Mus musculus

49 known processes

Ambra1

autophagy/beclin 1 regulator 1

(Aliases: A130023A14,mKIAA1736,2310079H06Rik,AV021921,D030051N19Rik,AA474864)

Ambra1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound catabolic process GO:0044270 280 0.082
macromolecule catabolic process GO:0009057 281 0.078
dna metabolic process GO:0006259 303 0.076
organelle fission GO:0048285 170 0.067
chromatin organization GO:0006325 206 0.066
aromatic compound catabolic process GO:0019439 286 0.065
histone methylation GO:0016571 71 0.058
heterocycle catabolic process GO:0046700 280 0.054
cellular macromolecule catabolic process GO:0044265 206 0.052
rna processing GO:0006396 105 0.051
regulation of organelle organization GO:0033043 289 0.051
ribonucleotide metabolic process GO:0009259 291 0.050
methylation GO:0032259 134 0.048
protein modification by small protein conjugation GO:0032446 187 0.045
covalent chromatin modification GO:0016569 163 0.045
purine nucleotide metabolic process GO:0006163 302 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.041
mrna metabolic process GO:0016071 84 0.038
nucleotide metabolic process GO:0009117 332 0.036
organic cyclic compound catabolic process GO:1901361 295 0.036
regulation of cellular ketone metabolic process GO:0010565 66 0.036
blastocyst growth GO:0001832 23 0.035
organophosphate catabolic process GO:0046434 232 0.035
histone modification GO:0016570 159 0.035
chromatin modification GO:0016568 187 0.034
positive regulation of dna templated transcription elongation GO:0032786 2 0.033
mrna processing GO:0006397 63 0.032
negative regulation of molecular function GO:0044092 258 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
amine metabolic process GO:0009308 45 0.031
rna splicing GO:0008380 54 0.031
germ cell development GO:0007281 185 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
cellular ketone metabolic process GO:0042180 84 0.030
peptidyl amino acid modification GO:0018193 336 0.030
purine containing compound catabolic process GO:0072523 213 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
immune effector process GO:0002252 321 0.028
meiotic cell cycle GO:0051321 122 0.028
regulation of neuron differentiation GO:0045664 281 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
synaptic transmission GO:0007268 329 0.028
negative regulation of protein metabolic process GO:0051248 282 0.027
blastocyst development GO:0001824 80 0.027
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.027
cytoplasmic transport GO:0016482 234 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
organonitrogen compound catabolic process GO:1901565 264 0.026
nitrogen compound transport GO:0071705 271 0.026
intracellular protein transport GO:0006886 204 0.026
nuclear division GO:0000280 158 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
ossification GO:0001503 216 0.026
regulation of transcription during meiosis GO:0051037 1 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
purine nucleoside catabolic process GO:0006152 205 0.025
purine containing compound metabolic process GO:0072521 311 0.024
cellular amine metabolic process GO:0044106 44 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
purine nucleoside metabolic process GO:0042278 241 0.023
nucleoside metabolic process GO:0009116 246 0.023
transcription from rna polymerase iii promoter GO:0006383 3 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
protein ubiquitination GO:0016567 171 0.023
compound eye development GO:0048749 1 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
negative regulation of protein modification process GO:0031400 163 0.022
cognition GO:0050890 149 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
oxidation reduction process GO:0055114 342 0.021
spermatogenesis GO:0007283 284 0.021
regulation of nucleotide metabolic process GO:0006140 169 0.021
negative regulation of organelle organization GO:0010639 90 0.021
cellular homeostasis GO:0019725 240 0.021
regionalization GO:0003002 337 0.021
protein localization to organelle GO:0033365 185 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
nucleoside catabolic process GO:0009164 206 0.021
locomotory behavior GO:0007626 195 0.021
maintenance of location GO:0051235 89 0.020
cell division GO:0051301 120 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
skeletal system development GO:0001501 356 0.020
meiosis i GO:0007127 60 0.020
meiotic nuclear division GO:0007126 115 0.020
dna repair GO:0006281 107 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
nucleotide catabolic process GO:0009166 217 0.020
learning or memory GO:0007611 148 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
purine nucleotide catabolic process GO:0006195 211 0.019
male gamete generation GO:0048232 285 0.019
protein targeting GO:0006605 143 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.019
regulation of protein localization GO:0032880 231 0.019
cellular protein catabolic process GO:0044257 155 0.019
cell type specific apoptotic process GO:0097285 268 0.019
protein maturation GO:0051604 176 0.018
response to extracellular stimulus GO:0009991 127 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
apoptotic signaling pathway GO:0097190 306 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
organelle localization GO:0051640 179 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
cellular chemical homeostasis GO:0055082 215 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
regulation of membrane potential GO:0042391 192 0.017
anatomical structure homeostasis GO:0060249 145 0.017
adult behavior GO:0030534 135 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
cation transport GO:0006812 399 0.017
camera type eye development GO:0043010 266 0.017
regulation of defense response GO:0031347 233 0.017
histone lysine methylation GO:0034968 50 0.017
leukocyte differentiation GO:0002521 342 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
urogenital system development GO:0001655 261 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
lipid biosynthetic process GO:0008610 179 0.016
neuronal action potential GO:0019228 54 0.016
nuclear transport GO:0051169 139 0.016
glucose homeostasis GO:0042593 128 0.016
regulation of homeostatic process GO:0032844 182 0.016
protein catabolic process GO:0030163 221 0.016
positive regulation of nervous system development GO:0051962 221 0.016
mitotic cell cycle GO:0000278 195 0.016
regulation of chromosome organization GO:0033044 83 0.016
development of primary sexual characteristics GO:0045137 143 0.016
regulation of cell cycle process GO:0010564 160 0.016
regulation of mrna processing GO:0050684 41 0.016
sensory perception of mechanical stimulus GO:0050954 107 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
membrane organization GO:0061024 245 0.016
digestive system development GO:0055123 200 0.016
positive regulation of cell death GO:0010942 224 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
leukocyte activation involved in immune response GO:0002366 126 0.015
gtp catabolic process GO:0006184 143 0.015
inner cell mass cell proliferation GO:0001833 15 0.015
renal system development GO:0072001 225 0.015
lipid localization GO:0010876 126 0.015
wnt signaling pathway GO:0016055 188 0.015
multi multicellular organism process GO:0044706 109 0.015
carbohydrate homeostasis GO:0033500 128 0.015
nuclear import GO:0051170 95 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
regulation of cell cycle GO:0051726 281 0.015
regulation of hormone levels GO:0010817 211 0.015
regulation of reactive oxygen species metabolic process GO:2000377 40 0.015
anion transport GO:0006820 177 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
respiratory system development GO:0060541 190 0.014
mitotic cell cycle process GO:1903047 159 0.014
mrna splicing via spliceosome GO:0000398 43 0.014
cellular lipid metabolic process GO:0044255 323 0.014
regulation of mrna metabolic process GO:1903311 43 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
response to organonitrogen compound GO:0010243 246 0.014
regulation of cellular response to stress GO:0080135 159 0.014
rna splicing via transesterification reactions GO:0000375 43 0.014
gonad development GO:0008406 141 0.014
regulation of hydrolase activity GO:0051336 246 0.014
cation transmembrane transport GO:0098655 266 0.014
sensory organ morphogenesis GO:0090596 242 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
gene silencing by mirna GO:0035195 10 0.014
multicellular organismal signaling GO:0035637 91 0.014
positive regulation of kinase activity GO:0033674 155 0.014
stem cell differentiation GO:0048863 268 0.014
organelle assembly GO:0070925 177 0.014
regulation of proteolysis GO:0030162 164 0.013
transmembrane transport GO:0055085 412 0.013
sensory perception GO:0007600 245 0.013
regulation of rna splicing GO:0043484 37 0.013
protein processing GO:0016485 163 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
negative regulation of wnt signaling pathway GO:0030178 73 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
heart morphogenesis GO:0003007 178 0.013
cytokine production GO:0001816 319 0.013
posttranscriptional gene silencing GO:0016441 10 0.013
axonogenesis GO:0007409 274 0.013
blood circulation GO:0008015 195 0.013
regulation of protein kinase activity GO:0045859 232 0.013
small molecule biosynthetic process GO:0044283 132 0.013
muscle tissue development GO:0060537 308 0.013
gtp metabolic process GO:0046039 144 0.013
internal peptidyl lysine acetylation GO:0018393 42 0.013
protein methylation GO:0006479 81 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of cell projection organization GO:0031344 206 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.012
regulation of mapk cascade GO:0043408 248 0.012
response to oxidative stress GO:0006979 123 0.012
synapsis GO:0007129 34 0.012
ras protein signal transduction GO:0007265 77 0.012
limb development GO:0060173 166 0.012
regulation of cell migration GO:0030334 219 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
stem cell development GO:0048864 219 0.012
rna interference GO:0016246 2 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
respiratory tube development GO:0030323 167 0.012
hexose metabolic process GO:0019318 98 0.012
circulatory system process GO:0003013 197 0.012
vesicle localization GO:0051648 86 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
peptidyl lysine methylation GO:0018022 29 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of cell activation GO:0050865 289 0.012
homeostasis of number of cells GO:0048872 210 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
organic acid biosynthetic process GO:0016053 86 0.012
multicellular organism growth GO:0035264 161 0.012
response to nutrient levels GO:0031667 109 0.012
defense response to other organism GO:0098542 197 0.012
lung development GO:0030324 164 0.012
internal protein amino acid acetylation GO:0006475 42 0.012
protein localization to nucleus GO:0034504 121 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
neuron projection guidance GO:0097485 141 0.011
dna conformation change GO:0071103 37 0.011
negative regulation of chromosome organization GO:2001251 30 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
positive regulation of protein modification process GO:0031401 299 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
sensory system development GO:0048880 3 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
action potential GO:0001508 78 0.011
mapk cascade GO:0000165 281 0.011
gland development GO:0048732 330 0.011
atp metabolic process GO:0046034 75 0.011
response to organic cyclic compound GO:0014070 198 0.011
female gamete generation GO:0007292 74 0.011
endocytosis GO:0006897 168 0.011
forebrain development GO:0030900 302 0.011
intracellular mrna localization GO:0008298 4 0.011
regulation of cell division GO:0051302 76 0.011
epithelial cell proliferation GO:0050673 174 0.011
response to acid chemical GO:0001101 111 0.011
b cell activation involved in immune response GO:0002312 50 0.011
cellular response to starvation GO:0009267 57 0.011
chemotaxis GO:0006935 247 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
single organism nuclear import GO:1902593 95 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of intracellular transport GO:0032386 159 0.011
male meiosis i GO:0007141 16 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
myeloid cell differentiation GO:0030099 233 0.011
kidney development GO:0001822 213 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
cellular response to nutrient levels GO:0031669 64 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
dephosphorylation GO:0016311 129 0.011
regulation of protein catabolic process GO:0042176 108 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of kinase activity GO:0043549 249 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
microtubule based process GO:0007017 236 0.011
innate immune response GO:0045087 157 0.011
sensory perception of sound GO:0007605 97 0.011
cellular response to lipid GO:0071396 145 0.011
regulation of secretion GO:0051046 274 0.010
regulation of system process GO:0044057 200 0.010
rhythmic process GO:0048511 174 0.010
organonitrogen compound biosynthetic process GO:1901566 192 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
carbohydrate metabolic process GO:0005975 230 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
response to starvation GO:0042594 65 0.010
vacuole organization GO:0007033 38 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
digestive tract morphogenesis GO:0048546 147 0.010
male meiosis GO:0007140 37 0.010
olfactory nerve development GO:0021553 3 0.010
epithalamus development GO:0021538 2 0.010
double strand break repair GO:0006302 48 0.010
cell activation involved in immune response GO:0002263 126 0.010
small gtpase mediated signal transduction GO:0007264 97 0.010

Ambra1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
immune system disease DOID:2914 0 0.014
hematopoietic system disease DOID:74 0 0.012
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.010