Mus musculus

0 known processes

Dram1

DNA-damage regulated autophagy modulator 1

(Aliases: Dram,1200002N14Rik)

Dram1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.121
regulation of cytokine production GO:0001817 266 0.098
defense response to bacterium GO:0042742 119 0.091
cellular amine metabolic process GO:0044106 44 0.083
immune effector process GO:0002252 321 0.082
regulation of cellular amino acid metabolic process GO:0006521 5 0.076
regulation of secretion GO:0051046 274 0.074
positive regulation of cellular amine metabolic process GO:0033240 5 0.071
regulation of cellular amine metabolic process GO:0033238 20 0.067
cellular amino acid metabolic process GO:0006520 103 0.062
apoptotic signaling pathway GO:0097190 306 0.060
amine metabolic process GO:0009308 45 0.059
innate immune response GO:0045087 157 0.057
response to molecule of bacterial origin GO:0002237 143 0.057
cation transport GO:0006812 399 0.056
cellular ketone metabolic process GO:0042180 84 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.055
response to lipopolysaccharide GO:0032496 128 0.050
leukocyte differentiation GO:0002521 342 0.049
negative regulation of immune system process GO:0002683 209 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
regulation of innate immune response GO:0045088 91 0.046
regulation of secretion by cell GO:1903530 249 0.045
negative regulation of cytokine production GO:0001818 84 0.044
anion transport GO:0006820 177 0.044
positive regulation of defense response GO:0031349 124 0.043
t cell activation GO:0042110 289 0.043
mapk cascade GO:0000165 281 0.042
response to organonitrogen compound GO:0010243 246 0.042
regulation of protein localization GO:0032880 231 0.040
cell adhesion GO:0007155 329 0.040
g protein coupled receptor signaling pathway GO:0007186 243 0.039
leukocyte migration GO:0050900 124 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
cellular response to lipid GO:0071396 145 0.034
inflammatory response GO:0006954 244 0.034
regulation of cell motility GO:2000145 236 0.033
leukocyte mediated immunity GO:0002443 174 0.033
organic anion transport GO:0015711 137 0.033
macromolecule catabolic process GO:0009057 281 0.032
myeloid leukocyte activation GO:0002274 83 0.032
peptidyl amino acid modification GO:0018193 336 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.031
transmembrane transport GO:0055085 412 0.030
regulation of t cell activation GO:0050863 170 0.030
regulation of cell activation GO:0050865 289 0.030
oxidation reduction process GO:0055114 342 0.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.030
nucleotide metabolic process GO:0009117 332 0.029
regulation of mapk cascade GO:0043408 248 0.028
lymphocyte mediated immunity GO:0002449 139 0.028
protein catabolic process GO:0030163 221 0.028
negative regulation of cell activation GO:0050866 111 0.028
positive regulation of cytokine production GO:0001819 174 0.027
cell activation involved in immune response GO:0002263 126 0.027
calcium ion transport GO:0006816 159 0.027
spermatogenesis GO:0007283 284 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
endocytosis GO:0006897 168 0.027
immune response activating signal transduction GO:0002757 116 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
negative regulation of lymphocyte activation GO:0051250 91 0.026
extracellular structure organization GO:0043062 148 0.026
regulation of intracellular transport GO:0032386 159 0.026
response to nutrient levels GO:0031667 109 0.026
cellular response to acid chemical GO:0071229 68 0.026
regulation of lymphocyte activation GO:0051249 240 0.025
regulation of system process GO:0044057 200 0.025
immune response regulating signaling pathway GO:0002764 125 0.025
regulation of protein transport GO:0051223 163 0.025
regulation of organelle organization GO:0033043 289 0.025
male gamete generation GO:0048232 285 0.025
t cell differentiation GO:0030217 174 0.025
regulation of defense response GO:0031347 233 0.024
chemotaxis GO:0006935 247 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
rho protein signal transduction GO:0007266 32 0.024
cellular response to lipopolysaccharide GO:0071222 77 0.024
regulation of cellular response to stress GO:0080135 159 0.024
exocytosis GO:0006887 121 0.024
regulation of leukocyte mediated immunity GO:0002703 104 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
glucose homeostasis GO:0042593 128 0.024
response to acid chemical GO:0001101 111 0.024
nitrogen compound transport GO:0071705 271 0.024
respiratory tube development GO:0030323 167 0.023
homeostasis of number of cells GO:0048872 210 0.023
cytokine secretion GO:0050663 72 0.023
synaptic transmission GO:0007268 329 0.023
interleukin 8 production GO:0032637 4 0.023
cellular response to biotic stimulus GO:0071216 92 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
interspecies interaction between organisms GO:0044419 83 0.023
positive regulation of cell death GO:0010942 224 0.023
regulation of body fluid levels GO:0050878 162 0.023
glycosyl compound metabolic process GO:1901657 246 0.022
regulation of production of molecular mediator of immune response GO:0002700 65 0.022
response to amino acid GO:0043200 37 0.022
aromatic compound catabolic process GO:0019439 286 0.022
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
regulation of lymphocyte proliferation GO:0050670 117 0.022
defense response to other organism GO:0098542 197 0.022
extracellular matrix organization GO:0030198 147 0.022
regulation of multi organism process GO:0043900 111 0.022
activation of immune response GO:0002253 138 0.022
activation of innate immune response GO:0002218 56 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
alpha beta t cell activation GO:0046631 91 0.021
divalent metal ion transport GO:0070838 172 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
ossification GO:0001503 216 0.021
cation homeostasis GO:0055080 212 0.021
ras protein signal transduction GO:0007265 77 0.021
lipid transport GO:0006869 98 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
regulation of membrane potential GO:0042391 192 0.021
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.021
protein maturation GO:0051604 176 0.021
cytoplasmic transport GO:0016482 234 0.021
positive regulation of programmed cell death GO:0043068 218 0.020
organic hydroxy compound transport GO:0015850 93 0.020
kidney development GO:0001822 213 0.020
cellular chemical homeostasis GO:0055082 215 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
membrane organization GO:0061024 245 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
heterocycle catabolic process GO:0046700 280 0.020
lymphocyte activation involved in immune response GO:0002285 93 0.020
lymphocyte differentiation GO:0030098 242 0.020
protein localization to nucleus GO:0034504 121 0.019
ion transmembrane transport GO:0034220 361 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
positive regulation of innate immune response GO:0045089 80 0.019
positive regulation of protein modification process GO:0031401 299 0.019
protein localization to organelle GO:0033365 185 0.019
negative regulation of protein maturation GO:1903318 79 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
response to inorganic substance GO:0010035 96 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
response to organic cyclic compound GO:0014070 198 0.019
regulation of proteolysis GO:0030162 164 0.019
lung development GO:0030324 164 0.018
regulation of inflammatory response GO:0050727 147 0.018
positive regulation of mapk cascade GO:0043410 170 0.018
b cell activation GO:0042113 161 0.018
regulation of protein catabolic process GO:0042176 108 0.018
cytokine mediated signaling pathway GO:0019221 115 0.018
regulation of neuron differentiation GO:0045664 281 0.018
response to radiation GO:0009314 165 0.018
purine containing compound metabolic process GO:0072521 311 0.018
carboxylic acid transport GO:0046942 100 0.018
chemokine production GO:0032602 34 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
regulation of hormone levels GO:0010817 211 0.017
positive regulation of secretion by cell GO:1903532 114 0.017
myeloid leukocyte mediated immunity GO:0002444 42 0.017
striated muscle tissue development GO:0014706 293 0.017
leukocyte proliferation GO:0070661 172 0.017
t cell mediated immunity GO:0002456 50 0.017
cellular homeostasis GO:0019725 240 0.017
divalent inorganic cation transport GO:0072511 178 0.017
dna metabolic process GO:0006259 303 0.017
blood vessel morphogenesis GO:0048514 285 0.017
carbohydrate homeostasis GO:0033500 128 0.017
action potential GO:0001508 78 0.017
organic acid transport GO:0015849 101 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
organelle localization GO:0051640 179 0.017
alpha beta t cell differentiation GO:0046632 69 0.016
lipid biosynthetic process GO:0008610 179 0.016
cellular ion homeostasis GO:0006873 165 0.016
nuclear transport GO:0051169 139 0.016
protein processing GO:0016485 163 0.016
development of primary male sexual characteristics GO:0046546 88 0.016
protein secretion GO:0009306 111 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.016
cell substrate adhesion GO:0031589 130 0.016
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of action potential GO:0098900 4 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of ion transport GO:0043269 215 0.016
response to extracellular stimulus GO:0009991 127 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
sensory perception GO:0007600 245 0.015
fat cell differentiation GO:0045444 160 0.015
metal ion homeostasis GO:0055065 189 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
cellularization GO:0007349 1 0.015
muscle tissue development GO:0060537 308 0.015
nuclear import GO:0051170 95 0.015
cell type specific apoptotic process GO:0097285 268 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
carbohydrate metabolic process GO:0005975 230 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
regulation of protein targeting GO:1903533 61 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
cellular response to external stimulus GO:0071496 88 0.015
regulation of protein secretion GO:0050708 82 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
lymphocyte proliferation GO:0046651 164 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
protein ubiquitination GO:0016567 171 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
positive regulation of cell activation GO:0050867 158 0.015
monocarboxylic acid metabolic process GO:0032787 191 0.014
regulation of response to wounding GO:1903034 189 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.014
notch signaling pathway GO:0007219 71 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
positive regulation of cell development GO:0010720 237 0.014
positive regulation of secretion GO:0051047 130 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
maintenance of location GO:0051235 89 0.014
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.014
regulation of cell projection organization GO:0031344 206 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
leukocyte homeostasis GO:0001776 79 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
negative regulation of t cell activation GO:0050868 65 0.014
lipid localization GO:0010876 126 0.014
angiogenesis GO:0001525 201 0.014
germ cell development GO:0007281 185 0.014
cation transmembrane transport GO:0098655 266 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
stem cell differentiation GO:0048863 268 0.014
erk1 and erk2 cascade GO:0070371 77 0.014
regulation of muscle system process GO:0090257 80 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
regulation of hydrolase activity GO:0051336 246 0.014
regulation of protein processing GO:0070613 96 0.014
regulation of interleukin 8 production GO:0032677 3 0.014
renal system development GO:0072001 225 0.014
peptide metabolic process GO:0006518 46 0.014
atp catabolic process GO:0006200 55 0.014
peptide transport GO:0015833 133 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
negative regulation of immune effector process GO:0002698 55 0.014
regulated secretory pathway GO:0045055 32 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
adaptive immune response GO:0002250 155 0.013
regulation of homeostatic process GO:0032844 182 0.013
calcium ion homeostasis GO:0055074 127 0.013
defense response to gram positive bacterium GO:0050830 50 0.013
spermatid development GO:0007286 108 0.013
rhythmic process GO:0048511 174 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
nucleoside catabolic process GO:0009164 206 0.013
positive regulation of organelle organization GO:0010638 128 0.013
regulation of chemokine secretion GO:0090196 4 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
respiratory system development GO:0060541 190 0.013
multicellular organismal signaling GO:0035637 91 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
forebrain development GO:0030900 302 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.012
positive regulation of nervous system development GO:0051962 221 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
cellular protein catabolic process GO:0044257 155 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
intracellular protein transport GO:0006886 204 0.012
acute inflammatory response GO:0002526 41 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of tube size GO:0035150 57 0.012
purine containing compound catabolic process GO:0072523 213 0.012
positive regulation of protein secretion GO:0050714 52 0.012
cellular lipid metabolic process GO:0044255 323 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
positive regulation of vasoconstriction GO:0045907 4 0.012
organic acid biosynthetic process GO:0016053 86 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
negative regulation of molecular function GO:0044092 258 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.012
ribose phosphate metabolic process GO:0019693 291 0.012
immunoglobulin mediated immune response GO:0016064 69 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
tumor necrosis factor production GO:0032640 50 0.012
antimicrobial peptide biosynthetic process GO:0002777 2 0.012
regulation of t cell proliferation GO:0042129 92 0.012
positive regulation of immune effector process GO:0002699 107 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
positive regulation of protein transport GO:0051222 93 0.012
organ regeneration GO:0031100 2 0.012
single fertilization GO:0007338 82 0.012
amide transport GO:0042886 138 0.012
regulation of peptidase activity GO:0052547 96 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
regulation of cell migration GO:0030334 219 0.012
negative regulation of protein transport GO:0051224 46 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
regulation of cell cycle GO:0051726 281 0.011
wound healing GO:0042060 157 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
positive regulation of chemokine production GO:0032722 22 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
anatomical structure homeostasis GO:0060249 145 0.011
negative regulation of cell development GO:0010721 169 0.011
neuronal action potential GO:0019228 54 0.011
nucleotide catabolic process GO:0009166 217 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
small molecule biosynthetic process GO:0044283 132 0.011
regulation of anatomical structure size GO:0090066 178 0.011
tissue homeostasis GO:0001894 115 0.011
positive regulation of chemokine secretion GO:0090197 4 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
cellular amide metabolic process GO:0043603 58 0.011
fertilization GO:0009566 127 0.011
regulation of chemokine production GO:0032642 30 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
actin cytoskeleton organization GO:0030036 220 0.011
interleukin 8 secretion GO:0072606 3 0.011
regulation of ossification GO:0030278 112 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
negative regulation of proteolysis GO:0045861 74 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
positive regulation of homeostatic process GO:0032846 64 0.011
protein targeting GO:0006605 143 0.011
defense response to virus GO:0051607 68 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
muscle cell differentiation GO:0042692 261 0.010
response to peptide GO:1901652 136 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
spermatid differentiation GO:0048515 115 0.010
humoral immune response GO:0006959 57 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
positive regulation of interleukin 8 production GO:0032757 2 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
transmission of nerve impulse GO:0019226 76 0.010
female sex differentiation GO:0046660 84 0.010
negative regulation of secretion GO:0051048 61 0.010
leukocyte degranulation GO:0043299 27 0.010
response to insulin GO:0032868 100 0.010
cell growth GO:0016049 130 0.010
regulation of transmembrane transport GO:0034762 128 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
immunoglobulin production GO:0002377 73 0.010
protein import GO:0017038 101 0.010
negative regulation of defense response GO:0031348 77 0.010
epithelial cell proliferation GO:0050673 174 0.010
negative regulation of nervous system development GO:0051961 156 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
purine ribonucleoside catabolic process GO:0046130 205 0.010
regulation of protein import into nucleus GO:0042306 52 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
establishment of organelle localization GO:0051656 122 0.010
blood coagulation GO:0007596 76 0.010
mitotic cell cycle process GO:1903047 159 0.010
pattern recognition receptor signaling pathway GO:0002221 47 0.010

Dram1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
immune system disease DOID:2914 0 0.021
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.013
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
disease by infectious agent DOID:0050117 0 0.012