetic process GO:0044283 132 0.034
macromolecule catabolic process GO:0009057 281 0.034
monocarboxylic acid metabolic process GO:0032787 191 0.032
cellular macromolecule catabolic process GO:0044265 206 0.032
carboxylic acid biosynthetic process GO:0046394 86 0.031
membrane organization GO:0061024 245 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
cellular homeostasis GO:0019725 240 0.029
alpha amino acid metabolic process GO:1901605 59 0.029
regulation of apoptotic signaling pathway GO:2001233 197 0.029
regulation of ion transport GO:0043269 215 0.029
ion transmembrane transport GO:0034220 361 0.028
male gamete generation GO:0048232 285 0.027
protein catabolic process GO:0030163 221 0.027
cellular modified amino acid metabolic process GO:0006575 63 0.026
peptide metabolic process GO:0006518 46 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
carbohydrate derivative catabolic process GO:1901136 231 0.025
nitrogen compound transport GO:0071705 271 0.025
spermatogenesis GO:0007283 284 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
cation transmembrane transport GO:0098655 266 0.024
steroid metabolic process GO:0008202 119 0.023
cellular chemical homeostasis GO:0055082 215 0.023
homeostasis of number of cells GO:0048872 210 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
regulation of organelle organization GO:0033043 289 0.023
cellular ketone metabolic process GO:0042180 84 0.023
organic acid biosynthetic process GO:0016053 86 0.023
carboxylic acid catabolic process GO:0046395 51 0.022
cellular amide metabolic process GO:0043603 58 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
regulation of defense response GO:0031347 233 0.022
regulation of protein localization GO:0032880 231 0.021
cellular protein catabolic process GO:0044257 155 0.021
apoptotic signaling pathway GO:0097190 306 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
divalent inorganic cation transport GO:0072511 178 0.021
cellular amino acid catabolic process GO:0009063 25 0.021
cation homeostasis GO:0055080 212 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
purine containing compound metabolic process GO:0072521 311 0.020
coenzyme metabolic process GO:0006732 52 0.020
metal ion homeostasis GO:0055065 189 0.020
cytokine production GO:0001816 319 0.020
regulation of secretion by cell GO:1903530 249 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
regulation of cellular response to stress GO:0080135 159 0.019
lipid biosynthetic process GO:0008610 179 0.019
peptidyl amino acid modification GO:0018193 336 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
organic acid catabolic process GO:0016054 51 0.019
small molecule catabolic process GO:0044282 71 0.019
positive regulation of cell death GO:0010942 224 0.018
inflammatory response GO:0006954 244 0.018
cytoplasmic transport GO:0016482 234 0.018
alpha amino acid biosynthetic process GO:1901607 15 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
regulation of cytokine production GO:0001817 266 0.018
vesicle organization GO:0016050 60 0.018
regulation of proteolysis GO:0030162 164 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
regulation of cell activation GO:0050865 289 0.017
blood vessel morphogenesis GO:0048514 285 0.017
positive regulation of protein modification process GO:0031401 299 0.017
glutathione metabolic process GO:0006749 16 0.017
regulation of intracellular transport GO:0032386 159 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
cell type specific apoptotic process GO:0097285 268 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
regulation of hormone levels GO:0010817 211 0.017
nucleoside metabolic process GO:0009116 246 0.017
carbohydrate homeostasis GO:0033500 128 0.017
cellular ion homeostasis GO:0006873 165 0.017
organic hydroxy compound biosynthetic process GO:1901617 77 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
anion transport GO:0006820 177 0.017
protein maturation GO:0051604 176 0.016
regulation of cell cycle GO:0051726 281 0.016
regulation of kinase activity GO:0043549 249 0.016
heterocycle catabolic process GO:0046700 280 0.016
striated muscle tissue development GO:0014706 293 0.016
regulation of mapk cascade GO:0043408 248 0.016
lateral inhibition GO:0046331 1 0.016
spermatid differentiation GO:0048515 115 0.016
mapk cascade GO:0000165 281 0.016
endomembrane system organization GO:0010256 147 0.016
cellular response to lipid GO:0071396 145 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
response to organonitrogen compound GO:0010243 246 0.016
inorganic cation transmembrane transport GO:0098662 207 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
circulatory system process GO:0003013 197 0.015
positive regulation of cell development GO:0010720 237 0.015
aromatic compound catabolic process GO:0019439 286 0.015
dephosphorylation GO:0016311 129 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
negative regulation of immune system process GO:0002683 209 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
cellular amino acid biosynthetic process GO:0008652 22 0.015
regulation of t cell activation GO:0050863 170 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
leukocyte differentiation GO:0002521 342 0.015
negative regulation of molecular function GO:0044092 258 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
cofactor metabolic process GO:0051186 80 0.015
intracellular protein transport GO:0006886 204 0.015
epidermis development GO:0008544 187 0.015
muscle cell differentiation GO:0042692 261 0.015
regulation of hydrolase activity GO:0051336 246 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
divalent metal ion transport GO:0070838 172 0.014
negative regulation of protein modification process GO:0031400 163 0.014
response to organic cyclic compound GO:0014070 198 0.014
regulation of anatomical structure size GO:0090066 178 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
renal system development GO:0072001 225 0.014
regulation of secretion GO:0051046 274 0.014
regulation of membrane potential GO:0042391 192 0.014
organic anion transport GO:0015711 137 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of response to wounding GO:1903034 189 0.014
fat cell differentiation GO:0045444 160 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
hexose catabolic process GO:0019320 3 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
regulation of transferase activity GO:0051338 263 0.014
response to nutrient levels GO:0031667 109 0.014
organelle assembly GO:0070925 177 0.014
skin development GO:0043588 220 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
t cell activation GO:0042110 289 0.014
response to oxidative stress GO:0006979 123 0.014
response to lipopolysaccharide GO:0032496 128 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
glucose homeostasis GO:0042593 128 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
spermatid development GO:0007286 108 0.014
cellular response to growth factor stimulus GO:0071363 197 0.014
response to growth factor GO:0070848 198 0.014
regulation of vesicle mediated transport GO:0060627 139 0.013
protein oligomerization GO:0051259 67 0.013
sensory perception GO:0007600 245 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of neuron differentiation GO:0045664 281 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of homeostatic process GO:0032844 182 0.013
germ cell development GO:0007281 185 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
organelle fission GO:0048285 170 0.013
response to iron ion GO:0010039 4 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
glucose metabolic process GO:0006006 92 0.013
water soluble vitamin metabolic process GO:0006767 10 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
actin cytoskeleton organization GO:0030036 220 0.013
neuron death GO:0070997 154 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
cellular protein complex assembly GO:0043623 116 0.012
dna metabolic process GO:0006259 303 0.012
blood circulation GO:0008015 195 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
protein localization to membrane GO:0072657 108 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
nuclear transport GO:0051169 139 0.012
lymphocyte proliferation GO:0046651 164 0.012
sterol metabolic process GO:0016125 58 0.012
angiogenesis GO:0001525 201 0.012
sequestering of metal ion GO:0051238 19 0.012
response to extracellular stimulus GO:0009991 127 0.012
regulation of peptidase activity GO:0052547 96 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cellular response to lipopolysaccharide GO:0071222 77 0.012
positive regulation of cell activation GO:0050867 158 0.012
muscle tissue development GO:0060537 308 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
immune effector process GO:0002252 321 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
action potential GO:0001508 78 0.012
cellular response to external stimulus GO:0071496 88 0.012
regulation of system process GO:0044057 200 0.012
locomotory behavior GO:0007626 195 0.012
chemotaxis GO:0006935 247 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
kidney development GO:0001822 213 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
calcium ion transport GO:0006816 159 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
maintenance of location GO:0051235 89 0.011
chromatin organization GO:0006325 206 0.011
membrane fusion GO:0061025 38 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
plasma membrane organization GO:0007009 90 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of protein kinase activity GO:0045859 232 0.011
protein modification by small protein conjugation or removal GO:0070647 207 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
glycerolipid metabolic process GO:0046486 122 0.011
negative regulation of organelle organization GO:0010639 90 0.011
gonad development GO:0008406 141 0.011
glycoprotein metabolic process GO:0009100 116 0.011
myosin filament organization GO:0031033 3 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
regulation of inflammatory response GO:0050727 147 0.011
nuclear division GO:0000280 158 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
organic hydroxy compound transport GO:0015850 93 0.011
ossification GO:0001503 216 0.011
chromatin modification GO:0016568 187 0.011
l ascorbic acid metabolic process GO:0019852 4 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
interspecies interaction between organisms GO:0044419 83 0.011
negative regulation of transferase activity GO:0051348 85 0.011
multicellular organismal signaling GO:0035637 91 0.011
organophosphate catabolic process GO:0046434 232 0.011
rhythmic process GO:0048511 174 0.011
interleukin 8 production GO:0032637 4 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
mitochondrion organization GO:0007005 134 0.010
respiratory tube development GO:0030323 167 0.010
transmission of nerve impulse GO:0019226 76 0.010
cholesterol metabolic process GO:0008203 56 0.010
respiratory system development GO:0060541 190 0.010
response to oxygen levels GO:0070482 62 0.010
regulation of interleukin 8 production GO:0032677 3 0.010
microtubule based process GO:0007017 236 0.010
endocytosis GO:0006897 168 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
nadph regeneration GO:0006740 2 0.010
response to acid chemical GO:0001101 111 0.010
ameboidal type cell migration GO:0001667 128 0.010
innate immune response GO:0045087 157 0.010
epithelial cell proliferation GO:0050673 174 0.010
positive regulation of nervous system development GO:0051962 221 0.010
gland development GO:0048732 330 0.010
regulation of transmembrane transport GO:0034762 128 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
nucleoside catabolic process GO:0009164 206 0.010
development of primary sexual characteristics GO:0045137 143 0.010

Asl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.062
inherited metabolic disorder DOID:655 0 0.031
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
immune system disease DOID:2914 0 0.015
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
central nervous system disease DOID:331 0 0.011
sensory system disease DOID:0050155 0 0.011