Mus musculus

26 known processes

Derl2

Der1-like domain family, member 2

(Aliases: RP23-83I13.8,CGI-101,MGC11613,F-lana,BC005682,Derlin-2,Flana)

Derl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sphingolipid biosynthetic process GO:0030148 26 0.128
membrane lipid biosynthetic process GO:0046467 32 0.105
response to topologically incorrect protein GO:0035966 25 0.100
Human
lipid biosynthetic process GO:0008610 179 0.059
intra golgi vesicle mediated transport GO:0006891 1 0.055
organonitrogen compound biosynthetic process GO:1901566 192 0.040
apoptotic signaling pathway GO:0097190 306 0.033
nitrogen compound transport GO:0071705 271 0.033
cellular amino acid metabolic process GO:0006520 103 0.031
cellular macromolecule catabolic process GO:0044265 206 0.031
Human
regulation of hormone levels GO:0010817 211 0.030
regulation of organelle organization GO:0033043 289 0.030
lateral inhibition GO:0046331 1 0.030
macromolecule catabolic process GO:0009057 281 0.029
Human
male gamete generation GO:0048232 285 0.029
retrograde vesicle mediated transport golgi to er GO:0006890 1 0.029
er nucleus signaling pathway GO:0006984 27 0.029
Human
ceramide metabolic process GO:0006672 31 0.029
sphingolipid metabolic process GO:0006665 45 0.027
modification dependent protein catabolic process GO:0019941 133 0.026
Human
cation homeostasis GO:0055080 212 0.026
positive regulation of growth GO:0045927 104 0.025
Human
transmembrane transport GO:0055085 412 0.024
membrane organization GO:0061024 245 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
amine metabolic process GO:0009308 45 0.024
regulation of protein localization GO:0032880 231 0.024
leukocyte differentiation GO:0002521 342 0.024
spermatogenesis GO:0007283 284 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
Human
cellular amine metabolic process GO:0044106 44 0.024
immune effector process GO:0002252 321 0.023
response to unfolded protein GO:0006986 21 0.023
Human
lymphocyte mediated immunity GO:0002449 139 0.023
cytoplasmic transport GO:0016482 234 0.023
protein localization to organelle GO:0033365 185 0.022
membrane lipid metabolic process GO:0006643 53 0.022
cellular lipid metabolic process GO:0044255 323 0.022
regulation of cellular catabolic process GO:0031329 242 0.021
positive regulation of t cell activation GO:0050870 101 0.021
regulation of cytokine production GO:0001817 266 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.020
Human
protein catabolic process GO:0030163 221 0.020
Human
carbohydrate derivative catabolic process GO:1901136 231 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
carbohydrate metabolic process GO:0005975 230 0.019
cation transmembrane transport GO:0098655 266 0.019
establishment of protein localization to membrane GO:0090150 54 0.019
positive regulation of protein modification process GO:0031401 299 0.018
endomembrane system organization GO:0010256 147 0.018
heterocycle catabolic process GO:0046700 280 0.018
cation transport GO:0006812 399 0.018
cellular homeostasis GO:0019725 240 0.018
regulation of proteolysis GO:0030162 164 0.018
aromatic compound catabolic process GO:0019439 286 0.018
cellular response to biotic stimulus GO:0071216 92 0.018
mapk cascade GO:0000165 281 0.018
lymphocyte differentiation GO:0030098 242 0.018
cellular ketone metabolic process GO:0042180 84 0.018
intracellular protein transport GO:0006886 204 0.017
ion transmembrane transport GO:0034220 361 0.017
regulation of secretion by cell GO:1903530 249 0.017
leukocyte mediated immunity GO:0002443 174 0.017
regulation of cell activation GO:0050865 289 0.017
regulation of secretion GO:0051046 274 0.017
muscle cell differentiation GO:0042692 261 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
regulation of cellular amine metabolic process GO:0033238 20 0.016
small molecule biosynthetic process GO:0044283 132 0.016
metal ion homeostasis GO:0055065 189 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
carboxylic acid biosynthetic process GO:0046394 86 0.016
gland development GO:0048732 330 0.016
multicellular organism growth GO:0035264 161 0.016
renal system development GO:0072001 225 0.016
peptidyl amino acid modification GO:0018193 336 0.016
cellular protein catabolic process GO:0044257 155 0.016
Human
inorganic ion transmembrane transport GO:0098660 234 0.016
regulation of cellular component biogenesis GO:0044087 181 0.015
organelle localization GO:0051640 179 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
cellular chemical homeostasis GO:0055082 215 0.015
steroid metabolic process GO:0008202 119 0.015
positive regulation of secretion GO:0051047 130 0.015
regulation of t cell activation GO:0050863 170 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
sequestering of metal ion GO:0051238 19 0.015
urogenital system development GO:0001655 261 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
protein ubiquitination GO:0016567 171 0.015
protein localization to membrane GO:0072657 108 0.014
oxidation reduction process GO:0055114 342 0.014
regulation of cell projection organization GO:0031344 206 0.014
organelle fission GO:0048285 170 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
purine containing compound metabolic process GO:0072521 311 0.014
t cell activation GO:0042110 289 0.014
hormone secretion GO:0046879 128 0.014
protein maturation GO:0051604 176 0.014
endoplasmic reticulum unfolded protein response GO:0030968 19 0.014
Human
vesicle organization GO:0016050 60 0.014
cytokine production GO:0001816 319 0.014
regulation of cellular response to stress GO:0080135 159 0.014
regulation of cell migration GO:0030334 219 0.014
nucleotide metabolic process GO:0009117 332 0.014
response to nutrient levels GO:0031667 109 0.013
positive regulation of cell activation GO:0050867 158 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
regulation of transferase activity GO:0051338 263 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of cell motility GO:2000145 236 0.013
meiotic cell cycle GO:0051321 122 0.013
cellular response to external stimulus GO:0071496 88 0.013
peptide transport GO:0015833 133 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
organelle assembly GO:0070925 177 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of cell cycle GO:0051726 281 0.012
positive regulation of cytokine production GO:0001819 174 0.012
regulation of anatomical structure size GO:0090066 178 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
t cell differentiation GO:0030217 174 0.012
positive regulation of transferase activity GO:0051347 167 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
negative regulation of molecular function GO:0044092 258 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
compound eye development GO:0048749 1 0.012
sequestering of calcium ion GO:0051208 18 0.012
regulation of homeostatic process GO:0032844 182 0.012
nuclear division GO:0000280 158 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
vacuole organization GO:0007033 38 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
glycosyl compound metabolic process GO:1901657 246 0.011
regulation of neuron differentiation GO:0045664 281 0.011
organic acid biosynthetic process GO:0016053 86 0.011
protein targeting GO:0006605 143 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.011
positive regulation of cell death GO:0010942 224 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of mapk cascade GO:0043408 248 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
maintenance of location GO:0051235 89 0.011
visual learning GO:0008542 44 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
alcohol biosynthetic process GO:0046165 43 0.011
carbohydrate homeostasis GO:0033500 128 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
response to organic cyclic compound GO:0014070 198 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
cellular response to lipid GO:0071396 145 0.011
multicellular organismal signaling GO:0035637 91 0.011
response to organonitrogen compound GO:0010243 246 0.011
plasma membrane organization GO:0007009 90 0.011
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
anion transport GO:0006820 177 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
b cell activation GO:0042113 161 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
interleukin 8 production GO:0032637 4 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
divalent inorganic cation transport GO:0072511 178 0.010
positive regulation of nervous system development GO:0051962 221 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
microtubule based process GO:0007017 236 0.010
regulation of protein catabolic process GO:0042176 108 0.010
response to starvation GO:0042594 65 0.010
positive regulation of cell motility GO:2000147 116 0.010
mitochondrion organization GO:0007005 134 0.010
ribose phosphate metabolic process GO:0019693 291 0.010
organonitrogen compound catabolic process GO:1901565 264 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
respiratory tube development GO:0030323 167 0.010
regulation of kinase activity GO:0043549 249 0.010
neuron death GO:0070997 154 0.010
respiratory system development GO:0060541 190 0.010
response to endoplasmic reticulum stress GO:0034976 53 0.010
Human
regulation of cilium assembly GO:1902017 7 0.010
cell adhesion GO:0007155 329 0.010
peptide hormone secretion GO:0030072 109 0.010
membrane fusion GO:0061025 38 0.010
developmental maturation GO:0021700 193 0.010
ceramide biosynthetic process GO:0046513 20 0.010
cell division GO:0051301 120 0.010
circulatory system process GO:0003013 197 0.010

Derl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.015
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.011
disease of cellular proliferation DOID:14566 0 0.011