|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.773
|
Mouse |
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.746
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.670
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.597
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.534
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.461
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.459
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.437
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.379
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.364
|
Mouse |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.358
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.356
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.342
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.340
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.336
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.332
|
Mouse |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.327
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.323
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.307
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.296
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.293
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.289
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.278
|
Fly |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.277
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.271
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.267
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.262
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.261
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.261
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.257
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.245
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.243
|
Mouse Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.241
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.238
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.237
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.233
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.231
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.228
|
|
|
|
sialylation
|
GO:0097503 |
14 |
0.224
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.224
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.220
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.219
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.213
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.206
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
319 |
0.200
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.195
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.189
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.186
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.183
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.181
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.178
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.176
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.175
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.174
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.173
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.167
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.165
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.165
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.165
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.161
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.161
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.160
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.158
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.157
|
Mouse |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.154
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.153
|
Mouse |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.151
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.149
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.148
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.147
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.145
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.142
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.142
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.142
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.141
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.139
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.132
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.132
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.132
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.132
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.131
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.129
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.128
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.126
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.125
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.125
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.124
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.124
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.123
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.122
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.122
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.122
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.120
|
Human |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.120
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.119
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.117
|
Fly |
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.113
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.112
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.110
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.110
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.110
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.108
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.108
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.107
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.107
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.107
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.105
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.105
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.104
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.103
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.103
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.098
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.098
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.098
|
Mouse Fly |
|
|
organelle localization
|
GO:0051640 |
179 |
0.096
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.096
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.096
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.096
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.095
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.093
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.093
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.092
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.091
|
Mouse |
|
|
cell growth
|
GO:0016049 |
130 |
0.091
|
Fly |
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.091
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.091
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.089
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.088
|
Mouse |
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.087
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.087
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.086
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.086
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.085
|
Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.085
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.084
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.083
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.083
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.083
|
Mouse |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.082
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.082
|
Mouse |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.082
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.081
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.081
|
Mouse |
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.081
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.080
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.080
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.080
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.079
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.079
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.079
|
Human |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.077
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.076
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.076
|
Fly |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.076
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.076
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.075
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.075
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.074
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.073
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.073
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.073
|
Fly |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.072
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.072
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.072
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.072
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.071
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.070
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.069
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.069
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.069
|
Mouse Fly |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.069
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.069
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.068
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.068
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.068
|
Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.068
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.067
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.067
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.067
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.067
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.067
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.066
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.065
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.065
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.063
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.063
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.062
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.062
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.062
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.062
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.062
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.062
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.061
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.061
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.061
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.060
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.060
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.060
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.059
|
Mouse |
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.059
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.059
|
Mouse |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.059
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.059
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.058
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.058
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.058
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.058
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.057
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.057
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.055
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.055
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.055
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.055
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.054
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.054
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.054
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.053
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.053
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.053
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.053
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.053
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.053
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.052
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.052
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.052
|
Human Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.052
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.051
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.051
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.051
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.050
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.050
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.050
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.049
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.049
|
Fly |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.049
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.049
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.049
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.048
|
Mouse |
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.048
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.047
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.047
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.047
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.047
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.046
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.046
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.046
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.046
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.046
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.045
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.045
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.045
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.045
|
|
|
|
regulation of interleukin 4 biosynthetic process
|
GO:0045402 |
3 |
0.045
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.045
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.045
|
Mouse |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.044
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.044
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.044
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.044
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.044
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.044
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.043
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.043
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.043
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.043
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.043
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.043
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.042
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.042
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.042
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.042
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.042
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.042
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.042
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.042
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.042
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.041
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.041
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.041
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.041
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.041
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.041
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.041
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.041
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.041
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.041
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.040
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.040
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.040
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.040
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.040
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.040
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.040
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.040
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.039
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.039
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.039
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.039
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.039
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.039
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.039
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.039
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.039
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.038
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.038
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.038
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.038
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.038
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.038
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.038
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.037
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.037
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.037
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.037
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.036
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.036
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.036
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.036
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.036
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.036
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.036
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.036
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.036
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.035
|
Mouse |
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.035
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.035
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.035
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.035
|
Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.035
|
Mouse |
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.035
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.035
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.034
|
Mouse |
|
|
histone modification
|
GO:0016570 |
159 |
0.034
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.034
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.034
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.034
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.034
|
Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.034
|
Fly |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.033
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.033
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.033
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.033
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.033
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.033
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.032
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.032
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.032
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.032
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.032
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.032
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.032
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.031
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.031
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.031
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.031
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.031
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.031
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.030
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.030
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.030
|
|
|
|
memory
|
GO:0007613 |
58 |
0.030
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.030
|
Mouse |
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.030
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.030
|
Mouse |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.030
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.030
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.030
|
Mouse |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.029
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.029
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.029
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.029
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.029
|
Fly |
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.029
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.029
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.029
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.029
|
Fly |
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.029
|
Mouse |
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.029
|
Mouse |
|
|
dna conformation change
|
GO:0071103 |
37 |
0.029
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.029
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.028
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.028
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.028
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.028
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.028
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.028
|
Mouse |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.028
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.028
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.028
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.028
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.028
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.028
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.027
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.027
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.027
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.027
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.027
|
Fly |
|
|
t cell selection
|
GO:0045058 |
34 |
0.027
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.027
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.027
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.027
|
Mouse |
|
|
epidermis development
|
GO:0008544 |
187 |
0.026
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.026
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.026
|
Mouse |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.026
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.026
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.026
|
|
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.026
|
Mouse |
|
|
blood circulation
|
GO:0008015 |
195 |
0.026
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.026
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.026
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.026
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.026
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.026
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.026
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.026
|
Fly |
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
11 |
0.026
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.026
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.026
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.025
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.025
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.025
|
|
|
|
positive regulation of bone resorption
|
GO:0045780 |
13 |
0.025
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.025
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.025
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.025
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.025
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.025
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.025
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.025
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.025
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.024
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.024
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.024
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.024
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.024
|
Mouse |
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.024
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.024
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.024
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.024
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.024
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.024
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.024
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.024
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.024
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.024
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.023
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.023
|
|
|
|
vesicle organization
|
GO:0016050 |
60 |
0.023
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.023
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.023
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.023
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.023
|
Human Mouse |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.023
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.023
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.023
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.023
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.023
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.023
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.023
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.023
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.023
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.023
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.023
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.023
|
|
|
|
post embryonic organ development
|
GO:0048569 |
17 |
0.023
|
Fly |
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.022
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.022
|
Mouse |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.022
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.022
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.022
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.022
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.022
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.022
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.022
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.022
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.022
|
|
|
|
platelet morphogenesis
|
GO:0036344 |
13 |
0.022
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.022
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
81 |
0.022
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.022
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.022
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.022
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.022
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.022
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.022
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.022
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.022
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.022
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.022
|
|
