Mus musculus

0 known processes

Lmnb2

lamin B2

Lmnb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear envelope organization GO:0006998 11 0.665
Mouse Fly
cellular response to sterol depletion GO:0071501 4 0.444
Mouse
myosin filament assembly GO:0031034 2 0.395
Worm
lateral inhibition GO:0046331 1 0.357
Fly
localization within membrane GO:0051668 4 0.329
Worm Fly
srebp signaling pathway GO:0032933 4 0.289
Mouse
myosin filament organization GO:0031033 3 0.266
Worm
cellular component assembly involved in morphogenesis GO:0010927 139 0.266
Worm
protein localization to nuclear envelope GO:0090435 2 0.243
Fly
release of cytochrome c from mitochondria GO:0001836 23 0.240
Mouse
gene silencing GO:0016458 38 0.188
Fly
meiotic nuclear division GO:0007126 115 0.175
Worm
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.170
Mouse
meiotic cell cycle GO:0051321 122 0.165
Worm
apoptotic mitochondrial changes GO:0008637 48 0.160
Mouse
actin filament polymerization GO:0030041 44 0.158
Fly
endocytosis GO:0006897 168 0.155
Worm
single organism nuclear import GO:1902593 95 0.155
Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.151
Mouse
cytoplasmic transport GO:0016482 234 0.150
Mouse
apoptotic signaling pathway GO:0097190 306 0.135
Mouse
protein localization to organelle GO:0033365 185 0.135
Mouse Fly
nuclear transport GO:0051169 139 0.134
Mouse
establishment of organelle localization GO:0051656 122 0.133
Fly
actin polymerization or depolymerization GO:0008154 54 0.129
Fly
cellular amino acid metabolic process GO:0006520 103 0.129
cellular protein complex assembly GO:0043623 116 0.120
Worm Fly
intracellular protein transport GO:0006886 204 0.117
Mouse
establishment of protein localization to organelle GO:0072594 118 0.116
Mouse
heterocycle catabolic process GO:0046700 280 0.114
microtubule organizing center organization GO:0031023 28 0.112
Fly
regulation of protein localization GO:0032880 231 0.112
Mouse
membrane organization GO:0061024 245 0.107
Mouse Fly
endomembrane system organization GO:0010256 147 0.104
Mouse Fly
regulation of actin filament polymerization GO:0030833 38 0.103
Fly
regulation of cytoskeleton organization GO:0051493 122 0.102
Fly
dna metabolic process GO:0006259 303 0.101
regulation of apoptotic signaling pathway GO:2001233 197 0.100
Mouse
nuclear import GO:0051170 95 0.100
Mouse
regulation of anatomical structure size GO:0090066 178 0.100
Fly
organonitrogen compound catabolic process GO:1901565 264 0.097
nucleus localization GO:0051647 20 0.097
Fly
regulation of actin polymerization or depolymerization GO:0008064 45 0.097
Fly
protein import into nucleus GO:0006606 95 0.096
Mouse
male gamete generation GO:0048232 285 0.095
Fly
negative regulation of apoptotic signaling pathway GO:2001234 104 0.094
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.094
locomotory behavior GO:0007626 195 0.094
Fly
chromosome segregation GO:0007059 48 0.093
Worm
cell fate commitment GO:0045165 210 0.091
Fly
organic cyclic compound catabolic process GO:1901361 295 0.091
spermatogenesis GO:0007283 284 0.090
Fly
protein import GO:0017038 101 0.090
Mouse
microtubule based process GO:0007017 236 0.089
Mouse Fly
adult locomotory behavior GO:0008344 91 0.086
Fly
regulation of cellular component size GO:0032535 121 0.086
Fly
chromatin organization GO:0006325 206 0.084
Fly
purine nucleoside catabolic process GO:0006152 205 0.081
regulation of actin filament length GO:0030832 45 0.080
Fly
cell cell signaling involved in cell fate commitment GO:0045168 35 0.077
Fly
regulation of actin cytoskeleton organization GO:0032956 84 0.076
Fly
nucleoside phosphate catabolic process GO:1901292 222 0.073
regulation of actin filament based process GO:0032970 99 0.071
Fly
establishment or maintenance of cell polarity GO:0007163 86 0.069
Mouse
regulation of cell motility GO:2000145 236 0.067
Mouse
purine containing compound metabolic process GO:0072521 311 0.064
extrinsic apoptotic signaling pathway GO:0097191 126 0.063
Mouse
organelle localization GO:0051640 179 0.062
Fly
regulation of cell cycle GO:0051726 281 0.062
Worm
nucleoside catabolic process GO:0009164 206 0.061
organelle assembly GO:0070925 177 0.060
Worm
receptor mediated endocytosis GO:0006898 51 0.059
Worm
striated muscle tissue development GO:0014706 293 0.059
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.059
muscle tissue development GO:0060537 308 0.058
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.057
aromatic compound catabolic process GO:0019439 286 0.057
regulation of cellular amine metabolic process GO:0033238 20 0.056
nucleotide metabolic process GO:0009117 332 0.056
macromolecule catabolic process GO:0009057 281 0.056
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.055
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.054
Mouse
muscle cell differentiation GO:0042692 261 0.053
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 66 0.053
er nucleus signaling pathway GO:0006984 27 0.053
Mouse
multicellular organism growth GO:0035264 161 0.051
Worm
nucleus organization GO:0006997 45 0.051
Mouse Worm Fly
connective tissue development GO:0061448 179 0.050
Fly
regulation of protein localization to nucleus GO:1900180 60 0.050
Mouse
gtp catabolic process GO:0006184 143 0.050
protein catabolic process GO:0030163 221 0.050
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.049
protein polymerization GO:0051258 57 0.049
Fly
striated muscle cell development GO:0055002 125 0.049
Mouse Worm
meiotic cell cycle process GO:1903046 77 0.049
digestive system development GO:0055123 200 0.049
Fly
ribonucleoside catabolic process GO:0042454 206 0.048
ribose phosphate metabolic process GO:0019693 291 0.048
regulation of cell migration GO:0030334 219 0.048
Mouse
organophosphate catabolic process GO:0046434 232 0.048
digestive tract morphogenesis GO:0048546 147 0.048
Fly
cell cycle arrest GO:0007050 37 0.047
Worm
carbohydrate derivative catabolic process GO:1901136 231 0.047
germ cell development GO:0007281 185 0.047
Worm
muscle cell development GO:0055001 133 0.046
Mouse Worm
peptidyl amino acid modification GO:0018193 336 0.046
gonad development GO:0008406 141 0.046
Worm Fly
ribonucleoside triphosphate metabolic process GO:0009199 220 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.045
purine nucleoside triphosphate metabolic process GO:0009144 226 0.045
maintenance of location GO:0051235 89 0.045
glycosyl compound metabolic process GO:1901657 246 0.044
regulation of protein kinase activity GO:0045859 232 0.044
purine nucleoside metabolic process GO:0042278 241 0.043
cell type specific apoptotic process GO:0097285 268 0.043
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.042
regulation of transferase activity GO:0051338 263 0.042
purine nucleotide catabolic process GO:0006195 211 0.042
ribonucleotide catabolic process GO:0009261 208 0.041
chromatin silencing GO:0006342 15 0.041
Fly
ribonucleoside triphosphate catabolic process GO:0009203 199 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
development of primary sexual characteristics GO:0045137 143 0.039
Worm Fly
regulation of protein complex assembly GO:0043254 83 0.039
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
ventricular cardiac muscle cell differentiation GO:0055012 17 0.038
Mouse
cellular amine metabolic process GO:0044106 44 0.038
protein targeting GO:0006605 143 0.038
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
purine containing compound catabolic process GO:0072523 213 0.037
amine metabolic process GO:0009308 45 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
nuclear division GO:0000280 158 0.037
Worm
cardiac muscle cell development GO:0055013 39 0.037
Mouse
dna endoreduplication GO:0042023 4 0.036
actin cytoskeleton organization GO:0030036 220 0.036
Worm Fly
regulation of kinase activity GO:0043549 249 0.036
regulation of cellular catabolic process GO:0031329 242 0.035
regulation of organelle organization GO:0033043 289 0.035
Mouse Fly
guanosine containing compound metabolic process GO:1901068 144 0.034
mitotic cell cycle process GO:1903047 159 0.034
Worm Fly
meiosis i GO:0007127 60 0.034
ventricular cardiac muscle cell development GO:0055015 11 0.034
Mouse
centrosome organization GO:0051297 26 0.033
Fly
regulation of intracellular transport GO:0032386 159 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
Mouse
organelle fission GO:0048285 170 0.032
Worm
purine nucleotide metabolic process GO:0006163 302 0.032
positive regulation of growth GO:0045927 104 0.032
Worm
nucleoside phosphate metabolic process GO:0006753 338 0.031
epithelial tube formation GO:0072175 130 0.031
nucleoside metabolic process GO:0009116 246 0.031
cellular ketone metabolic process GO:0042180 84 0.031
regulation of multi organism process GO:0043900 111 0.030
digestive tract development GO:0048565 190 0.030
Fly
negative regulation of cell cycle GO:0045786 123 0.030
Worm
regulation of protein transport GO:0051223 163 0.030
regulation of cytoplasmic transport GO:1903649 112 0.029
cell aging GO:0007569 35 0.029
Fly
negative regulation of molecular function GO:0044092 258 0.028
purine ribonucleoside catabolic process GO:0046130 205 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
positive regulation of cell death GO:0010942 224 0.028
regulation of cell cycle process GO:0010564 160 0.028
cardiac cell development GO:0055006 41 0.028
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
muscle tissue morphogenesis GO:0060415 53 0.027
Fly
transmembrane transport GO:0055085 412 0.027
microtubule cytoskeleton organization GO:0000226 157 0.027
Mouse Fly
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
positive regulation of programmed cell death GO:0043068 218 0.026
positive regulation of cell cycle GO:0045787 92 0.026
regulation of establishment of protein localization GO:0070201 181 0.026
negative regulation of organelle organization GO:0010639 90 0.025
Mouse
negative regulation of protein modification process GO:0031400 163 0.025
myofibril assembly GO:0030239 34 0.025
Worm
fertilization GO:0009566 127 0.025
cell adhesion GO:0007155 329 0.024
mapk cascade GO:0000165 281 0.024
regulation of ras gtpase activity GO:0032318 88 0.024
rna processing GO:0006396 105 0.024
protein complex localization GO:0031503 19 0.024
Worm Fly
protein localization to nucleus GO:0034504 121 0.023
Mouse Fly
regulation of cellular response to stress GO:0080135 159 0.023
positive regulation of protein modification process GO:0031401 299 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
protein processing GO:0016485 163 0.023
positive regulation of organelle organization GO:0010638 128 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.023
cardiac muscle tissue development GO:0048738 130 0.023
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.023
Worm
ribonucleoside metabolic process GO:0009119 245 0.022
gtp metabolic process GO:0046039 144 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
mitotic cell cycle GO:0000278 195 0.022
Worm Fly
positive regulation of protein phosphorylation GO:0001934 242 0.022
camera type eye development GO:0043010 266 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
response to organic cyclic compound GO:0014070 198 0.022
phagocytosis GO:0006909 66 0.021
regulation of neuron differentiation GO:0045664 281 0.021
nucleotide catabolic process GO:0009166 217 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
cation transport GO:0006812 399 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
multi organism reproductive behavior GO:0044705 29 0.021
Worm
cellularization GO:0007349 1 0.020
tendon development GO:0035989 6 0.020
Fly
positive regulation of protein kinase activity GO:0045860 144 0.020
single fertilization GO:0007338 82 0.020
regulation of homeostatic process GO:0032844 182 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
embryonic epithelial tube formation GO:0001838 130 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
negative regulation of phosphate metabolic process GO:0045936 184 0.019
homeostasis of number of cells GO:0048872 210 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.019
reproductive behavior GO:0019098 32 0.019
Worm
positive regulation of proteolysis GO:0045862 85 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
skeletal system development GO:0001501 356 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
Mouse
ossification GO:0001503 216 0.019
multicellular organismal reproductive behavior GO:0033057 23 0.018
Worm
response to organonitrogen compound GO:0010243 246 0.018
regulation of secretion GO:0051046 274 0.018
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.018
Mouse
regulation of protein import into nucleus GO:0042306 52 0.018
cellular homeostasis GO:0019725 240 0.018
multi organism behavior GO:0051705 62 0.018
Worm
regulation of intracellular protein transport GO:0033157 82 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
ras protein signal transduction GO:0007265 77 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
regulation of binding GO:0051098 111 0.018
carbohydrate metabolic process GO:0005975 230 0.018
divalent metal ion transport GO:0070838 172 0.017
oxidation reduction process GO:0055114 342 0.017
cytokine production GO:0001816 319 0.017
rho protein signal transduction GO:0007266 32 0.017
cardiac muscle cell differentiation GO:0055007 69 0.017
Mouse
oocyte construction GO:0007308 2 0.017
regulation of ion transport GO:0043269 215 0.017
gland development GO:0048732 330 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.017
positive regulation of apoptotic process GO:0043065 217 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
female gamete generation GO:0007292 74 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
mitotic cytokinesis GO:0000281 4 0.016
dna biosynthetic process GO:0071897 22 0.016
response to inorganic substance GO:0010035 96 0.016
leukocyte proliferation GO:0070661 172 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
forebrain development GO:0030900 302 0.016
neural tube development GO:0021915 160 0.016
mitochondrion organization GO:0007005 134 0.015
Mouse
regulation of cytokine production GO:0001817 266 0.015
sensory perception GO:0007600 245 0.015
blood circulation GO:0008015 195 0.015
circulatory system process GO:0003013 197 0.015
immune effector process GO:0002252 321 0.015
positive regulation of nervous system development GO:0051962 221 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
regulation of cell division GO:0051302 76 0.015
rhythmic process GO:0048511 174 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
regulation of protein targeting GO:1903533 61 0.015
regulation of mapk cascade GO:0043408 248 0.015
male meiosis GO:0007140 37 0.015
stem cell differentiation GO:0048863 268 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
Fly
rna interference GO:0016246 2 0.014
regulation of proteolysis GO:0030162 164 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
dendrite development GO:0016358 115 0.014
intracellular mrna localization GO:0008298 4 0.014
response to light stimulus GO:0009416 135 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of cell projection organization GO:0031344 206 0.014
response to growth factor GO:0070848 198 0.014
regulation of gtp catabolic process GO:0033124 113 0.014
actin filament organization GO:0007015 113 0.014
Fly
regulation of nucleocytoplasmic transport GO:0046822 73 0.014
body morphogenesis GO:0010171 45 0.014
Worm
ion transmembrane transport GO:0034220 361 0.014
response to lipopolysaccharide GO:0032496 128 0.014
primary neural tube formation GO:0014020 95 0.014
sensory organ morphogenesis GO:0090596 242 0.014
Fly
divalent inorganic cation transport GO:0072511 178 0.014
mrna processing GO:0006397 63 0.014
regulation of hydrolase activity GO:0051336 246 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
leukocyte differentiation GO:0002521 342 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
positive regulation of chromosome segregation GO:0051984 4 0.013
response to peptide GO:1901652 136 0.013
calcium ion transport GO:0006816 159 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
genitalia development GO:0048806 37 0.013
Worm
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.013
neuron apoptotic process GO:0051402 142 0.013
multicellular organismal aging GO:0010259 24 0.013
Worm
regulation of secretion by cell GO:1903530 249 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
chemotaxis GO:0006935 247 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
dna recombination GO:0006310 92 0.013
negative regulation of intracellular transport GO:0032387 38 0.013
regulation of t cell proliferation GO:0042129 92 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
lymphocyte differentiation GO:0030098 242 0.013
nitrogen compound transport GO:0071705 271 0.012
regulation of defense response GO:0031347 233 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
astral microtubule organization GO:0030953 3 0.012
t cell activation GO:0042110 289 0.012
protein maturation GO:0051604 176 0.012
small molecule biosynthetic process GO:0044283 132 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
anatomical structure homeostasis GO:0060249 145 0.012
cell activation involved in immune response GO:0002263 126 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
exocytosis GO:0006887 121 0.012
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 9 0.012
single organism cell adhesion GO:0098602 156 0.012
extracellular structure organization GO:0043062 148 0.012
negative regulation of neuron death GO:1901215 98 0.012
metal ion homeostasis GO:0055065 189 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
negative regulation of cell development GO:0010721 169 0.012
retina development in camera type eye GO:0060041 119 0.012
leukocyte mediated immunity GO:0002443 174 0.012
centrosome duplication GO:0051298 16 0.012
b cell activation GO:0042113 161 0.012
cation homeostasis GO:0055080 212 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
dna integrity checkpoint GO:0031570 28 0.011
response to insulin GO:0032868 100 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
cytokinetic process GO:0032506 2 0.011
protein localization to membrane GO:0072657 108 0.011
organism emergence from protective structure GO:0071684 4 0.011
blood vessel morphogenesis GO:0048514 285 0.011
negative regulation of kinase activity GO:0033673 81 0.011
lymphocyte proliferation GO:0046651 164 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
rna splicing via transesterification reactions GO:0000375 43 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of metal ion transport GO:0010959 106 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
cellular chemical homeostasis GO:0055082 215 0.011
double strand break repair GO:0006302 48 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
peptidyl serine modification GO:0018209 83 0.010
microtubule nucleation GO:0007020 2 0.010
cellular response to oxidative stress GO:0034599 76 0.010
glycoprotein metabolic process GO:0009100 116 0.010
mrna metabolic process GO:0016071 84 0.010
mitotic nuclear division GO:0007067 48 0.010
Worm
anion transport GO:0006820 177 0.010
cognition GO:0050890 149 0.010
response to oxidative stress GO:0006979 123 0.010
membrane disassembly GO:0030397 1 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
negative regulation of mitotic cell cycle GO:0045930 58 0.010
neuron death GO:0070997 154 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
pole plasm assembly GO:0007315 2 0.010
peptidyl threonine phosphorylation GO:0018107 31 0.010
atp catabolic process GO:0006200 55 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
meiotic chromosome segregation GO:0045132 19 0.010
axonogenesis GO:0007409 274 0.010
protein oligomerization GO:0051259 67 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
blastocyst development GO:0001824 80 0.010
oocyte axis specification GO:0007309 2 0.010
neuron migration GO:0001764 122 0.010
negative regulation of protein processing GO:0010955 79 0.010

Lmnb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
gastrointestinal system cancer DOID:3119 0 0.012
organ system cancer DOID:0050686 0 0.012