Mus musculus

0 known processes

Chaf1b

chromatin assembly factor 1, subunit B (p60)

(Aliases: CAF1A,CAF-Ip60,MPHOSPH7,CAF1,C76145,2600017H24Rik,CAF1P60,CAF-I p60)

Chaf1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna endoreduplication GO:0042023 4 0.368
dna metabolic process GO:0006259 303 0.277
Human Yeast
mitotic cell cycle GO:0000278 195 0.231
Zebrafish
macromolecule catabolic process GO:0009057 281 0.198
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.167
cellular amino acid metabolic process GO:0006520 103 0.155
microtubule based process GO:0007017 236 0.154
nuclear division GO:0000280 158 0.154
establishment of organelle localization GO:0051656 122 0.151
mitotic cell cycle process GO:1903047 159 0.142
regulation of cell cycle process GO:0010564 160 0.141
meiotic nuclear division GO:0007126 115 0.134
cellular response to dna damage stimulus GO:0006974 207 0.134
regulation of cell cycle GO:0051726 281 0.134
metaphase plate congression GO:0051310 2 0.116
negative regulation of mitotic cell cycle GO:0045930 58 0.114
negative regulation of cell cycle GO:0045786 123 0.108
organelle localization GO:0051640 179 0.107
dna repair GO:0006281 107 0.107
regulation of organelle organization GO:0033043 289 0.104
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.097
heterocycle catabolic process GO:0046700 280 0.090
apoptotic signaling pathway GO:0097190 306 0.086
regulation of protein kinase activity GO:0045859 232 0.081
microtubule cytoskeleton organization GO:0000226 157 0.081
meiotic cell cycle process GO:1903046 77 0.078
regulation of chromosome organization GO:0033044 83 0.076
negative regulation of cell cycle phase transition GO:1901988 48 0.076
aromatic compound catabolic process GO:0019439 286 0.076
cellular ketone metabolic process GO:0042180 84 0.073
positive regulation of cell cycle process GO:0090068 61 0.070
regulation of protein localization GO:0032880 231 0.069
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
spindle assembly involved in female meiosis GO:0007056 3 0.068
gland development GO:0048732 330 0.067
protein processing GO:0016485 163 0.065
dna integrity checkpoint GO:0031570 28 0.065
regulation of transferase activity GO:0051338 263 0.063
meiotic cell cycle GO:0051321 122 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.062
chromosome segregation GO:0007059 48 0.060
gonad development GO:0008406 141 0.059
positive regulation of cell cycle GO:0045787 92 0.057
female meiosis chromosome segregation GO:0016321 1 0.056
regulation of mitotic cell cycle GO:0007346 126 0.054
peptidyl amino acid modification GO:0018193 336 0.054
regulation of proteolysis GO:0030162 164 0.054
establishment or maintenance of cell polarity GO:0007163 86 0.054
regulation of kinase activity GO:0043549 249 0.053
regulation of cellular ketone metabolic process GO:0010565 66 0.053
development of primary sexual characteristics GO:0045137 143 0.052
cellular amine metabolic process GO:0044106 44 0.052
regulation of cellular response to stress GO:0080135 159 0.052
organelle assembly GO:0070925 177 0.052
nuclear membrane organization GO:0071763 4 0.051
centrosome duplication GO:0051298 16 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
regulation of cell division GO:0051302 76 0.049
posttranscriptional regulation of gene expression GO:0010608 155 0.049
cellular component assembly involved in morphogenesis GO:0010927 139 0.048
amine metabolic process GO:0009308 45 0.047
muscle cell differentiation GO:0042692 261 0.044
cell cycle checkpoint GO:0000075 47 0.043
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.042
positive regulation of organelle organization GO:0010638 128 0.042
regulation of cell cycle phase transition GO:1901987 77 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.042
organelle fission GO:0048285 170 0.042
dna dependent dna replication GO:0006261 24 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.041
double strand break repair GO:0006302 48 0.041
anatomical structure homeostasis GO:0060249 145 0.041
cell fate commitment GO:0045165 210 0.040
endocytosis GO:0006897 168 0.040
regulation of mitosis GO:0007088 29 0.040
negative regulation of cellular component organization GO:0051129 194 0.040
nuclear dna replication GO:0033260 3 0.039
maintenance of location GO:0051235 89 0.039
endomembrane system organization GO:0010256 147 0.039
regulation of t cell activation GO:0050863 170 0.038
histone modification GO:0016570 159 0.038
mitotic nuclear division GO:0007067 48 0.038
establishment of spindle localization GO:0051293 19 0.037
dna recombination GO:0006310 92 0.037
chromatin organization GO:0006325 206 0.036
Human Yeast
stem cell differentiation GO:0048863 268 0.036
positive regulation of protein kinase activity GO:0045860 144 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
reactive oxygen species metabolic process GO:0072593 84 0.036
purine nucleotide metabolic process GO:0006163 302 0.036
positive regulation of transferase activity GO:0051347 167 0.035
regulation of anatomical structure size GO:0090066 178 0.035
leukocyte proliferation GO:0070661 172 0.034
positive regulation of protein modification process GO:0031401 299 0.034
wnt signaling pathway GO:0016055 188 0.034
myosin filament organization GO:0031033 3 0.034
negative regulation of immune system process GO:0002683 209 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
negative regulation of organelle organization GO:0010639 90 0.033
cellular protein complex assembly GO:0043623 116 0.032
negative regulation of cell proliferation GO:0008285 296 0.032
protein catabolic process GO:0030163 221 0.032
organic cyclic compound catabolic process GO:1901361 295 0.032
dna replication initiation GO:0006270 5 0.032
molting cycle GO:0042303 90 0.032
mitotic cell cycle checkpoint GO:0007093 31 0.031
muscle cell development GO:0055001 133 0.031
protein maturation GO:0051604 176 0.031
negative regulation of protein metabolic process GO:0051248 282 0.030
cellular lipid metabolic process GO:0044255 323 0.030
mapk cascade GO:0000165 281 0.030
nucleotide metabolic process GO:0009117 332 0.030
regulation of lymphocyte apoptotic process GO:0070228 41 0.029
cell cycle g1 s phase transition GO:0044843 57 0.029
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
regulation of mitotic cell cycle phase transition GO:1901990 73 0.029
positive regulation of mapk cascade GO:0043410 170 0.029
regulation of cellular component size GO:0032535 121 0.028
anion transport GO:0006820 177 0.028
negative regulation of molecular function GO:0044092 258 0.028
germ cell development GO:0007281 185 0.028
t cell proliferation GO:0042098 120 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
blood vessel morphogenesis GO:0048514 285 0.027
myosin filament assembly GO:0031034 2 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
regulation of nuclear cell cycle dna replication GO:0033262 2 0.027
striated muscle myosin thick filament assembly GO:0071688 1 0.026
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.026
stem cell maintenance GO:0019827 130 0.026
t cell activation GO:0042110 289 0.026
digestive system development GO:0055123 200 0.026
leukocyte differentiation GO:0002521 342 0.025
regulation of protein secretion GO:0050708 82 0.025
regulation of secretion GO:0051046 274 0.025
positive regulation of cell development GO:0010720 237 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.025
myeloid cell differentiation GO:0030099 233 0.025
covalent chromatin modification GO:0016569 163 0.024
response to inorganic substance GO:0010035 96 0.024
cellular response to biotic stimulus GO:0071216 92 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
immune effector process GO:0002252 321 0.024
stem cell development GO:0048864 219 0.024
regulation of binding GO:0051098 111 0.024
purine containing compound metabolic process GO:0072521 311 0.024
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.024
regulation of cell motility GO:2000145 236 0.024
cell division GO:0051301 120 0.023
oxidation reduction process GO:0055114 342 0.023
neural tube development GO:0021915 160 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
protein dna complex subunit organization GO:0071824 28 0.023
Human Yeast
ribose phosphate metabolic process GO:0019693 291 0.022
spindle localization GO:0051653 22 0.022
lymphocyte differentiation GO:0030098 242 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
negative regulation of protein modification process GO:0031400 163 0.022
cell type specific apoptotic process GO:0097285 268 0.022
regulation of endopeptidase activity GO:0052548 89 0.022
negative regulation of protein processing GO:0010955 79 0.022
fertilization GO:0009566 127 0.022
striated muscle tissue development GO:0014706 293 0.022
adaptive immune response GO:0002250 155 0.022
regulation of cytokine production GO:0001817 266 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
t cell differentiation in thymus GO:0033077 77 0.021
protein import GO:0017038 101 0.021
regulation of hydrolase activity GO:0051336 246 0.021
protein polymerization GO:0051258 57 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
actin filament polymerization GO:0030041 44 0.021
response to cell cycle checkpoint signaling GO:0072396 1 0.021
organic anion transport GO:0015711 137 0.021
protein targeting GO:0006605 143 0.021
regulation of cell activation GO:0050865 289 0.021
hepaticobiliary system development GO:0061008 67 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.020
cellular response to lipid GO:0071396 145 0.020
multicellular organism growth GO:0035264 161 0.020
negative regulation of cell development GO:0010721 169 0.020
cytokine production GO:0001816 319 0.020
regulation of protein transport GO:0051223 163 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
cytokinetic process GO:0032506 2 0.020
mitotic chromosome condensation GO:0007076 1 0.020
cell growth GO:0016049 130 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
embryonic epithelial tube formation GO:0001838 130 0.020
regulation of mitotic sister chromatid segregation GO:0033047 12 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
homeostasis of number of cells GO:0048872 210 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
respiratory tube development GO:0030323 167 0.019
negative regulation of mitosis GO:0045839 10 0.019
intrinsic apoptotic signaling pathway GO:0097193 132 0.019
negative regulation of cell cycle process GO:0010948 69 0.018
glial cell differentiation GO:0010001 131 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
epithelial cell development GO:0002064 159 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
synapsis GO:0007129 34 0.018
positive regulation of nervous system development GO:0051962 221 0.018
blastocyst development GO:0001824 80 0.018
centrosome cycle GO:0007098 23 0.018
g1 s transition of mitotic cell cycle GO:0000082 57 0.018
male gamete generation GO:0048232 285 0.018
cell junction organization GO:0034330 77 0.017
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.017
meiosis i GO:0007127 60 0.017
dephosphorylation GO:0016311 129 0.017
t cell differentiation GO:0030217 174 0.017
positive regulation of kinase activity GO:0033674 155 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
positive regulation of t cell activation GO:0050870 101 0.017
cilium morphogenesis GO:0060271 102 0.017
spermatogenesis GO:0007283 284 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
gene silencing GO:0016458 38 0.017
protein modification by small protein conjugation GO:0032446 187 0.017
muscle tissue development GO:0060537 308 0.017
recombinational repair GO:0000725 21 0.017
protein localization to organelle GO:0033365 185 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
spindle assembly involved in mitosis GO:0090307 4 0.016
protein depolymerization GO:0051261 34 0.016
membrane organization GO:0061024 245 0.016
camera type eye development GO:0043010 266 0.016
Zebrafish
nucleocytoplasmic transport GO:0006913 139 0.016
nuclear envelope organization GO:0006998 11 0.016
ras protein signal transduction GO:0007265 77 0.016
positive regulation of cell activation GO:0050867 158 0.016
regulation of t cell proliferation GO:0042129 92 0.016
regulation of protein stability GO:0031647 52 0.016
organophosphate catabolic process GO:0046434 232 0.016
positive regulation of cell cycle phase transition GO:1901989 17 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.015
mitotic cytokinesis GO:0000281 4 0.015
mitotic sister chromatid separation GO:0051306 9 0.015
nucleus organization GO:0006997 45 0.015
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
cytoplasmic transport GO:0016482 234 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
developmental maturation GO:0021700 193 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
positive regulation of g0 to g1 transition GO:0070318 2 0.015
positive regulation of mitotic cell cycle GO:0045931 41 0.015
liver development GO:0001889 66 0.015
digestive tract morphogenesis GO:0048546 147 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
cellular response to inorganic substance GO:0071241 37 0.015
response to extracellular stimulus GO:0009991 127 0.015
ossification GO:0001503 216 0.015
cell aging GO:0007569 35 0.015
regulation of defense response GO:0031347 233 0.015
striated muscle cell development GO:0055002 125 0.015
b cell activation GO:0042113 161 0.015
response to lipopolysaccharide GO:0032496 128 0.015
primary neural tube formation GO:0014020 95 0.015
regulation of neuron differentiation GO:0045664 281 0.014
dna packaging GO:0006323 30 0.014
Human Yeast
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.014
leukocyte mediated immunity GO:0002443 174 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.014
single organism nuclear import GO:1902593 95 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
cell maturation GO:0048469 127 0.014
actin cytoskeleton organization GO:0030036 220 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
negative regulation of sister chromatid segregation GO:0033046 7 0.014
nuclear transport GO:0051169 139 0.014
localization within membrane GO:0051668 4 0.014
regulation of protein catabolic process GO:0042176 108 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
positive regulation of cell death GO:0010942 224 0.014
cellularization GO:0007349 1 0.014
intracellular protein transport GO:0006886 204 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.013
digestive tract development GO:0048565 190 0.013
purine nucleobase biosynthetic process GO:0009113 3 0.013
chromatin modification GO:0016568 187 0.013
b cell apoptotic process GO:0001783 19 0.013
sister chromatid cohesion GO:0007062 12 0.013
nucleoside catabolic process GO:0009164 206 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
epithelial cell proliferation GO:0050673 174 0.013
intestinal epithelial structure maintenance GO:0060729 4 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
dna biosynthetic process GO:0071897 22 0.013
cell cycle switching GO:0060184 1 0.013
srebp signaling pathway GO:0032933 4 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
lipid localization GO:0010876 126 0.013
mitotic sister chromatid segregation GO:0000070 14 0.013
centrosome organization GO:0051297 26 0.013
epithelial tube formation GO:0072175 130 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of nuclear division GO:0051783 56 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
response to acid chemical GO:0001101 111 0.013
b cell activation involved in immune response GO:0002312 50 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
glycerolipid metabolic process GO:0046486 122 0.012
positive regulation of lymphocyte proliferation GO:0050671 70 0.012
rho protein signal transduction GO:0007266 32 0.012
lipid biosynthetic process GO:0008610 179 0.012
rhythmic process GO:0048511 174 0.012
peptidyl serine modification GO:0018209 83 0.012
regulation of leukocyte apoptotic process GO:2000106 56 0.012
stress activated mapk cascade GO:0051403 80 0.012
regulation of exit from mitosis GO:0007096 1 0.012
spindle assembly involved in meiosis GO:0090306 4 0.012
cardiocyte differentiation GO:0035051 87 0.012
stem cell proliferation GO:0072089 117 0.012
monocarboxylic acid biosynthetic process GO:0072330 61 0.012
meiotic chromosome segregation GO:0045132 19 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
erythrocyte differentiation GO:0030218 88 0.012
positive regulation of t cell proliferation GO:0042102 52 0.012
negative regulation of protein transport GO:0051224 46 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
respiratory system development GO:0060541 190 0.012
signal transduction by p53 class mediator GO:0072331 51 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
reciprocal dna recombination GO:0035825 16 0.012
neural tube formation GO:0001841 108 0.011
lymphocyte apoptotic process GO:0070227 54 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of mapk cascade GO:0043408 248 0.011
activation of immune response GO:0002253 138 0.011
lung development GO:0030324 164 0.011
response to steroid hormone GO:0048545 56 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
female meiotic division GO:0007143 21 0.011
lymphocyte proliferation GO:0046651 164 0.011
small molecule biosynthetic process GO:0044283 132 0.011
rna processing GO:0006396 105 0.011
leukocyte migration GO:0050900 124 0.011
cellular homeostasis GO:0019725 240 0.011
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.011
female gamete generation GO:0007292 74 0.011
oocyte construction GO:0007308 2 0.011
dna replication GO:0006260 52 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
regulation of chromatin organization GO:1902275 57 0.011
single fertilization GO:0007338 82 0.011
response to organonitrogen compound GO:0010243 246 0.011
regulation of response to wounding GO:1903034 189 0.011
cellular response to sterol depletion GO:0071501 4 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
regulation of cellular catabolic process GO:0031329 242 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
sister chromatid segregation GO:0000819 20 0.011
tube formation GO:0035148 140 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.011
lateral inhibition GO:0046331 1 0.011
cellular response to external stimulus GO:0071496 88 0.011
regulation of inflammatory response GO:0050727 147 0.010
negative regulation of proteolysis GO:0045861 74 0.010
cation transport GO:0006812 399 0.010
positive regulation of cytokine production GO:0001819 174 0.010
t cell apoptotic process GO:0070231 39 0.010
carboxylic acid transport GO:0046942 100 0.010
regulation of dna dependent dna replication GO:0090329 8 0.010
leukocyte apoptotic process GO:0071887 71 0.010
nucleus localization GO:0051647 20 0.010
cytokine biosynthetic process GO:0042089 68 0.010
developmental cell growth GO:0048588 84 0.010
positive regulation of growth GO:0045927 104 0.010
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.010
wound healing GO:0042060 157 0.010
regulation of system process GO:0044057 200 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
multicellular organismal aging GO:0010259 24 0.010
cleavage furrow formation GO:0036089 2 0.010

Chaf1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.037
disease of cellular proliferation DOID:14566 0 0.037
organ system cancer DOID:0050686 0 0.037
disease of metabolism DOID:0014667 0 0.031
inherited metabolic disorder DOID:655 0 0.031
gastrointestinal system cancer DOID:3119 0 0.017
intestinal cancer DOID:10155 0 0.012
large intestine cancer DOID:5672 0 0.012