|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.669
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.525
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.492
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.429
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.418
|
Mouse Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.381
|
Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.332
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.307
|
Mouse Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.299
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.291
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.277
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.265
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.261
|
Fly |
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.255
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.253
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.233
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.229
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.224
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.218
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.206
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.204
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.202
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.201
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.182
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.180
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.177
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.177
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.175
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.174
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.174
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.165
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.162
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.162
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.159
|
Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.158
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.158
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.158
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.157
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.154
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.152
|
Fly |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.149
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.148
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.147
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.143
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.142
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.141
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.139
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.137
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.135
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.135
|
Human Mouse Fly |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.134
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.130
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.128
|
Mouse |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.127
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.127
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.127
|
Fly |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.125
|
|
|
|
acid secretion
|
GO:0046717 |
33 |
0.125
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.124
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.122
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.122
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.122
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.122
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.120
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.120
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.120
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.119
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.118
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.115
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.111
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.110
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.109
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.109
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.108
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.104
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.104
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.104
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.103
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.103
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.102
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.102
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.101
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.101
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.101
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.101
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.100
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.100
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.099
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.098
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.097
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.096
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.096
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.095
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.095
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.094
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.094
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.093
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.092
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.092
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.092
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.091
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.091
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.090
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.090
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.090
|
Mouse |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.090
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.089
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.088
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.088
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.087
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.087
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.087
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.087
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.087
|
Fly |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.086
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.086
|
Mouse |
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.085
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.084
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.084
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.083
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.082
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.082
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.081
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.080
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.080
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.080
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.080
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.079
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.078
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.078
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.077
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.077
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.077
|
Mouse |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.074
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.074
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.074
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.074
|
|
|
|
nephric duct formation
|
GO:0072179 |
4 |
0.074
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.073
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.073
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
32 |
0.073
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.072
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.072
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.071
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.070
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.070
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.069
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.069
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.069
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.069
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.069
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.068
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.068
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.068
|
Fly |
|
|
wound healing
|
GO:0042060 |
157 |
0.068
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.067
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.067
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.067
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.067
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.066
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.066
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.066
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.066
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.065
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.065
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.065
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.064
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.064
|
Mouse |
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.063
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.063
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.063
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.062
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.062
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.061
|
Mouse |
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.061
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.061
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.061
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.060
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.060
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.059
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.059
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.059
|
Mouse |
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.058
|
Fly |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.058
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.058
|
Mouse |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.058
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.058
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.058
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.057
|
Fly |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.057
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.057
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.057
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.057
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.056
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.056
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.056
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.056
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.056
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.056
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.056
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.055
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.055
|
Mouse Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.055
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.054
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.054
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.054
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.053
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.053
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.053
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.053
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.053
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.053
|
Mouse |
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.053
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.053
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.052
|
Mouse |
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.052
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.052
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.051
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.051
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.051
|
Mouse |
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.051
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.051
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.051
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.050
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.050
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.049
|
Mouse |
|
|
learning
|
GO:0007612 |
98 |
0.049
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.049
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.048
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.048
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.048
|
Mouse |
|
|
response to radiation
|
GO:0009314 |
165 |
0.048
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.047
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.047
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.047
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.047
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.047
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.046
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.046
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.046
|
|
|
|
negative regulation of inclusion body assembly
|
GO:0090084 |
1 |
0.046
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.046
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.046
|
Mouse |
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.045
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.045
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.045
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.044
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.044
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.044
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.044
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.044
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.044
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.044
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.044
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.043
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.043
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.043
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.043
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.043
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.043
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.043
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.042
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.042
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.042
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.042
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.042
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.041
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.041
|
Fly |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.041
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.041
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.041
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.041
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.041
|
Mouse |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.041
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.041
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.041
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.041
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.040
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.040
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.040
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.040
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.040
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.040
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.039
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.039
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.039
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.039
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.039
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.039
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.039
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.039
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.039
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.038
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.038
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.038
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.038
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.038
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.038
|
Mouse |
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.038
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.038
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.038
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.037
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.037
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.037
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.037
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.037
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.037
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.037
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.037
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.037
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.037
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.037
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.037
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.037
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.036
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.036
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.036
|
|
|
|
regulation of protein complex disassembly
|
GO:0043244 |
28 |
0.036
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.036
|
|
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.036
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.036
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.036
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.036
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.036
|
|
|
|
regulation of protein depolymerization
|
GO:1901879 |
26 |
0.036
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.035
|
Mouse |
|
|
bone resorption
|
GO:0045453 |
38 |
0.035
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.035
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.035
|
Mouse |
|
|
protein import
|
GO:0017038 |
101 |
0.035
|
|
|
|
regulation of heart rate
|
GO:0002027 |
36 |
0.035
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.035
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.035
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.035
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.034
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.034
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.034
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.034
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.034
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.034
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.034
|
Mouse |
|
|
macrophage activation
|
GO:0042116 |
27 |
0.034
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.034
|
Mouse |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.034
|
Mouse |
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.033
|
|
|
|
sphingolipid biosynthetic process
|
GO:0030148 |
26 |
0.033
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.033
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.033
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.033
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.033
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.033
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.033
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.033
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
31 |
0.033
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.033
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.033
|
|
|
|
positive regulation of glycolytic process
|
GO:0045821 |
4 |
0.032
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.032
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.032
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.032
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.032
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.032
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.032
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.031
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.031
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.031
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.031
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.031
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.031
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
25 |
0.031
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.031
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.031
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.031
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.030
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.030
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.030
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.030
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
23 |
0.030
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.030
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.030
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.030
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.030
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.030
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.030
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.029
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.029
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.029
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.029
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.029
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.029
|
|
|
|
positive regulation of renal sodium excretion
|
GO:0035815 |
2 |
0.029
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.029
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.028
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.028
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.028
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.028
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.028
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.028
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.028
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.028
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.028
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.028
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.028
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.028
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.028
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.028
|
Mouse |
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.027
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.027
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.027
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.027
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.027
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.026
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.026
|
Mouse |
|
|
kidney development
|
GO:0001822 |
213 |
0.026
|
Mouse |
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.026
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.026
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.026
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.026
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.026
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.026
|
Mouse |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.026
|
|
|
|
operant conditioning
|
GO:0035106 |
2 |
0.026
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.026
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.026
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.026
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.025
|
Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.025
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.025
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.025
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.025
|
Mouse |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.025
|
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.025
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.025
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.025
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.025
|
|
|
|
bronchiole development
|
GO:0060435 |
3 |
0.025
|
|
|
|
regulation of renal sodium excretion
|
GO:0035813 |
3 |
0.025
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.024
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.024
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.024
|
|
|
|
proteoglycan biosynthetic process
|
GO:0030166 |
20 |
0.024
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.024
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.024
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.024
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.024
|
Human Mouse |
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.024
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.024
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.024
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.024
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.024
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.024
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.024
|
|
|
|
hemostasis
|
GO:0007599 |
78 |
0.023
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.023
|
Mouse |
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.023
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.023
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.023
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.023
|
|
|
|
temperature homeostasis
|
GO:0001659 |
26 |
0.023
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.023
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.023
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.023
|
Mouse |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.023
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.023
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.023
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.023
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
25 |
0.023
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.023
|
Mouse |
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
51 |
0.022
|
|
|
|
renal sodium excretion
|
GO:0035812 |
3 |
0.022
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.022
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.022
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.022
|
Mouse |
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.022
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.022
|
Mouse |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.022
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.022
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.022
|
Mouse |
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.022
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.022
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.022
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.022
|
|
|
|
positive regulation of cyclase activity
|
GO:0031281 |
11 |
0.022
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.022
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.022
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.022
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.021
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.021
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.021
|
Mouse |
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.021
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.021
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.021
|
Human Mouse |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.021
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.021
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.021
|
Fly |
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.021
|
Mouse |
