Mus musculus

0 known processes

Tha1

threonine aldolase 1

(Aliases: 1300017K07Rik,GLY1)

Tha1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.106
oxidation reduction process GO:0055114 342 0.067
ion transmembrane transport GO:0034220 361 0.059
anion transport GO:0006820 177 0.059
cation transmembrane transport GO:0098655 266 0.059
cellular amino acid metabolic process GO:0006520 103 0.054
cation transport GO:0006812 399 0.052
cellular ketone metabolic process GO:0042180 84 0.051
organic cyclic compound catabolic process GO:1901361 295 0.051
cellular amine metabolic process GO:0044106 44 0.051
immune effector process GO:0002252 321 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
cellular response to lipid GO:0071396 145 0.043
cellular homeostasis GO:0019725 240 0.040
apoptotic signaling pathway GO:0097190 306 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
regulation of cytokine production GO:0001817 266 0.038
cytokine production GO:0001816 319 0.037
nitrogen compound transport GO:0071705 271 0.037
rhythmic process GO:0048511 174 0.036
nucleoside phosphate metabolic process GO:0006753 338 0.035
cellular metal ion homeostasis GO:0006875 151 0.035
purine containing compound metabolic process GO:0072521 311 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
connective tissue development GO:0061448 179 0.035
organonitrogen compound catabolic process GO:1901565 264 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.034
skeletal system development GO:0001501 356 0.034
digestive tract development GO:0048565 190 0.034
regulation of hormone levels GO:0010817 211 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
negative regulation of cell proliferation GO:0008285 296 0.033
digestive system development GO:0055123 200 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
aromatic compound catabolic process GO:0019439 286 0.033
embryonic organ morphogenesis GO:0048562 276 0.032
gland development GO:0048732 330 0.032
negative regulation of immune system process GO:0002683 209 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.031
cation homeostasis GO:0055080 212 0.031
nucleotide metabolic process GO:0009117 332 0.031
amine metabolic process GO:0009308 45 0.031
cellular ion homeostasis GO:0006873 165 0.030
placenta development GO:0001890 140 0.030
regulation of defense response GO:0031347 233 0.029
heterocycle catabolic process GO:0046700 280 0.029
muscle tissue development GO:0060537 308 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.029
anion transmembrane transport GO:0098656 71 0.028
response to lipopolysaccharide GO:0032496 128 0.028
regulation of cell cycle GO:0051726 281 0.028
locomotory behavior GO:0007626 195 0.028
cellular lipid metabolic process GO:0044255 323 0.028
cellular response to hormone stimulus GO:0032870 150 0.028
cellular response to dna damage stimulus GO:0006974 207 0.028
regionalization GO:0003002 337 0.027
nucleoside catabolic process GO:0009164 206 0.027
cell type specific apoptotic process GO:0097285 268 0.027
negative regulation of cytokine production GO:0001818 84 0.027
organic acid transport GO:0015849 101 0.027
organic anion transport GO:0015711 137 0.027
dna metabolic process GO:0006259 303 0.027
negative regulation of molecular function GO:0044092 258 0.026
positive regulation of apoptotic process GO:0043065 217 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
response to organic cyclic compound GO:0014070 198 0.025
t cell activation GO:0042110 289 0.025
regulation of secretion GO:0051046 274 0.025
renal system development GO:0072001 225 0.024
compound eye development GO:0048749 1 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
homeostasis of number of cells GO:0048872 210 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
inorganic ion transmembrane transport GO:0098660 234 0.024
ribonucleoside catabolic process GO:0042454 206 0.023
cellular response to growth factor stimulus GO:0071363 197 0.023
stem cell differentiation GO:0048863 268 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
response to organonitrogen compound GO:0010243 246 0.023
carboxylic acid transport GO:0046942 100 0.023
regulation of organ morphogenesis GO:2000027 144 0.023
sensory organ morphogenesis GO:0090596 242 0.023
blood vessel morphogenesis GO:0048514 285 0.022
neuron apoptotic process GO:0051402 142 0.022
peptidyl amino acid modification GO:0018193 336 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
circadian rhythm GO:0007623 114 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.021
regulation of cell activation GO:0050865 289 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
cofactor metabolic process GO:0051186 80 0.021
regulation of leukocyte differentiation GO:1902105 159 0.021
cellular chemical homeostasis GO:0055082 215 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
chromatin modification GO:0016568 187 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
peptide transport GO:0015833 133 0.021
positive regulation of cytokine production GO:0001819 174 0.021
morphogenesis of a branching epithelium GO:0061138 193 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
digestive tract morphogenesis GO:0048546 147 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
dephosphorylation GO:0016311 129 0.020
positive regulation of cell death GO:0010942 224 0.020
amide transport GO:0042886 138 0.020
ras protein signal transduction GO:0007265 77 0.020
chromatin organization GO:0006325 206 0.020
regulation of homeostatic process GO:0032844 182 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
small molecule biosynthetic process GO:0044283 132 0.020
embryonic placenta development GO:0001892 98 0.019
histone modification GO:0016570 159 0.019
nucleotide catabolic process GO:0009166 217 0.019
muscle cell differentiation GO:0042692 261 0.019
maintenance of location GO:0051235 89 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
regulation of secretion by cell GO:1903530 249 0.019
metal ion homeostasis GO:0055065 189 0.019
cell adhesion GO:0007155 329 0.019
striated muscle tissue development GO:0014706 293 0.019
epithelial cell proliferation GO:0050673 174 0.019
hexose metabolic process GO:0019318 98 0.019
camera type eye development GO:0043010 266 0.019
carbohydrate metabolic process GO:0005975 230 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
regulation of neuron differentiation GO:0045664 281 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.018
regulation of organelle organization GO:0033043 289 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
covalent chromatin modification GO:0016569 163 0.018
respiratory system development GO:0060541 190 0.018
regulation of system process GO:0044057 200 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
protein catabolic process GO:0030163 221 0.018
urogenital system development GO:0001655 261 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
nucleoside metabolic process GO:0009116 246 0.018
peptide secretion GO:0002790 114 0.018
ossification GO:0001503 216 0.018
skeletal system morphogenesis GO:0048705 203 0.018
inflammatory response GO:0006954 244 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
myeloid leukocyte differentiation GO:0002573 119 0.017
glucose homeostasis GO:0042593 128 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
adaptive immune response GO:0002250 155 0.017
macromolecule catabolic process GO:0009057 281 0.017
myeloid cell differentiation GO:0030099 233 0.017
cartilage development GO:0051216 140 0.017
carboxylic acid biosynthetic process GO:0046394 86 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
cellular modified amino acid metabolic process GO:0006575 63 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
defense response to other organism GO:0098542 197 0.017
small molecule catabolic process GO:0044282 71 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
lymphocyte differentiation GO:0030098 242 0.016
cell fate commitment GO:0045165 210 0.016
lipid localization GO:0010876 126 0.016
ovarian follicle development GO:0001541 40 0.016
alpha beta t cell activation GO:0046631 91 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
sensory perception GO:0007600 245 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
coenzyme metabolic process GO:0006732 52 0.016
male sex differentiation GO:0046661 109 0.016
positive regulation of nervous system development GO:0051962 221 0.016
alpha beta t cell differentiation GO:0046632 69 0.016
monosaccharide metabolic process GO:0005996 106 0.016
organic acid biosynthetic process GO:0016053 86 0.016
lymphocyte activation involved in immune response GO:0002285 93 0.016
retina development in camera type eye GO:0060041 119 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
leukocyte differentiation GO:0002521 342 0.016
endomembrane system organization GO:0010256 147 0.016
multicellular organism growth GO:0035264 161 0.016
hormone metabolic process GO:0042445 86 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
angiogenesis GO:0001525 201 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
response to oxygen levels GO:0070482 62 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
purine containing compound catabolic process GO:0072523 213 0.015
positive regulation of cell activation GO:0050867 158 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
response to peptide GO:1901652 136 0.015
kidney development GO:0001822 213 0.015
muscle system process GO:0003012 141 0.015
blood circulation GO:0008015 195 0.015
response to growth factor GO:0070848 198 0.015
positive regulation of defense response GO:0031349 124 0.015
cofactor transport GO:0051181 4 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
calcium ion homeostasis GO:0055074 127 0.015
skeletal muscle organ development GO:0060538 163 0.015
inorganic anion transport GO:0015698 43 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
response to nutrient levels GO:0031667 109 0.015
cell activation involved in immune response GO:0002263 126 0.014
extracellular structure organization GO:0043062 148 0.014
circulatory system process GO:0003013 197 0.014
mitochondrion organization GO:0007005 134 0.014
regulation of feeding behavior GO:0060259 3 0.014
lateral inhibition GO:0046331 1 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
glycoprotein metabolic process GO:0009100 116 0.014
negative regulation of cell development GO:0010721 169 0.014
regulation of membrane potential GO:0042391 192 0.014
regulation of adaptive immune response GO:0002819 90 0.014
regulation of t cell activation GO:0050863 170 0.014
neuron migration GO:0001764 122 0.014
multi multicellular organism process GO:0044706 109 0.014
regulation of protein localization GO:0032880 231 0.014
cell maturation GO:0048469 127 0.014
insulin secretion GO:0030073 89 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.014
positive regulation of protein modification process GO:0031401 299 0.014
cell substrate adhesion GO:0031589 130 0.014
gastrulation GO:0007369 116 0.014
anatomical structure homeostasis GO:0060249 145 0.014
organelle fission GO:0048285 170 0.014
positive regulation of fatty acid oxidation GO:0046321 4 0.014
peptide hormone secretion GO:0030072 109 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
regulation of protein transport GO:0051223 163 0.013
defense response to virus GO:0051607 68 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
neurotransmitter transport GO:0006836 76 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
lipid modification GO:0030258 65 0.013
sulfur compound metabolic process GO:0006790 100 0.013
intracellular protein transport GO:0006886 204 0.013
female sex differentiation GO:0046660 84 0.013
developmental maturation GO:0021700 193 0.013
cellular response to external stimulus GO:0071496 88 0.013
respiratory tube development GO:0030323 167 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.013
telencephalon development GO:0021537 186 0.013
response to peptide hormone GO:0043434 127 0.013
carboxylic acid catabolic process GO:0046395 51 0.013
male anatomical structure morphogenesis GO:0090598 4 0.013
regulation of response to wounding GO:1903034 189 0.013
gonad development GO:0008406 141 0.013
response to extracellular stimulus GO:0009991 127 0.013
muscle contraction GO:0006936 101 0.013
fatty acid metabolic process GO:0006631 121 0.013
cerebral cortex development GO:0021987 86 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of hydrolase activity GO:0051336 246 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
cellular response to cytokine stimulus GO:0071345 189 0.012
mitotic cell cycle GO:0000278 195 0.012
organic acid catabolic process GO:0016054 51 0.012
negative regulation of nervous system development GO:0051961 156 0.012
innate immune response GO:0045087 157 0.012
lipid biosynthetic process GO:0008610 179 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
bone development GO:0060348 120 0.012
spermatogenesis GO:0007283 284 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
stem cell development GO:0048864 219 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
cytokinetic process GO:0032506 2 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
regulation of neuron death GO:1901214 134 0.012
ureteric bud development GO:0001657 94 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
male gonad development GO:0008584 88 0.012
protein localization to organelle GO:0033365 185 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.012
actin filament organization GO:0007015 113 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
activation of immune response GO:0002253 138 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
wnt signaling pathway GO:0016055 188 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
t cell differentiation GO:0030217 174 0.012
embryonic skeletal system development GO:0048706 120 0.012
positive regulation of immune effector process GO:0002699 107 0.012
regulation of inflammatory response GO:0050727 147 0.012
response to acid chemical GO:0001101 111 0.012
neuron death GO:0070997 154 0.012
leukocyte migration GO:0050900 124 0.012
regulation of morphogenesis of a branching structure GO:0060688 53 0.012
organ growth GO:0035265 117 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
action potential GO:0001508 78 0.011
alcohol metabolic process GO:0006066 116 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
lipoprotein metabolic process GO:0042157 43 0.011
membrane organization GO:0061024 245 0.011
nuclear transport GO:0051169 139 0.011
regulation of transmembrane transport GO:0034762 128 0.011
organic hydroxy compound transport GO:0015850 93 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of cell cycle process GO:0010564 160 0.011
nuclear division GO:0000280 158 0.011
regulation of neuron projection development GO:0010975 169 0.011
response to inorganic substance GO:0010035 96 0.011
hormone secretion GO:0046879 128 0.011
protein maturation GO:0051604 176 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
appendage development GO:0048736 166 0.011
liver development GO:0001889 66 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
tube formation GO:0035148 140 0.011
steroid metabolic process GO:0008202 119 0.011
cd4 positive alpha beta t cell activation GO:0035710 45 0.011
cerebellar cortex development GO:0021695 48 0.011
negative regulation of immune effector process GO:0002698 55 0.011
cellular potassium ion transport GO:0071804 43 0.011
organophosphate catabolic process GO:0046434 232 0.011
negative regulation of hormone metabolic process GO:0032351 4 0.011
forebrain development GO:0030900 302 0.011
response to insulin GO:0032868 100 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
regulation of myeloid leukocyte differentiation GO:0002761 58 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
regulation of hormone secretion GO:0046883 88 0.011
fertilization GO:0009566 127 0.011
chemotaxis GO:0006935 247 0.011
limb development GO:0060173 166 0.011
positive regulation of cell development GO:0010720 237 0.011
axonogenesis GO:0007409 274 0.011
wound healing GO:0042060 157 0.010
midgut development GO:0007494 4 0.010
endocrine system development GO:0035270 98 0.010
very long chain fatty acid catabolic process GO:0042760 2 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
divalent metal ion transport GO:0070838 172 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
development of primary sexual characteristics GO:0045137 143 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
cellular protein catabolic process GO:0044257 155 0.010
negative regulation of cell activation GO:0050866 111 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
cellular amino acid catabolic process GO:0009063 25 0.010
plasma membrane organization GO:0007009 90 0.010
negative regulation of neuron apoptotic process GO:0043524 92 0.010
negative regulation of neuron death GO:1901215 98 0.010
epithelial cell development GO:0002064 159 0.010
synaptic transmission GO:0007268 329 0.010
lymphocyte proliferation GO:0046651 164 0.010
interleukin 8 production GO:0032637 4 0.010
potassium ion transmembrane transport GO:0071805 43 0.010
pallium development GO:0021543 120 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
calcium ion transport GO:0006816 159 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
kidney epithelium development GO:0072073 121 0.010
atp metabolic process GO:0046034 75 0.010

Tha1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
nervous system disease DOID:863 0 0.063
central nervous system disease DOID:331 0 0.023
immune system disease DOID:2914 0 0.020
sensory system disease DOID:0050155 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.013
connective tissue disease DOID:65 0 0.011
brain disease DOID:936 0 0.011