Mus musculus

0 known processes

Dkk4

dickkopf homolog 4 (Xenopus laevis)

(Aliases: Dkk-4,MGC25705)

Dkk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.193
cellular amino acid metabolic process GO:0006520 103 0.182
regulation of cellular amine metabolic process GO:0033238 20 0.106
regulation of cellular ketone metabolic process GO:0010565 66 0.098
amine metabolic process GO:0009308 45 0.098
purine nucleotide metabolic process GO:0006163 302 0.091
central nervous system neuron differentiation GO:0021953 162 0.086
nucleobase containing small molecule metabolic process GO:0055086 352 0.083
inorganic cation transmembrane transport GO:0098662 207 0.075
response to organonitrogen compound GO:0010243 246 0.070
negative regulation of cell development GO:0010721 169 0.069
cellular response to cytokine stimulus GO:0071345 189 0.068
epidermis development GO:0008544 187 0.066
negative regulation of phosphate metabolic process GO:0045936 184 0.065
negative regulation of molecular function GO:0044092 258 0.063
ribonucleotide metabolic process GO:0009259 291 0.063
regulation of defense response GO:0031347 233 0.062
regulation of transferase activity GO:0051338 263 0.060
nucleoside phosphate metabolic process GO:0006753 338 0.058
inorganic ion transmembrane transport GO:0098660 234 0.057
myeloid leukocyte differentiation GO:0002573 119 0.056
negative regulation of phosphorylation GO:0042326 166 0.055
purine containing compound metabolic process GO:0072521 311 0.055
potassium ion transmembrane transport GO:0071805 43 0.054
peptidyl amino acid modification GO:0018193 336 0.053
reactive oxygen species metabolic process GO:0072593 84 0.052
nitrogen compound transport GO:0071705 271 0.051
organonitrogen compound biosynthetic process GO:1901566 192 0.051
placenta development GO:0001890 140 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
positive regulation of cellular amine metabolic process GO:0033240 5 0.049
kidney development GO:0001822 213 0.049
regulation of ion transport GO:0043269 215 0.048
potassium ion transport GO:0006813 52 0.048
positive regulation of protein phosphorylation GO:0001934 242 0.046
regulation of inflammatory response GO:0050727 147 0.046
regulation of mapk cascade GO:0043408 248 0.045
regionalization GO:0003002 337 0.045
negative regulation of cell proliferation GO:0008285 296 0.043
cellular chemical homeostasis GO:0055082 215 0.042
nucleotide metabolic process GO:0009117 332 0.042
cellular ketone metabolic process GO:0042180 84 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
response to lipopolysaccharide GO:0032496 128 0.041
myeloid cell differentiation GO:0030099 233 0.040
regulation of reactive oxygen species metabolic process GO:2000377 40 0.040
apoptotic signaling pathway GO:0097190 306 0.039
aromatic compound catabolic process GO:0019439 286 0.038
oxidation reduction process GO:0055114 342 0.038
carbohydrate metabolic process GO:0005975 230 0.038
tube formation GO:0035148 140 0.037
leukocyte differentiation GO:0002521 342 0.036
cation transmembrane transport GO:0098655 266 0.035
cation transport GO:0006812 399 0.035
regulation of nucleotide metabolic process GO:0006140 169 0.035
regulation of organelle organization GO:0033043 289 0.035
regulation of cell cycle GO:0051726 281 0.034
positive regulation of transferase activity GO:0051347 167 0.034
embryonic organ morphogenesis GO:0048562 276 0.034
camera type eye development GO:0043010 266 0.034
regulation of mitotic cell cycle GO:0007346 126 0.034
cellular response to abiotic stimulus GO:0071214 56 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.032
ion transmembrane transport GO:0034220 361 0.032
divalent inorganic cation transport GO:0072511 178 0.032
cellular response to organonitrogen compound GO:0071417 145 0.032
positive regulation of organelle organization GO:0010638 128 0.032
negative regulation of defense response GO:0031348 77 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
cellular response to lipid GO:0071396 145 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.032
cellular potassium ion transport GO:0071804 43 0.031
response to peptide hormone GO:0043434 127 0.031
immune effector process GO:0002252 321 0.031
organophosphate biosynthetic process GO:0090407 122 0.030
positive regulation of cell development GO:0010720 237 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.029
stem cell differentiation GO:0048863 268 0.028
positive regulation of defense response GO:0031349 124 0.028
negative regulation of protein modification process GO:0031400 163 0.028
cellular component assembly involved in morphogenesis GO:0010927 139 0.028
regulation of protein kinase activity GO:0045859 232 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
negative regulation of immune system process GO:0002683 209 0.027
response to acid chemical GO:0001101 111 0.027
spermatogenesis GO:0007283 284 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
forebrain development GO:0030900 302 0.026
regulation of secretion GO:0051046 274 0.026
positive regulation of nervous system development GO:0051962 221 0.026
skin development GO:0043588 220 0.026
response to amino acid GO:0043200 37 0.026
regulation of circadian sleep wake cycle GO:0042749 3 0.026
heterocycle catabolic process GO:0046700 280 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
macromolecule catabolic process GO:0009057 281 0.026
membrane organization GO:0061024 245 0.026
toll like receptor signaling pathway GO:0002224 38 0.025
endocytosis GO:0006897 168 0.025
positive regulation of cell activation GO:0050867 158 0.025
adult behavior GO:0030534 135 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
urogenital system development GO:0001655 261 0.025
mapk cascade GO:0000165 281 0.024
regulation of myeloid cell differentiation GO:0045637 96 0.024
developmental maturation GO:0021700 193 0.024
meiotic nuclear division GO:0007126 115 0.024
protein targeting GO:0006605 143 0.024
b cell activation GO:0042113 161 0.024
sensory organ morphogenesis GO:0090596 242 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
rho protein signal transduction GO:0007266 32 0.023
regulation of cell projection organization GO:0031344 206 0.023
morphogenesis of a branching epithelium GO:0061138 193 0.023
male gamete generation GO:0048232 285 0.023
cellular protein complex assembly GO:0043623 116 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
nucleoside metabolic process GO:0009116 246 0.023
intracellular protein transport GO:0006886 204 0.023
cation homeostasis GO:0055080 212 0.022
cell maturation GO:0048469 127 0.022
actin cytoskeleton organization GO:0030036 220 0.022
transmembrane transport GO:0055085 412 0.022
negative regulation of cell cycle GO:0045786 123 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.022
regulation of metal ion transport GO:0010959 106 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
response to inorganic substance GO:0010035 96 0.022
regulation of organ morphogenesis GO:2000027 144 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
response to peptide GO:1901652 136 0.022
regulation of neuron differentiation GO:0045664 281 0.022
dna metabolic process GO:0006259 303 0.022
ribonucleoside metabolic process GO:0009119 245 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
telencephalon development GO:0021537 186 0.021
response to organic cyclic compound GO:0014070 198 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.021
cell adhesion GO:0007155 329 0.021
cellular response to lipopolysaccharide GO:0071222 77 0.021
defense response to other organism GO:0098542 197 0.021
ras protein signal transduction GO:0007265 77 0.021
positive regulation of ion transport GO:0043270 65 0.021
regulation of establishment of protein localization GO:0070201 181 0.020
anion transport GO:0006820 177 0.020
carbohydrate transport GO:0008643 62 0.020
rhythmic process GO:0048511 174 0.020
carboxylic acid transport GO:0046942 100 0.020
maintenance of location GO:0051235 89 0.020
microtubule based process GO:0007017 236 0.020
t cell activation GO:0042110 289 0.020
dendrite development GO:0016358 115 0.020
nucleotide catabolic process GO:0009166 217 0.020
peptidyl tyrosine modification GO:0018212 145 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
negative regulation of interleukin 6 production GO:0032715 17 0.020
reactive oxygen species biosynthetic process GO:1903409 8 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
leukocyte mediated cytotoxicity GO:0001909 62 0.020
monosaccharide metabolic process GO:0005996 106 0.020
locomotory behavior GO:0007626 195 0.019
organic acid transport GO:0015849 101 0.019
sensory perception of light stimulus GO:0050953 54 0.019
cellular ion homeostasis GO:0006873 165 0.019
regulation of kinase activity GO:0043549 249 0.019
mitotic cell cycle GO:0000278 195 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
sensory perception GO:0007600 245 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
regulation of intracellular transport GO:0032386 159 0.019
response to extracellular stimulus GO:0009991 127 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
synaptic transmission GO:0007268 329 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of reproductive process GO:2000241 66 0.019
stem cell development GO:0048864 219 0.018
gonad development GO:0008406 141 0.018
establishment of protein localization to organelle GO:0072594 118 0.018
hair follicle development GO:0001942 85 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
protein maturation GO:0051604 176 0.018
negative regulation of inflammatory response GO:0050728 61 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.018
positive regulation of protein modification process GO:0031401 299 0.018
regulation of system process GO:0044057 200 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
positive regulation of inflammatory response GO:0050729 47 0.017
organelle assembly GO:0070925 177 0.017
cellular response to inorganic substance GO:0071241 37 0.017
cellular response to peptide GO:1901653 92 0.017
cytoplasmic transport GO:0016482 234 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
cell activation involved in immune response GO:0002263 126 0.017
regulation of hormone levels GO:0010817 211 0.017
regulation of multi organism process GO:0043900 111 0.017
steroid metabolic process GO:0008202 119 0.017
norepinephrine secretion GO:0048243 2 0.017
cellular homeostasis GO:0019725 240 0.017
embryonic placenta development GO:0001892 98 0.016
translation GO:0006412 93 0.016
cellular response to acid chemical GO:0071229 68 0.016
ear development GO:0043583 200 0.016
molting cycle GO:0042303 90 0.016
organic anion transport GO:0015711 137 0.016
cyclic nucleotide metabolic process GO:0009187 59 0.016
actin filament polymerization GO:0030041 44 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
regulation of protein localization GO:0032880 231 0.016
organophosphate catabolic process GO:0046434 232 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
circulatory system process GO:0003013 197 0.016
negative regulation of nervous system development GO:0051961 156 0.016
response to insulin GO:0032868 100 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
positive regulation of cytokine production GO:0001819 174 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
epidermis morphogenesis GO:0048730 33 0.015
response to nutrient levels GO:0031667 109 0.015
glucose transport GO:0015758 56 0.015
cellular protein catabolic process GO:0044257 155 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
positive regulation of response to wounding GO:1903036 66 0.015
regulation of binding GO:0051098 111 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
drug catabolic process GO:0042737 2 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
regulation of cellular component size GO:0032535 121 0.015
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of neuron projection development GO:0010975 169 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
smoothened signaling pathway GO:0007224 105 0.015
negative regulation of transferase activity GO:0051348 85 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
regulation of epidermis development GO:0045682 33 0.015
positive regulation of neuron projection development GO:0010976 79 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.015
circadian rhythm GO:0007623 114 0.015
positive regulation of mapk cascade GO:0043410 170 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
nuclear transport GO:0051169 139 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
hair cycle GO:0042633 90 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
organic acid biosynthetic process GO:0016053 86 0.014
cellular response to external stimulus GO:0071496 88 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
gland development GO:0048732 330 0.014
regulation of protein complex assembly GO:0043254 83 0.014
regulation of t cell activation GO:0050863 170 0.014
renal system development GO:0072001 225 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
positive regulation of intracellular transport GO:0032388 70 0.014
modification dependent protein catabolic process GO:0019941 133 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
positive regulation of kinase activity GO:0033674 155 0.014
interleukin 6 production GO:0032635 58 0.014
calcium ion homeostasis GO:0055074 127 0.014
lateral inhibition GO:0046331 1 0.014
cellular modified amino acid metabolic process GO:0006575 63 0.014
skin morphogenesis GO:0043589 38 0.013
regulation of cell cycle process GO:0010564 160 0.013
oocyte axis specification GO:0007309 2 0.013
gtp catabolic process GO:0006184 143 0.013
defense response to virus GO:0051607 68 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
muscle cell differentiation GO:0042692 261 0.013
meiotic cell cycle process GO:1903046 77 0.013
organelle fission GO:0048285 170 0.013
positive regulation of growth GO:0045927 104 0.013
learning or memory GO:0007611 148 0.013
protein polymerization GO:0051258 57 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
cell growth GO:0016049 130 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
nerve development GO:0021675 67 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
chromatin organization GO:0006325 206 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
lipid transport GO:0006869 98 0.013
regulation of cell motility GO:2000145 236 0.013
phospholipid metabolic process GO:0006644 87 0.013
epithelial cell development GO:0002064 159 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
hexose transport GO:0008645 56 0.012
nuclear division GO:0000280 158 0.012
viral gene expression GO:0019080 3 0.012
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
regulation of cell migration GO:0030334 219 0.012
inflammatory response GO:0006954 244 0.012
connective tissue development GO:0061448 179 0.012
protein import GO:0017038 101 0.012
tissue remodeling GO:0048771 102 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
calcium ion transport GO:0006816 159 0.012
ossification GO:0001503 216 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
neural tube development GO:0021915 160 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
actin filament organization GO:0007015 113 0.012
response to oxygen levels GO:0070482 62 0.012
tube closure GO:0060606 91 0.012
regulation of tumor necrosis factor production GO:0032680 49 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.012
monosaccharide transport GO:0015749 58 0.012
purine nucleotide biosynthetic process GO:0006164 65 0.012
positive regulation of protein transport GO:0051222 93 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
monoamine transport GO:0015844 33 0.012
sequestering of calcium ion GO:0051208 18 0.012
organic hydroxy compound transport GO:0015850 93 0.012
defecation GO:0030421 1 0.012
hormone metabolic process GO:0042445 86 0.012
negative regulation of response to wounding GO:1903035 77 0.012
regulation of interleukin 6 production GO:0032675 55 0.012
lipid biosynthetic process GO:0008610 179 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
protein localization to organelle GO:0033365 185 0.012
purine containing compound catabolic process GO:0072523 213 0.011
cellular lipid metabolic process GO:0044255 323 0.011
multi multicellular organism process GO:0044706 109 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
nuclear import GO:0051170 95 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
regulation of cell growth GO:0001558 91 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
regulation of transmembrane transport GO:0034762 128 0.011
protein import into nucleus GO:0006606 95 0.011
regulation of cell adhesion GO:0030155 154 0.011
negative regulation of kinase activity GO:0033673 81 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
protein oligomerization GO:0051259 67 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
protein catabolic process GO:0030163 221 0.011
heart contraction GO:0060047 93 0.011
mesenchymal cell development GO:0014031 93 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
negative regulation of cytokine production GO:0001818 84 0.011
covalent chromatin modification GO:0016569 163 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
cellular response to amino acid stimulus GO:0071230 29 0.011
regulation of actin filament based process GO:0032970 99 0.011
development of primary male sexual characteristics GO:0046546 88 0.010
leukocyte mediated immunity GO:0002443 174 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
neuromuscular process GO:0050905 99 0.010
notch signaling pathway GO:0007219 71 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
lymphocyte differentiation GO:0030098 242 0.010
regulation of actin nucleation GO:0051125 4 0.010
regulation of t cell proliferation GO:0042129 92 0.010
epithelial tube formation GO:0072175 130 0.010
chromatin modification GO:0016568 187 0.010
epithelial cell proliferation GO:0050673 174 0.010
germ cell development GO:0007281 185 0.010
positive regulation of cell projection organization GO:0031346 95 0.010
development of primary sexual characteristics GO:0045137 143 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.010
protein ubiquitination GO:0016567 171 0.010
glucose homeostasis GO:0042593 128 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
primary neural tube formation GO:0014020 95 0.010

Dkk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.010
disease of cellular proliferation DOID:14566 0 0.010