Mus musculus

24 known processes

Pcsk6

proprotein convertase subtilisin/kexin type 6

(Aliases: SPC4,C86343,Pace4)

Pcsk6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage development GO:0048736 166 0.646
Mouse
embryonic organ morphogenesis GO:0048562 276 0.265
positive regulation of cellular amine metabolic process GO:0033240 5 0.253
regulation of cellular amine metabolic process GO:0033238 20 0.232
bone development GO:0060348 120 0.219
gland development GO:0048732 330 0.218
cellular amino acid metabolic process GO:0006520 103 0.215
axonogenesis GO:0007409 274 0.196
skeletal system development GO:0001501 356 0.182
Mouse
epithelial tube morphogenesis GO:0060562 303 0.181
forebrain development GO:0030900 302 0.180
regulation of cellular amino acid metabolic process GO:0006521 5 0.176
telencephalon development GO:0021537 186 0.156
cartilage development GO:0051216 140 0.156
limb development GO:0060173 166 0.144
Mouse
cellular lipid metabolic process GO:0044255 323 0.138
morphogenesis of embryonic epithelium GO:0016331 159 0.137
embryonic epithelial tube formation GO:0001838 130 0.137
axial mesoderm formation GO:0048320 3 0.133
regionalization GO:0003002 337 0.132
negative regulation of cell proliferation GO:0008285 296 0.132
developmental cell growth GO:0048588 84 0.132
camera type eye development GO:0043010 266 0.128
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.124
regulation of cellular component size GO:0032535 121 0.122
regulation of proteolysis GO:0030162 164 0.119
appendage morphogenesis GO:0035107 149 0.118
Mouse
urogenital system development GO:0001655 261 0.116
Mouse
regulation of cell projection organization GO:0031344 206 0.112
regulation of secretion GO:0051046 274 0.111
stem cell development GO:0048864 219 0.109
connective tissue development GO:0061448 179 0.108
transmembrane transport GO:0055085 412 0.106
ameboidal type cell migration GO:0001667 128 0.106
blood vessel morphogenesis GO:0048514 285 0.105
skeletal system morphogenesis GO:0048705 203 0.104
negative regulation of neuron projection development GO:0010977 50 0.104
renal system development GO:0072001 225 0.103
Mouse
heart morphogenesis GO:0003007 178 0.103
mesenchyme development GO:0060485 152 0.102
nitrogen compound transport GO:0071705 271 0.100
digestive tract development GO:0048565 190 0.098
Mouse
kidney development GO:0001822 213 0.098
Mouse
striated muscle tissue development GO:0014706 293 0.095
cellular ketone metabolic process GO:0042180 84 0.094
metencephalon development GO:0022037 89 0.093
metal ion homeostasis GO:0055065 189 0.092
muscle tissue development GO:0060537 308 0.092
regulation of endopeptidase activity GO:0052548 89 0.091
neuron projection guidance GO:0097485 141 0.089
nucleobase containing small molecule metabolic process GO:0055086 352 0.089
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.086
neural tube formation GO:0001841 108 0.086
ossification GO:0001503 216 0.086
respiratory system development GO:0060541 190 0.085
axon guidance GO:0007411 141 0.083
regulation of hormone levels GO:0010817 211 0.083
Human Mouse Rat
epithelial tube formation GO:0072175 130 0.083
regulation of protein kinase activity GO:0045859 232 0.083
positive regulation of cellular catabolic process GO:0031331 148 0.080
positive regulation of protein phosphorylation GO:0001934 242 0.079
developmental growth involved in morphogenesis GO:0060560 138 0.078
organic acid transport GO:0015849 101 0.078
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.078
regulation of kinase activity GO:0043549 249 0.077
stem cell differentiation GO:0048863 268 0.077
primary neural tube formation GO:0014020 95 0.076
morphogenesis of a branching structure GO:0001763 203 0.076
neural tube development GO:0021915 160 0.075
skin development GO:0043588 220 0.075
regulation of reproductive process GO:2000241 66 0.075
positive regulation of protein modification process GO:0031401 299 0.075
cerebellum development GO:0021549 77 0.073
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.073
digestive tract morphogenesis GO:0048546 147 0.072
tube formation GO:0035148 140 0.072
cardiac septum development GO:0003279 59 0.071
protein maturation GO:0051604 176 0.071
Human Yeast Mouse Rat
limb morphogenesis GO:0035108 149 0.071
Mouse
cation transmembrane transport GO:0098655 266 0.071
chondrocyte differentiation GO:0002062 72 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
mesendoderm development GO:0048382 3 0.071
alpha amino acid metabolic process GO:1901605 59 0.071
cellular amine metabolic process GO:0044106 44 0.069
regulation of cellular ketone metabolic process GO:0010565 66 0.069
regulation of peptidase activity GO:0052547 96 0.069
positive regulation of nervous system development GO:0051962 221 0.068
bone morphogenesis GO:0060349 78 0.068
cytokine production GO:0001816 319 0.068
Mouse
germ cell development GO:0007281 185 0.068
Mouse
hormone secretion GO:0046879 128 0.067
regulation of osteoblast differentiation GO:0045667 67 0.067
positive regulation of programmed cell death GO:0043068 218 0.067
regulation of neuron projection development GO:0010975 169 0.066
sensory perception GO:0007600 245 0.066
neuron projection extension GO:1990138 64 0.066
neuron migration GO:0001764 122 0.065
developmental maturation GO:0021700 193 0.065
Mouse
tissue remodeling GO:0048771 102 0.064
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.064
multicellular organismal homeostasis GO:0048871 164 0.063
negative regulation of cellular amine metabolic process GO:0033239 1 0.062
organic hydroxy compound biosynthetic process GO:1901617 77 0.062
negative regulation of protein metabolic process GO:0051248 282 0.062
regulation of neuron differentiation GO:0045664 281 0.061
ion transmembrane transport GO:0034220 361 0.061
digestive system development GO:0055123 200 0.061
Mouse
positive regulation of apoptotic process GO:0043065 217 0.061
mesenchymal cell differentiation GO:0048762 107 0.059
cation homeostasis GO:0055080 212 0.059
negative regulation of hydrolase activity GO:0051346 71 0.058
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.058
negative regulation of cellular protein metabolic process GO:0032269 247 0.058
sensory organ morphogenesis GO:0090596 242 0.058
regulation of cell adhesion GO:0030155 154 0.058
neuron death GO:0070997 154 0.058
carbohydrate metabolic process GO:0005975 230 0.058
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.057
cellular modified amino acid metabolic process GO:0006575 63 0.057
purine ribonucleotide metabolic process GO:0009150 290 0.057
acetylcholine transport GO:0015870 2 0.057
nucleoside phosphate metabolic process GO:0006753 338 0.056
hindbrain development GO:0030902 128 0.056
nucleotide metabolic process GO:0009117 332 0.056
muscle cell differentiation GO:0042692 261 0.056
amine metabolic process GO:0009308 45 0.055
ribose phosphate metabolic process GO:0019693 291 0.055
odontogenesis of dentin containing tooth GO:0042475 66 0.055
mapk cascade GO:0000165 281 0.055
ribonucleotide metabolic process GO:0009259 291 0.055
regulation of cellular catabolic process GO:0031329 242 0.055
fat cell differentiation GO:0045444 160 0.054
spermatogenesis GO:0007283 284 0.054
Mouse
cell substrate adhesion GO:0031589 130 0.053
regulation of ossification GO:0030278 112 0.053
cell maturation GO:0048469 127 0.053
Mouse
cell fate commitment GO:0045165 210 0.053
branching morphogenesis of an epithelial tube GO:0048754 159 0.053
gastrulation GO:0007369 116 0.053
regulation of ion transmembrane transport GO:0034765 119 0.052
cytoplasmic transport GO:0016482 234 0.052
tube closure GO:0060606 91 0.052
insulin secretion GO:0030073 89 0.052
organonitrogen compound biosynthetic process GO:1901566 192 0.051
Mouse
tendon formation GO:0035992 4 0.051
negative regulation of cell development GO:0010721 169 0.050
regulation of hydrolase activity GO:0051336 246 0.050
angiogenesis GO:0001525 201 0.050
organic anion transport GO:0015711 137 0.050
protein targeting GO:0006605 143 0.050
pallium development GO:0021543 120 0.050
regulation of mapk cascade GO:0043408 248 0.050
stem cell proliferation GO:0072089 117 0.050
cellular carbohydrate metabolic process GO:0044262 119 0.050
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.050
coenzyme metabolic process GO:0006732 52 0.050
retina development in camera type eye GO:0060041 119 0.049
regulation of extent of cell growth GO:0061387 52 0.049
microtubule based process GO:0007017 236 0.049
ventricular cardiac muscle cell action potential GO:0086005 4 0.048
protein localization to membrane GO:0072657 108 0.048
synaptic transmission GO:0007268 329 0.048
energy derivation by oxidation of organic compounds GO:0015980 77 0.048
lung development GO:0030324 164 0.048
respiratory tube development GO:0030323 167 0.047
Mouse
protein localization to nucleus GO:0034504 121 0.047
odontogenesis GO:0042476 78 0.047
positive regulation of mapk cascade GO:0043410 170 0.047
amide transport GO:0042886 138 0.047
positive regulation of cell death GO:0010942 224 0.046
organic acid catabolic process GO:0016054 51 0.046
endomembrane system organization GO:0010256 147 0.046
anion transport GO:0006820 177 0.045
purine nucleoside metabolic process GO:0042278 241 0.045
positive regulation of cell development GO:0010720 237 0.045
organic hydroxy compound metabolic process GO:1901615 203 0.045
regulation of stem cell proliferation GO:0072091 78 0.044
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.044
acylglycerol metabolic process GO:0006639 55 0.043
ribonucleoside metabolic process GO:0009119 245 0.043
regulation of homeostatic process GO:0032844 182 0.043
carbohydrate biosynthetic process GO:0016051 74 0.043
ammonia assimilation cycle GO:0019676 2 0.043
cardiac chamber morphogenesis GO:0003206 93 0.043
regulation of cytokine production GO:0001817 266 0.043
myeloid leukocyte differentiation GO:0002573 119 0.043
embryonic limb morphogenesis GO:0030326 126 0.042
epidermis development GO:0008544 187 0.042
cation transport GO:0006812 399 0.042
negative regulation of molecular function GO:0044092 258 0.042
macromolecule catabolic process GO:0009057 281 0.041
establishment of protein localization to organelle GO:0072594 118 0.041
morphogenesis of a branching epithelium GO:0061138 193 0.041
carboxylic acid catabolic process GO:0046395 51 0.041
diencephalon development GO:0021536 63 0.041
dna metabolic process GO:0006259 303 0.040
regulation of cell cycle GO:0051726 281 0.040
morphogenesis of an epithelial fold GO:0060571 28 0.040
regulation of cell size GO:0008361 72 0.040
response to organic cyclic compound GO:0014070 198 0.040
neural precursor cell proliferation GO:0061351 121 0.039
positive regulation of cell projection organization GO:0031346 95 0.039
embryonic camera type eye development GO:0031076 36 0.039
cellular chemical homeostasis GO:0055082 215 0.039
lipid catabolic process GO:0016042 69 0.039
cell adhesion GO:0007155 329 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.039
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.039
anatomical structure homeostasis GO:0060249 145 0.039
negative regulation of synapse assembly GO:0051964 3 0.038
cell type specific apoptotic process GO:0097285 268 0.038
nucleoside metabolic process GO:0009116 246 0.038
chemotaxis GO:0006935 247 0.038
amino acid transport GO:0006865 61 0.038
sulfur compound metabolic process GO:0006790 100 0.038
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.038
action potential GO:0001508 78 0.038
regulation of system process GO:0044057 200 0.037
regulation of cell activation GO:0050865 289 0.037
kidney epithelium development GO:0072073 121 0.037
one carbon metabolic process GO:0006730 1 0.037
placenta development GO:0001890 140 0.037
cellular response to lipid GO:0071396 145 0.037
regulation of wnt signaling pathway GO:0030111 123 0.037
cellular response to growth factor stimulus GO:0071363 197 0.037
oxidation reduction process GO:0055114 342 0.037
inorganic ion transmembrane transport GO:0098660 234 0.037
mesenchymal cell development GO:0014031 93 0.037
spermatid differentiation GO:0048515 115 0.036
Mouse
t cell activation GO:0042110 289 0.036
monocarboxylic acid metabolic process GO:0032787 191 0.036
mammary gland duct morphogenesis GO:0060603 38 0.036
carbohydrate homeostasis GO:0033500 128 0.036
nucleocytoplasmic transport GO:0006913 139 0.036
negative regulation of neuron differentiation GO:0045665 101 0.036
cardiocyte differentiation GO:0035051 87 0.036
neuronal action potential GO:0019228 54 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.036
regulation of body fluid levels GO:0050878 162 0.036
male sex differentiation GO:0046661 109 0.036
extracellular structure organization GO:0043062 148 0.035
circulatory system process GO:0003013 197 0.035
cardiac ventricle development GO:0003231 83 0.035
regulation of cartilage development GO:0061035 44 0.035
cytokine biosynthetic process GO:0042089 68 0.035
Mouse
purine containing compound metabolic process GO:0072521 311 0.035
peptide secretion GO:0002790 114 0.035
t cell differentiation in thymus GO:0033077 77 0.035
regulation of chondrocyte differentiation GO:0032330 33 0.035
formation of primary germ layer GO:0001704 77 0.035
cytokine metabolic process GO:0042107 71 0.035
Mouse
locomotory behavior GO:0007626 195 0.035
regulation of protein maturation GO:1903317 96 0.035
mammary gland epithelium development GO:0061180 65 0.034
ensheathment of neurons GO:0007272 76 0.034
regulation of cell migration GO:0030334 219 0.034
regulation of secretion by cell GO:1903530 249 0.034
nuclear import GO:0051170 95 0.034
positive regulation of protein kinase activity GO:0045860 144 0.034
regulation of organ morphogenesis GO:2000027 144 0.034
tendon cell differentiation GO:0035990 4 0.034
carboxylic acid transport GO:0046942 100 0.034
leukocyte differentiation GO:0002521 342 0.034
embryonic skeletal system development GO:0048706 120 0.034
Mouse
glycosyl compound metabolic process GO:1901657 246 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
stem cell maintenance GO:0019827 130 0.033
somatic stem cell maintenance GO:0035019 47 0.033
response to acid chemical GO:0001101 111 0.033
regulation of peptide transport GO:0090087 91 0.033
segmentation GO:0035282 93 0.033
regulation of anatomical structure size GO:0090066 178 0.033
monosaccharide biosynthetic process GO:0046364 44 0.033
cellular homeostasis GO:0019725 240 0.033
spermatid development GO:0007286 108 0.033
Mouse
regulation of binding GO:0051098 111 0.032
steroid metabolic process GO:0008202 119 0.032
regulation of neuron apoptotic process GO:0043523 122 0.032
lipid localization GO:0010876 126 0.032
inorganic cation transmembrane transport GO:0098662 207 0.032
regulation of membrane potential GO:0042391 192 0.032
alcohol metabolic process GO:0006066 116 0.032
regulation of cell substrate adhesion GO:0010810 73 0.032
dephosphorylation GO:0016311 129 0.032
neural tube closure GO:0001843 90 0.032
limbic system development GO:0021761 72 0.031
gonad development GO:0008406 141 0.031
membrane organization GO:0061024 245 0.031
endodermal cell fate specification GO:0001714 4 0.031
nucleoside triphosphate catabolic process GO:0009143 205 0.031
positive regulation of lymphocyte activation GO:0051251 140 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.031
positive regulation of osteoblast differentiation GO:0045669 34 0.031
small molecule biosynthetic process GO:0044283 132 0.031
single organism nuclear import GO:1902593 95 0.031
negative regulation of protein modification process GO:0031400 163 0.031
extracellular matrix organization GO:0030198 147 0.031
cranial nerve development GO:0021545 41 0.030
regulation of carbohydrate metabolic process GO:0006109 75 0.030
mesenchymal cell proliferation GO:0010463 44 0.030
biomineral tissue development GO:0031214 64 0.030
jnk cascade GO:0007254 72 0.030
cellular metal ion homeostasis GO:0006875 151 0.030
organelle localization GO:0051640 179 0.030
cerebellar cortex development GO:0021695 48 0.030
amino acid transmembrane transport GO:0003333 37 0.030
protein catabolic process GO:0030163 221 0.030
male gamete generation GO:0048232 285 0.030
Mouse
glycerolipid metabolic process GO:0046486 122 0.030
fatty acid metabolic process GO:0006631 121 0.030
protein localization to organelle GO:0033365 185 0.030
negative regulation of prostatic bud formation GO:0060686 4 0.030
muscle system process GO:0003012 141 0.030
male gonad development GO:0008584 88 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
myeloid cell differentiation GO:0030099 233 0.029
cell growth GO:0016049 130 0.029
b cell activation GO:0042113 161 0.029
cellular amide metabolic process GO:0043603 58 0.029
Human Mouse Rat
organic acid biosynthetic process GO:0016053 86 0.029
regulation of hormone secretion GO:0046883 88 0.029
gliogenesis GO:0042063 141 0.029
positive regulation of kinase activity GO:0033674 155 0.029
peptide hormone secretion GO:0030072 109 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.029
negative regulation of growth GO:0045926 99 0.029
hematopoietic progenitor cell differentiation GO:0002244 143 0.028
regulation of cell growth GO:0001558 91 0.028
pyruvate metabolic process GO:0006090 28 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
mesodermal cell migration GO:0008078 4 0.028
glucose homeostasis GO:0042593 128 0.028
determination of left right symmetry GO:0007368 80 0.028
cardiac septum morphogenesis GO:0060411 46 0.028
negative regulation of mitotic cell cycle embryonic GO:0045976 2 0.028
negative regulation of nervous system development GO:0051961 156 0.028
axial mesodermal cell fate commitment GO:0048322 1 0.028
multicellular organismal signaling GO:0035637 91 0.028
central nervous system neuron differentiation GO:0021953 162 0.028
midbrain development GO:0030901 35 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
regulation of transferase activity GO:0051338 263 0.028
regulation of map kinase activity GO:0043405 120 0.027
cerebellar granule cell precursor proliferation GO:0021930 10 0.027
tissue homeostasis GO:0001894 115 0.027
positive regulation of cell motility GO:2000147 116 0.027
insulin metabolic process GO:1901142 3 0.027
embryonic heart tube development GO:0035050 65 0.027
sterol homeostasis GO:0055092 45 0.027
hexose biosynthetic process GO:0019319 39 0.027
adult behavior GO:0030534 135 0.027
nuclear transport GO:0051169 139 0.027
cellular response to organonitrogen compound GO:0071417 145 0.026
purine containing compound catabolic process GO:0072523 213 0.026
response to light stimulus GO:0009416 135 0.026
organ growth GO:0035265 117 0.026
cardiac chamber development GO:0003205 108 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.026
epithelial cell morphogenesis GO:0003382 41 0.026
cellular glucan metabolic process GO:0006073 32 0.026
axon ensheathment GO:0008366 76 0.026
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.026
regulation of transmembrane transport GO:0034762 128 0.026
positive regulation of proteolysis GO:0045862 85 0.026
cell proliferation in external granule layer GO:0021924 10 0.026
forebrain regionalization GO:0021871 25 0.026
regulation of lipid metabolic process GO:0019216 118 0.026
regulation of organelle organization GO:0033043 289 0.026
small molecule catabolic process GO:0044282 71 0.026
aromatic compound catabolic process GO:0019439 286 0.026
neutral lipid metabolic process GO:0006638 57 0.026
detection of external stimulus GO:0009581 61 0.026
midgut development GO:0007494 4 0.025
myelination GO:0042552 74 0.025
mesoderm development GO:0007498 100 0.025
lymphocyte differentiation GO:0030098 242 0.025
insulin processing GO:0030070 2 0.025
multicellular organism growth GO:0035264 161 0.025
male genitalia morphogenesis GO:0048808 4 0.025
negative regulation of neuron death GO:1901215 98 0.025
regulation of bmp signaling pathway GO:0030510 60 0.025
response to sterol GO:0036314 4 0.025
small gtpase mediated signal transduction GO:0007264 97 0.025
transmission of nerve impulse GO:0019226 76 0.025
cofactor metabolic process GO:0051186 80 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
hippocampus development GO:0021766 52 0.025
regulation of synaptic plasticity GO:0048167 87 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
glial cell differentiation GO:0010001 131 0.025
embryonic heart tube morphogenesis GO:0003143 51 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.025
embryonic appendage morphogenesis GO:0035113 126 0.025
t cell differentiation GO:0030217 174 0.025
molting cycle GO:0042303 90 0.025
regulation of axon extension GO:0030516 43 0.024
determination of heart left right asymmetry GO:0061371 48 0.024
norepinephrine transport GO:0015874 2 0.024
fat soluble vitamin biosynthetic process GO:0042362 4 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
eye photoreceptor cell differentiation GO:0001754 41 0.024
positive regulation of cell migration GO:0030335 109 0.024
platelet activation GO:0030168 40 0.024
lipid transport GO:0006869 98 0.024
actin filament based movement GO:0030048 23 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
cellular response to hormone stimulus GO:0032870 150 0.024
gtp metabolic process GO:0046039 144 0.024
dendrite development GO:0016358 115 0.024
neuroblast proliferation GO:0007405 49 0.024
regulation of neuron death GO:1901214 134 0.024
negative regulation of proteolysis GO:0045861 74 0.024
rap protein signal transduction GO:0032486 3 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.023
regulation of stress activated mapk cascade GO:0032872 69 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
positive regulation of stem cell proliferation GO:2000648 59 0.023
cerebellum vasculature development GO:0061300 1 0.023
sensory perception of chemical stimulus GO:0007606 51 0.023
regulation of intracellular transport GO:0032386 159 0.023
positive regulation of wnt signaling pathway GO:0030177 45 0.023
regulation of defense response GO:0031347 233 0.023
rho protein signal transduction GO:0007266 32 0.023
glucose metabolic process GO:0006006 92 0.023
muscle tissue morphogenesis GO:0060415 53 0.023
regulation of peptide hormone secretion GO:0090276 75 0.023
blood circulation GO:0008015 195 0.023
mammary gland morphogenesis GO:0060443 54 0.023
peptidyl tyrosine modification GO:0018212 145 0.023
regulation of muscle tissue development GO:1901861 97 0.023
regulation of timing of cell differentiation GO:0048505 11 0.023
microtubule cytoskeleton organization GO:0000226 157 0.023
regulation of fat cell differentiation GO:0045598 81 0.023
dorsal ventral axon guidance GO:0033563 3 0.023
ureteric bud development GO:0001657 94 0.022
immune effector process GO:0002252 321 0.022
mesoderm formation GO:0001707 62 0.022
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.022
peptide metabolic process GO:0006518 46 0.022
Human Mouse Rat
norepinephrine secretion GO:0048243 2 0.022
regulation of protein processing GO:0070613 96 0.022
peripheral nervous system development GO:0007422 53 0.022
renal sodium ion transport GO:0003096 2 0.022
purine nucleoside catabolic process GO:0006152 205 0.022
regulation of epithelial cell proliferation GO:0050678 141 0.022
positive regulation of glycolytic process GO:0045821 4 0.022
negative regulation of epithelial cell proliferation GO:0050680 64 0.022
muscle contraction GO:0006936 101 0.022
forebrain generation of neurons GO:0021872 63 0.022
nerve development GO:0021675 67 0.022
regulation of cellular protein catabolic process GO:1903362 61 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.022
response to inorganic substance GO:0010035 96 0.021
peptidyl amino acid modification GO:0018193 336 0.021
cellular response to biotic stimulus GO:0071216 92 0.021
positive regulation of ossification GO:0045778 47 0.021
inner ear morphogenesis GO:0042472 101 0.021
regulation of protein localization GO:0032880 231 0.021
heterocycle catabolic process GO:0046700 280 0.021
polarity specification of proximal distal axis GO:0010085 2 0.021
positive regulation of homeostatic process GO:0032846 64 0.021
salivary gland morphogenesis GO:0007435 33 0.021
synapse organization GO:0050808 125 0.021
embryonic placenta development GO:0001892 98 0.021
positive regulation of reproductive process GO:2000243 19 0.021
sensory system development GO:0048880 3 0.021
cerebellum morphogenesis GO:0021587 42 0.021
cardiac muscle tissue development GO:0048738 130 0.021
monosaccharide metabolic process GO:0005996 106 0.021
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.021
regulation of t cell activation GO:0050863 170 0.021
post anal tail morphogenesis GO:0036342 23 0.021
negative regulation of ossification GO:0030279 49 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
gonad morphogenesis GO:0035262 1 0.021
heart contraction GO:0060047 93 0.020
negative regulation of protein processing GO:0010955 79 0.020
cardiac muscle cell contraction GO:0086003 7 0.020
lipid homeostasis GO:0055088 63 0.020
branching involved in salivary gland morphogenesis GO:0060445 26 0.020
somitogenesis GO:0001756 69 0.020
regulation of cell motility GO:2000145 236 0.020
female gamete generation GO:0007292 74 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
kidney mesenchyme morphogenesis GO:0072131 4 0.020
muscle hypertrophy GO:0014896 24 0.020

Pcsk6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.041
inherited metabolic disorder DOID:655 0 0.038
disease of anatomical entity DOID:7 0 0.035
cardiovascular system disease DOID:1287 0 0.035
musculoskeletal system disease DOID:17 0 0.032
heart disease DOID:114 0 0.032
nervous system disease DOID:863 0 0.023