Mus musculus

19 known processes

Manba

mannosidase, beta A, lysosomal

(Aliases: Bmn,2410030O07Rik,B930014J03Rik)

Manba biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.124
metal ion homeostasis GO:0055065 189 0.072
sphingolipid metabolic process GO:0006665 45 0.064
ceramide metabolic process GO:0006672 31 0.060
cation homeostasis GO:0055080 212 0.060
lysosome organization GO:0007040 21 0.058
ion transmembrane transport GO:0034220 361 0.056
anion transport GO:0006820 177 0.054
transmembrane transport GO:0055085 412 0.054
cellular amino acid metabolic process GO:0006520 103 0.051
carbohydrate derivative catabolic process GO:1901136 231 0.050
vacuole organization GO:0007033 38 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.045
amine metabolic process GO:0009308 45 0.045
organonitrogen compound catabolic process GO:1901565 264 0.045
oxidation reduction process GO:0055114 342 0.044
organic anion transport GO:0015711 137 0.043
nucleoside phosphate metabolic process GO:0006753 338 0.043
lytic vacuole organization GO:0080171 21 0.043
organic acid transport GO:0015849 101 0.043
cellular ion homeostasis GO:0006873 165 0.043
regulation of membrane potential GO:0042391 192 0.042
cellular amine metabolic process GO:0044106 44 0.040
membrane lipid metabolic process GO:0006643 53 0.039
carbohydrate metabolic process GO:0005975 230 0.039
cation transport GO:0006812 399 0.039
divalent inorganic cation homeostasis GO:0072507 138 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
cellular homeostasis GO:0019725 240 0.038
sensory perception GO:0007600 245 0.037
cellular ketone metabolic process GO:0042180 84 0.036
homeostasis of number of cells GO:0048872 210 0.036
cellular metal ion homeostasis GO:0006875 151 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
cellular divalent inorganic cation homeostasis GO:0072503 127 0.033
membrane organization GO:0061024 245 0.033
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
maintenance of location GO:0051235 89 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
nucleotide metabolic process GO:0009117 332 0.032
calcium ion homeostasis GO:0055074 127 0.032
macromolecule catabolic process GO:0009057 281 0.032
organophosphate biosynthetic process GO:0090407 122 0.031
locomotory behavior GO:0007626 195 0.030
regulation of interleukin 8 production GO:0032677 3 0.029
multicellular organismal homeostasis GO:0048871 164 0.028
endomembrane system organization GO:0010256 147 0.028
cation transmembrane transport GO:0098655 266 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
nitrogen compound transport GO:0071705 271 0.026
sensory perception of sound GO:0007605 97 0.026
regulation of hydrolase activity GO:0051336 246 0.026
cellular chemical homeostasis GO:0055082 215 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.025
plasma membrane organization GO:0007009 90 0.025
male courtship behavior GO:0008049 2 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
apoptotic signaling pathway GO:0097190 306 0.025
purine nucleoside metabolic process GO:0042278 241 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
anatomical structure homeostasis GO:0060249 145 0.025
purine nucleotide metabolic process GO:0006163 302 0.024
carboxylic acid transport GO:0046942 100 0.024
purine containing compound metabolic process GO:0072521 311 0.024
protein catabolic process GO:0030163 221 0.024
cell adhesion GO:0007155 329 0.024
peptidyl amino acid modification GO:0018193 336 0.023
anion transmembrane transport GO:0098656 71 0.023
phospholipid metabolic process GO:0006644 87 0.023
regulation of organelle organization GO:0033043 289 0.023
interleukin 8 production GO:0032637 4 0.023
lipid biosynthetic process GO:0008610 179 0.023
intracellular protein transport GO:0006886 204 0.023
divalent inorganic cation transport GO:0072511 178 0.022
sphingolipid catabolic process GO:0030149 7 0.022
cellular calcium ion homeostasis GO:0006874 119 0.022
dephosphorylation GO:0016311 129 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
regulation of cellular catabolic process GO:0031329 242 0.022
peptide metabolic process GO:0006518 46 0.022
lipid localization GO:0010876 126 0.022
nucleoside catabolic process GO:0009164 206 0.021
membrane lipid biosynthetic process GO:0046467 32 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
tissue homeostasis GO:0001894 115 0.021
fertilization GO:0009566 127 0.021
sphingolipid biosynthetic process GO:0030148 26 0.021
positive regulation of protein modification process GO:0031401 299 0.021
phospholipid biosynthetic process GO:0008654 36 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
heterocycle catabolic process GO:0046700 280 0.020
nucleoside metabolic process GO:0009116 246 0.020
bone remodeling GO:0046849 53 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
striated muscle tissue development GO:0014706 293 0.020
multicellular organismal signaling GO:0035637 91 0.020
cytokine production GO:0001816 319 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
regulation of system process GO:0044057 200 0.019
regulation of cell motility GO:2000145 236 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
ribonucleoside triphosphate catabolic process GO:0009203 199 0.019
protein processing GO:0016485 163 0.019
neuronal action potential GO:0019228 54 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
amino acid transmembrane transport GO:0003333 37 0.019
germ cell development GO:0007281 185 0.019
regulation of cell adhesion GO:0030155 154 0.019
cellular amide metabolic process GO:0043603 58 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
mapk cascade GO:0000165 281 0.019
organophosphate catabolic process GO:0046434 232 0.018
sequestering of metal ion GO:0051238 19 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
adult behavior GO:0030534 135 0.018
ras protein signal transduction GO:0007265 77 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
male gamete generation GO:0048232 285 0.018
skeletal system development GO:0001501 356 0.018
tissue remodeling GO:0048771 102 0.018
muscle cell differentiation GO:0042692 261 0.018
divalent metal ion transport GO:0070838 172 0.018
nucleotide catabolic process GO:0009166 217 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
aromatic compound catabolic process GO:0019439 286 0.017
regulation of mapk cascade GO:0043408 248 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
neuromuscular process GO:0050905 99 0.017
adult locomotory behavior GO:0008344 91 0.017
amino acid transport GO:0006865 61 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
ossification GO:0001503 216 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
muscle cell development GO:0055001 133 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
purine nucleoside triphosphate metabolic process GO:0009144 226 0.016
learning or memory GO:0007611 148 0.016
regulation of peptidase activity GO:0052547 96 0.016
lipid transport GO:0006869 98 0.016
cell type specific apoptotic process GO:0097285 268 0.016
actin cytoskeleton organization GO:0030036 220 0.016
muscle tissue development GO:0060537 308 0.016
regulation of cytokine production GO:0001817 266 0.016
glycoprotein metabolic process GO:0009100 116 0.016
respiratory tube development GO:0030323 167 0.016
protein maturation GO:0051604 176 0.016
single fertilization GO:0007338 82 0.016
leukocyte mediated immunity GO:0002443 174 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
chemotaxis GO:0006935 247 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
regulation of anatomical structure size GO:0090066 178 0.015
lung development GO:0030324 164 0.015
negative regulation of molecular function GO:0044092 258 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.015
regulation of ion transport GO:0043269 215 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
cellular protein complex assembly GO:0043623 116 0.015
ceramide biosynthetic process GO:0046513 20 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
inflammatory response GO:0006954 244 0.015
response to light stimulus GO:0009416 135 0.015
regulation of secretion GO:0051046 274 0.015
response to growth factor GO:0070848 198 0.015
cognition GO:0050890 149 0.015
glycosaminoglycan metabolic process GO:0030203 34 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
atp metabolic process GO:0046034 75 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
myelination GO:0042552 74 0.014
regulation of proteolysis GO:0030162 164 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
purine containing compound catabolic process GO:0072523 213 0.014
cytoplasmic transport GO:0016482 234 0.014
positive regulation of cell death GO:0010942 224 0.014
regulation of transferase activity GO:0051338 263 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
urogenital system development GO:0001655 261 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
cytokinetic process GO:0032506 2 0.014
cellular response to lipid GO:0071396 145 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
endocytosis GO:0006897 168 0.014
cellular lipid catabolic process GO:0044242 52 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
protein localization to membrane GO:0072657 108 0.014
developmental maturation GO:0021700 193 0.014
axonogenesis GO:0007409 274 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of cell cycle GO:0051726 281 0.014
response to acid chemical GO:0001101 111 0.014
protein localization to plasma membrane GO:0072659 57 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
respiratory system development GO:0060541 190 0.014
macromolecule glycosylation GO:0043413 55 0.014
protein modification by small protein conjugation GO:0032446 187 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
response to organonitrogen compound GO:0010243 246 0.013
carbohydrate catabolic process GO:0016052 32 0.013
aminoglycan metabolic process GO:0006022 34 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
neuromuscular process controlling balance GO:0050885 59 0.013
oligosaccharide catabolic process GO:0009313 2 0.013
response to oxidative stress GO:0006979 123 0.013
action potential GO:0001508 78 0.013
regulation of cell shape GO:0008360 39 0.013
epithelial cell proliferation GO:0050673 174 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
fatty acid metabolic process GO:0006631 121 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of protein localization GO:0032880 231 0.013
wound healing GO:0042060 157 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.013
adaptive immune response GO:0002250 155 0.013
positive regulation of cell development GO:0010720 237 0.013
muscle contraction GO:0006936 101 0.013
calcium ion transport GO:0006816 159 0.013
blood vessel morphogenesis GO:0048514 285 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of actin filament based process GO:0032970 99 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.013
small molecule biosynthetic process GO:0044283 132 0.013
spermatogenesis GO:0007283 284 0.013
glycolipid metabolic process GO:0006664 25 0.013
cell recognition GO:0008037 83 0.013
activation of immune response GO:0002253 138 0.013
gland development GO:0048732 330 0.013
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.013
astrocyte cell migration GO:0043615 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
alcohol metabolic process GO:0006066 116 0.012
sequestering of calcium ion GO:0051208 18 0.012
organelle localization GO:0051640 179 0.012
immune effector process GO:0002252 321 0.012
regulation of interleukin 8 secretion GO:2000482 2 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
renal system development GO:0072001 225 0.012
mitotic cell cycle GO:0000278 195 0.012
gliogenesis GO:0042063 141 0.012
myotube differentiation GO:0014902 105 0.012
glycosylation GO:0070085 62 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
glycerophospholipid metabolic process GO:0006650 71 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
dna metabolic process GO:0006259 303 0.012
lateral inhibition GO:0046331 1 0.012
smad protein signal transduction GO:0060395 21 0.012
membrane tubulation GO:0097320 4 0.012
protein glycosylation GO:0006486 55 0.012
hexose metabolic process GO:0019318 98 0.012
regulation of defense response GO:0031347 233 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
mitochondrion organization GO:0007005 134 0.012
glycerolipid metabolic process GO:0046486 122 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
kidney development GO:0001822 213 0.012
regulation of intracellular transport GO:0032386 159 0.012
rho protein signal transduction GO:0007266 32 0.012
regulation of secretion by cell GO:1903530 249 0.012
negative regulation of protein modification process GO:0031400 163 0.012
oligosaccharide metabolic process GO:0009311 11 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
transition metal ion homeostasis GO:0055076 54 0.012
membrane depolarization GO:0051899 64 0.012
lipid catabolic process GO:0016042 69 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
positive regulation of protein transport GO:0051222 93 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
positive regulation of kinase activity GO:0033674 155 0.011
t cell activation GO:0042110 289 0.011
regulation of cellular response to stress GO:0080135 159 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
protein oligomerization GO:0051259 67 0.011
actin filament organization GO:0007015 113 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
transmission of nerve impulse GO:0019226 76 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
muscle system process GO:0003012 141 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
multi multicellular organism process GO:0044706 109 0.011
regulation of homeostatic process GO:0032844 182 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
regulation of neuron projection development GO:0010975 169 0.011
regulation of cell projection organization GO:0031344 206 0.011
innate immune response GO:0045087 157 0.011
positive regulation of cytokine production GO:0001819 174 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
liposaccharide metabolic process GO:1903509 27 0.011
ear development GO:0043583 200 0.011
mitotic cytokinesis GO:0000281 4 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
monosaccharide metabolic process GO:0005996 106 0.011
synaptic transmission GO:0007268 329 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
regulation of cell migration GO:0030334 219 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
rhythmic process GO:0048511 174 0.011
glutamate metabolic process GO:0006536 9 0.011
negative regulation of organelle organization GO:0010639 90 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
positive regulation of transferase activity GO:0051347 167 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
sulfur compound metabolic process GO:0006790 100 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
positive regulation of proteolysis GO:0045862 85 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
regulation of protein transport GO:0051223 163 0.011
compound eye development GO:0048749 1 0.010
cell substrate adhesion GO:0031589 130 0.010
sensory organ morphogenesis GO:0090596 242 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
response to inorganic substance GO:0010035 96 0.010
extracellular matrix organization GO:0030198 147 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
cellular modified amino acid metabolic process GO:0006575 63 0.010
cellular protein catabolic process GO:0044257 155 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
positive regulation of interleukin 8 production GO:0032757 2 0.010
ensheathment of neurons GO:0007272 76 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
bone resorption GO:0045453 38 0.010
inorganic anion transport GO:0015698 43 0.010
atp catabolic process GO:0006200 55 0.010
establishment of protein localization to membrane GO:0090150 54 0.010
regulation of transmembrane transport GO:0034762 128 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
angiogenesis GO:0001525 201 0.010
axon ensheathment GO:0008366 76 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
cell growth GO:0016049 130 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
positive regulation of intracellular transport GO:0032388 70 0.010
lymphocyte differentiation GO:0030098 242 0.010
positive regulation of b cell receptor signaling pathway GO:0050861 4 0.010

Manba disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.402
inherited metabolic disorder DOID:655 0 0.402
lysosomal storage disease DOID:3211 0 0.144
lipid storage disease DOID:9455 0 0.108
central nervous system disease DOID:331 0 0.046
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.046
sphingolipidosis DOID:1927 0 0.036
brain disease DOID:936 0 0.030
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017
cerebral degeneration DOID:1443 0 0.017
sensory system disease DOID:0050155 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
bone disease DOID:0080001 0 0.015
immune system disease DOID:2914 0 0.014
organ system cancer DOID:0050686 0 0.012