|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.904
|
Mouse |
|
|
cell junction organization
|
GO:0034330 |
77 |
0.892
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.870
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.812
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.794
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.762
|
Mouse |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.758
|
Fly |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.749
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.704
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.696
|
Human Mouse |
|
|
regionalization
|
GO:0003002 |
337 |
0.672
|
Zebrafish |
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.651
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.614
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.597
|
Zebrafish Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.565
|
Zebrafish Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.559
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.551
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.549
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.544
|
Mouse |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.513
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.484
|
Mouse |
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.456
|
Zebrafish Mouse |
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.443
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.429
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.427
|
Mouse |
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.426
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.420
|
Mouse |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.418
|
Fly |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.416
|
Zebrafish |
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.416
|
Fly |
|
|
axon guidance
|
GO:0007411 |
141 |
0.413
|
Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.412
|
Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.409
|
Zebrafish Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.400
|
Mouse |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.399
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.387
|
Human |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.378
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.366
|
Mouse Fly |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.340
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.339
|
Mouse |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.339
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.330
|
Fly |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.326
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.325
|
Human |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.314
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.312
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.310
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.307
|
|
|
|
cell migration involved in endocardial cushion formation
|
GO:0003273 |
3 |
0.307
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.305
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.300
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.298
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.297
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.289
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.281
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.279
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.272
|
|
|
|
substrate dependent cell migration
|
GO:0006929 |
18 |
0.270
|
Mouse |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.270
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.266
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.260
|
Mouse Fly |
|
|
epidermis development
|
GO:0008544 |
187 |
0.256
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.255
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.254
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.254
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.253
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.252
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.246
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.242
|
Fly |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.234
|
Zebrafish |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.227
|
Fly |
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.224
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.223
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.218
|
Mouse |
|
|
sensory perception
|
GO:0007600 |
245 |
0.217
|
Fly |
|
|
platelet activation
|
GO:0030168 |
40 |
0.216
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.215
|
Zebrafish Fly |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
23 |
0.213
|
Zebrafish |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.208
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.206
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.206
|
Zebrafish Fly |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.204
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.201
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.200
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.199
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.197
|
Fly |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.193
|
Zebrafish Fly |
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.191
|
Fly |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.190
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.189
|
Worm |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.186
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.186
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.185
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.184
|
Worm |
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.184
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.182
|
Human |
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.180
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.179
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.178
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.178
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.178
|
Fly |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.177
|
Fly |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.174
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.174
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.171
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.169
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.168
|
Worm |
|
|
skin development
|
GO:0043588 |
220 |
0.166
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.165
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.165
|
Mouse |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.163
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.162
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.162
|
Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.162
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.158
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.157
|
Mouse |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
1 |
0.157
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.156
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.156
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.155
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.152
|
Mouse |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.152
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.151
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.151
|
Zebrafish Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.149
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.147
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.147
|
Zebrafish Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.146
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.142
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.141
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.137
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.137
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.136
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.134
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.133
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.132
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.130
|
Mouse |
|
|
heart trabecula morphogenesis
|
GO:0061384 |
26 |
0.129
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.128
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.126
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.125
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.125
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.124
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.124
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.124
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.123
|
Worm |
|
|
limb development
|
GO:0060173 |
166 |
0.123
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.121
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.119
|
Fly |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.117
|
Mouse |
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.117
|
Fly |
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.116
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.115
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.115
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.115
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.115
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.114
|
Mouse |
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.111
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.109
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.109
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.108
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.107
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.106
|
Mouse |
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.104
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.104
|
Human |
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.102
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.102
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.101
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.100
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.100
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.099
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.099
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.099
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.097
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.097
|
Mouse |
|
|
hemostasis
|
GO:0007599 |
78 |
0.095
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.094
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.094
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.093
|
Mouse Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.093
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.092
|
Mouse |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.092
|
|
|
|
venous blood vessel development
|
GO:0060841 |
13 |
0.092
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.091
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.091
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.090
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.090
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.089
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.088
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.087
|
Mouse |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.087
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.087
|
|
|
|
fibrinolysis
|
GO:0042730 |
3 |
0.087
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.086
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.086
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.085
|
|
|
|
cell migration involved in sprouting angiogenesis
|
GO:0002042 |
9 |
0.084
|
Zebrafish |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.083
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
65 |
0.082
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.082
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.082
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.081
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.081
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
20 |
0.081
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.080
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.080
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.080
|
|
|
|
heart trabecula formation
|
GO:0060347 |
14 |
0.079
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.079
|
Zebrafish |
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.079
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.078
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.078
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.078
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.078
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.078
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.078
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.078
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.078
|
Fly |
|
|
macromolecule deacylation
|
GO:0098732 |
37 |
0.077
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.077
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.077
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.076
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.076
|
Fly |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.076
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.076
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.076
|
Zebrafish |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.075
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.075
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.075
|
Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.075
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.075
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.075
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
48 |
0.074
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.074
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.074
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.074
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.073
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.073
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.073
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.073
|
Mouse |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.073
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.073
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.072
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.072
|
|
|
|
regulation of axon extension
|
GO:0030516 |
43 |
0.072
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.072
|
Fly |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.072
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.071
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.071
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.071
|
|
|
|
negative regulation of pathway restricted smad protein phosphorylation
|
GO:0060394 |
1 |
0.070
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.070
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.069
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.069
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.069
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.069
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.069
|
Mouse |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.068
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.068
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.068
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.068
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.068
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.068
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.068
|
|
|
|
heparin biosynthetic process
|
GO:0030210 |
2 |
0.068
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.067
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.067
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.067
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.066
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.066
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.066
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.066
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.065
|
Mouse Fly |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.065
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.064
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.064
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.064
|
|
|
|
positive regulation of dna biosynthetic process
|
GO:2000573 |
4 |
0.064
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.064
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.064
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.063
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.063
|
Zebrafish Mouse |
|
|
t cell migration
|
GO:0072678 |
19 |
0.062
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.062
|
Mouse |
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.061
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.061
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.061
|
Mouse |
|
|
cell aging
|
GO:0007569 |
35 |
0.061
|
|
|
|
substrate dependent cell migration cell extension
|
GO:0006930 |
4 |
0.061
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.061
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.060
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.060
|
|
|
|
liposaccharide metabolic process
|
GO:1903509 |
27 |
0.060
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.060
|
Worm |
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.060
|
Fly |
|
|
male gonad development
|
GO:0008584 |
88 |
0.060
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.060
|
Mouse |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
51 |
0.059
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.059
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.059
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.059
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.059
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.058
|
Mouse |
|
|
trabecula morphogenesis
|
GO:0061383 |
40 |
0.058
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.058
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.057
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.057
|
Mouse |
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.057
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.057
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.057
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.057
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.057
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.056
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.056
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.056
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.055
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.055
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.055
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.055
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.055
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.055
|
Fly |
|
|
positive regulation of axon extension
|
GO:0045773 |
20 |
0.054
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.054
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.054
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.054
|
|
|
|
detection of external stimulus
|
GO:0009581 |
61 |
0.054
|
|
|
|
regulation of neurotransmitter transport
|
GO:0051588 |
35 |
0.054
|
|
|
|
trophoblast giant cell differentiation
|
GO:0060707 |
15 |
0.054
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.054
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.053
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.053
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.053
|
|
|
|
cell substrate junction assembly
|
GO:0007044 |
24 |
0.053
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.053
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.053
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.053
|
Worm |
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.052
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.052
|
Mouse |
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.052
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.052
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.052
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.052
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.051
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.051
|
|
|
|
positive regulation of neuron projection regeneration
|
GO:0070572 |
2 |
0.050
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.050
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.050
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
26 |
0.050
|
Zebrafish |
|
|
lung development
|
GO:0030324 |
164 |
0.050
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.050
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.050
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.050
|
|
|
|
central nervous system vasculogenesis
|
GO:0022009 |
3 |
0.050
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.050
|
|
|
|
protein localization to cell junction
|
GO:1902414 |
3 |
0.050
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.049
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.049
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.049
|
Zebrafish |
|
|
organelle localization
|
GO:0051640 |
179 |
0.048
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.048
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.048
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.048
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.048
|
Mouse |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.048
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.048
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.048
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.047
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.047
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.047
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.047
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.047
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.047
|
|
|
|
ventricular septum development
|
GO:0003281 |
42 |
0.047
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.047
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
50 |
0.047
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.047
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.046
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.046
|
Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.046
|
Mouse Worm |
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.046
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.046
|
|
|
|
aminoglycan biosynthetic process
|
GO:0006023 |
15 |
0.045
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.045
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.045
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.045
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.045
|
Mouse |
|
|
cardiac ventricle development
|
GO:0003231 |
83 |
0.045
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.045
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.045
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.045
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.045
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.045
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.045
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.045
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.044
|
|
|
|
cellular response to follicle stimulating hormone stimulus
|
GO:0071372 |
1 |
0.044
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.044
|
Mouse |
|
|
focal adhesion assembly
|
GO:0048041 |
19 |
0.044
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.044
|
Human |
|
|
cell recognition
|
GO:0008037 |
83 |
0.044
|
Fly |
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.044
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.043
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.043
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.043
|
|
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.043
|
|
|
|
establishment of endothelial blood brain barrier
|
GO:0014045 |
3 |
0.043
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.043
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.042
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.042
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.042
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.042
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.042
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.042
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.042
|
Human |
|
|
ossification
|
GO:0001503 |
216 |
0.042
|
|
|
|
learning
|
GO:0007612 |
98 |
0.041
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.041
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.041
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
11 |
0.041
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.041
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.041
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.041
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.041
|
Zebrafish |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.041
|
|
|
|
neuroepithelial cell differentiation
|
GO:0060563 |
37 |
0.041
|
|
|
|
histone deacetylation
|
GO:0016575 |
26 |
0.040
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.040
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.040
|
Mouse |
|
|
nuclear division
|
GO:0000280 |
158 |
0.040
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.040
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.040
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.040
|
Zebrafish |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.039
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.039
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.039
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.039
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.039
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.039
|
Fly |
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.039
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.039
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.039
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.039
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.038
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.038
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.038
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.038
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.038
|
|
|
|
multicellular organismal macromolecule metabolic process
|
GO:0044259 |
19 |
0.038
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.038
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.038
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.038
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.038
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.038
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.037
|
|
|
|
collagen fibril organization
|
GO:0030199 |
32 |
0.037
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.037
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.037
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.037
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.037
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.037
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.036
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.036
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.036
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.036
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.036
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.036
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.036
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.036
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.036
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.035
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.035
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.035
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.035
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
16 |
0.035
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.035
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.035
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.035
|
|
|
|
acetate ester transport
|
GO:1901374 |
2 |
0.035
|
|
|
|
ceramide metabolic process
|
GO:0006672 |
31 |
0.035
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.034
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.034
|
|
|
|
secretory granule organization
|
GO:0033363 |
20 |
0.034
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.034
|
|