Mus musculus

24 known processes

Gje1

gap junction protein, epsilon 1

(Aliases: D230044M03Rik,Cx23,Gjf1,Gsfaey12,AEY12)

Gje1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.067
Mouse
cellular amino acid metabolic process GO:0006520 103 0.052
oxidation reduction process GO:0055114 342 0.051
ion transmembrane transport GO:0034220 361 0.047
Mouse
sensory perception GO:0007600 245 0.041
Mouse
cation transport GO:0006812 399 0.041
g protein coupled receptor signaling pathway GO:0007186 243 0.041
cation transmembrane transport GO:0098655 266 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
macromolecule catabolic process GO:0009057 281 0.036
cellular amine metabolic process GO:0044106 44 0.035
inorganic cation transmembrane transport GO:0098662 207 0.034
positive regulation of nervous system development GO:0051962 221 0.031
striated muscle tissue development GO:0014706 293 0.031
Mouse
cellular ketone metabolic process GO:0042180 84 0.030
male gamete generation GO:0048232 285 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
carbohydrate metabolic process GO:0005975 230 0.029
cellular lipid metabolic process GO:0044255 323 0.029
synaptic transmission GO:0007268 329 0.028
Mouse
amine metabolic process GO:0009308 45 0.028
positive regulation of cell development GO:0010720 237 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
regulation of system process GO:0044057 200 0.027
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
peptidyl amino acid modification GO:0018193 336 0.026
spermatogenesis GO:0007283 284 0.025
response to organonitrogen compound GO:0010243 246 0.025
regulation of neuron differentiation GO:0045664 281 0.025
regulation of membrane potential GO:0042391 192 0.025
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
nucleotide metabolic process GO:0009117 332 0.024
anion transport GO:0006820 177 0.024
nucleoside phosphate metabolic process GO:0006753 338 0.024
regulation of transferase activity GO:0051338 263 0.024
organic cyclic compound catabolic process GO:1901361 295 0.023
multicellular organismal signaling GO:0035637 91 0.023
Mouse
apoptotic signaling pathway GO:0097190 306 0.023
sensory organ morphogenesis GO:0090596 242 0.023
Mouse
negative regulation of molecular function GO:0044092 258 0.023
camera type eye development GO:0043010 266 0.022
positive regulation of protein modification process GO:0031401 299 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
aromatic compound catabolic process GO:0019439 286 0.021
muscle tissue development GO:0060537 308 0.021
Mouse
regulation of organelle organization GO:0033043 289 0.021
regulation of defense response GO:0031347 233 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
nitrogen compound transport GO:0071705 271 0.021
organic anion transport GO:0015711 137 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
cytokine production GO:0001816 319 0.021
muscle cell differentiation GO:0042692 261 0.021
leukocyte differentiation GO:0002521 342 0.021
regulation of kinase activity GO:0043549 249 0.021
regulation of ion transport GO:0043269 215 0.021
Mouse
gland development GO:0048732 330 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
response to radiation GO:0009314 165 0.021
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.020
homeostasis of number of cells GO:0048872 210 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
protein ubiquitination GO:0016567 171 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
innate immune response GO:0045087 157 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
regulation of homeostatic process GO:0032844 182 0.019
Mouse
inflammatory response GO:0006954 244 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
purine containing compound metabolic process GO:0072521 311 0.019
cellular chemical homeostasis GO:0055082 215 0.019
cytoplasmic transport GO:0016482 234 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
skeletal system development GO:0001501 356 0.019
Mouse
wound healing GO:0042060 157 0.019
Mouse
skeletal muscle organ development GO:0060538 163 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
transmission of nerve impulse GO:0019226 76 0.019
Mouse
regulation of protein localization GO:0032880 231 0.019
Mouse
regulation of transmembrane transport GO:0034762 128 0.019
Mouse
regulation of cell projection organization GO:0031344 206 0.019
heterocycle catabolic process GO:0046700 280 0.019
cellular response to lipid GO:0071396 145 0.019
cellular homeostasis GO:0019725 240 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
cell adhesion GO:0007155 329 0.019
protein catabolic process GO:0030163 221 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
regulation of cell activation GO:0050865 289 0.018
Mouse
regulation of hydrolase activity GO:0051336 246 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
response to acid chemical GO:0001101 111 0.018
regulation of protein kinase activity GO:0045859 232 0.018
regulation of response to wounding GO:1903034 189 0.018
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.018
regulation of cell cycle GO:0051726 281 0.018
locomotory behavior GO:0007626 195 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
chemotaxis GO:0006935 247 0.017
negative regulation of immune system process GO:0002683 209 0.017
skin development GO:0043588 220 0.017
axonogenesis GO:0007409 274 0.017
lipid biosynthetic process GO:0008610 179 0.017
membrane organization GO:0061024 245 0.017
action potential GO:0001508 78 0.017
Mouse
ear development GO:0043583 200 0.017
Mouse
visual perception GO:0007601 52 0.017
Mouse
microtubule based process GO:0007017 236 0.017
divalent inorganic cation transport GO:0072511 178 0.016
endomembrane system organization GO:0010256 147 0.016
exocytosis GO:0006887 121 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
anatomical structure homeostasis GO:0060249 145 0.016
alcohol metabolic process GO:0006066 116 0.016
immune effector process GO:0002252 321 0.016
nuclear division GO:0000280 158 0.016
regulation of secretion GO:0051046 274 0.016
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.016
regulation of mapk cascade GO:0043408 248 0.016
blood vessel morphogenesis GO:0048514 285 0.016
Mouse
maintenance of location GO:0051235 89 0.016
rhodopsin mediated signaling pathway GO:0016056 4 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
cell type specific apoptotic process GO:0097285 268 0.016
developmental maturation GO:0021700 193 0.015
Mouse
mapk cascade GO:0000165 281 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
divalent metal ion transport GO:0070838 172 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.015
germ cell development GO:0007281 185 0.015
response to organic cyclic compound GO:0014070 198 0.015
monosaccharide metabolic process GO:0005996 106 0.015
placenta development GO:0001890 140 0.015
Mouse
respiratory system development GO:0060541 190 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
mitotic cell cycle GO:0000278 195 0.015
activation of immune response GO:0002253 138 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
negative regulation of cell development GO:0010721 169 0.015
cellular protein complex assembly GO:0043623 116 0.015
regulation of inflammatory response GO:0050727 147 0.015
regulation of cytokine production GO:0001817 266 0.015
circulatory system process GO:0003013 197 0.015
Mouse
protein maturation GO:0051604 176 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
organic acid transport GO:0015849 101 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
cellular protein catabolic process GO:0044257 155 0.014
fat cell differentiation GO:0045444 160 0.014
ras protein signal transduction GO:0007265 77 0.014
organelle fission GO:0048285 170 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
forebrain development GO:0030900 302 0.014
detection of stimulus GO:0051606 84 0.014
Mouse
digestive system development GO:0055123 200 0.014
response to lipopolysaccharide GO:0032496 128 0.014
negative regulation of defense response GO:0031348 77 0.014
fertilization GO:0009566 127 0.014
regulation of neuron projection development GO:0010975 169 0.014
angiogenesis GO:0001525 201 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
multi multicellular organism process GO:0044706 109 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
Mouse
tissue homeostasis GO:0001894 115 0.014
regulation of protein transport GO:0051223 163 0.014
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.014
Mouse
oocyte construction GO:0007308 2 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
dna metabolic process GO:0006259 303 0.014
positive regulation of mapk cascade GO:0043410 170 0.013
blood circulation GO:0008015 195 0.013
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
steroid metabolic process GO:0008202 119 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
hexose metabolic process GO:0019318 98 0.013
thermosensory behavior GO:0040040 1 0.013
glycoprotein metabolic process GO:0009100 116 0.013
regulation of proteolysis GO:0030162 164 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
Mouse
regulation of body fluid levels GO:0050878 162 0.013
lipid localization GO:0010876 126 0.013
t cell activation GO:0042110 289 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
metal ion homeostasis GO:0055065 189 0.013
regulation of cell motility GO:2000145 236 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of cell cycle process GO:0010564 160 0.013
retina development in camera type eye GO:0060041 119 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
intracellular protein transport GO:0006886 204 0.013
small molecule biosynthetic process GO:0044283 132 0.013
cation homeostasis GO:0055080 212 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
cellular response to lipopolysaccharide GO:0071222 77 0.013
anion transmembrane transport GO:0098656 71 0.013
photoreceptor cell development GO:0042461 40 0.013
wnt signaling pathway GO:0016055 188 0.013
regulation of cell migration GO:0030334 219 0.013
response to light stimulus GO:0009416 135 0.013
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
negative regulation of protein modification process GO:0031400 163 0.013
protein processing GO:0016485 163 0.013
mitochondrion organization GO:0007005 134 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
photoreceptor cell differentiation GO:0046530 52 0.013
cognition GO:0050890 149 0.013
detection of abiotic stimulus GO:0009582 60 0.012
Mouse
cellular response to biotic stimulus GO:0071216 92 0.012
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
oocyte axis specification GO:0007309 2 0.012
regionalization GO:0003002 337 0.012
protein localization to organelle GO:0033365 185 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
regulation of hormone levels GO:0010817 211 0.012
meiotic cell cycle GO:0051321 122 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
epithelial cell development GO:0002064 159 0.012
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
respiratory tube development GO:0030323 167 0.012
calcium ion transport GO:0006816 159 0.012
meiotic nuclear division GO:0007126 115 0.012
leukocyte mediated immunity GO:0002443 174 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
nucleoside metabolic process GO:0009116 246 0.012
sequestering of metal ion GO:0051238 19 0.012
cell substrate adhesion GO:0031589 130 0.012
stem cell differentiation GO:0048863 268 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
positive regulation of cell death GO:0010942 224 0.012
adult behavior GO:0030534 135 0.012
regulation of anatomical structure size GO:0090066 178 0.012
Mouse
lymphocyte differentiation GO:0030098 242 0.012
glucose homeostasis GO:0042593 128 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
striated muscle cell development GO:0055002 125 0.012
myotube differentiation GO:0014902 105 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
neuronal action potential GO:0019228 54 0.012
Mouse
regulation of circadian sleep wake cycle GO:0042749 3 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
epithelial cell proliferation GO:0050673 174 0.012
spermatid development GO:0007286 108 0.012
cellular response to acid chemical GO:0071229 68 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of protein catabolic process GO:0042176 108 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
mitochondrion distribution GO:0048311 4 0.011
regulation of secretion by cell GO:1903530 249 0.011
Mouse
production of molecular mediator of immune response GO:0002440 103 0.011
rna processing GO:0006396 105 0.011
positive regulation of transferase activity GO:0051347 167 0.011
cellular response to external stimulus GO:0071496 88 0.011
cellular ion homeostasis GO:0006873 165 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
response to peptide hormone GO:0043434 127 0.011
amide transport GO:0042886 138 0.011
carboxylic acid transport GO:0046942 100 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
neural precursor cell proliferation GO:0061351 121 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
regulation of t cell activation GO:0050863 170 0.011
localization within membrane GO:0051668 4 0.011
single fertilization GO:0007338 82 0.011
myeloid cell differentiation GO:0030099 233 0.011
organophosphate catabolic process GO:0046434 232 0.011
regulation of muscle tissue development GO:1901861 97 0.011
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
cell growth GO:0016049 130 0.011
neuromuscular process GO:0050905 99 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
cell division GO:0051301 120 0.011
sensory perception of light stimulus GO:0050953 54 0.011
Mouse
eye photoreceptor cell development GO:0042462 31 0.011
rho protein signal transduction GO:0007266 32 0.011
lung development GO:0030324 164 0.011
tissue remodeling GO:0048771 102 0.011
Mouse
regulation of peptidase activity GO:0052547 96 0.011
small molecule catabolic process GO:0044282 71 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
muscle cell development GO:0055001 133 0.011
glucose metabolic process GO:0006006 92 0.011
response to extracellular stimulus GO:0009991 127 0.011
carbohydrate homeostasis GO:0033500 128 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
positive regulation of defense response GO:0031349 124 0.011
sequestering of calcium ion GO:0051208 18 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
mrna metabolic process GO:0016071 84 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
mesodermal cell migration GO:0008078 4 0.011
sensory perception of sound GO:0007605 97 0.011
Mouse
muscle contraction GO:0006936 101 0.011
regulation of cellular component size GO:0032535 121 0.011
nucleoside catabolic process GO:0009164 206 0.011
t cell differentiation GO:0030217 174 0.011
regulation of vasculature development GO:1901342 88 0.011
epidermis development GO:0008544 187 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
circadian rhythm GO:0007623 114 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
cardiac chamber development GO:0003205 108 0.011
Mouse
purine nucleotide biosynthetic process GO:0006164 65 0.011
detection of external stimulus GO:0009581 61 0.011
Mouse
fat soluble vitamin biosynthetic process GO:0042362 4 0.011
response to nutrient levels GO:0031667 109 0.010
organelle localization GO:0051640 179 0.010
regulation of cell substrate adhesion GO:0010810 73 0.010
energy derivation by oxidation of organic compounds GO:0015980 77 0.010
spermatid differentiation GO:0048515 115 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
positive regulation of cell motility GO:2000147 116 0.010
ossification GO:0001503 216 0.010
Mouse
ameboidal type cell migration GO:0001667 128 0.010
regulation of multi organism process GO:0043900 111 0.010
cellular alcohol biosynthetic process GO:0044108 3 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
chromatin organization GO:0006325 206 0.010
muscle system process GO:0003012 141 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
peptide transport GO:0015833 133 0.010
skeletal system morphogenesis GO:0048705 203 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
connective tissue development GO:0061448 179 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
eye photoreceptor cell differentiation GO:0001754 41 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
extracellular structure organization GO:0043062 148 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
Mouse
heart contraction GO:0060047 93 0.010
Mouse
sulfur compound metabolic process GO:0006790 100 0.010
negative regulation of nervous system development GO:0051961 156 0.010
extracellular matrix organization GO:0030198 147 0.010

Gje1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
disease of metabolism DOID:0014667 0 0.013
retinal disease DOID:5679 0 0.012
retinal degeneration DOID:8466 0 0.012
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
central nervous system disease DOID:331 0 0.010