Mus musculus

134 known processes

Card11

caspase recruitment domain family, member 11

(Aliases: 2410011D02Rik,0610008L17Rik,BIMP3,CARMA1)

Card11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
t cell activation GO:0042110 289 0.975
immune response activating signal transduction GO:0002757 116 0.954
regulation of cell activation GO:0050865 289 0.820
t cell proliferation GO:0042098 120 0.796
dna metabolic process GO:0006259 303 0.792
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.765
immune response regulating signaling pathway GO:0002764 125 0.761
myeloid cell differentiation GO:0030099 233 0.754
regulation of lymphocyte proliferation GO:0050670 117 0.726
regulation of tolerance induction dependent upon immune response GO:0002652 1 0.722
regulation of cytokine biosynthetic process GO:0042035 59 0.683
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.678
leukocyte proliferation GO:0070661 172 0.671
somatic diversification of immune receptors GO:0002200 53 0.655
positive regulation of cytokine biosynthetic process GO:0042108 40 0.630
leukocyte differentiation GO:0002521 342 0.618
neutrophil differentiation GO:0030223 3 0.597
b cell receptor signaling pathway GO:0050853 20 0.595
lymphocyte proliferation GO:0046651 164 0.574
antigen receptor mediated signaling pathway GO:0050851 64 0.570
b cell activation GO:0042113 161 0.545
regulation of t cell activation GO:0050863 170 0.514
regulation of b cell activation GO:0050864 81 0.513
lymphocyte mediated immunity GO:0002449 139 0.506
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.463
regulation of b cell proliferation GO:0030888 39 0.458
b cell proliferation GO:0042100 53 0.456
adaptive immune response GO:0002250 155 0.454
regulation of cytokine production GO:0001817 266 0.441
positive regulation of protein modification process GO:0031401 299 0.440
regulation of intracellular transport GO:0032386 159 0.417
regulation of cellular ketone metabolic process GO:0010565 66 0.414
regulation of lymphocyte activation GO:0051249 240 0.400
cytokine production involved in immune response GO:0002367 34 0.390
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.389
positive regulation of leukocyte proliferation GO:0070665 73 0.371
t cell differentiation GO:0030217 174 0.363
amine metabolic process GO:0009308 45 0.362
regulation of establishment of protein localization GO:0070201 181 0.347
protein modification by small protein conjugation GO:0032446 187 0.336
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.332
Human
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.329
natural killer cell differentiation GO:0001779 21 0.317
positive regulation of cellular amine metabolic process GO:0033240 5 0.314
negative regulation of cellular amine metabolic process GO:0033239 1 0.310
regulation of interleukin 6 production GO:0032675 55 0.309
Mouse
b cell homeostasis GO:0001782 34 0.308
regulation of apoptotic signaling pathway GO:2001233 197 0.307
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.306
cytokine production GO:0001816 319 0.302
innate immune response GO:0045087 157 0.293
Mouse
mucosal associated lymphoid tissue development GO:0048537 12 0.292
cytokine biosynthetic process GO:0042089 68 0.285
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.285
lymphocyte homeostasis GO:0002260 64 0.279
positive regulation of cell death GO:0010942 224 0.277
positive regulation of cytokine production GO:0001819 174 0.270
immature b cell differentiation GO:0002327 10 0.269
activation of immune response GO:0002253 138 0.253
osteoclast differentiation GO:0030316 62 0.243
positive regulation of b cell proliferation GO:0030890 24 0.236
defense response to bacterium GO:0042742 119 0.235
Mouse
regulation of protein localization GO:0032880 231 0.232
extrinsic apoptotic signaling pathway GO:0097191 126 0.230
regulation of hydrolase activity GO:0051336 246 0.217
regulation of myeloid cell differentiation GO:0045637 96 0.214
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.213
cellular ketone metabolic process GO:0042180 84 0.211
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.207
regulation of neutrophil differentiation GO:0045658 2 0.207
regulation of map kinase activity GO:0043405 120 0.203
isotype switching to igg isotypes GO:0048291 10 0.202
negative regulation of leukocyte differentiation GO:1902106 51 0.197
t cell receptor signaling pathway GO:0050852 46 0.195
regulation of leukocyte proliferation GO:0070663 121 0.190
positive regulation of adaptive immune response GO:0002821 61 0.190
regulation of lymphocyte mediated immunity GO:0002706 84 0.186
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.184
antibacterial peptide production GO:0002778 2 0.184
regulation of protein secretion GO:0050708 82 0.181
protein modification by small protein conjugation or removal GO:0070647 207 0.180
cellular amine metabolic process GO:0044106 44 0.180
lymphocyte differentiation GO:0030098 242 0.177
negative regulation of cellular protein metabolic process GO:0032269 247 0.176
negative regulation of protein modification process GO:0031400 163 0.172
regulation of interleukin 8 production GO:0032677 3 0.171
phospholipid metabolic process GO:0006644 87 0.171
regulation of protein transport GO:0051223 163 0.170
homeostasis of number of cells GO:0048872 210 0.168
positive regulation of lymphocyte activation GO:0051251 140 0.168
v d j recombination GO:0033151 14 0.168
regulation of cellular catabolic process GO:0031329 242 0.166
antibacterial humoral response GO:0019731 8 0.166
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.163
regulation of granulocyte differentiation GO:0030852 8 0.163
regulation of myeloid leukocyte differentiation GO:0002761 58 0.161
lymphocyte anergy GO:0002249 4 0.160
positive regulation of kinase activity GO:0033674 155 0.158
humoral immune response GO:0006959 57 0.153
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.152
positive regulation of cell activation GO:0050867 158 0.151
alpha beta t cell activation GO:0046631 91 0.150
immunoglobulin mediated immune response GO:0016064 69 0.150
protein ubiquitination GO:0016567 171 0.146
regulation of cellular amine metabolic process GO:0033238 20 0.145
production of molecular mediator of immune response GO:0002440 103 0.145
regulation of cellular amino acid metabolic process GO:0006521 5 0.145
natural killer cell activation GO:0030101 44 0.140
regulation of lymphocyte differentiation GO:0045619 107 0.139
antimicrobial peptide biosynthetic process GO:0002777 2 0.137
positive regulation of t cell activation GO:0050870 101 0.136
i kappab kinase nf kappab signaling GO:0007249 85 0.134
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.131
necrotic cell death GO:0070265 30 0.131
vocal learning GO:0042297 1 0.130
negative regulation of b cell activation GO:0050869 27 0.125
b cell differentiation GO:0030183 78 0.124
positive regulation of protein phosphorylation GO:0001934 242 0.122
regulation of innate immune response GO:0045088 91 0.122
Mouse
stress activated mapk cascade GO:0051403 80 0.121
Mouse
t cell lineage commitment GO:0002360 13 0.121
regulation of kinase activity GO:0043549 249 0.118
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.116
t cell mediated immunity GO:0002456 50 0.116
endocytosis GO:0006897 168 0.116
thymus development GO:0048538 41 0.114
regulation of endopeptidase activity GO:0052548 89 0.114
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.113
epithelial tube morphogenesis GO:0060562 303 0.111
camera type eye development GO:0043010 266 0.111
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.109
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.108
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.107
regulation of binding GO:0051098 111 0.106
positive regulation of regulatory t cell differentiation GO:0045591 4 0.106
positive regulation of hydrolase activity GO:0051345 148 0.105
regulation of stress activated mapk cascade GO:0032872 69 0.104
Mouse
regulation of immunoglobulin production GO:0002637 42 0.104
stress activated protein kinase signaling cascade GO:0031098 81 0.102
Mouse
cellular amino acid metabolic process GO:0006520 103 0.099
morphogenesis of embryonic epithelium GO:0016331 159 0.099
negative regulation of dna recombination GO:0045910 13 0.099
cellular response to external stimulus GO:0071496 88 0.097
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.097
positive regulation of mapk cascade GO:0043410 170 0.097
Mouse
inflammatory response GO:0006954 244 0.095
leukocyte mediated immunity GO:0002443 174 0.095
alpha beta t cell differentiation GO:0046632 69 0.094
negative regulation of immune system process GO:0002683 209 0.093
transforming growth factor beta1 production GO:0032905 3 0.093
t cell differentiation in thymus GO:0033077 77 0.092
negative regulation of phosphorus metabolic process GO:0010563 184 0.091
regulation of epithelial cell proliferation GO:0050678 141 0.091
protein oligomerization GO:0051259 67 0.090
autophagy GO:0006914 45 0.090
b cell activation involved in immune response GO:0002312 50 0.090
erythrocyte differentiation GO:0030218 88 0.089
protein secretion GO:0009306 111 0.089
positive regulation of endopeptidase activity GO:0010950 43 0.089
negative regulation of adaptive immune response GO:0002820 25 0.088
positive regulation of myeloid cell differentiation GO:0045639 43 0.088
tube closure GO:0060606 91 0.087
regulation of protein kinase activity GO:0045859 232 0.087
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.086
regulation of interleukin 18 production GO:0032661 3 0.085
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.085
negative regulation of t cell activation GO:0050868 65 0.085
regulation of transferase activity GO:0051338 263 0.085
dna recombination GO:0006310 92 0.084
regulation of b cell differentiation GO:0045577 23 0.084
regulation of protein serine threonine kinase activity GO:0071900 157 0.083
endodermal cell fate specification GO:0001714 4 0.083
negative regulation of lymphocyte activation GO:0051250 91 0.082
antibacterial peptide biosynthetic process GO:0002780 2 0.082
retina development in camera type eye GO:0060041 119 0.082
neural tube closure GO:0001843 90 0.082
negative regulation of interleukin 2 biosynthetic process GO:0045085 3 0.082
negative regulation of interleukin 2 production GO:0032703 8 0.081
chronic inflammatory response GO:0002544 9 0.080
negative regulation of intracellular signal transduction GO:1902532 167 0.080
positive regulation of leukocyte mediated immunity GO:0002705 70 0.079
epithelial cell proliferation GO:0050673 174 0.079
t cell anergy GO:0002870 4 0.079
t helper 2 cell differentiation GO:0045064 12 0.078
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.078
necroptotic process GO:0070266 21 0.078
response to organic cyclic compound GO:0014070 198 0.077
Mouse
immune effector process GO:0002252 321 0.076
Mouse
negative regulation of defense response GO:0031348 77 0.075
establishment of protein localization to organelle GO:0072594 118 0.075
calcium ion transport GO:0006816 159 0.074
divalent metal ion transport GO:0070838 172 0.074
negative regulation of nik nf kappab signaling GO:1901223 2 0.074
negative regulation of myeloid cell differentiation GO:0045638 38 0.074
regulation of peptidase activity GO:0052547 96 0.073
positive regulation of neuron differentiation GO:0045666 141 0.073
t helper 17 cell differentiation GO:0072539 7 0.073
interferon gamma production GO:0032609 67 0.072
embryonic epithelial tube formation GO:0001838 130 0.072
cellular protein complex assembly GO:0043623 116 0.072
neural tube formation GO:0001841 108 0.071
muscle cell differentiation GO:0042692 261 0.071
regulation of b cell apoptotic process GO:0002902 13 0.071
cellular response to molecule of bacterial origin GO:0071219 83 0.071
b cell mediated immunity GO:0019724 71 0.070
positive regulation of granulocyte differentiation GO:0030854 3 0.070
regulation of cytoplasmic transport GO:1903649 112 0.070
anatomical structure homeostasis GO:0060249 145 0.069
hematopoietic progenitor cell differentiation GO:0002244 143 0.069
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.069
intrinsic apoptotic signaling pathway GO:0097193 132 0.069
cell fate commitment GO:0045165 210 0.069
leukocyte apoptotic process GO:0071887 71 0.068
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.068
positive regulation of b cell activation GO:0050871 49 0.068
cellular response to oxidative stress GO:0034599 76 0.067
regulation of interleukin 1 production GO:0032652 26 0.067
regulation of mapk cascade GO:0043408 248 0.067
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.067
negative regulation of phosphorylation GO:0042326 166 0.067
positive regulation of map kinase activity GO:0043406 84 0.066
regulation of t cell proliferation GO:0042129 92 0.065
innate immune response in mucosa GO:0002227 3 0.064
organelle assembly GO:0070925 177 0.064
regulation of cysteine type endopeptidase activity GO:2000116 65 0.063
negative regulation of molecular function GO:0044092 258 0.063
respiratory system development GO:0060541 190 0.062
positive regulation of programmed cell death GO:0043068 218 0.062
stem cell differentiation GO:0048863 268 0.062
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.061
type i interferon production GO:0032606 29 0.060
peptidyl amino acid modification GO:0018193 336 0.060
regulation of cell size GO:0008361 72 0.060
interleukin 8 production GO:0032637 4 0.060
cellular response to abiotic stimulus GO:0071214 56 0.059
cellular response to lipid GO:0071396 145 0.059
mechanosensory behavior GO:0007638 6 0.059
negative regulation of cell proliferation GO:0008285 296 0.059
cellular lipid metabolic process GO:0044255 323 0.059
primary neural tube formation GO:0014020 95 0.059
regulation of cellular response to stress GO:0080135 159 0.058
Mouse
positive regulation of apoptotic process GO:0043065 217 0.058
regulation of metal ion transport GO:0010959 106 0.058
antimicrobial peptide production GO:0002775 2 0.058
positive regulation of defense response to bacterium GO:1900426 1 0.057
programmed necrotic cell death GO:0097300 28 0.057
positive regulation of protein kinase activity GO:0045860 144 0.057
positive regulation of protein transport GO:0051222 93 0.057
interleukin 12 production GO:0032615 32 0.057
actin cytoskeleton organization GO:0030036 220 0.057
tissue remodeling GO:0048771 102 0.056
regulation of defense response GO:0031347 233 0.056
Mouse
organ growth GO:0035265 117 0.056
regulation of alpha beta t cell differentiation GO:0046637 35 0.056
negative regulation of intracellular protein transport GO:0090317 27 0.055
positive regulation of defense response GO:0031349 124 0.055
Mouse
chromatin organization GO:0006325 206 0.055
response to acid chemical GO:0001101 111 0.054
regulation of immunoglobulin mediated immune response GO:0002889 37 0.054
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.054
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.054
cellular metal ion homeostasis GO:0006875 151 0.054
covalent chromatin modification GO:0016569 163 0.053
positive regulation of interferon alpha production GO:0032727 4 0.053
negative regulation of multi organism process GO:0043901 68 0.053
negative regulation of interleukin 5 production GO:0032714 4 0.053
histamine production involved in inflammatory response GO:0002349 1 0.052
regulation of lymphocyte anergy GO:0002911 4 0.052
negative regulation of immune effector process GO:0002698 55 0.052
isotype switching GO:0045190 36 0.052
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.052
histone modification GO:0016570 159 0.052
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.051
Human
activation of nf kappab inducing kinase activity GO:0007250 4 0.051
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.051
myeloid dendritic cell activation GO:0001773 25 0.051
cell type specific apoptotic process GO:0097285 268 0.051
regulation of interleukin 8 secretion GO:2000482 2 0.051
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.050
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.050
regulation of t cell anergy GO:0002667 4 0.050
positive t cell selection GO:0043368 23 0.050
regulation of autophagy GO:0010506 30 0.050
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.050
chromatin modification GO:0016568 187 0.049
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.049
cardiac muscle cell differentiation GO:0055007 69 0.049
interleukin 8 secretion GO:0072606 3 0.048
positive regulation of peptidase activity GO:0010952 49 0.048
negative regulation of protein metabolic process GO:0051248 282 0.048
regulation of fibroblast proliferation GO:0048145 34 0.048
positive regulation of b cell differentiation GO:0045579 13 0.047
regulation of response to biotic stimulus GO:0002831 38 0.047
epithelial tube formation GO:0072175 130 0.047
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.047
regulation of b cell mediated immunity GO:0002712 37 0.047
regulation of dna recombination GO:0000018 34 0.047
regulation of cellular component biogenesis GO:0044087 181 0.047
cytokine secretion GO:0050663 72 0.047
innate immune response activating signal transduction GO:0002758 50 0.046
regulation of striated muscle cell differentiation GO:0051153 81 0.046
cd4 positive cd25 positive alpha beta regulatory t cell differentiation GO:0002361 4 0.046
regulation of leukocyte differentiation GO:1902105 159 0.045
cation transport GO:0006812 399 0.045
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.045
myeloid leukocyte differentiation GO:0002573 119 0.045
peptidyl tyrosine phosphorylation GO:0018108 143 0.044
immune response inhibiting signal transduction GO:0002765 4 0.044
cellular response to biotic stimulus GO:0071216 92 0.044
somatic diversification of immunoglobulins GO:0016445 43 0.044
syncytium formation by plasma membrane fusion GO:0000768 42 0.044
positive regulation of proteolysis GO:0045862 85 0.044
bone resorption GO:0045453 38 0.043
neural tube development GO:0021915 160 0.043
negative regulation of tumor necrosis factor production GO:0032720 17 0.043
forebrain development GO:0030900 302 0.042
regulation of proteolysis GO:0030162 164 0.042
inflammatory response to antigenic stimulus GO:0002437 30 0.042
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.042
regulation of toll like receptor signaling pathway GO:0034121 20 0.042
regulation of lipid kinase activity GO:0043550 14 0.042
skeletal muscle organ development GO:0060538 163 0.041
negative regulation of phosphate metabolic process GO:0045936 184 0.041
leukocyte homeostasis GO:0001776 79 0.041
regulation of multi organism process GO:0043900 111 0.041
regulation of antimicrobial peptide production GO:0002784 1 0.041
nuclear transport GO:0051169 139 0.041
regulation of endocytosis GO:0030100 69 0.041
negative regulation of lymphocyte differentiation GO:0045620 32 0.040
regulation of alpha beta t cell activation GO:0046634 53 0.040
regulation of secretion by cell GO:1903530 249 0.040
positive regulation of cell development GO:0010720 237 0.040
regulation of t cell receptor signaling pathway GO:0050856 21 0.040
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.040
positive regulation of immune effector process GO:0002699 107 0.039
interleukin 10 secretion GO:0072608 4 0.039
cytosolic calcium ion homeostasis GO:0051480 70 0.039
toll like receptor signaling pathway GO:0002224 38 0.039
ras protein signal transduction GO:0007265 77 0.039
negative regulation of protein phosphorylation GO:0001933 126 0.039
odontogenesis GO:0042476 78 0.039
tube formation GO:0035148 140 0.039
ubiquitin dependent protein catabolic process GO:0006511 129 0.039
negative regulation of regulatory t cell differentiation GO:0045590 2 0.039
regulation of antibacterial peptide production GO:0002786 1 0.038
immunoglobulin production GO:0002377 73 0.038
cytokine metabolic process GO:0042107 71 0.038
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.038
axonogenesis GO:0007409 274 0.038
translational initiation GO:0006413 24 0.038
regulation of lipid metabolic process GO:0019216 118 0.037
granulocyte differentiation GO:0030851 17 0.037
positive regulation of binding GO:0051099 49 0.037
protein homooligomerization GO:0051260 43 0.037
striated muscle cell development GO:0055002 125 0.037
defense response to other organism GO:0098542 197 0.037
Mouse
intracellular protein transport GO:0006886 204 0.037
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.037
metal ion homeostasis GO:0055065 189 0.037
cellular calcium ion homeostasis GO:0006874 119 0.037
positive regulation of secretion by cell GO:1903532 114 0.037
positive regulation of lymphocyte proliferation GO:0050671 70 0.036
jnk cascade GO:0007254 72 0.036
Mouse
regulation of cytokine secretion GO:0050707 61 0.036
t cell apoptotic process GO:0070231 39 0.036
divalent inorganic cation homeostasis GO:0072507 138 0.036
protein processing GO:0016485 163 0.036
gland development GO:0048732 330 0.035
meiotic cell cycle GO:0051321 122 0.035
muscle tissue development GO:0060537 308 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.035
t cell selection GO:0045058 34 0.035
positive regulation of cytokine secretion GO:0050715 41 0.035
muscle cell fate specification GO:0042694 1 0.034
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.034
positive regulation of growth GO:0045927 104 0.034
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.034
positive regulation of alpha beta t cell activation GO:0046635 39 0.034
lymph node development GO:0048535 18 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.034
regulation of neuron projection development GO:0010975 169 0.034
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.034
nephron development GO:0072006 109 0.034
guanosine containing compound metabolic process GO:1901068 144 0.034
cellular response to acid chemical GO:0071229 68 0.034
glial cell apoptotic process GO:0034349 3 0.034
positive regulation of striated muscle cell differentiation GO:0051155 35 0.033
developmental maturation GO:0021700 193 0.033
response to organonitrogen compound GO:0010243 246 0.033
Mouse
nucleocytoplasmic transport GO:0006913 139 0.033
regulation of system process GO:0044057 200 0.033
regulation of protein localization to nucleus GO:1900180 60 0.033
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.033
regulation of anatomical structure size GO:0090066 178 0.033
cellular response to hormone stimulus GO:0032870 150 0.033
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.033
release of sequestered calcium ion into cytosol GO:0051209 42 0.033
regulation of cell projection organization GO:0031344 206 0.032
protein maturation GO:0051604 176 0.032
regulation of interleukin 2 production GO:0032663 28 0.032
defense response to virus GO:0051607 68 0.032
Mouse
regulation of isotype switching GO:0045191 22 0.032
negative regulation of osteoclast differentiation GO:0045671 12 0.032
regulation of actin polymerization or depolymerization GO:0008064 45 0.032
regulation of actin filament based process GO:0032970 99 0.032
sensory perception GO:0007600 245 0.032
negative regulation of t cell mediated immunity GO:0002710 9 0.032
positive regulation of innate immune response GO:0045089 80 0.032
Mouse
axon guidance GO:0007411 141 0.032
histone h3 acetylation GO:0043966 14 0.031
tyrosine phosphorylation of stat protein GO:0007260 23 0.031
phosphatidylinositol metabolic process GO:0046488 45 0.031
glycerolipid metabolic process GO:0046486 122 0.031
immunoglobulin secretion GO:0048305 17 0.031
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.031
apoptotic signaling pathway GO:0097190 306 0.031
regulation of inflammatory response GO:0050727 147 0.031
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.031
synaptic transmission GO:0007268 329 0.031
somatic recombination of t cell receptor gene segments GO:0002681 5 0.030
protein acylation GO:0043543 64 0.030
protein alkylation GO:0008213 81 0.030
t helper 17 type immune response GO:0072538 9 0.030
detection of molecule of bacterial origin GO:0032490 2 0.030
response to hyperoxia GO:0055093 2 0.030
compound eye development GO:0048749 1 0.029
imitative learning GO:0098596 1 0.029
learned vocalization behavior or vocal learning GO:0098598 1 0.029
positive regulation of b cell mediated immunity GO:0002714 26 0.029
negative regulation of growth of symbiont in host GO:0044130 19 0.029
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.029
renal system development GO:0072001 225 0.029
telomere capping GO:0016233 4 0.029
ribonucleoside catabolic process GO:0042454 206 0.029
skeletal system morphogenesis GO:0048705 203 0.029
peyer s patch development GO:0048541 12 0.029
actomyosin structure organization GO:0031032 56 0.029
immunoglobulin v d j recombination GO:0033152 5 0.029
negative regulation of synapse assembly GO:0051964 3 0.029
b cell lineage commitment GO:0002326 4 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
regulation of cellular component size GO:0032535 121 0.029
positive regulation of release of cytochrome c from mitochondria GO:0090200 5 0.029
positive regulation of apoptotic signaling pathway GO:2001235 95 0.028
negative regulation of growth GO:0045926 99 0.028
negative regulation of organelle organization GO:0010639 90 0.028
regulation of isotype switching to ige isotypes GO:0048293 7 0.028
positive regulation of ion transport GO:0043270 65 0.028
b cell apoptotic process GO:0001783 19 0.028
negative regulation of interferon gamma production GO:0032689 18 0.028
multicellular organismal homeostasis GO:0048871 164 0.028
cardiocyte differentiation GO:0035051 87 0.027
positive regulation of interleukin 8 production GO:0032757 2 0.027
methylation GO:0032259 134 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
response to transforming growth factor beta GO:0071559 88 0.027
negative regulation of t cell differentiation GO:0045581 23 0.027
negative regulation of lymphocyte proliferation GO:0050672 45 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
metanephros development GO:0001656 79 0.027
positive regulation of transferase activity GO:0051347 167 0.027
respiratory tube development GO:0030323 167 0.027
digestive system development GO:0055123 200 0.027
fibroblast proliferation GO:0048144 35 0.027
multicellular organism growth GO:0035264 161 0.026
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.026
myotube differentiation GO:0014902 105 0.026
negative regulation of creb transcription factor activity GO:0032792 2 0.026
kidney epithelium development GO:0072073 121 0.026
protein localization to nucleus GO:0034504 121 0.026
jak stat cascade GO:0007259 42 0.026
regulation of interleukin 1 beta production GO:0032651 25 0.026
alpha beta t cell lineage commitment GO:0002363 7 0.026
positive regulation of chronic inflammatory response GO:0002678 4 0.026
regulation of alpha beta t cell proliferation GO:0046640 18 0.026
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.026
regulation of ion transport GO:0043269 215 0.026
positive regulation of t cell differentiation GO:0045582 52 0.026
negative regulation of toll like receptor 2 signaling pathway GO:0034136 3 0.026
regulation of production of molecular mediator of immune response GO:0002700 65 0.026
negative regulation of cytoplasmic transport GO:1903650 29 0.026
odontogenesis of dentin containing tooth GO:0042475 66 0.025

Card11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
primary immunodeficiency disease DOID:612 0 0.311
immune system disease DOID:2914 0 0.311
disease of anatomical entity DOID:7 0 0.311
b cell deficiency DOID:2115 0 0.311
blood protein disease DOID:620 0 0.062
agammaglobulinemia DOID:2583 0 0.062
common variable immunodeficiency DOID:12177 0 0.062
hematopoietic system disease DOID:74 0 0.062
cancer DOID:162 0 0.045
disease of cellular proliferation DOID:14566 0 0.045
organ system cancer DOID:0050686 0 0.045
disease of metabolism DOID:0014667 0 0.040
acquired metabolic disease DOID:0060158 0 0.040
diabetes mellitus DOID:9351 0 0.031
carbohydrate metabolism disease DOID:0050013 0 0.031
glucose metabolism disease DOID:4194 0 0.031