Mus musculus

0 known processes

Dram2

VDNA-damage regulated autophagy modulator 2

(Aliases: 2010305N14Rik,AI647667,2610318G18Rik,Tmem77)

Dram2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid biosynthetic process GO:0008610 179 0.685
glycerolipid metabolic process GO:0046486 122 0.622
small molecule biosynthetic process GO:0044283 132 0.381
glycerophospholipid metabolic process GO:0006650 71 0.347
organic hydroxy compound metabolic process GO:1901615 203 0.301
organophosphate catabolic process GO:0046434 232 0.285
amine metabolic process GO:0009308 45 0.283
cellular lipid metabolic process GO:0044255 323 0.278
phospholipid metabolic process GO:0006644 87 0.259
nucleoside triphosphate metabolic process GO:0009141 230 0.243
glycosyl compound catabolic process GO:1901658 206 0.210
cellular amine metabolic process GO:0044106 44 0.194
cellular biogenic amine metabolic process GO:0006576 28 0.192
membrane fusion GO:0061025 38 0.178
organic anion transport GO:0015711 137 0.174
organonitrogen compound catabolic process GO:1901565 264 0.160
guanosine containing compound catabolic process GO:1901069 144 0.155
vesicle organization GO:0016050 60 0.154
purine ribonucleotide catabolic process GO:0009154 208 0.147
glycerolipid biosynthetic process GO:0045017 50 0.136
lipid transport GO:0006869 98 0.134
organic cyclic compound catabolic process GO:1901361 295 0.133
lipid catabolic process GO:0016042 69 0.130
organophosphate ester transport GO:0015748 28 0.130
membrane organization GO:0061024 245 0.126
organic hydroxy compound biosynthetic process GO:1901617 77 0.120
nitrogen compound transport GO:0071705 271 0.119
purine ribonucleoside metabolic process GO:0046128 241 0.117
phospholipid catabolic process GO:0009395 5 0.115
regulation of intracellular transport GO:0032386 159 0.114
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.113
carbohydrate derivative catabolic process GO:1901136 231 0.112
nucleotide metabolic process GO:0009117 332 0.109
cellular ketone metabolic process GO:0042180 84 0.108
aromatic compound catabolic process GO:0019439 286 0.104
vesicle localization GO:0051648 86 0.097
alcohol metabolic process GO:0006066 116 0.095
cellular amino acid metabolic process GO:0006520 103 0.092
fatty acid metabolic process GO:0006631 121 0.091
gtp catabolic process GO:0006184 143 0.091
establishment of vesicle localization GO:0051650 81 0.087
nucleoside phosphate metabolic process GO:0006753 338 0.083
neurotransmitter secretion GO:0007269 62 0.083
nucleoside metabolic process GO:0009116 246 0.082
glycerolipid catabolic process GO:0046503 16 0.082
nucleotide catabolic process GO:0009166 217 0.078
nucleobase containing small molecule metabolic process GO:0055086 352 0.078
purine containing compound catabolic process GO:0072523 213 0.077
monocarboxylic acid metabolic process GO:0032787 191 0.072
nucleoside phosphate catabolic process GO:1901292 222 0.072
ribonucleoside triphosphate catabolic process GO:0009203 199 0.072
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
alcohol biosynthetic process GO:0046165 43 0.070
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.069
guanosine containing compound metabolic process GO:1901068 144 0.066
small molecule catabolic process GO:0044282 71 0.066
regulation of neurotransmitter levels GO:0001505 87 0.066
ribonucleoside triphosphate metabolic process GO:0009199 220 0.065
regulation of cellular catabolic process GO:0031329 242 0.065
Human
cdp choline pathway GO:0006657 2 0.062
nucleoside triphosphate catabolic process GO:0009143 205 0.060
cellular lipid catabolic process GO:0044242 52 0.060
synaptic transmission GO:0007268 329 0.060
regulation of secretion by cell GO:1903530 249 0.059
regulation of secretion GO:0051046 274 0.057
vacuole organization GO:0007033 38 0.057
anion transport GO:0006820 177 0.056
ribonucleotide catabolic process GO:0009261 208 0.053
positive regulation of gtp catabolic process GO:0033126 85 0.053
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.053
positive regulation of nucleotide catabolic process GO:0030813 88 0.052
glycosyl compound metabolic process GO:1901657 246 0.051
establishment of protein localization to vacuole GO:0072666 4 0.050
purine nucleotide catabolic process GO:0006195 211 0.049
immune effector process GO:0002252 321 0.049
blood coagulation GO:0007596 76 0.049
ribonucleoside metabolic process GO:0009119 245 0.048
heterocycle catabolic process GO:0046700 280 0.047
insulin secretion GO:0030073 89 0.046
purine nucleoside metabolic process GO:0042278 241 0.044
neurotransmitter transport GO:0006836 76 0.043
nucleoside catabolic process GO:0009164 206 0.043
gtp metabolic process GO:0046039 144 0.043
lipid localization GO:0010876 126 0.041
regulation of vesicle mediated transport GO:0060627 139 0.041
ribose phosphate metabolic process GO:0019693 291 0.041
positive regulation of protein autophosphorylation GO:0031954 4 0.039
regulation of neuron projection development GO:0010975 169 0.039
phosphatidylethanolamine metabolic process GO:0046337 2 0.039
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
response to oxidative stress GO:0006979 123 0.038
peptidyl tyrosine phosphorylation GO:0018108 143 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
lytic vacuole organization GO:0080171 21 0.037
establishment of synaptic vesicle localization GO:0097480 57 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
organophosphate biosynthetic process GO:0090407 122 0.036
protein localization to vacuole GO:0072665 4 0.035
negative regulation of synaptic vesicle transport GO:1902804 3 0.035
positive regulation of hydrolase activity GO:0051345 148 0.035
triglyceride metabolic process GO:0006641 51 0.035
regulation of purine nucleotide catabolic process GO:0033121 122 0.035
regulation of neuron differentiation GO:0045664 281 0.035
purine containing compound metabolic process GO:0072521 311 0.034
regulation of steroid biosynthetic process GO:0050810 26 0.034
phospholipid transport GO:0015914 21 0.033
ethanolamine containing compound metabolic process GO:0042439 18 0.033
glycerophospholipid biosynthetic process GO:0046474 32 0.033
protein localization to membrane GO:0072657 108 0.033
positive regulation of gtpase activity GO:0043547 85 0.033
organelle localization GO:0051640 179 0.033
peroxisomal transport GO:0043574 4 0.033
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.032
organic acid transport GO:0015849 101 0.032
positive regulation of protein modification process GO:0031401 299 0.031
glycerophospholipid catabolic process GO:0046475 5 0.030
fatty acid alpha oxidation GO:0001561 2 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.029
regulation of lymphocyte activation GO:0051249 240 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
peptidyl tyrosine modification GO:0018212 145 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
ribonucleotide metabolic process GO:0009259 291 0.027
regulation of nucleoside metabolic process GO:0009118 130 0.027
steroid metabolic process GO:0008202 119 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
defense response to other organism GO:0098542 197 0.027
carboxylic acid biosynthetic process GO:0046394 86 0.027
cellular response to growth factor stimulus GO:0071363 197 0.027
adaptive immune response GO:0002250 155 0.026
positive regulation of secretion GO:0051047 130 0.026
ion transmembrane transport GO:0034220 361 0.025
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.025
transmembrane transport GO:0055085 412 0.025
lipid homeostasis GO:0055088 63 0.025
leukocyte mediated immunity GO:0002443 174 0.024
regulation of lipid metabolic process GO:0019216 118 0.024
activation of immune response GO:0002253 138 0.024
rab protein signal transduction GO:0032482 1 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
protein localization to peroxisome GO:0072662 4 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
positive regulation of nervous system development GO:0051962 221 0.024
hormone secretion GO:0046879 128 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
coagulation GO:0050817 78 0.023
calcium ion dependent exocytosis GO:0017156 35 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
regulation of synaptic plasticity GO:0048167 87 0.023
exocytosis GO:0006887 121 0.023
positive regulation of secretion by cell GO:1903532 114 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
response to growth factor GO:0070848 198 0.022
axon target recognition GO:0007412 4 0.022
regulation of exocytosis GO:0017157 61 0.022
regulation of synaptic vesicle exocytosis GO:2000300 11 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
regulation of toll like receptor 4 signaling pathway GO:0034143 4 0.022
regulation of endocytic recycling GO:2001135 3 0.022
peptide secretion GO:0002790 114 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
vesicle fusion GO:0006906 16 0.021
regulation of multi organism process GO:0043900 111 0.021
regulation of gtp catabolic process GO:0033124 113 0.021
skin development GO:0043588 220 0.021
response to organonitrogen compound GO:0010243 246 0.021
monocarboxylic acid biosynthetic process GO:0072330 61 0.021
negative regulation of glycoprotein metabolic process GO:1903019 3 0.021
cellular response to lipid GO:0071396 145 0.021
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.020
response to inorganic substance GO:0010035 96 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
negative regulation of neurotransmitter transport GO:0051589 7 0.020
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.020
regulation of leukocyte mediated immunity GO:0002703 104 0.020
retrograde transport endosome to golgi GO:0042147 2 0.020
oxidation reduction process GO:0055114 342 0.020
meiotic cell cycle GO:0051321 122 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.019
plasma membrane organization GO:0007009 90 0.019
regulation of neuronal synaptic plasticity GO:0048168 30 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
meiotic nuclear division GO:0007126 115 0.019
synaptic vesicle localization GO:0097479 59 0.019
protein localization to plasma membrane GO:0072659 57 0.019
regulation of t cell activation GO:0050863 170 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
protein targeting to vacuole GO:0006623 3 0.018
positive regulation of transferase activity GO:0051347 167 0.018
regulation of transferase activity GO:0051338 263 0.018
cytokine production GO:0001816 319 0.018
protein targeting GO:0006605 143 0.018
blood vessel morphogenesis GO:0048514 285 0.018
regulation of neurotransmitter secretion GO:0046928 29 0.018
golgi to endosome transport GO:0006895 3 0.017
regulation of hormone levels GO:0010817 211 0.017
neuromuscular synaptic transmission GO:0007274 16 0.017
amide transport GO:0042886 138 0.017
maintenance of location GO:0051235 89 0.017
response to light stimulus GO:0009416 135 0.017
lysosome organization GO:0007040 21 0.016
microtubule based process GO:0007017 236 0.016
regulation of cell shape GO:0008360 39 0.016
cellular homeostasis GO:0019725 240 0.016
regulation of steroid metabolic process GO:0019218 39 0.016
golgi to plasma membrane protein transport GO:0043001 10 0.016
organic acid biosynthetic process GO:0016053 86 0.016
negative regulation of exocytosis GO:0045920 12 0.016
cellular chemical homeostasis GO:0055082 215 0.016
establishment of organelle localization GO:0051656 122 0.016
bone morphogenesis GO:0060349 78 0.016
intracellular protein transport GO:0006886 204 0.016
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
leukocyte differentiation GO:0002521 342 0.016
somitogenesis GO:0001756 69 0.016
cellular protein complex assembly GO:0043623 116 0.015
cellular response to sterol depletion GO:0071501 4 0.015
positive regulation of neuron projection development GO:0010976 79 0.015
rap protein signal transduction GO:0032486 3 0.015
progesterone biosynthetic process GO:0006701 1 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
regulation of protein transport GO:0051223 163 0.015
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.015
cholesterol metabolic process GO:0008203 56 0.015
epidermis development GO:0008544 187 0.015
regulation of cell migration GO:0030334 219 0.015
leukocyte proliferation GO:0070661 172 0.015
sterol metabolic process GO:0016125 58 0.014
synaptic vesicle transport GO:0048489 57 0.014
lymphocyte proliferation GO:0046651 164 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.014
regulation of membrane lipid distribution GO:0097035 16 0.014
angiogenesis GO:0001525 201 0.014
adherens junction organization GO:0034332 28 0.014
positive regulation of insulin secretion GO:0032024 26 0.014
response to drug GO:0042493 75 0.014
cell adhesion GO:0007155 329 0.014
single organism cell adhesion GO:0098602 156 0.014
mapk cascade GO:0000165 281 0.014
nuclear division GO:0000280 158 0.014
monocarboxylic acid catabolic process GO:0072329 27 0.014
carboxylic acid transport GO:0046942 100 0.014
sphingosine metabolic process GO:0006670 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
cell junction organization GO:0034330 77 0.014
membrane protein intracellular domain proteolysis GO:0031293 1 0.014
cholesterol homeostasis GO:0042632 44 0.013
regulation of membrane potential GO:0042391 192 0.013
acylglycerol metabolic process GO:0006639 55 0.013
response to radiation GO:0009314 165 0.013
regulation of cell motility GO:2000145 236 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
endocytosis GO:0006897 168 0.013
lipid modification GO:0030258 65 0.013
stem cell development GO:0048864 219 0.013
positive regulation of lipid biosynthetic process GO:0046889 18 0.013
vesicle docking GO:0048278 7 0.013
hemostasis GO:0007599 78 0.013
t cell activation GO:0042110 289 0.013
fatty acid beta oxidation GO:0006635 16 0.013
epithelial cell proliferation GO:0050673 174 0.013
autophagy GO:0006914 45 0.013
Human
positive regulation of protein phosphorylation GO:0001934 242 0.012
cation homeostasis GO:0055080 212 0.012
cation transport GO:0006812 399 0.012
amino acid transport GO:0006865 61 0.012
establishment of protein localization to peroxisome GO:0072663 4 0.012
immune response activating signal transduction GO:0002757 116 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of lipid biosynthetic process GO:0046890 54 0.012
homeostasis of number of cells GO:0048872 210 0.012
negative regulation of neuron death GO:1901215 98 0.012
peptide hormone secretion GO:0030072 109 0.012
sterol transport GO:0015918 38 0.012
monocarboxylic acid transport GO:0015718 44 0.012
developmental maturation GO:0021700 193 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
positive regulation of immune effector process GO:0002699 107 0.012
ossification GO:0001503 216 0.012
mitotic sister chromatid cohesion GO:0007064 1 0.012
protein targeting to peroxisome GO:0006625 4 0.012
phosphatidylcholine biosynthetic process GO:0006656 8 0.012
chemotaxis GO:0006935 247 0.011
retina development in camera type eye GO:0060041 119 0.011
regulation of mapk cascade GO:0043408 248 0.011
phagolysosome assembly GO:0001845 3 0.011
c21 steroid hormone biosynthetic process GO:0006700 3 0.011
endomembrane system organization GO:0010256 147 0.011
regulation of neuron death GO:1901214 134 0.011
synaptic vesicle exocytosis GO:0016079 26 0.011
sphingolipid metabolic process GO:0006665 45 0.011
regulation of organelle organization GO:0033043 289 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
protein catabolic process GO:0030163 221 0.011
intracellular cholesterol transport GO:0032367 3 0.011
neutral lipid metabolic process GO:0006638 57 0.011
cargo loading into vesicle GO:0035459 3 0.011
macromolecule catabolic process GO:0009057 281 0.011
regulation of removal of superoxide radicals GO:2000121 4 0.011
pigmentation GO:0043473 71 0.011
golgi vesicle transport GO:0048193 30 0.011
regulation of protein localization GO:0032880 231 0.011
phospholipid biosynthetic process GO:0008654 36 0.011
metal ion homeostasis GO:0055065 189 0.010
cell junction assembly GO:0034329 52 0.010
response to organic cyclic compound GO:0014070 198 0.010
activation of innate immune response GO:0002218 56 0.010
myeloid leukocyte activation GO:0002274 83 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
b cell activation GO:0042113 161 0.010
regulation of b cell activation GO:0050864 81 0.010
transmission of nerve impulse GO:0019226 76 0.010
regulation of lymphocyte proliferation GO:0050670 117 0.010
positive regulation of plasminogen activation GO:0010756 2 0.010
steroid biosynthetic process GO:0006694 47 0.010
regulation of fatty acid metabolic process GO:0019217 28 0.010
synaptic vesicle priming GO:0016082 8 0.010
regulation of cellular response to growth factor stimulus GO:0090287 82 0.010

Dram2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.155
inherited metabolic disorder DOID:655 0 0.122
sensory system disease DOID:0050155 0 0.049
disease of anatomical entity DOID:7 0 0.049
eye and adnexa disease DOID:1492 0 0.049
nervous system disease DOID:863 0 0.049
eye disease DOID:5614 0 0.049
retinal disease DOID:5679 0 0.036
retinal degeneration DOID:8466 0 0.036