Mus musculus

64 known processes

Grin3a

glutamate receptor ionotropic, NMDA3A

(Aliases: A830097C19Rik,mKIAA1973,NMDAR-L,6430537F04,NR3A,KIAA1973)

Grin3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 245 0.074
Mouse
cell adhesion GO:0007155 329 0.065
protein localization to membrane GO:0072657 108 0.056
Mouse
nitrogen compound transport GO:0071705 271 0.055
regulation of neuron differentiation GO:0045664 281 0.053
negative regulation of cell development GO:0010721 169 0.052
cellular chemical homeostasis GO:0055082 215 0.049
axonogenesis GO:0007409 274 0.045
regulation of system process GO:0044057 200 0.043
Mouse
synapse organization GO:0050808 125 0.042
positive regulation of cell development GO:0010720 237 0.042
g protein coupled receptor signaling pathway GO:0007186 243 0.037
positive regulation of nervous system development GO:0051962 221 0.037
regulation of organelle organization GO:0033043 289 0.036
regulation of secretion GO:0051046 274 0.035
locomotory behavior GO:0007626 195 0.034
Mouse
regulation of membrane potential GO:0042391 192 0.033
Mouse
synaptic transmission GO:0007268 329 0.033
Mouse
negative regulation of nervous system development GO:0051961 156 0.032
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.031
regulation of cellular ketone metabolic process GO:0010565 66 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
myeloid cell differentiation GO:0030099 233 0.029
negative regulation of cellular component organization GO:0051129 194 0.028
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
single organism cell adhesion GO:0098602 156 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
cellular homeostasis GO:0019725 240 0.028
positive regulation of neuron differentiation GO:0045666 141 0.027
male gamete generation GO:0048232 285 0.027
blood circulation GO:0008015 195 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.026
regulation of cell adhesion GO:0030155 154 0.026
spermatid differentiation GO:0048515 115 0.026
nucleotide metabolic process GO:0009117 332 0.025
spermatogenesis GO:0007283 284 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
single organismal cell cell adhesion GO:0016337 131 0.025
cellular ketone metabolic process GO:0042180 84 0.025
amide transport GO:0042886 138 0.023
ras protein signal transduction GO:0007265 77 0.023
regulation of neuron projection development GO:0010975 169 0.023
regulation of secretion by cell GO:1903530 249 0.022
generation of precursor metabolites and energy GO:0006091 103 0.022
forebrain development GO:0030900 302 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
regulation of anatomical structure size GO:0090066 178 0.022
glucose homeostasis GO:0042593 128 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
wnt signaling pathway GO:0016055 188 0.021
gland development GO:0048732 330 0.021
peptide hormone secretion GO:0030072 109 0.021
regulation of mapk cascade GO:0043408 248 0.021
compound eye development GO:0048749 1 0.021
carbohydrate homeostasis GO:0033500 128 0.021
regulation of cell activation GO:0050865 289 0.021
positive regulation of cell projection organization GO:0031346 95 0.021
regulation of hormone secretion GO:0046883 88 0.020
ion transmembrane transport GO:0034220 361 0.020
adult behavior GO:0030534 135 0.020
Mouse
amine metabolic process GO:0009308 45 0.020
cell type specific apoptotic process GO:0097285 268 0.020
metal ion homeostasis GO:0055065 189 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
peptide transport GO:0015833 133 0.020
multicellular organismal signaling GO:0035637 91 0.020
purine containing compound metabolic process GO:0072521 311 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
sensory perception GO:0007600 245 0.019
Mouse
neuronal action potential GO:0019228 54 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
transmembrane transport GO:0055085 412 0.019
carbohydrate metabolic process GO:0005975 230 0.019
positive regulation of mapk cascade GO:0043410 170 0.018
response to organic cyclic compound GO:0014070 198 0.018
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.018
Mouse
organic anion transport GO:0015711 137 0.018
regulation of peptide hormone secretion GO:0090276 75 0.018
regulation of blood circulation GO:1903522 93 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
apoptotic signaling pathway GO:0097190 306 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
Mouse
homeostasis of number of cells GO:0048872 210 0.018
epithelial tube morphogenesis GO:0060562 303 0.017
response to nutrient levels GO:0031667 109 0.017
positive regulation of neuron projection development GO:0010976 79 0.017
heart morphogenesis GO:0003007 178 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
skeletal system development GO:0001501 356 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
regulation of cell motility GO:2000145 236 0.017
regulation of cellular amine metabolic process GO:0033238 20 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
lateral line system development GO:0048925 1 0.016
receptor localization to synapse GO:0097120 4 0.016
energy derivation by oxidation of organic compounds GO:0015980 77 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
anion transport GO:0006820 177 0.016
mapk cascade GO:0000165 281 0.016
regulation of hormone levels GO:0010817 211 0.016
negative regulation of neuron differentiation GO:0045665 101 0.016
sensory perception of sound GO:0007605 97 0.015
response to peptide GO:1901652 136 0.015
action potential GO:0001508 78 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.015
cell maturation GO:0048469 127 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
development of primary sexual characteristics GO:0045137 143 0.015
cation transport GO:0006812 399 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
cognition GO:0050890 149 0.015
Mouse
response to organonitrogen compound GO:0010243 246 0.015
Mouse
endomembrane system organization GO:0010256 147 0.014
regulation of homeostatic process GO:0032844 182 0.014
positive regulation of protein modification process GO:0031401 299 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
energy reserve metabolic process GO:0006112 39 0.014
macromolecule catabolic process GO:0009057 281 0.014
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
Mouse
chemotaxis GO:0006935 247 0.014
peptidyl amino acid modification GO:0018193 336 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
peptide secretion GO:0002790 114 0.014
cellular ion homeostasis GO:0006873 165 0.014
cellular amine metabolic process GO:0044106 44 0.014
regulation of cell projection organization GO:0031344 206 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
response to extracellular stimulus GO:0009991 127 0.014
regulation of adiponectin secretion GO:0070163 2 0.014
circulatory system process GO:0003013 197 0.014
cation homeostasis GO:0055080 212 0.014
spinal cord development GO:0021510 81 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
germ cell development GO:0007281 185 0.013
response to peptide hormone GO:0043434 127 0.013
hormone secretion GO:0046879 128 0.013
positive regulation of organelle organization GO:0010638 128 0.013
inter male aggressive behavior GO:0002121 3 0.013
developmental maturation GO:0021700 193 0.013
hindbrain development GO:0030902 128 0.013
cyclic purine nucleotide metabolic process GO:0052652 43 0.013
cell cell adhesion GO:0098609 41 0.013
gliogenesis GO:0042063 141 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
protein catabolic process GO:0030163 221 0.013
Mouse
myelination GO:0042552 74 0.013
cyclic nucleotide biosynthetic process GO:0009190 44 0.013
oxidation reduction process GO:0055114 342 0.013
neuron migration GO:0001764 122 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
nucleoside metabolic process GO:0009116 246 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
regulation of feeding behavior GO:0060259 3 0.013
regulation of peptide secretion GO:0002791 77 0.013
glial cell differentiation GO:0010001 131 0.013
spermatid development GO:0007286 108 0.013
glutamate receptor signaling pathway GO:0007215 35 0.013
mesodermal cell migration GO:0008078 4 0.013
extracellular matrix organization GO:0030198 147 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
negative regulation of protein modification process GO:0031400 163 0.012
telencephalon development GO:0021537 186 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
terminal button organization GO:0072553 3 0.012
lateral inhibition GO:0046331 1 0.012
protein maturation GO:0051604 176 0.012
sensory system development GO:0048880 3 0.012
multicellular organismal response to stress GO:0033555 62 0.012
Mouse
anatomical structure maturation GO:0071695 49 0.012
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.012
insulin secretion GO:0030073 89 0.012
aromatic compound catabolic process GO:0019439 286 0.012
immune effector process GO:0002252 321 0.012
regulation of transferase activity GO:0051338 263 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
regulation of cellular response to stress GO:0080135 159 0.012
stem cell differentiation GO:0048863 268 0.012
cellularization GO:0007349 1 0.012
positive regulation of secretion GO:0051047 130 0.012
regulation of peptide transport GO:0090087 91 0.012
regulation of cellular component size GO:0032535 121 0.012
transmission of nerve impulse GO:0019226 76 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of cytokine production GO:0001817 266 0.012
protein localization to synapse GO:0035418 11 0.012
neural tube development GO:0021915 160 0.012
cellular response to monosaccharide stimulus GO:0071326 47 0.012
heart process GO:0003015 94 0.012
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.012
regulation of extent of cell growth GO:0061387 52 0.011
t cell activation GO:0042110 289 0.011
negative regulation of bone trabecula formation GO:1900155 1 0.011
regulation of protein catabolic process GO:0042176 108 0.011
Mouse
purine nucleotide biosynthetic process GO:0006164 65 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
olfactory learning GO:0008355 2 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
rho protein signal transduction GO:0007266 32 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.011
exocytosis GO:0006887 121 0.011
cellular response to lipid GO:0071396 145 0.011
negative regulation of cell projection organization GO:0031345 56 0.011
vascular process in circulatory system GO:0003018 62 0.011
muscle contraction GO:0006936 101 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
camp biosynthetic process GO:0006171 31 0.011
cellular glucan metabolic process GO:0006073 32 0.011
ribose phosphate biosynthetic process GO:0046390 59 0.011
cellular protein catabolic process GO:0044257 155 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
neuromuscular process controlling balance GO:0050885 59 0.011
Mouse
response to radiation GO:0009314 165 0.011
Mouse
synaptic vesicle localization GO:0097479 59 0.011
response to acid chemical GO:0001101 111 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
rhythmic process GO:0048511 174 0.011
Rat
tube formation GO:0035148 140 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
regulation of axon extension GO:0030516 43 0.011
cellular response to glucose stimulus GO:0071333 45 0.011
calcium ion homeostasis GO:0055074 127 0.011
postsynaptic membrane organization GO:0001941 18 0.010
positive regulation of growth GO:0045927 104 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
hexose transport GO:0008645 56 0.010
striated muscle tissue development GO:0014706 293 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
morphogenesis of a branching epithelium GO:0061138 193 0.010
regulation of proteolysis GO:0030162 164 0.010
cation transmembrane transport GO:0098655 266 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
cell cell junction organization GO:0045216 72 0.010
muscle system process GO:0003012 141 0.010
protein localization to juxtaparanode region of axon GO:0071205 4 0.010
muscle tissue development GO:0060537 308 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
positive regulation of creb transcription factor activity GO:0032793 4 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
organelle fission GO:0048285 170 0.010
sensory organ morphogenesis GO:0090596 242 0.010
microtubule based process GO:0007017 236 0.010
regulation of ras protein signal transduction GO:0046578 114 0.010
dephosphorylation GO:0016311 129 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
formation of organ boundary GO:0010160 1 0.010
neuron projection guidance GO:0097485 141 0.010
positive regulation of map kinase activity GO:0043406 84 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.010
establishment of vesicle localization GO:0051650 81 0.010

Grin3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
central nervous system disease DOID:331 0 0.017
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
brain disease DOID:936 0 0.012