Mus musculus

7 known processes

Ptpru

protein tyrosine phosphatase, receptor type, U

(Aliases: R-PTP-psi,PTPlambda,Ptpf,Pcp2,PTP-lambda,Ftp-1,PCP-2,R-PTP-U,Ptprl,RPTPlambda,PTP)

Ptpru biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 166 0.392
cellular amino acid metabolic process GO:0006520 103 0.349
epithelial tube morphogenesis GO:0060562 303 0.327
hindbrain development GO:0030902 128 0.288
Mouse
skeletal system development GO:0001501 356 0.275
negative regulation of growth GO:0045926 99 0.270
central nervous system neuron differentiation GO:0021953 162 0.265
primary neural tube formation GO:0014020 95 0.261
axonogenesis GO:0007409 274 0.261
regulation of anatomical structure size GO:0090066 178 0.260
Mouse
regionalization GO:0003002 337 0.254
cell type specific apoptotic process GO:0097285 268 0.249
organic hydroxy compound metabolic process GO:1901615 203 0.239
chemotaxis GO:0006935 247 0.230
camera type eye development GO:0043010 266 0.223
negative regulation of nervous system development GO:0051961 156 0.198
negative regulation of cell development GO:0010721 169 0.193
purine nucleotide metabolic process GO:0006163 302 0.187
blood circulation GO:0008015 195 0.186
Mouse
regulation of neuron projection development GO:0010975 169 0.182
Mouse
cation homeostasis GO:0055080 212 0.181
positive regulation of cellular catabolic process GO:0031331 148 0.181
cerebellum development GO:0021549 77 0.170
Mouse
cellular ketone metabolic process GO:0042180 84 0.167
skin development GO:0043588 220 0.164
regulation of cellular response to stress GO:0080135 159 0.163
Mouse
amine metabolic process GO:0009308 45 0.163
morphogenesis of a branching structure GO:0001763 203 0.161
developmental maturation GO:0021700 193 0.160
regulation of hydrolase activity GO:0051336 246 0.160
appendage morphogenesis GO:0035107 149 0.156
locomotory behavior GO:0007626 195 0.149
neural tube closure GO:0001843 90 0.148
rho protein signal transduction GO:0007266 32 0.147
negative regulation of cell growth GO:0030308 44 0.145
skeletal system morphogenesis GO:0048705 203 0.145
connective tissue development GO:0061448 179 0.145
embryonic organ morphogenesis GO:0048562 276 0.142
renal system process GO:0003014 48 0.141
branching morphogenesis of an epithelial tube GO:0048754 159 0.141
striated muscle tissue development GO:0014706 293 0.140
embryonic epithelial tube formation GO:0001838 130 0.139
nucleoside phosphate metabolic process GO:0006753 338 0.139
ras protein signal transduction GO:0007265 77 0.137
response to peptide GO:1901652 136 0.134
urogenital system development GO:0001655 261 0.131
ribonucleoside triphosphate catabolic process GO:0009203 199 0.131
regulation of cellular catabolic process GO:0031329 242 0.130
neuron migration GO:0001764 122 0.130
t cell activation GO:0042110 289 0.129
regulation of organ morphogenesis GO:2000027 144 0.128
segmentation GO:0035282 93 0.128
wnt signaling pathway GO:0016055 188 0.127
Human
muscle cell differentiation GO:0042692 261 0.127
regulation of cellular amine metabolic process GO:0033238 20 0.127
negative regulation of axon extension GO:0030517 19 0.125
purine ribonucleotide metabolic process GO:0009150 290 0.125
regulation of transferase activity GO:0051338 263 0.125
aromatic compound catabolic process GO:0019439 286 0.124
cellular amine metabolic process GO:0044106 44 0.123
nitrogen compound transport GO:0071705 271 0.122
regulation of blood circulation GO:1903522 93 0.120
Mouse
cellular lipid metabolic process GO:0044255 323 0.119
response to nutrient levels GO:0031667 109 0.119
ribonucleotide metabolic process GO:0009259 291 0.116
divalent inorganic cation homeostasis GO:0072507 138 0.116
regulation of tube size GO:0035150 57 0.116
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.114
gonad development GO:0008406 141 0.113
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.110
cellular homeostasis GO:0019725 240 0.109
neural tube formation GO:0001841 108 0.108
small gtpase mediated signal transduction GO:0007264 97 0.107
gland development GO:0048732 330 0.106
renal system development GO:0072001 225 0.106
ameboidal type cell migration GO:0001667 128 0.105
positive regulation of transferase activity GO:0051347 167 0.105
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.105
morphogenesis of embryonic epithelium GO:0016331 159 0.104
regulation of neuron differentiation GO:0045664 281 0.102
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.102
nucleoside metabolic process GO:0009116 246 0.101
regulation of establishment of planar polarity GO:0090175 28 0.101
positive regulation of protein modification process GO:0031401 299 0.100
angiogenesis GO:0001525 201 0.100
positive regulation of protein phosphorylation GO:0001934 242 0.099
purine nucleoside catabolic process GO:0006152 205 0.099
positive regulation of hydrolase activity GO:0051345 148 0.097
neuron apoptotic process GO:0051402 142 0.097
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.094
neuron projection guidance GO:0097485 141 0.094
muscle tissue development GO:0060537 308 0.093
negative regulation of cellular protein metabolic process GO:0032269 247 0.093
cellular ion homeostasis GO:0006873 165 0.091
negative regulation of neuron projection development GO:0010977 50 0.091
glucose homeostasis GO:0042593 128 0.091
regulation of heart contraction GO:0008016 77 0.091
regulation of intracellular transport GO:0032386 159 0.089
ribonucleoside triphosphate metabolic process GO:0009199 220 0.089
regulation of cell adhesion GO:0030155 154 0.089
positive regulation of cellular amine metabolic process GO:0033240 5 0.088
epithelial tube formation GO:0072175 130 0.087
negative regulation of molecular function GO:0044092 258 0.087
ion transmembrane transport GO:0034220 361 0.086
purine ribonucleotide catabolic process GO:0009154 208 0.086
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.086
hormone secretion GO:0046879 128 0.085
spermatogenesis GO:0007283 284 0.084
neuron death GO:0070997 154 0.083
ribose phosphate metabolic process GO:0019693 291 0.083
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.082
purine containing compound catabolic process GO:0072523 213 0.082
morphogenesis of a branching epithelium GO:0061138 193 0.081
g protein coupled receptor signaling pathway GO:0007186 243 0.081
negative regulation of phosphorus metabolic process GO:0010563 184 0.080
regulation of neural precursor cell proliferation GO:2000177 70 0.080
positive regulation of mapk cascade GO:0043410 170 0.080
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.079
embryonic skeletal system development GO:0048706 120 0.079
regulation of cytoskeleton organization GO:0051493 122 0.078
organic hydroxy compound transport GO:0015850 93 0.078
regulation of cell migration GO:0030334 219 0.078
Human
limb morphogenesis GO:0035108 149 0.078
regulation of hormone levels GO:0010817 211 0.077
nucleoside catabolic process GO:0009164 206 0.077
axon guidance GO:0007411 141 0.075
purine ribonucleoside metabolic process GO:0046128 241 0.075
regulation of nucleotide metabolic process GO:0006140 169 0.075
organic cyclic compound catabolic process GO:1901361 295 0.075
lymphocyte differentiation GO:0030098 242 0.075
response to radiation GO:0009314 165 0.075
regulation of hormone secretion GO:0046883 88 0.074
tube closure GO:0060606 91 0.074
nucleoside triphosphate metabolic process GO:0009141 230 0.073
kidney epithelium development GO:0072073 121 0.073
regulation of lymphocyte activation GO:0051249 240 0.073
cell adhesion GO:0007155 329 0.073
peptide secretion GO:0002790 114 0.073
insulin secretion GO:0030073 89 0.072
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
neural crest cell differentiation GO:0014033 54 0.072
purine nucleoside triphosphate catabolic process GO:0009146 203 0.072
bone development GO:0060348 120 0.070
glycosyl compound catabolic process GO:1901658 206 0.070
nucleobase containing small molecule metabolic process GO:0055086 352 0.070
organic anion transport GO:0015711 137 0.069
purine nucleoside metabolic process GO:0042278 241 0.069
wound healing GO:0042060 157 0.069
sympathetic neuron projection extension GO:0097490 4 0.068
regulation of kinase activity GO:0043549 249 0.068
ribonucleoside catabolic process GO:0042454 206 0.067
acetylcholine transport GO:0015870 2 0.067
morphogenesis of a polarized epithelium GO:0001738 37 0.067
negative regulation of cell proliferation GO:0008285 296 0.067
Human
non canonical wnt signaling pathway GO:0035567 33 0.067
regulation of ossification GO:0030278 112 0.066
glycosyl compound metabolic process GO:1901657 246 0.066
sensory perception GO:0007600 245 0.065
heterocycle catabolic process GO:0046700 280 0.065
stem cell proliferation GO:0072089 117 0.065
synapse organization GO:0050808 125 0.065
Mouse
regulation of protein kinase activity GO:0045859 232 0.065
nucleotide catabolic process GO:0009166 217 0.065
regulation of rho gtpase activity GO:0032319 58 0.064
regulation of peptide transport GO:0090087 91 0.064
mesoderm development GO:0007498 100 0.064
organ growth GO:0035265 117 0.064
carbohydrate derivative catabolic process GO:1901136 231 0.064
embryonic digit morphogenesis GO:0042733 56 0.064
stem cell differentiation GO:0048863 268 0.063
tube formation GO:0035148 140 0.063
response to extracellular stimulus GO:0009991 127 0.063
positive regulation of secretion by cell GO:1903532 114 0.063
neurotransmitter secretion GO:0007269 62 0.062
regulation of body fluid levels GO:0050878 162 0.062
t cell differentiation GO:0030217 174 0.062
ossification GO:0001503 216 0.062
stem cell development GO:0048864 219 0.061
cellular chemical homeostasis GO:0055082 215 0.061
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.061
trunk neural crest cell migration GO:0036484 4 0.061
purine ribonucleoside catabolic process GO:0046130 205 0.061
nephron tubule development GO:0072080 84 0.061
regulation of reproductive process GO:2000241 66 0.061
negative regulation of cellular amine metabolic process GO:0033239 1 0.061
cellular response to organonitrogen compound GO:0071417 145 0.060
purine nucleoside triphosphate metabolic process GO:0009144 226 0.060
central nervous system neuron development GO:0021954 67 0.060
cellular protein complex assembly GO:0043623 116 0.060
spinal cord development GO:0021510 81 0.060
Mouse
organophosphate catabolic process GO:0046434 232 0.060
protein catabolic process GO:0030163 221 0.059
intracellular protein transport GO:0006886 204 0.059
neural tube development GO:0021915 160 0.059
regulation of nucleotide catabolic process GO:0030811 122 0.059
metal ion homeostasis GO:0055065 189 0.059
establishment of planar polarity GO:0001736 28 0.058
mesenchyme development GO:0060485 152 0.057
regulation of neuron death GO:1901214 134 0.057
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.057
peptidyl amino acid modification GO:0018193 336 0.056
regulation of secretion GO:0051046 274 0.056
development of primary sexual characteristics GO:0045137 143 0.056
regulation of protein serine threonine kinase activity GO:0071900 157 0.056
carbohydrate homeostasis GO:0033500 128 0.056
cytoplasmic transport GO:0016482 234 0.056
positive regulation of cell development GO:0010720 237 0.056
Mouse
midgut development GO:0007494 4 0.055
acetylcholine secretion neurotransmission GO:0014055 2 0.055
trunk segmentation GO:0035290 4 0.055
cellular response to hormone stimulus GO:0032870 150 0.054
visual behavior GO:0007632 45 0.054
negative regulation of hydrolase activity GO:0051346 71 0.054
developmental cell growth GO:0048588 84 0.054
nucleoside triphosphate catabolic process GO:0009143 205 0.054
ureteric bud development GO:0001657 94 0.053
response to organonitrogen compound GO:0010243 246 0.053
placenta development GO:0001890 140 0.053
regulation of cell projection organization GO:0031344 206 0.053
Mouse
gtp catabolic process GO:0006184 143 0.052
positive regulation of rho gtpase activity GO:0032321 41 0.052
positive regulation of nucleoside metabolic process GO:0045979 91 0.052
transmembrane transport GO:0055085 412 0.052
ribonucleoside metabolic process GO:0009119 245 0.051
cation transport GO:0006812 399 0.051
leukocyte differentiation GO:0002521 342 0.050
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.050
cellular nitrogen compound catabolic process GO:0044270 280 0.050
male gamete generation GO:0048232 285 0.050
amide transport GO:0042886 138 0.050
muscular septum morphogenesis GO:0003150 4 0.050
organelle localization GO:0051640 179 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.049
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.049
Mouse
cardiac chamber development GO:0003205 108 0.049
cell fate commitment GO:0045165 210 0.048
lipid transport GO:0006869 98 0.048
nephron morphogenesis GO:0072028 69 0.047
cell growth GO:0016049 130 0.047
neuroblast proliferation GO:0007405 49 0.047
regulation of establishment of protein localization GO:0070201 181 0.047
cellular response to peptide GO:1901653 92 0.047
cardiac septum development GO:0003279 59 0.046
purine containing compound metabolic process GO:0072521 311 0.046
negative regulation of protein modification process GO:0031400 163 0.046
mesonephros development GO:0001823 97 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.046
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.046
positive regulation of nucleotide catabolic process GO:0030813 88 0.046
lung development GO:0030324 164 0.046
regulation of system process GO:0044057 200 0.046
Mouse
positive regulation of proteolysis GO:0045862 85 0.046
metencephalon development GO:0022037 89 0.046
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.046
mesonephric tubule development GO:0072164 94 0.046
apoptotic signaling pathway GO:0097190 306 0.046
negative regulation of neuron death GO:1901215 98 0.045
female gonad development GO:0008585 71 0.045
epithelial cell development GO:0002064 159 0.045
limb development GO:0060173 166 0.045
dendrite development GO:0016358 115 0.045
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.045
developmental growth involved in morphogenesis GO:0060560 138 0.045
monocarboxylic acid metabolic process GO:0032787 191 0.045
positive regulation of stem cell proliferation GO:2000648 59 0.044
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.044
negative regulation of neuron apoptotic process GO:0043524 92 0.044
positive regulation of protein kinase activity GO:0045860 144 0.044
positive regulation of cellular component biogenesis GO:0044089 94 0.044
regulation of chemotaxis GO:0050920 53 0.043
regulation of organelle organization GO:0033043 289 0.043
cytokine production GO:0001816 319 0.043
positive regulation of kinase activity GO:0033674 155 0.043
multi multicellular organism process GO:0044706 109 0.043
negative regulation of intracellular signal transduction GO:1902532 167 0.043
cellular metal ion homeostasis GO:0006875 151 0.043
nucleoside phosphate catabolic process GO:1901292 222 0.043
canonical wnt signaling pathway GO:0060070 130 0.043
Human
development of primary female sexual characteristics GO:0046545 73 0.043
skeletal muscle organ development GO:0060538 163 0.043
regulation of circadian sleep wake cycle GO:0042749 3 0.042
regulation of purine nucleotide catabolic process GO:0033121 122 0.042
cytosolic calcium ion homeostasis GO:0051480 70 0.042
cardiac ventricle development GO:0003231 83 0.042
nucleotide metabolic process GO:0009117 332 0.042
circulatory system process GO:0003013 197 0.042
Mouse
hormone metabolic process GO:0042445 86 0.041
regulation of protein localization GO:0032880 231 0.041
negative regulation of protein metabolic process GO:0051248 282 0.041
peptide transport GO:0015833 133 0.041
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.040
sympathetic neuron projection guidance GO:0097491 4 0.040
positive regulation of nucleotide metabolic process GO:0045981 114 0.040
response to light stimulus GO:0009416 135 0.040
somite development GO:0061053 81 0.040
autonomic nervous system development GO:0048483 43 0.039
regulation of purine nucleotide metabolic process GO:1900542 169 0.039
endomembrane system organization GO:0010256 147 0.039
sensory perception of mechanical stimulus GO:0050954 107 0.039
cellular carbohydrate metabolic process GO:0044262 119 0.039
cardiac muscle cell differentiation GO:0055007 69 0.038
regulation of secretion by cell GO:1903530 249 0.038
respiratory system development GO:0060541 190 0.038
regulation of epithelial cell migration GO:0010632 35 0.038
ear development GO:0043583 200 0.038
negative regulation of neuron differentiation GO:0045665 101 0.038
ventral spinal cord development GO:0021517 48 0.038
aminoglycan metabolic process GO:0006022 34 0.038
negative regulation of cell motility GO:2000146 61 0.038
Human
female sex differentiation GO:0046660 84 0.037
actin filament organization GO:0007015 113 0.037
muscle system process GO:0003012 141 0.037
t cell differentiation in thymus GO:0033077 77 0.037
guanosine containing compound catabolic process GO:1901069 144 0.037
microtubule based process GO:0007017 236 0.037
determination of left right symmetry GO:0007368 80 0.037
rhythmic process GO:0048511 174 0.037
ribonucleotide catabolic process GO:0009261 208 0.037
germ cell development GO:0007281 185 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
regulation of cell substrate adhesion GO:0010810 73 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.036
cellular response to oxidative stress GO:0034599 76 0.036
calcium ion transport GO:0006816 159 0.036
divalent inorganic cation transport GO:0072511 178 0.036
multicellular organismal signaling GO:0035637 91 0.035
sensory perception of sound GO:0007605 97 0.035
regulation of angiogenesis GO:0045765 81 0.035
nephron epithelium development GO:0072009 92 0.035
negative regulation of catenin import into nucleus GO:0035414 2 0.035
blood vessel morphogenesis GO:0048514 285 0.035
regulation of mapk cascade GO:0043408 248 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
protein ubiquitination GO:0016567 171 0.035
regulation of actin filament based process GO:0032970 99 0.035
forebrain neuron development GO:0021884 30 0.035
establishment of protein localization to organelle GO:0072594 118 0.035
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.034
dichotomous subdivision of an epithelial terminal unit GO:0060600 11 0.034
regulation of chorionic trophoblast cell proliferation GO:1901382 1 0.034
blood coagulation GO:0007596 76 0.034
positive regulation of ras gtpase activity GO:0032320 65 0.034
ureteric bud morphogenesis GO:0060675 62 0.034
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.034
regulation of t cell activation GO:0050863 170 0.034
cellular response to peptide hormone stimulus GO:0071375 92 0.034
retinal blood vessel morphogenesis GO:0061304 3 0.034
regulation of cell size GO:0008361 72 0.034
heart contraction GO:0060047 93 0.033
maintenance of cell number GO:0098727 3 0.033
oxidation reduction process GO:0055114 342 0.033
endodermal cell fate specification GO:0001714 4 0.033
regulation of binding GO:0051098 111 0.033
response to peptide hormone GO:0043434 127 0.033
regulation of blood pressure GO:0008217 93 0.033
kidney morphogenesis GO:0060993 83 0.033
cellular response to cytokine stimulus GO:0071345 189 0.033
diencephalon development GO:0021536 63 0.033
steroid metabolic process GO:0008202 119 0.033
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.032
epidermis development GO:0008544 187 0.032
embryonic limb morphogenesis GO:0030326 126 0.032
regulation of heart rate GO:0002027 36 0.032
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.032
heart morphogenesis GO:0003007 178 0.032
neuron neuron synaptic transmission GO:0007270 69 0.032
regulation of apoptotic signaling pathway GO:2001233 197 0.031
leukocyte apoptotic process GO:0071887 71 0.031
protein localization to nucleus GO:0034504 121 0.031
modification dependent macromolecule catabolic process GO:0043632 133 0.031
cell maturation GO:0048469 127 0.031
positive regulation of cell activation GO:0050867 158 0.031
neural precursor cell proliferation GO:0061351 121 0.031
protein autophosphorylation GO:0046777 61 0.031
leukocyte migration GO:0050900 124 0.031
regulation of ras gtpase activity GO:0032318 88 0.031
synapse assembly GO:0007416 56 0.031
Mouse
telencephalon development GO:0021537 186 0.031
Mouse
b cell activation GO:0042113 161 0.030
kidney development GO:0001822 213 0.030
neural crest cell migration GO:0001755 32 0.030
neural crest cell development GO:0014032 48 0.030
positive regulation of secretion GO:0051047 130 0.030
tissue remodeling GO:0048771 102 0.030
negative regulation of cell projection organization GO:0031345 56 0.030
visual learning GO:0008542 44 0.030
protein targeting GO:0006605 143 0.030
regulation of membrane potential GO:0042391 192 0.030
cellular response to growth factor stimulus GO:0071363 197 0.030
regulation of mitotic cell cycle GO:0007346 126 0.030
digestive tract development GO:0048565 190 0.030
negative regulation of synapse assembly GO:0051964 3 0.030
cranial nerve development GO:0021545 41 0.029
regulation of ion transport GO:0043269 215 0.029
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.029
response to starvation GO:0042594 65 0.029
mitochondrion organization GO:0007005 134 0.029
response to organic cyclic compound GO:0014070 198 0.029
cardiac muscle tissue development GO:0048738 130 0.029
branching involved in ureteric bud morphogenesis GO:0001658 56 0.029
neuron projection extension GO:1990138 64 0.029
membrane organization GO:0061024 245 0.029
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.029
regulation of tight junction assembly GO:2000810 2 0.029
mapk cascade GO:0000165 281 0.029
social behavior GO:0035176 21 0.028
branchiomotor neuron axon guidance GO:0021785 7 0.028
peptidyl serine modification GO:0018209 83 0.028
cell differentiation in hindbrain GO:0021533 24 0.028
syncytium formation by plasma membrane fusion GO:0000768 42 0.028
muscle cell development GO:0055001 133 0.028
carbohydrate derivative biosynthetic process GO:1901137 183 0.028
eye photoreceptor cell differentiation GO:0001754 41 0.028
negative regulation of hepatocyte differentiation GO:0070367 1 0.028
positive regulation of nervous system development GO:0051962 221 0.028
Mouse
outflow tract morphogenesis GO:0003151 53 0.028
respiratory tube development GO:0030323 167 0.028
muscle fiber development GO:0048747 76 0.027
anion transport GO:0006820 177 0.027
development of primary male sexual characteristics GO:0046546 88 0.027
retina vasculature development in camera type eye GO:0061298 17 0.027
negative regulation of cellular component organization GO:0051129 194 0.027
response to growth factor GO:0070848 198 0.027
regulation of rho protein signal transduction GO:0035023 71 0.027
fatty acid metabolic process GO:0006631 121 0.027
response to insulin GO:0032868 100 0.027
regulation of cytoplasmic transport GO:1903649 112 0.027
positive regulation of cell motility GO:2000147 116 0.027
central nervous system neuron axonogenesis GO:0021955 28 0.027
regulation of stem cell proliferation GO:0072091 78 0.027
mesonephric tubule morphogenesis GO:0072171 63 0.026
leukocyte proliferation GO:0070661 172 0.026
cardiac chamber morphogenesis GO:0003206 93 0.026
regulation of proteolysis GO:0030162 164 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
regulation of lipid metabolic process GO:0019216 118 0.026
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.026
epithelial cell migration GO:0010631 63 0.026
positive regulation of gtpase activity GO:0043547 85 0.026
endothelial cell migration GO:0043542 44 0.026
hepaticobiliary system development GO:0061008 67 0.026
regulation of ras protein signal transduction GO:0046578 114 0.025
peptidyl tyrosine modification GO:0018212 145 0.025
spermatid differentiation GO:0048515 115 0.025
negative regulation of bmp signaling pathway GO:0030514 35 0.025
sequestering of calcium ion GO:0051208 18 0.025
sensory organ morphogenesis GO:0090596 242 0.025
anatomical structure maturation GO:0071695 49 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.025
regulation of cell cycle GO:0051726 281 0.025
establishment or maintenance of cell polarity GO:0007163 86 0.025
positive regulation of gtp catabolic process GO:0033126 85 0.025
engulfment of apoptotic cell GO:0043652 3 0.025
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.025
transmission of nerve impulse GO:0019226 76 0.025
regulation of extent of cell growth GO:0061387 52 0.025
embryonic skeletal system morphogenesis GO:0048704 91 0.025
ovulation cycle GO:0042698 59 0.024
calcium ion homeostasis GO:0055074 127 0.024
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.024
Mouse
actin cytoskeleton organization GO:0030036 220 0.024
positive regulation of protein secretion GO:0050714 52 0.024
ganglion development GO:0061548 13 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
sequestering of metal ion GO:0051238 19 0.024
plasma membrane organization GO:0007009 90 0.024
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.024
heart process GO:0003015 94 0.024
response to camp GO:0051591 14 0.024
regulation of epithelial cell proliferation GO:0050678 141 0.024
chorionic trophoblast cell proliferation GO:0097360 1 0.024
peptide hormone secretion GO:0030072 109 0.024
developmental programmed cell death GO:0010623 41 0.024
regulation of cell growth GO:0001558 91 0.024
trabecula morphogenesis GO:0061383 40 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.023
mesodermal cell migration GO:0008078 4 0.023
gtp metabolic process GO:0046039 144 0.023
response to alcohol GO:0097305 48 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
response to monosaccharide GO:0034284 67 0.023
lipid biosynthetic process GO:0008610 179 0.023
forebrain generation of neurons GO:0021872 63 0.023
endocrine process GO:0050886 39 0.023
establishment of tissue polarity GO:0007164 28 0.023
nephron epithelium morphogenesis GO:0072088 68 0.023
regulation of engulfment of apoptotic cell GO:1901074 2 0.023
sulfur compound metabolic process GO:0006790 100 0.023
multi organism behavior GO:0051705 62 0.023
syncytiotrophoblast cell differentiation involved in labyrinthine layer development GO:0060715 2 0.023
neurotransmitter transport GO:0006836 76 0.023
guanosine containing compound metabolic process GO:1901068 144 0.023
positive regulation of smooth muscle cell migration GO:0014911 4 0.023

Ptpru disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.117
nervous system disease DOID:863 0 0.117
central nervous system disease DOID:331 0 0.036