Mus musculus

0 known processes

Mdh1

malate dehydrogenase 1, NAD (soluble)

(Aliases: MDHA,Mor2,D17921,Mor-2,MDH-s,B230377B03Rik)

Mdh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutamate biosynthetic process GO:0006537 2 0.551
ion transmembrane transport GO:0034220 361 0.395
aspartate family amino acid metabolic process GO:0009066 10 0.379
glutamine family amino acid biosynthetic process GO:0009084 2 0.299
oxidation reduction process GO:0055114 342 0.250
transmembrane transport GO:0055085 412 0.218
carboxylic acid catabolic process GO:0046395 51 0.201
purine containing compound metabolic process GO:0072521 311 0.183
alpha amino acid catabolic process GO:1901606 18 0.149
cellular amino acid metabolic process GO:0006520 103 0.135
nucleotide metabolic process GO:0009117 332 0.133
nadh metabolic process GO:0006734 1 0.131
cellular ketone metabolic process GO:0042180 84 0.128
organic hydroxy compound metabolic process GO:1901615 203 0.118
organonitrogen compound catabolic process GO:1901565 264 0.116
carboxylic acid biosynthetic process GO:0046394 86 0.111
coenzyme metabolic process GO:0006732 52 0.108
cellular nitrogen compound catabolic process GO:0044270 280 0.104
glycosyl compound metabolic process GO:1901657 246 0.103
purine nucleotide metabolic process GO:0006163 302 0.103
small molecule catabolic process GO:0044282 71 0.096
dicarboxylic acid catabolic process GO:0043649 2 0.095
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.094
glutamate metabolic process GO:0006536 9 0.084
nucleobase containing small molecule metabolic process GO:0055086 352 0.082
atp metabolic process GO:0046034 75 0.081
cellular chemical homeostasis GO:0055082 215 0.080
aspartate family amino acid biosynthetic process GO:0009067 5 0.079
cation homeostasis GO:0055080 212 0.077
alpha amino acid biosynthetic process GO:1901607 15 0.075
dicarboxylic acid metabolic process GO:0043648 18 0.075
organic acid biosynthetic process GO:0016053 86 0.075
organic acid catabolic process GO:0016054 51 0.074
cellular amino acid catabolic process GO:0009063 25 0.074
dna metabolic process GO:0006259 303 0.073
small molecule biosynthetic process GO:0044283 132 0.073
nucleoside phosphate metabolic process GO:0006753 338 0.073
fatty acid metabolic process GO:0006631 121 0.072
purine nucleoside metabolic process GO:0042278 241 0.071
purine ribonucleotide metabolic process GO:0009150 290 0.070
regulation of cellular ketone metabolic process GO:0010565 66 0.066
2 oxoglutarate metabolic process GO:0006103 7 0.064
cofactor metabolic process GO:0051186 80 0.064
nucleoside metabolic process GO:0009116 246 0.063
energy derivation by oxidation of organic compounds GO:0015980 77 0.062
steroid metabolic process GO:0008202 119 0.061
nucleoside triphosphate catabolic process GO:0009143 205 0.059
cellular ion homeostasis GO:0006873 165 0.059
ribonucleotide catabolic process GO:0009261 208 0.058
sterol metabolic process GO:0016125 58 0.055
cation transport GO:0006812 399 0.054
organonitrogen compound biosynthetic process GO:1901566 192 0.053
purine ribonucleoside metabolic process GO:0046128 241 0.051
amine metabolic process GO:0009308 45 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
anion transport GO:0006820 177 0.049
cellular amino acid biosynthetic process GO:0008652 22 0.049
regulation of ion transport GO:0043269 215 0.048
organic cyclic compound catabolic process GO:1901361 295 0.047
nucleoside monophosphate metabolic process GO:0009123 85 0.046
ribonucleoside metabolic process GO:0009119 245 0.046
carbohydrate derivative catabolic process GO:1901136 231 0.044
purine nucleoside monophosphate metabolic process GO:0009126 81 0.044
lateral inhibition GO:0046331 1 0.044
aromatic compound catabolic process GO:0019439 286 0.043
heterocycle catabolic process GO:0046700 280 0.041
mitochondrial calcium ion homeostasis GO:0051560 7 0.040
cellular metal ion homeostasis GO:0006875 151 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
alpha amino acid metabolic process GO:1901605 59 0.037
cellular carbohydrate metabolic process GO:0044262 119 0.037
citrate metabolic process GO:0006101 3 0.036
cellular alcohol biosynthetic process GO:0044108 3 0.036
organic hydroxy compound biosynthetic process GO:1901617 77 0.035
alcohol metabolic process GO:0006066 116 0.035
regulation of mitochondrial fission GO:0090140 3 0.035
monocarboxylic acid metabolic process GO:0032787 191 0.034
nucleotide catabolic process GO:0009166 217 0.034
cellular respiration GO:0045333 38 0.034
lipid homeostasis GO:0055088 63 0.033
metal ion homeostasis GO:0055065 189 0.033
ribonucleotide metabolic process GO:0009259 291 0.032
spermatid differentiation GO:0048515 115 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.031
nicotinamide nucleotide metabolic process GO:0046496 12 0.031
cellular response to peptide hormone stimulus GO:0071375 92 0.031
purine containing compound biosynthetic process GO:0072522 70 0.030
regulation of ion transmembrane transport GO:0034765 119 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
carbohydrate metabolic process GO:0005975 230 0.030
generation of precursor metabolites and energy GO:0006091 103 0.030
synaptic transmission GO:0007268 329 0.030
inorganic anion transport GO:0015698 43 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
cation transmembrane transport GO:0098655 266 0.029
homeostasis of number of cells GO:0048872 210 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
tricarboxylic acid metabolic process GO:0072350 5 0.029
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.028
alcohol biosynthetic process GO:0046165 43 0.027
ribonucleoside monophosphate metabolic process GO:0009161 80 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.027
neuron neuron synaptic transmission GO:0007270 69 0.027
cellular lipid metabolic process GO:0044255 323 0.026
cellular homeostasis GO:0019725 240 0.026
membrane organization GO:0061024 245 0.025
ribonucleoside monophosphate catabolic process GO:0009158 57 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
response to organic cyclic compound GO:0014070 198 0.024
response to radiation GO:0009314 165 0.024
cellular amine metabolic process GO:0044106 44 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
glutamine family amino acid metabolic process GO:0009064 15 0.023
nucleoside catabolic process GO:0009164 206 0.023
response to organonitrogen compound GO:0010243 246 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
organophosphate catabolic process GO:0046434 232 0.022
myeloid cell differentiation GO:0030099 233 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
carbohydrate biosynthetic process GO:0016051 74 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
atp catabolic process GO:0006200 55 0.021
calcium ion transmembrane transport GO:0070588 85 0.021
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
anion transmembrane transport GO:0098656 71 0.020
purine nucleoside monophosphate catabolic process GO:0009128 58 0.020
alditol metabolic process GO:0019400 5 0.020
sensory perception GO:0007600 245 0.020
t helper 17 cell chemotaxis GO:0035705 1 0.019
regulation of organelle organization GO:0033043 289 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
response to peptide GO:1901652 136 0.019
regulation of voltage gated calcium channel activity GO:1901385 4 0.019
glycerol metabolic process GO:0006071 3 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
glutamate catabolic process GO:0006538 2 0.018
positive regulation of catecholamine secretion GO:0033605 2 0.018
microtubule based process GO:0007017 236 0.018
cellular alcohol metabolic process GO:0044107 3 0.018
cellular response to insulin stimulus GO:0032869 78 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
blood vessel morphogenesis GO:0048514 285 0.018
spermatogenesis GO:0007283 284 0.018
monocarboxylic acid biosynthetic process GO:0072330 61 0.018
camera type eye development GO:0043010 266 0.017
cholesterol metabolic process GO:0008203 56 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
apoptotic nuclear changes GO:0030262 9 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
regulation of anion transport GO:0044070 27 0.017
sperm mitochondrion organization GO:0030382 2 0.017
response to light stimulus GO:0009416 135 0.017
positive regulation of cell death GO:0010942 224 0.016
regulation of dopamine secretion GO:0014059 9 0.016
cognition GO:0050890 149 0.016
fatty acid biosynthetic process GO:0006633 41 0.016
dna catabolic process endonucleolytic GO:0000737 15 0.016
nucleoside monophosphate catabolic process GO:0009125 59 0.016
divalent metal ion transport GO:0070838 172 0.016
cellularization GO:0007349 1 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
response to reactive oxygen species GO:0000302 56 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
spermatid development GO:0007286 108 0.015
calcium ion transport GO:0006816 159 0.015
response to peptide hormone GO:0043434 127 0.015
carboxylic acid transport GO:0046942 100 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
response to lipopolysaccharide GO:0032496 128 0.014
chromatin organization GO:0006325 206 0.014
calcium ion homeostasis GO:0055074 127 0.014
lipid biosynthetic process GO:0008610 179 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
angiogenesis GO:0001525 201 0.014
purine containing compound catabolic process GO:0072523 213 0.014
learning or memory GO:0007611 148 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
response to inorganic substance GO:0010035 96 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.014
positive regulation of atp biosynthetic process GO:2001171 2 0.014
germ cell development GO:0007281 185 0.014
regulation of ion transmembrane transporter activity GO:0032412 54 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.013
fat cell differentiation GO:0045444 160 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
forebrain development GO:0030900 302 0.013
maintenance of location GO:0051235 89 0.013
organelle fission GO:0048285 170 0.013
cytokine production GO:0001816 319 0.013
male gamete generation GO:0048232 285 0.013
positive regulation of protein modification process GO:0031401 299 0.013
detection of external stimulus GO:0009581 61 0.013
divalent inorganic cation transport GO:0072511 178 0.013
renal system development GO:0072001 225 0.013
regulation of intracellular transport GO:0032386 159 0.013
negative regulation of organelle organization GO:0010639 90 0.013
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
progesterone metabolic process GO:0042448 4 0.013
blood circulation GO:0008015 195 0.013
negative regulation of fatty acid metabolic process GO:0045922 10 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
sperm individualization GO:0007291 1 0.013
mitochondrion degradation GO:0000422 3 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
kidney development GO:0001822 213 0.012
peptidyl amino acid modification GO:0018193 336 0.012
purine ribonucleoside biosynthetic process GO:0046129 19 0.012
response to insulin GO:0032868 100 0.012
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.012
adult behavior GO:0030534 135 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
very long chain fatty acid catabolic process GO:0042760 2 0.012
nucleoside biosynthetic process GO:0009163 21 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
polyol metabolic process GO:0019751 26 0.012
circadian regulation of gene expression GO:0032922 48 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
retina development in camera type eye GO:0060041 119 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of transmembrane transport GO:0034762 128 0.012
compound eye development GO:0048749 1 0.012
ammonia assimilation cycle GO:0019676 2 0.012
hexose metabolic process GO:0019318 98 0.011
eosinophil degranulation GO:0043308 1 0.011
negative regulation of protein modification process GO:0031400 163 0.011
steroid biosynthetic process GO:0006694 47 0.011
organelle localization GO:0051640 179 0.011
cofactor transport GO:0051181 4 0.011
protein maturation GO:0051604 176 0.011
epithelial cell proliferation GO:0050673 174 0.011
inorganic anion transmembrane transport GO:0098661 29 0.011
regulation of ph GO:0006885 26 0.011
macromolecule catabolic process GO:0009057 281 0.011
purine nucleoside biosynthetic process GO:0042451 19 0.011
apoptotic signaling pathway GO:0097190 306 0.011
leukocyte differentiation GO:0002521 342 0.011
nitrogen compound transport GO:0071705 271 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
fertilization GO:0009566 127 0.011
urogenital system development GO:0001655 261 0.011
chemotaxis GO:0006935 247 0.011
monovalent inorganic cation homeostasis GO:0055067 33 0.011
positive regulation of dopamine secretion GO:0033603 2 0.011
response to oxidative stress GO:0006979 123 0.011
translation GO:0006412 93 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
striated muscle tissue development GO:0014706 293 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
regulation of transporter activity GO:0032409 57 0.010
mitotic cell cycle GO:0000278 195 0.010
regulation of translation GO:0006417 71 0.010
carbohydrate catabolic process GO:0016052 32 0.010
regulation of atp biosynthetic process GO:2001169 3 0.010
regulation of action potential GO:0098900 4 0.010
pyridine nucleotide metabolic process GO:0019362 12 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
intestinal epithelial structure maintenance GO:0060729 4 0.010
cellular modified amino acid metabolic process GO:0006575 63 0.010
intracellular protein transport GO:0006886 204 0.010
response to bile acid GO:1903412 1 0.010
leukocyte migration GO:0050900 124 0.010
pyridine containing compound metabolic process GO:0072524 14 0.010
regulation of myeloid leukocyte differentiation GO:0002761 58 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
positive regulation of t cell extravasation GO:2000409 2 0.010
negative regulation of response to oxidative stress GO:1902883 10 0.010
sequestering of calcium ion GO:0051208 18 0.010

Mdh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.061
sensory system disease DOID:0050155 0 0.061
disease of anatomical entity DOID:7 0 0.061
eye and adnexa disease DOID:1492 0 0.061
nervous system disease DOID:863 0 0.061
eye disease DOID:5614 0 0.061
disease of metabolism DOID:0014667 0 0.032
inherited metabolic disorder DOID:655 0 0.032
retinal degeneration DOID:8466 0 0.023
retinitis pigmentosa DOID:10584 0 0.023
immune system disease DOID:2914 0 0.017