Mus musculus

22 known processes

Tgm4

transglutaminase 4 (prostate)

(Aliases: 9530008N10Rik,TGP,Eapa1)

Tgm4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.123
cation transport GO:0006812 399 0.070
nitrogen compound transport GO:0071705 271 0.069
ion transmembrane transport GO:0034220 361 0.048
cation transmembrane transport GO:0098655 266 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
apoptotic signaling pathway GO:0097190 306 0.045
cellular ketone metabolic process GO:0042180 84 0.044
cellular amino acid metabolic process GO:0006520 103 0.043
membrane organization GO:0061024 245 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.042
regulation of organelle organization GO:0033043 289 0.041
g protein coupled receptor signaling pathway GO:0007186 243 0.040
oxidation reduction process GO:0055114 342 0.040
regulation of cell cycle GO:0051726 281 0.038
sulfur compound metabolic process GO:0006790 100 0.038
inorganic cation transmembrane transport GO:0098662 207 0.037
peptide transport GO:0015833 133 0.037
amine metabolic process GO:0009308 45 0.036
regulation of system process GO:0044057 200 0.036
nucleotide metabolic process GO:0009117 332 0.035
positive regulation of nervous system development GO:0051962 221 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
purine containing compound metabolic process GO:0072521 311 0.034
inorganic ion transmembrane transport GO:0098660 234 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.032
cation homeostasis GO:0055080 212 0.032
cellular amine metabolic process GO:0044106 44 0.032
endomembrane system organization GO:0010256 147 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.029
regulation of secretion by cell GO:1903530 249 0.029
cellular lipid metabolic process GO:0044255 323 0.029
negative regulation of cell proliferation GO:0008285 296 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
male gamete generation GO:0048232 285 0.028
camera type eye development GO:0043010 266 0.028
regulation of secretion GO:0051046 274 0.028
divalent metal ion transport GO:0070838 172 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.027
cytokine production GO:0001816 319 0.027
developmental maturation GO:0021700 193 0.027
cellular response to lipid GO:0071396 145 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
regulation of membrane potential GO:0042391 192 0.026
epidermis development GO:0008544 187 0.026
inflammatory response GO:0006954 244 0.026
sensory perception GO:0007600 245 0.026
cellular homeostasis GO:0019725 240 0.025
cellular chemical homeostasis GO:0055082 215 0.025
regulation of neuron differentiation GO:0045664 281 0.025
negative regulation of immune system process GO:0002683 209 0.025
epithelial tube morphogenesis GO:0060562 303 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
dna metabolic process GO:0006259 303 0.024
regulation of protein localization GO:0032880 231 0.024
nucleoside metabolic process GO:0009116 246 0.024
positive regulation of cell death GO:0010942 224 0.024
peptidyl amino acid modification GO:0018193 336 0.024
regulation of anatomical structure size GO:0090066 178 0.024
synaptic transmission GO:0007268 329 0.024
amide transport GO:0042886 138 0.023
positive regulation of cell development GO:0010720 237 0.023
regulation of ion transport GO:0043269 215 0.023
glucose homeostasis GO:0042593 128 0.023
regulation of transmembrane transport GO:0034762 128 0.023
regionalization GO:0003002 337 0.023
negative regulation of protein metabolic process GO:0051248 282 0.022
regulation of response to wounding GO:1903034 189 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
regulation of homeostatic process GO:0032844 182 0.022
cell type specific apoptotic process GO:0097285 268 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
negative regulation of molecular function GO:0044092 258 0.021
organic anion transport GO:0015711 137 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
response to organic cyclic compound GO:0014070 198 0.021
regulation of ion transmembrane transport GO:0034765 119 0.021
spermatogenesis GO:0007283 284 0.021
chromatin organization GO:0006325 206 0.021
lipid biosynthetic process GO:0008610 179 0.021
regulation of cell motility GO:2000145 236 0.021
anatomical structure homeostasis GO:0060249 145 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
mitotic cell cycle GO:0000278 195 0.021
skin development GO:0043588 220 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
divalent inorganic cation transport GO:0072511 178 0.020
regulation of hormone levels GO:0010817 211 0.020
cellular response to inorganic substance GO:0071241 37 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
metal ion homeostasis GO:0055065 189 0.020
regulation of protein kinase activity GO:0045859 232 0.020
stem cell development GO:0048864 219 0.020
chromatin modification GO:0016568 187 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
gland development GO:0048732 330 0.019
regulation of metal ion transport GO:0010959 106 0.019
myeloid cell differentiation GO:0030099 233 0.019
negative regulation of cellular amine metabolic process GO:0033239 1 0.019
cytoplasmic transport GO:0016482 234 0.019
skeletal system development GO:0001501 356 0.019
regulation of kinase activity GO:0043549 249 0.019
sequestering of metal ion GO:0051238 19 0.019
dephosphorylation GO:0016311 129 0.019
striated muscle tissue development GO:0014706 293 0.019
stem cell differentiation GO:0048863 268 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
regulation of proteolysis GO:0030162 164 0.018
response to organonitrogen compound GO:0010243 246 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
regulation of feeding behavior GO:0060259 3 0.018
cellular ion homeostasis GO:0006873 165 0.018
positive regulation of organelle organization GO:0010638 128 0.018
ossification GO:0001503 216 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
organic acid transport GO:0015849 101 0.018
regulation of binding GO:0051098 111 0.018
aromatic compound catabolic process GO:0019439 286 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
alcohol metabolic process GO:0006066 116 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
heterocycle catabolic process GO:0046700 280 0.018
small molecule biosynthetic process GO:0044283 132 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
homeostasis of number of cells GO:0048872 210 0.017
calcium ion transport GO:0006816 159 0.017
asymmetric stem cell division GO:0098722 3 0.017
germ cell development GO:0007281 185 0.017
leukocyte differentiation GO:0002521 342 0.017
organelle fission GO:0048285 170 0.017
carboxylic acid transport GO:0046942 100 0.017
cell adhesion GO:0007155 329 0.017
detection of stimulus GO:0051606 84 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
circulatory system process GO:0003013 197 0.017
regulation of lipid metabolic process GO:0019216 118 0.016
regulation of neuron projection development GO:0010975 169 0.016
forebrain development GO:0030900 302 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
sequestering of calcium ion GO:0051208 18 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
peptide secretion GO:0002790 114 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
calcium ion homeostasis GO:0055074 127 0.016
protein localization to membrane GO:0072657 108 0.016
epithelial cell development GO:0002064 159 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
amino acid transmembrane transport GO:0003333 37 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
cellular response to abiotic stimulus GO:0071214 56 0.016
carbohydrate metabolic process GO:0005975 230 0.016
mitochondrion organization GO:0007005 134 0.016
fatty acid metabolic process GO:0006631 121 0.015
response to inorganic substance GO:0010035 96 0.015
cell fate commitment GO:0045165 210 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
maintenance of location GO:0051235 89 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
spermatid development GO:0007286 108 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
response to radiation GO:0009314 165 0.015
sensory organ morphogenesis GO:0090596 242 0.015
regulation of cellular response to stress GO:0080135 159 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
regulation of transferase activity GO:0051338 263 0.015
neural precursor cell proliferation GO:0061351 121 0.015
cell recognition GO:0008037 83 0.015
regulation of cytokine production GO:0001817 266 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
neuron death GO:0070997 154 0.015
adult behavior GO:0030534 135 0.015
tissue homeostasis GO:0001894 115 0.015
male genitalia morphogenesis GO:0048808 4 0.015
muscle tissue development GO:0060537 308 0.015
epithelial cell proliferation GO:0050673 174 0.015
nuclear division GO:0000280 158 0.015
anion transport GO:0006820 177 0.014
organelle localization GO:0051640 179 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
skeletal muscle organ development GO:0060538 163 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
fat cell differentiation GO:0045444 160 0.014
mapk cascade GO:0000165 281 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
positive regulation of protein modification process GO:0031401 299 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of mapk cascade GO:0043408 248 0.014
rho protein signal transduction GO:0007266 32 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
muscle cell differentiation GO:0042692 261 0.014
macromolecule catabolic process GO:0009057 281 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
response to light stimulus GO:0009416 135 0.014
locomotory behavior GO:0007626 195 0.014
learning or memory GO:0007611 148 0.014
plasma membrane organization GO:0007009 90 0.014
regulation of cell cycle process GO:0010564 160 0.014
negative regulation of protein modification process GO:0031400 163 0.014
membrane depolarization GO:0051899 64 0.014
carbohydrate homeostasis GO:0033500 128 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
adult locomotory behavior GO:0008344 91 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
regulation of cell adhesion GO:0030155 154 0.013
regulation of hydrolase activity GO:0051336 246 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
urogenital system development GO:0001655 261 0.013
cartilage development GO:0051216 140 0.013
molting cycle GO:0042303 90 0.013
hormone secretion GO:0046879 128 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of cell migration GO:0030334 219 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
protein ubiquitination GO:0016567 171 0.013
development of primary sexual characteristics GO:0045137 143 0.013
hindbrain development GO:0030902 128 0.013
cell maturation GO:0048469 127 0.013
blood circulation GO:0008015 195 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
neuromuscular process GO:0050905 99 0.013
regulation of defense response GO:0031347 233 0.013
steroid metabolic process GO:0008202 119 0.013
intracellular protein transport GO:0006886 204 0.013
organophosphate catabolic process GO:0046434 232 0.013
amino acid transport GO:0006865 61 0.013
peptide hormone secretion GO:0030072 109 0.013
response to acid chemical GO:0001101 111 0.013
glycoprotein metabolic process GO:0009100 116 0.013
mitotic cell cycle process GO:1903047 159 0.013
telencephalon development GO:0021537 186 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
renal system development GO:0072001 225 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of cell growth GO:0001558 91 0.013
blood vessel morphogenesis GO:0048514 285 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
stem cell maintenance GO:0019827 130 0.013
multi multicellular organism process GO:0044706 109 0.013
macromolecule methylation GO:0043414 120 0.013
peptidyl serine modification GO:0018209 83 0.013
translation GO:0006412 93 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
nucleoside phosphate catabolic process GO:1901292 222 0.012
positive regulation of secretion GO:0051047 130 0.012
retina development in camera type eye GO:0060041 119 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
rhythmic process GO:0048511 174 0.012
tube formation GO:0035148 140 0.012
microtubule based process GO:0007017 236 0.012
regulation of organ morphogenesis GO:2000027 144 0.012
axonogenesis GO:0007409 274 0.012
cellular protein catabolic process GO:0044257 155 0.012
protein maturation GO:0051604 176 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of peptidase activity GO:0052547 96 0.012
methylation GO:0032259 134 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
transmission of nerve impulse GO:0019226 76 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
cellular response to external stimulus GO:0071496 88 0.012
lipid transport GO:0006869 98 0.012
muscle system process GO:0003012 141 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
regulation of inflammatory response GO:0050727 147 0.012
response to nutrient levels GO:0031667 109 0.012
connective tissue development GO:0061448 179 0.012
immune effector process GO:0002252 321 0.012
purine containing compound biosynthetic process GO:0072522 70 0.012
covalent chromatin modification GO:0016569 163 0.012
nuclear transport GO:0051169 139 0.012
limb development GO:0060173 166 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
response to lipopolysaccharide GO:0032496 128 0.011
regulation of intracellular transport GO:0032386 159 0.011
response to oxygen levels GO:0070482 62 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
regulation of map kinase activity GO:0043405 120 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
regulation of peptide secretion GO:0002791 77 0.011
regulation of calcium ion transport GO:0051924 69 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
compound eye development GO:0048749 1 0.011
neuron apoptotic process GO:0051402 142 0.011
negative regulation of cell cycle GO:0045786 123 0.011
ear development GO:0043583 200 0.011
cognition GO:0050890 149 0.011
intracellular receptor signaling pathway GO:0030522 74 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
detection of molecule of bacterial origin GO:0032490 2 0.011
skeletal system morphogenesis GO:0048705 203 0.011
histone modification GO:0016570 159 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of ossification GO:0030278 112 0.011
negative regulation of cell development GO:0010721 169 0.011
regulation of transporter activity GO:0032409 57 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
placenta development GO:0001890 140 0.011
nucleoside triphosphate metabolic process GO:0009141 230 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
detection of bacterial lipoprotein GO:0042494 1 0.011
regulation of body fluid levels GO:0050878 162 0.011
negative regulation of organelle organization GO:0010639 90 0.011
rna processing GO:0006396 105 0.011
respiratory tube development GO:0030323 167 0.011
organelle assembly GO:0070925 177 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
negative regulation of nervous system development GO:0051961 156 0.011
regulation of ion transmembrane transporter activity GO:0032412 54 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
hair follicle development GO:0001942 85 0.011
multicellular organismal signaling GO:0035637 91 0.011
regulation of chromosome organization GO:0033044 83 0.011
insulin secretion GO:0030073 89 0.010
regulation of protein transport GO:0051223 163 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
exocytosis GO:0006887 121 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
neural tube development GO:0021915 160 0.010
cell division GO:0051301 120 0.010
nucleoside catabolic process GO:0009164 206 0.010
protein catabolic process GO:0030163 221 0.010
nucleotide catabolic process GO:0009166 217 0.010
negative regulation of defense response GO:0031348 77 0.010
digestive system development GO:0055123 200 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
synapse organization GO:0050808 125 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
cofactor metabolic process GO:0051186 80 0.010
male gonad development GO:0008584 88 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
protein processing GO:0016485 163 0.010
peptidyl serine phosphorylation GO:0018105 74 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
oocyte construction GO:0007308 2 0.010
regulation of peptide transport GO:0090087 91 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
interleukin 8 production GO:0032637 4 0.010
modification dependent macromolecule catabolic process GO:0043632 133 0.010
response to extracellular stimulus GO:0009991 127 0.010
male anatomical structure morphogenesis GO:0090598 4 0.010
protein oligomerization GO:0051259 67 0.010
tissue remodeling GO:0048771 102 0.010
cell growth GO:0016049 130 0.010
respiratory system development GO:0060541 190 0.010
regulation of cellular protein catabolic process GO:1903362 61 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
hydrogen transport GO:0006818 35 0.010
t cell activation GO:0042110 289 0.010

Tgm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of metabolism DOID:0014667 0 0.023
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.017
retinal disease DOID:5679 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
acquired metabolic disease DOID:0060158 0 0.012
immune system disease DOID:2914 0 0.010