Mus musculus

0 known processes

Pbx4

pre-B-cell leukemia homeobox 4

(Aliases: 2410015M21Rik,AI429113,AW045266)

Pbx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myeloid cell differentiation GO:0030099 233 0.083
hematopoietic progenitor cell differentiation GO:0002244 143 0.064
apoptotic signaling pathway GO:0097190 306 0.061
male gamete generation GO:0048232 285 0.057
spermatogenesis GO:0007283 284 0.057
microtubule based process GO:0007017 236 0.047
epithelial tube morphogenesis GO:0060562 303 0.047
Mouse
cellular component assembly involved in morphogenesis GO:0010927 139 0.047
homeostasis of number of cells GO:0048872 210 0.044
determination of left right symmetry GO:0007368 80 0.043
leukocyte differentiation GO:0002521 342 0.042
morphogenesis of embryonic epithelium GO:0016331 159 0.041
dipeptide transport GO:0042938 2 0.038
regionalization GO:0003002 337 0.038
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
inorganic cation transmembrane transport GO:0098662 207 0.037
digestive tract development GO:0048565 190 0.036
Worm
digestive system development GO:0055123 200 0.036
Worm
regulation of ion transmembrane transport GO:0034765 119 0.035
germ cell development GO:0007281 185 0.035
embryonic epithelial tube formation GO:0001838 130 0.035
t cell activation GO:0042110 289 0.034
ion transmembrane transport GO:0034220 361 0.033
organelle assembly GO:0070925 177 0.033
myeloid cell homeostasis GO:0002262 114 0.033
protein kinase b signaling GO:0043491 74 0.032
sensory organ morphogenesis GO:0090596 242 0.031
Zebrafish
organonitrogen compound catabolic process GO:1901565 264 0.031
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.031
cellular ketone metabolic process GO:0042180 84 0.030
nitrogen compound transport GO:0071705 271 0.030
positive regulation of nervous system development GO:0051962 221 0.029
neural tube development GO:0021915 160 0.027
transmembrane transport GO:0055085 412 0.027
gland development GO:0048732 330 0.026
Mouse
muscle cell differentiation GO:0042692 261 0.025
Zebrafish Worm
fat cell differentiation GO:0045444 160 0.025
regulation of cellular component biogenesis GO:0044087 181 0.025
developmental growth involved in morphogenesis GO:0060560 138 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
regulation of fibroblast proliferation GO:0048145 34 0.025
membrane organization GO:0061024 245 0.025
negative regulation of apoptotic signaling pathway GO:2001234 104 0.024
regulation of myeloid cell differentiation GO:0045637 96 0.024
regulation of hydrolase activity GO:0051336 246 0.024
nucleoside triphosphate catabolic process GO:0009143 205 0.024
cilium morphogenesis GO:0060271 102 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
purine containing compound metabolic process GO:0072521 311 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
cellular ion homeostasis GO:0006873 165 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
heterocycle catabolic process GO:0046700 280 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
cellular lipid metabolic process GO:0044255 323 0.023
retina development in camera type eye GO:0060041 119 0.022
Zebrafish
translation GO:0006412 93 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.022
cellular homeostasis GO:0019725 240 0.022
regulation of protein kinase activity GO:0045859 232 0.022
neural tube formation GO:0001841 108 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
blood vessel morphogenesis GO:0048514 285 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
erythrocyte differentiation GO:0030218 88 0.021
regulation of organelle organization GO:0033043 289 0.021
cellular protein complex assembly GO:0043623 116 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
muscle tissue development GO:0060537 308 0.021
Zebrafish
ras protein signal transduction GO:0007265 77 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
negative regulation of nervous system development GO:0051961 156 0.020
Mouse
cell type specific apoptotic process GO:0097285 268 0.020
cell adhesion GO:0007155 329 0.020
macromolecule catabolic process GO:0009057 281 0.020
regulation of transmembrane transport GO:0034762 128 0.020
lymphocyte differentiation GO:0030098 242 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
regulation of cellular catabolic process GO:0031329 242 0.019
lipid localization GO:0010876 126 0.019
Worm
microtubule cytoskeleton organization GO:0000226 157 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
t cell differentiation GO:0030217 174 0.019
cellular amino acid metabolic process GO:0006520 103 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.018
microtubule based movement GO:0007018 84 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
mapk cascade GO:0000165 281 0.018
positive regulation of cell development GO:0010720 237 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
intestinal epithelial structure maintenance GO:0060729 4 0.018
purine containing compound catabolic process GO:0072523 213 0.018
nucleoside metabolic process GO:0009116 246 0.018
camera type eye development GO:0043010 266 0.018
Zebrafish
respiratory tube development GO:0030323 167 0.018
rho protein signal transduction GO:0007266 32 0.018
fibroblast proliferation GO:0048144 35 0.018
purine nucleotide catabolic process GO:0006195 211 0.017
protein maturation GO:0051604 176 0.017
cilium assembly GO:0042384 81 0.017
dna metabolic process GO:0006259 303 0.017
female gamete generation GO:0007292 74 0.017
male sex differentiation GO:0046661 109 0.017
protein catabolic process GO:0030163 221 0.017
cation transmembrane transport GO:0098655 266 0.017
pole plasm assembly GO:0007315 2 0.017
intracellular mrna localization GO:0008298 4 0.017
organophosphate catabolic process GO:0046434 232 0.017
megakaryocyte differentiation GO:0030219 26 0.017
nucleotide metabolic process GO:0009117 332 0.017
sensory perception GO:0007600 245 0.017
epithelial tube formation GO:0072175 130 0.017
regulation of defense response GO:0031347 233 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
skeletal system development GO:0001501 356 0.017
Zebrafish Mouse
cation transport GO:0006812 399 0.017
regulation of ion transmembrane transporter activity GO:0032412 54 0.017
regulation of feeding behavior GO:0060259 3 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
protein localization to membrane GO:0072657 108 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
phospholipid metabolic process GO:0006644 87 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
spermatid differentiation GO:0048515 115 0.016
sequestering of calcium ion GO:0051208 18 0.016
cellular chemical homeostasis GO:0055082 215 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
regulation of transferase activity GO:0051338 263 0.016
nodal signaling pathway GO:0038092 10 0.016
regulation of ion transport GO:0043269 215 0.016
nucleotide catabolic process GO:0009166 217 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
oocyte axis specification GO:0007309 2 0.016
spermatid development GO:0007286 108 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
male meiosis GO:0007140 37 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
muscle system process GO:0003012 141 0.015
amine metabolic process GO:0009308 45 0.015
positive regulation of protein modification process GO:0031401 299 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
cytoplasmic transport GO:0016482 234 0.015
Fly
cation homeostasis GO:0055080 212 0.015
nucleoside catabolic process GO:0009164 206 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
response to growth factor GO:0070848 198 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
negative regulation of molecular function GO:0044092 258 0.015
connective tissue development GO:0061448 179 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of cell projection organization GO:0031344 206 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
metal ion homeostasis GO:0055065 189 0.015
cell maturation GO:0048469 127 0.015
dendrite development GO:0016358 115 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
regulation of cellular amine metabolic process GO:0033238 20 0.014
peptidyl amino acid modification GO:0018193 336 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
small molecule biosynthetic process GO:0044283 132 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
respiratory system development GO:0060541 190 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
protein depolymerization GO:0051261 34 0.014
divalent inorganic cation transport GO:0072511 178 0.014
synaptic transmission GO:0007268 329 0.014
peptide transport GO:0015833 133 0.014
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
divalent metal ion transport GO:0070838 172 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
gonad development GO:0008406 141 0.014
sperm motility GO:0030317 47 0.014
regulation of intracellular transport GO:0032386 159 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
regulation of neuron differentiation GO:0045664 281 0.014
Mouse
aromatic compound catabolic process GO:0019439 286 0.014
cellular amine metabolic process GO:0044106 44 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
gtp catabolic process GO:0006184 143 0.014
lipid biosynthetic process GO:0008610 179 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
mitotic cell cycle process GO:1903047 159 0.014
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
oocyte construction GO:0007308 2 0.013
angiogenesis GO:0001525 201 0.013
organelle fission GO:0048285 170 0.013
primary neural tube formation GO:0014020 95 0.013
regulation of cell cycle GO:0051726 281 0.013
Mouse
regulation of peptide transport GO:0090087 91 0.013
ossification GO:0001503 216 0.013
Mouse
compound eye development GO:0048749 1 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
regulation of cell adhesion GO:0030155 154 0.013
intracellular protein transport GO:0006886 204 0.013
Fly
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
endomembrane system organization GO:0010256 147 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
positive regulation of kinase activity GO:0033674 155 0.013
development of primary sexual characteristics GO:0045137 143 0.013
mitotic cell cycle GO:0000278 195 0.013
Mouse
dephosphorylation GO:0016311 129 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
forebrain development GO:0030900 302 0.013
skeletal system morphogenesis GO:0048705 203 0.013
Zebrafish
neuron death GO:0070997 154 0.013
lens morphogenesis in camera type eye GO:0002089 24 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
positive regulation of fibroblast proliferation GO:0048146 20 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
Mouse
regulation of translation GO:0006417 71 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
Zebrafish
organonitrogen compound biosynthetic process GO:1901566 192 0.012
lateral inhibition GO:0046331 1 0.012
protein localization to organelle GO:0033365 185 0.012
Fly
negative regulation of protein depolymerization GO:1901880 21 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
lung development GO:0030324 164 0.012
regulation of mapk cascade GO:0043408 248 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
regulation of kinase activity GO:0043549 249 0.012
negative regulation of myeloid cell differentiation GO:0045638 38 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
oogenesis GO:0048477 56 0.012
maintenance of location GO:0051235 89 0.012
Worm
epithelial cell proliferation GO:0050673 174 0.012
positive regulation of secretion GO:0051047 130 0.012
negative regulation of cell development GO:0010721 169 0.012
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.012
regulation of hormone levels GO:0010817 211 0.012
cellular response to lipid GO:0071396 145 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
striated muscle contraction GO:0006941 45 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
response to organonitrogen compound GO:0010243 246 0.012
response to light stimulus GO:0009416 135 0.012
negative regulation of cell fate specification GO:0009996 4 0.012
regulation of oligopeptide transport GO:0090088 2 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
organic anion transport GO:0015711 137 0.012
cellular amide metabolic process GO:0043603 58 0.011
positive regulation of cell death GO:0010942 224 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
protein import GO:0017038 101 0.011
Fly
organelle localization GO:0051640 179 0.011
regulation of protein depolymerization GO:1901879 26 0.011
male gonad development GO:0008584 88 0.011
microtubule polymerization or depolymerization GO:0031109 26 0.011
gtp metabolic process GO:0046039 144 0.011
establishment of neuroblast polarity GO:0045200 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
negative regulation of organelle organization GO:0010639 90 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
protein polymerization GO:0051258 57 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.011
response to organic cyclic compound GO:0014070 198 0.011
calcium ion homeostasis GO:0055074 127 0.011
regulation of proteolysis GO:0030162 164 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
male genitalia morphogenesis GO:0048808 4 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
meiotic nuclear division GO:0007126 115 0.011
regulation of cell motility GO:2000145 236 0.011
urogenital system development GO:0001655 261 0.011
Mouse
glycerophospholipid metabolic process GO:0006650 71 0.011
stem cell fate specification GO:0048866 3 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
protein processing GO:0016485 163 0.011
inflammatory response GO:0006954 244 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
Mouse
positive regulation of mapk cascade GO:0043410 170 0.010
asymmetric stem cell division GO:0098722 3 0.010
calcium ion transport GO:0006816 159 0.010
hindbrain development GO:0030902 128 0.010
Zebrafish
morphogenesis of a branching epithelium GO:0061138 193 0.010
Mouse
leukocyte proliferation GO:0070661 172 0.010
muscle contraction GO:0006936 101 0.010
single organism cell adhesion GO:0098602 156 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
developmental maturation GO:0021700 193 0.010
regulation of voltage gated calcium channel activity GO:1901385 4 0.010
epithelial cell development GO:0002064 159 0.010
regulation of secretion GO:0051046 274 0.010
jnk cascade GO:0007254 72 0.010
sulfur compound metabolic process GO:0006790 100 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
regulation of secretion by cell GO:1903530 249 0.010
regulation of cell cycle phase transition GO:1901987 77 0.010
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
circulatory system process GO:0003013 197 0.010
asymmetric neuroblast division GO:0055059 1 0.010
liver development GO:0001889 66 0.010
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
lymphocyte proliferation GO:0046651 164 0.010
negative regulation of protein modification process GO:0031400 163 0.010

Pbx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.017
disease of anatomical entity DOID:7 0 0.017