Mus musculus

15 known processes

Pde6a

phosphodiesterase 6A, cGMP-specific, rod, alpha

(Aliases: MGC25111,Pdea,nmf282)

Pde6a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.821
regulation of membrane potential GO:0042391 192 0.507
organic hydroxy compound transport GO:0015850 93 0.494
cellular amino acid metabolic process GO:0006520 103 0.489
transmembrane transport GO:0055085 412 0.456
cation transport GO:0006812 399 0.443
synaptic transmission GO:0007268 329 0.397
cation transmembrane transport GO:0098655 266 0.394
amine metabolic process GO:0009308 45 0.379
visual perception GO:0007601 52 0.337
Mouse
cellular ketone metabolic process GO:0042180 84 0.326
multicellular organismal signaling GO:0035637 91 0.315
regulation of cellular amine metabolic process GO:0033238 20 0.304
rhodopsin mediated signaling pathway GO:0016056 4 0.293
negative regulation of phosphate metabolic process GO:0045936 184 0.271
Mouse
response to light stimulus GO:0009416 135 0.271
Mouse
regulation of feeding behavior GO:0060259 3 0.256
inorganic ion transmembrane transport GO:0098660 234 0.254
sodium ion transport GO:0006814 73 0.229
brown fat cell differentiation GO:0050873 36 0.226
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.219
sensitization GO:0046960 2 0.211
gastrin induced gastric acid secretion GO:0001698 1 0.211
inorganic cation transmembrane transport GO:0098662 207 0.209
cellular nitrogen compound catabolic process GO:0044270 280 0.201
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.200
histamine induced gastric acid secretion GO:0001697 1 0.193
regulation of cellular amino acid metabolic process GO:0006521 5 0.193
purine nucleotide metabolic process GO:0006163 302 0.186
Mouse
cellular amine metabolic process GO:0044106 44 0.183
conditioned taste aversion GO:0001661 4 0.180
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.173
g protein coupled receptor internalization GO:0002031 3 0.172
regulation of cellular ketone metabolic process GO:0010565 66 0.169
response to organonitrogen compound GO:0010243 246 0.166
phototransduction GO:0007602 17 0.155
Mouse
regulation of transferase activity GO:0051338 263 0.153
regulation of secretion GO:0051046 274 0.152
regulation of kinase activity GO:0043549 249 0.151
negative regulation of nucleotide metabolic process GO:0045980 16 0.149
Mouse
divalent metal ion transport GO:0070838 172 0.144
neuron neuron synaptic transmission GO:0007270 69 0.143
acid secretion GO:0046717 33 0.138
positive regulation of cellular amine metabolic process GO:0033240 5 0.138
nitrogen compound transport GO:0071705 271 0.135
fat cell differentiation GO:0045444 160 0.129
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.127
oxidation reduction process GO:0055114 342 0.125
sensory perception GO:0007600 245 0.124
Mouse
anion transport GO:0006820 177 0.123
erk1 and erk2 cascade GO:0070371 77 0.122
anion transmembrane transport GO:0098656 71 0.121
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.119
lipid transport GO:0006869 98 0.118
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.111
regulation of hormone levels GO:0010817 211 0.108
heterocycle catabolic process GO:0046700 280 0.108
Mouse
visual behavior GO:0007632 45 0.106
organic acid transport GO:0015849 101 0.105
amide transport GO:0042886 138 0.104
ribose phosphate metabolic process GO:0019693 291 0.104
Mouse
digestive tract development GO:0048565 190 0.101
potassium ion transport GO:0006813 52 0.099
response to radiation GO:0009314 165 0.099
Mouse
nucleotide metabolic process GO:0009117 332 0.096
Mouse
glucose transport GO:0015758 56 0.095
multicellular organismal response to stress GO:0033555 62 0.093
anatomical structure homeostasis GO:0060249 145 0.093
nucleobase containing small molecule metabolic process GO:0055086 352 0.093
Mouse
regulation of body fluid levels GO:0050878 162 0.091
mapk cascade GO:0000165 281 0.090
lipid localization GO:0010876 126 0.089
muscle tissue development GO:0060537 308 0.089
carboxylic acid transport GO:0046942 100 0.089
synaptic transmission glutamatergic GO:0035249 36 0.087
neurotransmitter transport GO:0006836 76 0.086
carbohydrate transport GO:0008643 62 0.085
divalent inorganic cation homeostasis GO:0072507 138 0.085
adult behavior GO:0030534 135 0.084
monosaccharide transport GO:0015749 58 0.084
cellular response to temperature stimulus GO:0071502 2 0.084
nucleoside metabolic process GO:0009116 246 0.083
positive regulation of protein modification process GO:0031401 299 0.082
detection of light stimulus GO:0009583 25 0.082
Mouse
hexose transport GO:0008645 56 0.082
metal ion homeostasis GO:0055065 189 0.081
regulation of protein serine threonine kinase activity GO:0071900 157 0.081
adult walking behavior GO:0007628 41 0.081
camera type eye development GO:0043010 266 0.081
purine containing compound catabolic process GO:0072523 213 0.080
Mouse
action potential GO:0001508 78 0.079
organic cyclic compound catabolic process GO:1901361 295 0.079
Mouse
inorganic anion transmembrane transport GO:0098661 29 0.078
learning or memory GO:0007611 148 0.078
central nervous system neuron differentiation GO:0021953 162 0.077
peptidyl tyrosine modification GO:0018212 145 0.076
purine containing compound metabolic process GO:0072521 311 0.076
Mouse
muscle contraction GO:0006936 101 0.075
renal system process GO:0003014 48 0.074
sensory perception of pain GO:0019233 47 0.074
nucleoside phosphate metabolic process GO:0006753 338 0.073
Mouse
visual learning GO:0008542 44 0.072
purine ribonucleoside metabolic process GO:0046128 241 0.071
peptide hormone secretion GO:0030072 109 0.071
regulation of circadian sleep wake cycle GO:0042749 3 0.070
positive regulation of secretion GO:0051047 130 0.069
associative learning GO:0008306 61 0.069
membrane organization GO:0061024 245 0.068
detection of abiotic stimulus GO:0009582 60 0.068
Mouse
multicellular organismal homeostasis GO:0048871 164 0.067
peptidyl amino acid modification GO:0018193 336 0.067
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.067
gland development GO:0048732 330 0.067
activation of adenylate cyclase activity GO:0007190 4 0.066
peptidyl tyrosine phosphorylation GO:0018108 143 0.066
sodium ion transmembrane transport GO:0035725 49 0.065
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.064
organic hydroxy compound metabolic process GO:1901615 203 0.064
response to organic cyclic compound GO:0014070 198 0.064
negative regulation of phosphorus metabolic process GO:0010563 184 0.064
Mouse
regulation of postsynaptic membrane potential GO:0060078 48 0.064
cytokine production GO:0001816 319 0.063
sensory perception of light stimulus GO:0050953 54 0.063
Mouse
organic anion transport GO:0015711 137 0.063
negative regulation of neuron death GO:1901215 98 0.062
digestive system development GO:0055123 200 0.061
carbohydrate derivative catabolic process GO:1901136 231 0.061
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.059
Mouse
glycosyl compound metabolic process GO:1901657 246 0.059
positive regulation of secretion by cell GO:1903532 114 0.059
maintenance of location GO:0051235 89 0.059
glial cell differentiation GO:0010001 131 0.059
purine nucleotide biosynthetic process GO:0006164 65 0.058
Mouse
fear response GO:0042596 33 0.058
long term synaptic potentiation GO:0060291 25 0.057
cellular homeostasis GO:0019725 240 0.057
response to extracellular stimulus GO:0009991 127 0.057
habituation GO:0046959 3 0.057
establishment of organelle localization GO:0051656 122 0.057
smooth muscle contraction GO:0006939 44 0.056
operant conditioning GO:0035106 2 0.056
positive regulation of protein phosphorylation GO:0001934 242 0.056
cytokine secretion GO:0050663 72 0.056
cellular response to organonitrogen compound GO:0071417 145 0.056
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.056
protein maturation GO:0051604 176 0.055
cellular divalent inorganic cation homeostasis GO:0072503 127 0.055
nucleoside catabolic process GO:0009164 206 0.055
positive regulation of transferase activity GO:0051347 167 0.055
digestion GO:0007586 40 0.054
purine ribonucleotide metabolic process GO:0009150 290 0.054
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.054
divalent inorganic cation transport GO:0072511 178 0.054
regulation of neurotransmitter levels GO:0001505 87 0.053
positive regulation of blood pressure GO:0045777 21 0.053
organelle localization GO:0051640 179 0.053
l amino acid transport GO:0015807 32 0.053
bone resorption GO:0045453 38 0.052
locomotory behavior GO:0007626 195 0.052
regulation of protein kinase activity GO:0045859 232 0.052
macromolecule catabolic process GO:0009057 281 0.052
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.052
Mouse
dopamine receptor signaling pathway GO:0007212 16 0.051
nucleoside triphosphate catabolic process GO:0009143 205 0.051
multicellular organism growth GO:0035264 161 0.051
nucleotide biosynthetic process GO:0009165 78 0.051
Mouse
ribonucleoside metabolic process GO:0009119 245 0.051
ribonucleoside triphosphate metabolic process GO:0009199 220 0.050
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.050
lipid biosynthetic process GO:0008610 179 0.050
nucleotide catabolic process GO:0009166 217 0.050
Mouse
peptide transport GO:0015833 133 0.050
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.049
apoptotic signaling pathway GO:0097190 306 0.049
response to drug GO:0042493 75 0.049
circulatory system process GO:0003013 197 0.049
memory GO:0007613 58 0.048
glycosyl compound catabolic process GO:1901658 206 0.048
axonogenesis GO:0007409 274 0.048
dopamine transport GO:0015872 15 0.048
purine nucleotide catabolic process GO:0006195 211 0.047
Mouse
cerebral cortex neuron differentiation GO:0021895 19 0.047
cellular response to growth factor stimulus GO:0071363 197 0.047
regulation of synaptic plasticity GO:0048167 87 0.047
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.047
regulation of hormone secretion GO:0046883 88 0.047
heart process GO:0003015 94 0.046
neuron death GO:0070997 154 0.046
calcium ion homeostasis GO:0055074 127 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.046
response to peptide hormone GO:0043434 127 0.045
membrane depolarization GO:0051899 64 0.045
positive regulation of mapk cascade GO:0043410 170 0.045
ribonucleoside catabolic process GO:0042454 206 0.045
regulation of fat cell differentiation GO:0045598 81 0.045
regulation of renal sodium excretion GO:0035813 3 0.045
peptide secretion GO:0002790 114 0.044
regulation of ion transport GO:0043269 215 0.044
response to histamine GO:0034776 1 0.044
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.044
nucleoside triphosphate metabolic process GO:0009141 230 0.044
purine containing compound biosynthetic process GO:0072522 70 0.044
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.044
Mouse
behavioral defense response GO:0002209 28 0.043
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.043
adult locomotory behavior GO:0008344 91 0.043
cellular potassium ion transport GO:0071804 43 0.042
negative regulation of cyclic nucleotide metabolic process GO:0030800 5 0.042
Mouse
sa node cell action potential GO:0086015 4 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
Mouse
phototransduction visible light GO:0007603 6 0.042
Mouse
positive regulation of glycolytic process GO:0045821 4 0.042
regulation of mapk cascade GO:0043408 248 0.042
response to amino acid GO:0043200 37 0.042
nucleoside phosphate catabolic process GO:1901292 222 0.041
Mouse
tissue homeostasis GO:0001894 115 0.041
regulation of lipid transport GO:0032368 36 0.041
extrinsic apoptotic signaling pathway GO:0097191 126 0.041
inorganic anion transport GO:0015698 43 0.041
cellular calcium ion homeostasis GO:0006874 119 0.041
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.041
neuron apoptotic process GO:0051402 142 0.040
calcium ion transport GO:0006816 159 0.040
cation homeostasis GO:0055080 212 0.039
organelle fission GO:0048285 170 0.039
positive regulation of kinase activity GO:0033674 155 0.039
regulation of peptide hormone secretion GO:0090276 75 0.039
regulation of neurotransmitter transport GO:0051588 35 0.038
retina development in camera type eye GO:0060041 119 0.038
cellular ion homeostasis GO:0006873 165 0.038
regulation of secretion by cell GO:1903530 249 0.038
renal sodium excretion GO:0035812 3 0.037
positive regulation of protein kinase activity GO:0045860 144 0.037
negative regulation of molecular function GO:0044092 258 0.037
heart contraction GO:0060047 93 0.037
hormone secretion GO:0046879 128 0.037
purine nucleoside catabolic process GO:0006152 205 0.037
camp biosynthetic process GO:0006171 31 0.036
Mouse
regulation of generation of precursor metabolites and energy GO:0043467 38 0.036
regulation of metal ion transport GO:0010959 106 0.036
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
regulation of hydrolase activity GO:0051336 246 0.036
phenol containing compound metabolic process GO:0018958 60 0.036
forebrain development GO:0030900 302 0.036
body fluid secretion GO:0007589 53 0.036
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.036
tissue remodeling GO:0048771 102 0.036
transmission of nerve impulse GO:0019226 76 0.035
endomembrane system organization GO:0010256 147 0.035
cellular lipid metabolic process GO:0044255 323 0.035
neuron migration GO:0001764 122 0.035
negative regulation of sterol transport GO:0032372 4 0.035
hormone metabolic process GO:0042445 86 0.034
sensory organ morphogenesis GO:0090596 242 0.034
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.034
retinal cone cell development GO:0046549 8 0.034
Mouse
glucose metabolic process GO:0006006 92 0.034
catecholamine secretion GO:0050432 15 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.033
membrane hyperpolarization GO:0060081 21 0.033
substrate independent telencephalic tangential migration GO:0021826 8 0.033
regulation of synaptic transmission glutamatergic GO:0051966 19 0.033
second messenger mediated signaling GO:0019932 73 0.032
Mouse
regulation of heart contraction GO:0008016 77 0.032
protein catabolic process GO:0030163 221 0.032
amino acid transport GO:0006865 61 0.032
protein modification by small protein conjugation or removal GO:0070647 207 0.032
feeding behavior GO:0007631 62 0.032
hexose metabolic process GO:0019318 98 0.031
potassium ion homeostasis GO:0055075 4 0.031
purine nucleoside triphosphate catabolic process GO:0009146 203 0.031
germ cell development GO:0007281 185 0.031
response to cocaine GO:0042220 14 0.031
nucleoside phosphate biosynthetic process GO:1901293 79 0.031
Mouse
muscle system process GO:0003012 141 0.030
central nervous system neuron development GO:0021954 67 0.030
purine ribonucleotide biosynthetic process GO:0009152 59 0.030
Mouse
negative regulation of cell proliferation GO:0008285 296 0.030
establishment of vesicle localization GO:0051650 81 0.030
negative regulation of muscle contraction GO:0045932 12 0.030
catecholamine metabolic process GO:0006584 30 0.030
behavioral response to cocaine GO:0048148 10 0.030
regulation of cell activation GO:0050865 289 0.029
protein import into nucleus GO:0006606 95 0.029
positive regulation of renal sodium excretion GO:0035815 2 0.029
organophosphate catabolic process GO:0046434 232 0.029
Mouse
regulation of organelle organization GO:0033043 289 0.029
cellular response to hormone stimulus GO:0032870 150 0.028
regulation of t cell activation GO:0050863 170 0.028
cognition GO:0050890 149 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
regulation of camp biosynthetic process GO:0030817 25 0.028
Mouse
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.028
steroid metabolic process GO:0008202 119 0.028
cytosolic calcium ion homeostasis GO:0051480 70 0.028
photoreceptor cell development GO:0042461 40 0.028
Mouse
potassium ion transmembrane transport GO:0071805 43 0.028
negative regulation of mapk cascade GO:0043409 65 0.028
aromatic compound catabolic process GO:0019439 286 0.027
Mouse
regulation of establishment of protein localization GO:0070201 181 0.027
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.027
circadian regulation of gene expression GO:0032922 48 0.027
response to insulin GO:0032868 100 0.027
gastric acid secretion GO:0001696 6 0.027
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.027
cardiac muscle hypertrophy GO:0003300 23 0.027
striated muscle hypertrophy GO:0014897 24 0.027
response to acid chemical GO:0001101 111 0.027
chloride transmembrane transport GO:1902476 24 0.027
cellular response to insulin stimulus GO:0032869 78 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
negative regulation of blood pressure GO:0045776 22 0.027
glucose import GO:0046323 32 0.026
cyclic nucleotide metabolic process GO:0009187 59 0.026
Mouse
neurotransmitter uptake GO:0001504 14 0.026
gamma aminobutyric acid signaling pathway GO:0007214 8 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
Mouse
cellular response to light stimulus GO:0071482 19 0.026
vesicle localization GO:0051648 86 0.025
phasic smooth muscle contraction GO:0014821 8 0.025
regulation of protein localization GO:0032880 231 0.025
regulation of ion transmembrane transport GO:0034765 119 0.025
mitotic cell cycle GO:0000278 195 0.025
cellular response to amino acid stimulus GO:0071230 29 0.025
monocarboxylic acid metabolic process GO:0032787 191 0.025
cellular metal ion homeostasis GO:0006875 151 0.025
regulation of blood circulation GO:1903522 93 0.025
spermatogenesis GO:0007283 284 0.025
carbohydrate metabolic process GO:0005975 230 0.025
protein localization to organelle GO:0033365 185 0.024
muscle cell differentiation GO:0042692 261 0.024
exploration behavior GO:0035640 21 0.024
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.024
camp metabolic process GO:0046058 40 0.024
Mouse
cytoplasmic transport GO:0016482 234 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
Mouse
carboxylic acid biosynthetic process GO:0046394 86 0.024
telencephalon development GO:0021537 186 0.024
regulation of neuron death GO:1901214 134 0.024
signal transduction in absence of ligand GO:0038034 55 0.024
sensory perception of sound GO:0007605 97 0.024
regulation of system process GO:0044057 200 0.024
small gtpase mediated signal transduction GO:0007264 97 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
negative regulation of cholesterol transport GO:0032375 4 0.023
regulation of cell motility GO:2000145 236 0.023
cellular chemical homeostasis GO:0055082 215 0.023
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.023
response to alkaloid GO:0043279 34 0.023
sterol transport GO:0015918 38 0.023
regulation of blood pressure GO:0008217 93 0.023
endocytosis GO:0006897 168 0.023
protein ubiquitination GO:0016567 171 0.023
synaptic transmission gabaergic GO:0051932 19 0.023
catecholamine transport GO:0051937 21 0.023
detection of external stimulus GO:0009581 61 0.023
Mouse
skeletal system development GO:0001501 356 0.023
positive regulation of nervous system development GO:0051962 221 0.023
corticotropin releasing hormone secretion GO:0043396 2 0.023
regulation of dopamine secretion GO:0014059 9 0.022
negative adaptation of signaling pathway GO:0022401 5 0.022
cellular response to inorganic substance GO:0071241 37 0.022
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.022
proton transport GO:0015992 35 0.022
pigmentation GO:0043473 71 0.022
positive regulation of hormone secretion GO:0046887 38 0.022
monosaccharide metabolic process GO:0005996 106 0.022
regulation of respiratory system process GO:0044065 13 0.022
nuclear division GO:0000280 158 0.022
regulation of protein processing GO:0070613 96 0.022
gliogenesis GO:0042063 141 0.022
regulation of map kinase activity GO:0043405 120 0.022
regulation of sterol transport GO:0032371 17 0.022
detection of visible light GO:0009584 14 0.022
Mouse
fatty acid metabolic process GO:0006631 121 0.022
positive regulation of camp metabolic process GO:0030816 19 0.021
response to inorganic substance GO:0010035 96 0.021
cellular response to peptide hormone stimulus GO:0071375 92 0.021
negative regulation of camp metabolic process GO:0030815 5 0.021
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.021
response to peptide GO:1901652 136 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
cyclic nucleotide biosynthetic process GO:0009190 44 0.021
Mouse
ear development GO:0043583 200 0.021
regulation of the force of heart contraction GO:0002026 17 0.021
positive regulation of growth hormone secretion GO:0060124 3 0.021
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.021
Mouse
protein secretion GO:0009306 111 0.021
multi multicellular organism process GO:0044706 109 0.021
establishment of protein localization to organelle GO:0072594 118 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
regulation of neurotransmitter secretion GO:0046928 29 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
blood circulation GO:0008015 195 0.020
ribose phosphate biosynthetic process GO:0046390 59 0.020
Mouse
chloride transport GO:0006821 32 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.020
negative regulation of lymphocyte activation GO:0051250 91 0.020
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.020
muscle hypertrophy GO:0014896 24 0.020
protein oligomerization GO:0051259 67 0.020
cell division GO:0051301 120 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
detection of stimulus GO:0051606 84 0.020
Mouse
regulation of lyase activity GO:0051339 13 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.020
cellular response to biotic stimulus GO:0071216 92 0.020
Mouse
regulation of nucleotide biosynthetic process GO:0030808 34 0.019
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.019
endocrine process GO:0050886 39 0.019
ras protein signal transduction GO:0007265 77 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
learning GO:0007612 98 0.019
response to nutrient levels GO:0031667 109 0.019
phospholipase c activating dopamine receptor signaling pathway GO:0060158 5 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
Mouse
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.019
response to oxidative stress GO:0006979 123 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
nuclear import GO:0051170 95 0.019
negative regulation of serotonin secretion GO:0014063 2 0.019
regulation of cell cycle GO:0051726 281 0.019
regulation of neuron differentiation GO:0045664 281 0.019
regulation of cell projection organization GO:0031344 206 0.019
gabaergic neuron differentiation GO:0097154 11 0.019
regulation of cysteine type endopeptidase activity GO:2000116 65 0.018
glucan metabolic process GO:0044042 32 0.018
regulation of cyclase activity GO:0031279 13 0.018
alpha amino acid metabolic process GO:1901605 59 0.018
negative regulation of cyclase activity GO:0031280 1 0.018
epithelial cell development GO:0002064 159 0.018
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.018
regulation of protein maturation GO:1903317 96 0.018
vesicle organization GO:0016050 60 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
chemotaxis GO:0006935 247 0.018
positive regulation of peptide hormone secretion GO:0090277 31 0.018
dopamine metabolic process GO:0042417 23 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
cell junction assembly GO:0034329 52 0.018
regulation of dopamine metabolic process GO:0042053 10 0.018
epithelial cell morphogenesis GO:0003382 41 0.018
negative regulation of protein modification process GO:0031400 163 0.018
energy derivation by oxidation of organic compounds GO:0015980 77 0.018
mitotic cell cycle process GO:1903047 159 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
polysaccharide metabolic process GO:0005976 39 0.017
negative regulation of neuron apoptotic process GO:0043524 92 0.017
regulation of cell cycle process GO:0010564 160 0.017
regulation of peptide secretion GO:0002791 77 0.017
lymphocyte proliferation GO:0046651 164 0.017
regulation of response to drug GO:2001023 2 0.017
c21 steroid hormone biosynthetic process GO:0006700 3 0.017
regulation of proteolysis GO:0030162 164 0.017
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 5 0.017
Mouse
monoamine transport GO:0015844 33 0.017
transition metal ion transport GO:0000041 38 0.017
monocarboxylic acid transport GO:0015718 44 0.017
response to temperature stimulus GO:0009266 55 0.016
cell cell junction organization GO:0045216 72 0.016
interneuron migration from the subpallium to the cortex GO:0021830 7 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
positive regulation of organelle organization GO:0010638 128 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
Mouse
regulation of peptidase activity GO:0052547 96 0.016
positive regulation of growth GO:0045927 104 0.016
bone remodeling GO:0046849 53 0.016
cellular response to histamine GO:0071420 1 0.016
male gamete generation GO:0048232 285 0.016
purine nucleoside monophosphate catabolic process GO:0009128 58 0.016
response to alcohol GO:0097305 48 0.016
actin cytoskeleton organization GO:0030036 220 0.016
peristalsis GO:0030432 8 0.016
negative regulation of cell activation GO:0050866 111 0.016
female gamete generation GO:0007292 74 0.016
ensheathment of neurons GO:0007272 76 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
protein targeting GO:0006605 143 0.015
glycogen metabolic process GO:0005977 32 0.015
amine transport GO:0015837 21 0.015
vitamin metabolic process GO:0006766 23 0.015
defecation GO:0030421 1 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.015
cartilage development GO:0051216 140 0.015
gtp catabolic process GO:0006184 143 0.015
protein autophosphorylation GO:0046777 61 0.015
regulation of adenylate cyclase activity GO:0045761 10 0.015
microtubule based process GO:0007017 236 0.015
immune response activating signal transduction GO:0002757 116 0.015

Pde6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.272
disease of anatomical entity DOID:7 0 0.272
eye and adnexa disease DOID:1492 0 0.272
nervous system disease DOID:863 0 0.272
eye disease DOID:5614 0 0.228
retinal disease DOID:5679 0 0.081
retinal degeneration DOID:8466 0 0.031
retinitis pigmentosa DOID:10584 0 0.031
night blindness DOID:8499 0 0.019