Mus musculus

73 known processes

Itgam

integrin alpha M

(Aliases: CR3,CR3A,MAC1,CD11b/CD18,Mac-1,Cd11b,Ly-40,Mac-1a,F730045J24Rik)

Itgam biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neutrophil migration GO:1990266 37 0.637
granulocyte chemotaxis GO:0071621 39 0.481
inflammatory response GO:0006954 244 0.474
leukocyte chemotaxis GO:0030595 69 0.415
cation transport GO:0006812 399 0.395
regulation of secretion GO:0051046 274 0.353
regulation of cell activation GO:0050865 289 0.350
Mouse
regulation of cytokine production GO:0001817 266 0.345
negative regulation of cell migration GO:0030336 59 0.326
Fly
granulocyte migration GO:0097530 43 0.318
g protein coupled receptor signaling pathway GO:0007186 243 0.311
axonogenesis GO:0007409 274 0.311
Fly
regulation of cell motility GO:2000145 236 0.302
Mouse Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.299
regulation of cell migration GO:0030334 219 0.291
Mouse Fly
regulation of exocytosis GO:0017157 61 0.286
angiogenesis GO:0001525 201 0.273
positive regulation of monocyte chemotaxis GO:0090026 2 0.267
cytokine production GO:0001816 319 0.266
chemotaxis GO:0006935 247 0.256
positive regulation of behavior GO:0048520 40 0.248
ameboidal type cell migration GO:0001667 128 0.248
positive regulation of cell migration GO:0030335 109 0.234
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.231
sequestering of metal ion GO:0051238 19 0.223
myeloid leukocyte mediated immunity GO:0002444 42 0.217
amine metabolic process GO:0009308 45 0.206
blood vessel morphogenesis GO:0048514 285 0.196
Mouse
cellular ion homeostasis GO:0006873 165 0.189
positive regulation of protein modification process GO:0031401 299 0.189
membrane organization GO:0061024 245 0.183
immune effector process GO:0002252 321 0.182
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.180
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.179
Mouse
leukocyte migration GO:0050900 124 0.179
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.173
ras protein signal transduction GO:0007265 77 0.167
Mouse
positive regulation of neutrophil chemotaxis GO:0090023 12 0.162
cytokine biosynthetic process GO:0042089 68 0.160
second messenger mediated signaling GO:0019932 73 0.156
Mouse
cellular amine metabolic process GO:0044106 44 0.155
cellular lipid metabolic process GO:0044255 323 0.153
synaptic transmission GO:0007268 329 0.150
Fly
positive regulation of cytokine biosynthetic process GO:0042108 40 0.150
sequestering of calcium ion GO:0051208 18 0.150
leukocyte activation involved in immune response GO:0002366 126 0.148
regulation of map kinase activity GO:0043405 120 0.147
cell adhesion GO:0007155 329 0.142
divalent metal ion transport GO:0070838 172 0.142
negative regulation of cellular protein metabolic process GO:0032269 247 0.139
cytosolic calcium ion transport GO:0060401 48 0.138
regulation of inflammatory response GO:0050727 147 0.136
neutrophil chemotaxis GO:0030593 36 0.135
regulation of secretion by cell GO:1903530 249 0.134
ion transmembrane transport GO:0034220 361 0.133
regulation of cytokine biosynthetic process GO:0042035 59 0.132
negative regulation of cell motility GO:2000146 61 0.131
Fly
regulation of cellular amino acid metabolic process GO:0006521 5 0.131
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.129
calcium mediated signaling GO:0019722 46 0.128
Mouse
myeloid leukocyte migration GO:0097529 57 0.127
positive regulation of mapk cascade GO:0043410 170 0.125
negative regulation of leukocyte mediated immunity GO:0002704 29 0.125
t helper 17 cell chemotaxis GO:0035705 1 0.123
cellular amino acid metabolic process GO:0006520 103 0.121
cell chemotaxis GO:0060326 81 0.120
cellular chemical homeostasis GO:0055082 215 0.119
leukocyte proliferation GO:0070661 172 0.115
regulation of leukocyte mediated immunity GO:0002703 104 0.115
wound healing GO:0042060 157 0.111
Fly
sensory perception GO:0007600 245 0.111
rho protein signal transduction GO:0007266 32 0.111
Mouse
monocyte extravasation GO:0035696 2 0.111
oxidation reduction process GO:0055114 342 0.109
small gtpase mediated signal transduction GO:0007264 97 0.109
Mouse
positive regulation of t cell extravasation GO:2000409 2 0.108
blood circulation GO:0008015 195 0.107
positive regulation of cytokine production GO:0001819 174 0.106
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.104
transmembrane transport GO:0055085 412 0.102
positive regulation of monocyte extravasation GO:2000439 1 0.102
cellular ketone metabolic process GO:0042180 84 0.101
positive regulation of cell motility GO:2000147 116 0.100
Mouse
immune response regulating signaling pathway GO:0002764 125 0.099
regulation of immunological synapse formation GO:2000520 2 0.097
muscle cell differentiation GO:0042692 261 0.097
Mouse
negative regulation of immune system process GO:0002683 209 0.097
myeloid cell differentiation GO:0030099 233 0.097
divalent inorganic cation homeostasis GO:0072507 138 0.096
divalent inorganic cation transport GO:0072511 178 0.095
regulation of monocyte extravasation GO:2000437 2 0.094
positive regulation of secretion by cell GO:1903532 114 0.093
positive regulation of chemotaxis GO:0050921 38 0.090
peptidyl amino acid modification GO:0018193 336 0.089
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.087
circulatory system process GO:0003013 197 0.087
myeloid cell activation involved in immune response GO:0002275 34 0.086
smooth muscle contraction GO:0006939 44 0.086
negative regulation of protein metabolic process GO:0051248 282 0.086
cytokine metabolic process GO:0042107 71 0.085
keratinocyte migration GO:0051546 3 0.085
cellular response to growth factor stimulus GO:0071363 197 0.085
Mouse
response to molecule of bacterial origin GO:0002237 143 0.084
positive regulation of angiogenesis GO:0045766 46 0.084
positive regulation of immunological synapse formation GO:2000522 1 0.084
cognition GO:0050890 149 0.084
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.081
skeletal muscle organ development GO:0060538 163 0.080
cellular homeostasis GO:0019725 240 0.079
adaptive immune response GO:0002250 155 0.079
myeloid leukocyte differentiation GO:0002573 119 0.076
unsaturated fatty acid metabolic process GO:0033559 31 0.074
regulation of protein secretion GO:0050708 82 0.074
regulation of mapk cascade GO:0043408 248 0.074
regulation of cellular ketone metabolic process GO:0010565 66 0.073
regulation of mast cell activation GO:0033003 21 0.073
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.073
cellular calcium ion homeostasis GO:0006874 119 0.073
kidney development GO:0001822 213 0.072
Mouse
macromolecule catabolic process GO:0009057 281 0.071
ossification GO:0001503 216 0.071
regulation of organelle organization GO:0033043 289 0.071
endomembrane system organization GO:0010256 147 0.071
protein catabolic process GO:0030163 221 0.070
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.069
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.069
macrophage activation GO:0042116 27 0.069
regulation of tumor necrosis factor production GO:0032680 49 0.069
regulation of vesicle mediated transport GO:0060627 139 0.068
Mouse
platelet activation GO:0030168 40 0.068
microglial cell activation GO:0001774 3 0.068
cellular divalent inorganic cation homeostasis GO:0072503 127 0.068
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.068
negative regulation of protein modification process GO:0031400 163 0.068
coagulation GO:0050817 78 0.068
negative regulation of intracellular signal transduction GO:1902532 167 0.067
Mouse
cytokine secretion GO:0050663 72 0.067
regulation of ras gtpase activity GO:0032318 88 0.067
positive regulation of granulocyte chemotaxis GO:0071624 12 0.066
regulation of cytokine secretion GO:0050707 61 0.066
positive regulation of kinase activity GO:0033674 155 0.066
inorganic ion transmembrane transport GO:0098660 234 0.066
positive regulation of protein kinase activity GO:0045860 144 0.066
positive regulation of macrophage chemotaxis GO:0010759 5 0.066
positive regulation of cell activation GO:0050867 158 0.065
Mouse
exocytosis GO:0006887 121 0.065
leukocyte differentiation GO:0002521 342 0.065
regulation of protein localization GO:0032880 231 0.064
axon guidance GO:0007411 141 0.064
Fly
regulation of kinase activity GO:0043549 249 0.064
eosinophil activation GO:0043307 1 0.064
positive regulation of transferase activity GO:0051347 167 0.064
regulation of lymphocyte activation GO:0051249 240 0.064
Mouse
regulation of dendritic cell chemotaxis GO:2000508 1 0.064
negative regulation of ras protein signal transduction GO:0046580 18 0.064
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.063
protein secretion GO:0009306 111 0.063
negative regulation of cellular amine metabolic process GO:0033239 1 0.063
helper t cell chemotaxis GO:0035704 1 0.062
cell type specific apoptotic process GO:0097285 268 0.062
calcium ion transport GO:0006816 159 0.061
metal ion homeostasis GO:0055065 189 0.061
regulation of transferase activity GO:0051338 263 0.061
ribonucleotide metabolic process GO:0009259 291 0.060
cation transmembrane transport GO:0098655 266 0.060
positive regulation of cellular amine metabolic process GO:0033240 5 0.060
regulation of t cell costimulation GO:2000523 2 0.060
developmental growth involved in morphogenesis GO:0060560 138 0.060
Fly
regulation of monocyte chemotaxis GO:0090025 3 0.060
negative regulation of cell proliferation GO:0008285 296 0.060
activation of mapk activity GO:0000187 59 0.059
plasma membrane organization GO:0007009 90 0.059
leukocyte mediated immunity GO:0002443 174 0.059
nucleotide metabolic process GO:0009117 332 0.058
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.058
t cell activation GO:0042110 289 0.058
monocarboxylic acid metabolic process GO:0032787 191 0.058
cation homeostasis GO:0055080 212 0.058
regulation of angiogenesis GO:0045765 81 0.057
blood coagulation GO:0007596 76 0.057
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.057
lipid biosynthetic process GO:0008610 179 0.057
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.057
germ cell development GO:0007281 185 0.056
Fly
cellular metal ion homeostasis GO:0006875 151 0.056
digestive tract morphogenesis GO:0048546 147 0.056
regulation of cellular response to stress GO:0080135 159 0.056
regulation of response to wounding GO:1903034 189 0.055
myeloid leukocyte activation GO:0002274 83 0.055
cell substrate adhesion GO:0031589 130 0.055
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.055
Mouse
negative regulation of cell activation GO:0050866 111 0.054
muscle contraction GO:0006936 101 0.054
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.053
mast cell activation involved in immune response GO:0002279 20 0.053
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.053
cell activation involved in immune response GO:0002263 126 0.053
regulation of anatomical structure size GO:0090066 178 0.053
t cell mediated immunity GO:0002456 50 0.053
fat cell differentiation GO:0045444 160 0.053
Mouse
positive regulation of cell development GO:0010720 237 0.053
regulation of defense response GO:0031347 233 0.053
positive regulation of lymphocyte proliferation GO:0050671 70 0.053
Mouse
regulation of vasculature development GO:1901342 88 0.052
defense response to other organism GO:0098542 197 0.052
Mouse
positive regulation of defense response GO:0031349 124 0.052
positive regulation of nervous system development GO:0051962 221 0.051
eosinophil mediated immunity GO:0002447 1 0.051
negative regulation of rho protein signal transduction GO:0035024 7 0.051
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.051
tumor necrosis factor biosynthetic process GO:0042533 10 0.051
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.051
cerebral cortex cell migration GO:0021795 44 0.051
regulation of granulocyte chemotaxis GO:0071622 17 0.051
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.051
positive regulation of neutrophil migration GO:1902624 12 0.051
learning or memory GO:0007611 148 0.050
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.050
neuron migration GO:0001764 122 0.049
Mouse
protein localization to organelle GO:0033365 185 0.049
regulation of t cell extravasation GO:2000407 3 0.049
nitrogen compound transport GO:0071705 271 0.049
regulation of phagocytosis GO:0050764 33 0.049
Mouse
response to light stimulus GO:0009416 135 0.048
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.048
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.048
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.048
regulation of apoptotic signaling pathway GO:2001233 197 0.048
negative regulation of apoptotic signaling pathway GO:2001234 104 0.048
regulation of protein transport GO:0051223 163 0.048
cellular extravasation GO:0045123 17 0.048
embryonic organ morphogenesis GO:0048562 276 0.047
Mouse
maintenance of location GO:0051235 89 0.047
regulation of chemokine production GO:0032642 30 0.047
telencephalon cell migration GO:0022029 55 0.047
regulation of neutrophil chemotaxis GO:0090022 14 0.047
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.047
cell growth GO:0016049 130 0.047
Fly
muscle tissue development GO:0060537 308 0.046
Mouse
response to drug GO:0042493 75 0.046
microglial cell activation involved in immune response GO:0002282 1 0.046
t cell proliferation GO:0042098 120 0.046
icosanoid metabolic process GO:0006690 33 0.046
cellular response to cytokine stimulus GO:0071345 189 0.046
neutrophil mediated immunity GO:0002446 19 0.046
forebrain cell migration GO:0021885 58 0.046
release of sequestered calcium ion into cytosol GO:0051209 42 0.046
urogenital system development GO:0001655 261 0.045
Mouse
tissue homeostasis GO:0001894 115 0.045
Mouse
regulation of homeostatic process GO:0032844 182 0.045
Mouse
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.045
actin filament organization GO:0007015 113 0.044
ribose phosphate metabolic process GO:0019693 291 0.044
leukocyte cell cell adhesion GO:0007159 14 0.044
macrophage chemotaxis GO:0048246 14 0.044
cytoplasmic transport GO:0016482 234 0.044
regulation of epithelial cell proliferation GO:0050678 141 0.044
organelle localization GO:0051640 179 0.043
regulation of endocytosis GO:0030100 69 0.043
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.043
reactive oxygen species biosynthetic process GO:1903409 8 0.043
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.042
Mouse
sensory organ morphogenesis GO:0090596 242 0.042
Mouse
memory GO:0007613 58 0.041
Mouse
cell junction organization GO:0034330 77 0.041
Mouse
positive regulation of chemokine production GO:0032722 22 0.041
sphingolipid metabolic process GO:0006665 45 0.041
protein localization to membrane GO:0072657 108 0.041
calcium ion transport into cytosol GO:0060402 48 0.041
anatomical structure homeostasis GO:0060249 145 0.041
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.041
regulation of establishment of protein localization GO:0070201 181 0.040
epithelial cell development GO:0002064 159 0.040
inorganic cation transmembrane transport GO:0098662 207 0.040
intracellular protein transport GO:0006886 204 0.040
positive regulation of cell projection organization GO:0031346 95 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
positive regulation of alpha beta t cell activation GO:0046635 39 0.039
response to transforming growth factor beta GO:0071559 88 0.039
Mouse
negative regulation of eosinophil degranulation GO:0043310 1 0.039
transmission of nerve impulse GO:0019226 76 0.039
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.039
Mouse
regulation of cell projection organization GO:0031344 206 0.039
stem cell differentiation GO:0048863 268 0.039
organonitrogen compound biosynthetic process GO:1901566 192 0.039
positive regulation of organelle organization GO:0010638 128 0.039
ceramide metabolic process GO:0006672 31 0.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.039
Mouse
regionalization GO:0003002 337 0.039
cytokine mediated signaling pathway GO:0019221 115 0.039
regulation of blood pressure GO:0008217 93 0.038
glial cell differentiation GO:0010001 131 0.038
interleukin 12 secretion GO:0072610 3 0.038
negative regulation of phosphate metabolic process GO:0045936 184 0.038
regulation of protein serine threonine kinase activity GO:0071900 157 0.038
positive regulation of cytokine secretion GO:0050715 41 0.038
muscle system process GO:0003012 141 0.038
ribonucleoside triphosphate catabolic process GO:0009203 199 0.038
inflammatory response to antigenic stimulus GO:0002437 30 0.038
negative regulation of phosphorus metabolic process GO:0010563 184 0.037
regulation of metal ion transport GO:0010959 106 0.037
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.037
lysosome localization GO:0032418 20 0.037
gliogenesis GO:0042063 141 0.037
eosinophil migration GO:0072677 3 0.037
forebrain development GO:0030900 302 0.037
negative regulation of immune effector process GO:0002698 55 0.037
regulated secretory pathway GO:0045055 32 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.036
regulation of hematopoietic stem cell migration GO:2000471 1 0.036
mapk cascade GO:0000165 281 0.036
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.036
Mouse
regulation of body fluid levels GO:0050878 162 0.035
membrane lipid metabolic process GO:0006643 53 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
fatty acid biosynthetic process GO:0006633 41 0.035
positive regulation of cellular catabolic process GO:0031331 148 0.035
epithelial tube morphogenesis GO:0060562 303 0.035
regulation of ossification GO:0030278 112 0.035
regulation of leukocyte apoptotic process GO:2000106 56 0.035
anion transport GO:0006820 177 0.035
gland development GO:0048732 330 0.034
Fly
regulation of type 2 immune response GO:0002828 18 0.034
lymphocyte mediated immunity GO:0002449 139 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.034
regulation of chemotaxis GO:0050920 53 0.034
cell recognition GO:0008037 83 0.034
gtp catabolic process GO:0006184 143 0.034
response to organonitrogen compound GO:0010243 246 0.034
signal transduction in absence of ligand GO:0038034 55 0.034
Mouse
regulation of protein kinase activity GO:0045859 232 0.034
regulation of ion homeostasis GO:2000021 64 0.034
epithelial cell migration GO:0010631 63 0.034
immune complex clearance by monocytes and macrophages GO:0002436 2 0.033
lymphocyte activation involved in immune response GO:0002285 93 0.033
negative regulation of phosphorylation GO:0042326 166 0.033
skeletal system morphogenesis GO:0048705 203 0.033
regulation of regulated secretory pathway GO:1903305 20 0.033
nucleoside catabolic process GO:0009164 206 0.033
epithelium migration GO:0090132 63 0.033
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
positive regulation of secretion GO:0051047 130 0.033
positive regulation of apoptotic process GO:0043065 217 0.033
positive regulation of inflammatory response GO:0050729 47 0.033
glycosyl compound metabolic process GO:1901657 246 0.033
positive regulation of epithelial cell proliferation GO:0050679 68 0.033
neutrophil mediated killing of fungus GO:0070947 3 0.032
regulation of hydrolase activity GO:0051336 246 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
skeletal system development GO:0001501 356 0.032
mesodermal cell migration GO:0008078 4 0.032
positive regulation of immune effector process GO:0002699 107 0.032
multicellular organismal signaling GO:0035637 91 0.032
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.032
activation of immune response GO:0002253 138 0.032
positive regulation of cell adhesion GO:0045785 80 0.032
Mouse
fatty acid metabolic process GO:0006631 121 0.032
action potential GO:0001508 78 0.032
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.032
Fly
positive regulation of lymphocyte activation GO:0051251 140 0.031
Mouse
innate immune response GO:0045087 157 0.031
eosinophil activation involved in immune response GO:0002278 1 0.031
regulation of system process GO:0044057 200 0.031
endothelial cell proliferation GO:0001935 27 0.031
positive regulation of t cell activation GO:0050870 101 0.031
Mouse
regulation of bone resorption GO:0045124 24 0.031
Mouse
cell cell recognition GO:0009988 44 0.030
erk1 and erk2 cascade GO:0070371 77 0.030
Mouse
regulation of neutrophil migration GO:1902622 14 0.030
fatty acid derivative metabolic process GO:1901568 33 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
purine containing compound metabolic process GO:0072521 311 0.030
regulation of interleukin 12 production GO:0032655 30 0.029
regulation of ion transport GO:0043269 215 0.029
regulation of rho protein signal transduction GO:0035023 71 0.029
Mouse
neuron projection guidance GO:0097485 141 0.029
Fly
lymphocyte proliferation GO:0046651 164 0.029
t cell extravasation GO:0072683 4 0.029
positive regulation of intracellular transport GO:0032388 70 0.029
neuronal action potential GO:0019228 54 0.029
developmental cell growth GO:0048588 84 0.029
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
microglia development GO:0014005 2 0.029
regulation of hormone levels GO:0010817 211 0.029
negative regulation of hypersensitivity GO:0002884 3 0.029
positive regulation of adaptive immune response GO:0002821 61 0.029
regulation of cell growth GO:0001558 91 0.029
regulation of cell adhesion GO:0030155 154 0.029
Mouse
defense response to virus GO:0051607 68 0.029
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.029
Fly
positive regulation of nucleotide catabolic process GO:0030813 88 0.029
alpha beta t cell activation GO:0046631 91 0.028
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.028
digestive tract development GO:0048565 190 0.028
positive regulation of leukocyte differentiation GO:1902107 86 0.028
Mouse
cell junction assembly GO:0034329 52 0.028
Mouse
immune complex clearance GO:0002434 2 0.028
response to peptide hormone GO:0043434 127 0.028
striated muscle tissue development GO:0014706 293 0.028
morphogenesis of a branching structure GO:0001763 203 0.027
regulation of ras protein signal transduction GO:0046578 114 0.027
Mouse
neural precursor cell proliferation GO:0061351 121 0.027
response to growth factor GO:0070848 198 0.027
Mouse
positive regulation of gtp catabolic process GO:0033126 85 0.027
purine nucleotide biosynthetic process GO:0006164 65 0.027
cell killing GO:0001906 67 0.027
positive regulation of phagocytosis GO:0050766 26 0.027
small molecule biosynthetic process GO:0044283 132 0.027
regulation of leukocyte proliferation GO:0070663 121 0.027
Mouse
serotonin transport GO:0006837 11 0.027
endocytosis GO:0006897 168 0.027
Mouse Fly
microglia differentiation GO:0014004 2 0.027
cellular carbohydrate metabolic process GO:0044262 119 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
i kappab kinase nf kappab signaling GO:0007249 85 0.027
organic hydroxy compound biosynthetic process GO:1901617 77 0.027
t helper 1 type immune response GO:0042088 25 0.027
nucleoside phosphate biosynthetic process GO:1901293 79 0.026
b cell homeostasis GO:0001782 34 0.026
learning GO:0007612 98 0.026
positive regulation of nucleotide metabolic process GO:0045981 114 0.026
b cell proliferation GO:0042100 53 0.026
positive regulation of map kinase activity GO:0043406 84 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.026
Mouse
organic acid biosynthetic process GO:0016053 86 0.026
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.026
protein kinase b signaling GO:0043491 74 0.026
regulation of lymphocyte proliferation GO:0050670 117 0.026
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.026
negative regulation of regulated secretory pathway GO:1903306 7 0.026
protein targeting GO:0006605 143 0.026
bone resorption GO:0045453 38 0.026
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.025
regulation of fat cell differentiation GO:0045598 81 0.025
lymphocyte differentiation GO:0030098 242 0.025
substrate dependent cell migration cell extension GO:0006930 4 0.025
apoptotic signaling pathway GO:0097190 306 0.025
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.025
positive regulation of endocytosis GO:0045807 42 0.025
acute inflammatory response to antigenic stimulus GO:0002438 12 0.025
regulation of cellular component size GO:0032535 121 0.025
defense response to bacterium GO:0042742 119 0.025
calcium ion homeostasis GO:0055074 127 0.025
regulation of leukocyte degranulation GO:0043300 20 0.025
branching morphogenesis of an epithelial tube GO:0048754 159 0.025
glycerophospholipid metabolic process GO:0006650 71 0.025
actin polymerization or depolymerization GO:0008154 54 0.025
hypersensitivity GO:0002524 10 0.025
peptidyl serine phosphorylation GO:0018105 74 0.025
regulation of protein catabolic process GO:0042176 108 0.025
negative regulation of cytokine production GO:0001818 84 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
hematopoietic stem cell migration GO:0035701 1 0.024
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.024
adult behavior GO:0030534 135 0.024
Fly
response to extracellular stimulus GO:0009991 127 0.024
Mouse
regulation of voltage gated calcium channel activity GO:1901385 4 0.024
regulation of phospholipase c activity GO:1900274 3 0.024
myeloid cell homeostasis GO:0002262 114 0.024
negative regulation of map kinase activity GO:0043407 34 0.024
single organism cell adhesion GO:0098602 156 0.024
regulation of erk1 and erk2 cascade GO:0070372 71 0.024
dendrite development GO:0016358 115 0.024
synapse organization GO:0050808 125 0.024
Fly
myotube differentiation GO:0014902 105 0.024
negative regulation of macrophage apoptotic process GO:2000110 3 0.024
response to oxygen levels GO:0070482 62 0.024
negative regulation of homeostatic process GO:0032845 71 0.024
regulation of membrane potential GO:0042391 192 0.024
leukocyte degranulation GO:0043299 27 0.024
negative regulation of defense response GO:0031348 77 0.024
nucleotide biosynthetic process GO:0009165 78 0.024
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.023
eosinophil degranulation GO:0043308 1 0.023
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.023
positive regulation of jun kinase activity GO:0043507 30 0.023
sensory perception of smell GO:0007608 26 0.023
response to oxidative stress GO:0006979 123 0.023
associative learning GO:0008306 61 0.023
inner ear morphogenesis GO:0042472 101 0.023
Mouse
inflammatory response to wounding GO:0090594 4 0.023
regulation of alpha beta t cell activation GO:0046634 53 0.023
glycoprotein biosynthetic process GO:0009101 89 0.023
reactive nitrogen species metabolic process GO:2001057 0 0.023
fatty acid derivative biosynthetic process GO:1901570 15 0.023
regulation of adaptive immune response GO:0002819 90 0.023
epithelial cell proliferation GO:0050673 174 0.023
regulation of intracellular transport GO:0032386 159 0.023
leukocyte mediated cytotoxicity GO:0001909 62 0.023

Itgam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.143
Human
disease of anatomical entity DOID:7 0 0.143
Human
musculoskeletal system disease DOID:17 0 0.024
Human
connective tissue disease DOID:65 0 0.024
Human