|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.425
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.415
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.342
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.305
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.300
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.256
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.252
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.250
|
Fly |
|
|
t cell activation
|
GO:0042110 |
289 |
0.242
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.234
|
Mouse |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.229
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.222
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.194
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.188
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.182
|
Mouse |
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.181
|
Worm |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.180
|
Zebrafish Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.180
|
Fly |
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.175
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.171
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.169
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.169
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.166
|
Zebrafish |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.159
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.159
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.157
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.155
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.153
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.150
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.149
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.144
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.138
|
Mouse |
|
|
cognition
|
GO:0050890 |
149 |
0.138
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.134
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.132
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.131
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.127
|
Mouse |
|
|
positive regulation of podosome assembly
|
GO:0071803 |
3 |
0.126
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.125
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.124
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.120
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.120
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.117
|
Mouse |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.116
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.116
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.116
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.114
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.112
|
Worm |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.109
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.107
|
Mouse |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.107
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.107
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.106
|
Zebrafish |
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.106
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.104
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.103
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.102
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.102
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.101
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.098
|
|
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
3 |
0.098
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.096
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.096
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.096
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.095
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.094
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.094
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.093
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.093
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.092
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.091
|
Mouse |
|
|
cell junction organization
|
GO:0034330 |
77 |
0.091
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.089
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.089
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.088
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.088
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.088
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.086
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.085
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.085
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.085
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.085
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.084
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.084
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.083
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.083
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
14 |
0.083
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.082
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.082
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.081
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.081
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.080
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.080
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.079
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.078
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.078
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.077
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.076
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.076
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.075
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.075
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.073
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.073
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.073
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.072
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.072
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.072
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.070
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.069
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.069
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.068
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.067
|
Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.067
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.066
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.065
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.065
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.064
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.064
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.063
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.062
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.062
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.062
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.061
|
Mouse |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.061
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.061
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.061
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.060
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.060
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.060
|
|
|
|
response to fibroblast growth factor
|
GO:0071774 |
47 |
0.059
|
Worm |
|
|
gland development
|
GO:0048732 |
330 |
0.059
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.059
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.059
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.058
|
Mouse |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.058
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.057
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.057
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.056
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.056
|
Mouse |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.056
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.056
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.056
|
Mouse |
|
|
immune response inhibiting signal transduction
|
GO:0002765 |
4 |
0.056
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.055
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.054
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.054
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.054
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.054
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.053
|
Mouse |
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
6 |
0.053
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.053
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.053
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.052
|
Mouse |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.051
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.051
|
Mouse |
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.051
|
Mouse |
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
13 |
0.050
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.050
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.050
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.050
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.049
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.049
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.049
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.048
|
Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.048
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.048
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.047
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.047
|
Zebrafish Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.047
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
34 |
0.047
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.046
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.046
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.046
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.046
|
Mouse |
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.046
|
Fly |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.046
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.045
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.045
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.045
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.045
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.045
|
Zebrafish Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.045
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.045
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.044
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.044
|
Mouse |
|
|
regulation of podosome assembly
|
GO:0071801 |
3 |
0.044
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.044
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.044
|
Mouse |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.042
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.042
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.042
|
Mouse |
|
|
endoderm development
|
GO:0007492 |
45 |
0.042
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.042
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.042
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.041
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.041
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.041
|
Fly |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.041
|
Zebrafish |
|
|
protein secretion
|
GO:0009306 |
111 |
0.040
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.040
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.040
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.040
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.040
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.039
|
Mouse |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.039
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.039
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.039
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.039
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.039
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.039
|
Mouse |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.039
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.039
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.038
|
Mouse |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.038
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.038
|
Mouse |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.038
|
Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.038
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.038
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.037
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.037
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.037
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.037
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.037
|
Mouse |
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.036
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.036
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.036
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.036
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.035
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.035
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.035
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.035
|
Worm |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.035
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.035
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.035
|
|
|
|
exploration behavior
|
GO:0035640 |
21 |
0.034
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.034
|
|
|
|
memory
|
GO:0007613 |
58 |
0.034
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.034
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.034
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.034
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.033
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.033
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.033
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.033
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.033
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.033
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.033
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.033
|
|
|
|
positive regulation of dendritic cell apoptotic process
|
GO:2000670 |
3 |
0.032
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.032
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.032
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.032
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.032
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.031
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.031
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.031
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.031
|
Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.031
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.031
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.031
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.031
|
Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.031
|
Mouse |
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.031
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.031
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.031
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
16 |
0.030
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.030
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.030
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.030
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.030
|
Mouse |
|
|
response to organophosphorus
|
GO:0046683 |
22 |
0.030
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.030
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.030
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.030
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.030
|
Mouse |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.029
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.029
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.029
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.029
|
Mouse |
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.028
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.028
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.028
|
Mouse |
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.028
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.028
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.028
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.027
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.027
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.027
|
Rat |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.027
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.027
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.027
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.027
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.027
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.027
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.027
|
Mouse |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.026
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.026
|
Mouse |
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.026
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.026
|
Mouse |
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.026
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.026
|
Mouse |
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.026
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.025
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.025
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.025
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.025
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.025
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.025
|
Fly |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.025
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.025
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.025
|
Mouse |
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.025
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.025
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.025
|
Rat |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.025
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.025
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.025
|
Zebrafish |
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.025
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.025
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.025
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.024
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.024
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.024
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.024
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.024
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.024
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.024
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.024
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.023
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.023
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.023
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
7 |
0.023
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.023
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.023
|
Mouse |
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.023
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.023
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.023
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.023
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.023
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.023
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.023
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.023
|
Mouse |
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.023
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.023
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.023
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.023
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.023
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.023
|
Mouse |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.023
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.023
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.022
|
Mouse |
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.022
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.022
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.022
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.022
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.022
|
|
|
|
toll like receptor 4 signaling pathway
|
GO:0034142 |
9 |
0.022
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.022
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.022
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.022
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.022
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.022
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.022
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.022
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.022
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.022
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.022
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.022
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.021
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.021
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.021
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.021
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.021
|
|
|
|
lipoprotein metabolic process
|
GO:0042157 |
43 |
0.021
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.021
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.021
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.021
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.021
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.021
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.021
|
|
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.021
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.021
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.021
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.021
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.021
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.021
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.020
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
19 |
0.020
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.020
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.020
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.020
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.020
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.020
|
|
|
|
cell cell junction assembly
|
GO:0007043 |
27 |
0.020
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.020
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.020
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.020
|
|
|
|
activation of rac gtpase activity
|
GO:0032863 |
2 |
0.020
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.020
|
Mouse |
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
2 |
0.020
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.020
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.020
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.019
|
Mouse |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.019
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.019
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.019
|
Mouse |
|
|
exocrine system development
|
GO:0035272 |
45 |
0.019
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.019
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
57 |
0.019
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.019
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.019
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.019
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.019
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.019
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.019
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.019
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.019
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.019
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.018
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.018
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.018
|
|
|
|
negative regulation of erbb signaling pathway
|
GO:1901185 |
7 |
0.018
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.018
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.018
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.018
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.018
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.018
|
Mouse |
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.018
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.018
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.018
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.018
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.018
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.018
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.018
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.017
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.017
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.017
|
Mouse |
|
|
cell growth
|
GO:0016049 |
130 |
0.017
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.017
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.017
|
Mouse |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.017
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.017
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.017
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.017
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.017
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.017
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.017
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.017
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.017
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.017
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.017
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.017
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.017
|
Mouse |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.017
|
|
|
|
response to camp
|
GO:0051591 |
14 |
0.017
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.017
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.017
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.017
|
Zebrafish |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.017
|
|
|
|
filtration diaphragm assembly
|
GO:0036058 |
1 |
0.017
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.016
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.016
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.016
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.016
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.016
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.016
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.016
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.016
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.016
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.016
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.016
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.016
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.016
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.016
|
Rat |
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
8 |
0.016
|
Mouse |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.016
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.016
|
|
|
|
positive regulation of apoptotic cell clearance
|
GO:2000427 |
3 |
0.016
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.016
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.016
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.016
|
Mouse |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.016
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.016
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.016
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.016
|
Mouse |
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.016
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.015
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.015
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.015
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.015
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.015
|
Mouse |
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.015
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.015
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.015
|
|
