Mus musculus

30 known processes

Clic1

chloride intracellular channel 1

(Aliases: Clcp,G6)

Clic1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.595
regulation of actin filament based process GO:0032970 99 0.495
myosin filament organization GO:0031033 3 0.409
regulation of actin filament polymerization GO:0030833 38 0.409
arp2 3 complex mediated actin nucleation GO:0034314 3 0.385
actin polymerization or depolymerization GO:0008154 54 0.375
membrane organization GO:0061024 245 0.339
regulation of hydrolase activity GO:0051336 246 0.321
regulation of actin filament length GO:0030832 45 0.267
myosin filament assembly GO:0031034 2 0.265
cation homeostasis GO:0055080 212 0.208
Mouse
muscle cell development GO:0055001 133 0.191
endocytosis GO:0006897 168 0.183
cellular component assembly involved in morphogenesis GO:0010927 139 0.180
regulation of actin cytoskeleton organization GO:0032956 84 0.168
engulfment of apoptotic cell GO:0043652 3 0.154
phagocytosis GO:0006909 66 0.153
regulation of vesicle mediated transport GO:0060627 139 0.150
negative regulation of endocytosis GO:0045806 12 0.149
actin filament organization GO:0007015 113 0.142
circulatory system process GO:0003013 197 0.131
angiogenesis GO:0001525 201 0.129
Mouse
homeostasis of number of cells GO:0048872 210 0.128
regulation of secretion GO:0051046 274 0.128
muscle contraction GO:0006936 101 0.127
regulation of peptidase activity GO:0052547 96 0.126
positive regulation of actin filament polymerization GO:0030838 26 0.123
cell type specific apoptotic process GO:0097285 268 0.123
protein maturation GO:0051604 176 0.120
cellular protein complex assembly GO:0043623 116 0.118
actin filament polymerization GO:0030041 44 0.109
leukocyte homeostasis GO:0001776 79 0.108
myeloid cell differentiation GO:0030099 233 0.107
muscle cell differentiation GO:0042692 261 0.105
negative regulation of cellular protein metabolic process GO:0032269 247 0.103
plasma membrane organization GO:0007009 90 0.102
t cell activation GO:0042110 289 0.099
actomyosin structure organization GO:0031032 56 0.098
endomembrane system organization GO:0010256 147 0.098
ion transmembrane transport GO:0034220 361 0.098
Human
regulation of actin nucleation GO:0051125 4 0.096
membrane fusion GO:0061025 38 0.096
neural precursor cell proliferation GO:0061351 121 0.095
organelle fusion GO:0048284 28 0.094
regulation of organelle organization GO:0033043 289 0.092
vesicle fusion GO:0006906 16 0.091
striated muscle cell development GO:0055002 125 0.090
apoptotic signaling pathway GO:0097190 306 0.089
negative regulation of molecular function GO:0044092 258 0.087
membrane raft assembly GO:0001765 3 0.084
protein polymerization GO:0051258 57 0.084
heterocycle catabolic process GO:0046700 280 0.084
regulation of homeostatic process GO:0032844 182 0.082
ameboidal type cell migration GO:0001667 128 0.081
positive regulation of secretion GO:0051047 130 0.079
meiotic nuclear division GO:0007126 115 0.078
blood coagulation GO:0007596 76 0.076
Human
chemotaxis GO:0006935 247 0.076
antigen receptor mediated signaling pathway GO:0050851 64 0.072
apoptotic mitochondrial changes GO:0008637 48 0.072
vesicle organization GO:0016050 60 0.071
cellular response to dna damage stimulus GO:0006974 207 0.071
muscle tissue development GO:0060537 308 0.069
meiotic cell cycle GO:0051321 122 0.069
positive regulation of programmed cell death GO:0043068 218 0.068
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.067
leukocyte proliferation GO:0070661 172 0.066
lipid transport GO:0006869 98 0.066
regulation of ion transport GO:0043269 215 0.064
muscle system process GO:0003012 141 0.063
regulation of cellular component size GO:0032535 121 0.063
negative regulation of phagocytosis GO:0050765 4 0.063
cardiac muscle contraction GO:0060048 32 0.063
divalent metal ion transport GO:0070838 172 0.063
cell adhesion GO:0007155 329 0.061
Human
leukocyte migration GO:0050900 124 0.061
protein processing GO:0016485 163 0.060
positive regulation of cell death GO:0010942 224 0.060
response to acid chemical GO:0001101 111 0.059
regulation of apoptotic signaling pathway GO:2001233 197 0.059
immune effector process GO:0002252 321 0.058
regulation of proteolysis GO:0030162 164 0.058
striated muscle myosin thick filament assembly GO:0071688 1 0.057
synaptic transmission GO:0007268 329 0.056
intrinsic apoptotic signaling pathway GO:0097193 132 0.056
positive regulation of apoptotic signaling pathway GO:2001235 95 0.056
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.056
organelle fission GO:0048285 170 0.055
cation transport GO:0006812 399 0.055
nuclear division GO:0000280 158 0.055
sequestering of metal ion GO:0051238 19 0.055
regulation of membrane potential GO:0042391 192 0.054
positive regulation of cellular component biogenesis GO:0044089 94 0.054
regulation of cell motility GO:2000145 236 0.054
positive regulation of organelle organization GO:0010638 128 0.052
negative regulation of protein metabolic process GO:0051248 282 0.052
positive regulation of protein complex assembly GO:0031334 45 0.052
positive regulation of myeloid cell apoptotic process GO:0033034 4 0.051
tissue migration GO:0090130 68 0.051
regulation of neutrophil apoptotic process GO:0033029 1 0.049
lymphocyte proliferation GO:0046651 164 0.049
regulation of protein complex assembly GO:0043254 83 0.048
metal ion homeostasis GO:0055065 189 0.048
nitrogen compound transport GO:0071705 271 0.048
positive regulation of cytoskeleton organization GO:0051495 49 0.047
transmembrane transport GO:0055085 412 0.046
Human
regulation of cell cycle GO:0051726 281 0.046
positive regulation of neutrophil apoptotic process GO:0033031 1 0.046
mapk cascade GO:0000165 281 0.046
tube formation GO:0035148 140 0.045
fibrinolysis GO:0042730 3 0.045
regulation of endopeptidase activity GO:0052548 89 0.045
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.044
embryonic epithelial tube formation GO:0001838 130 0.044
lamellipodium organization GO:0097581 29 0.044
forebrain development GO:0030900 302 0.044
purine ribonucleoside metabolic process GO:0046128 241 0.043
nucleoside triphosphate catabolic process GO:0009143 205 0.043
calcium ion transport GO:0006816 159 0.043
single organismal cell cell adhesion GO:0016337 131 0.043
Human
leukocyte apoptotic process GO:0071887 71 0.043
regulation of cell cycle process GO:0010564 160 0.042
negative regulation of cellular amine metabolic process GO:0033239 1 0.042
organic cyclic compound catabolic process GO:1901361 295 0.042
sequestering of calcium ion GO:0051208 18 0.041
divalent inorganic cation homeostasis GO:0072507 138 0.041
purine ribonucleoside catabolic process GO:0046130 205 0.041
calcium ion homeostasis GO:0055074 127 0.040
response to uv GO:0009411 44 0.040
mitotic cell cycle process GO:1903047 159 0.040
t cell proliferation GO:0042098 120 0.040
regulation of protein localization GO:0032880 231 0.040
protein localization to organelle GO:0033365 185 0.039
negative regulation of cellular component organization GO:0051129 194 0.038
cellular response to abiotic stimulus GO:0071214 56 0.038
lymphocyte homeostasis GO:0002260 64 0.038
cell chemotaxis GO:0060326 81 0.038
regulation of system process GO:0044057 200 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
dna metabolic process GO:0006259 303 0.037
myeloid cell homeostasis GO:0002262 114 0.037
regulation of cytoskeleton organization GO:0051493 122 0.037
purine containing compound catabolic process GO:0072523 213 0.037
negative regulation of transferase activity GO:0051348 85 0.037
protein localization to membrane GO:0072657 108 0.036
regulation of endocytosis GO:0030100 69 0.036
regulation of neuron apoptotic process GO:0043523 122 0.036
establishment of protein localization to membrane GO:0090150 54 0.036
positive regulation of peptide secretion GO:0002793 33 0.036
release of sequestered calcium ion into cytosol GO:0051209 42 0.036
leukocyte mediated immunity GO:0002443 174 0.035
neural tube development GO:0021915 160 0.035
blood circulation GO:0008015 195 0.035
cellular ketone metabolic process GO:0042180 84 0.035
maintenance of location GO:0051235 89 0.035
microtubule cytoskeleton organization GO:0000226 157 0.035
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
actin filament depolymerization GO:0030042 15 0.034
germ cell development GO:0007281 185 0.034
cellular response to antibiotic GO:0071236 4 0.034
integrin biosynthetic process GO:0045112 1 0.034
positive regulation of vesicle fusion GO:0031340 2 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
small gtpase mediated signal transduction GO:0007264 97 0.034
regulation of blood pressure GO:0008217 93 0.034
microtubule based process GO:0007017 236 0.034
t cell apoptotic process GO:0070231 39 0.033
morphogenesis of embryonic epithelium GO:0016331 159 0.033
cytokinetic process GO:0032506 2 0.033
epithelium migration GO:0090132 63 0.033
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.033
ribonucleotide catabolic process GO:0009261 208 0.033
regulation of cellular component biogenesis GO:0044087 181 0.033
gtp metabolic process GO:0046039 144 0.033
regulation of protein maturation GO:1903317 96 0.032
regulation of heart contraction GO:0008016 77 0.032
telencephalon development GO:0021537 186 0.032
cytoplasmic transport GO:0016482 234 0.032
intracellular protein transport GO:0006886 204 0.032
regulation of actin polymerization or depolymerization GO:0008064 45 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
negative regulation of homeostatic process GO:0032845 71 0.031
aromatic compound catabolic process GO:0019439 286 0.031
blood vessel morphogenesis GO:0048514 285 0.031
Mouse
muscle fiber development GO:0048747 76 0.031
regulation of muscle system process GO:0090257 80 0.031
b cell activation GO:0042113 161 0.030
cellular metal ion homeostasis GO:0006875 151 0.030
negative regulation of lymphocyte activation GO:0051250 91 0.030
lymphocyte apoptotic process GO:0070227 54 0.030
amine metabolic process GO:0009308 45 0.030
cell killing GO:0001906 67 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
mitotic cell cycle GO:0000278 195 0.030
oxidation reduction process GO:0055114 342 0.029
regulation of anatomical structure size GO:0090066 178 0.029
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.029
regulation of lymphocyte apoptotic process GO:0070228 41 0.029
cardiac muscle tissue development GO:0048738 130 0.029
cellular ion homeostasis GO:0006873 165 0.029
Mouse
glycosyl compound metabolic process GO:1901657 246 0.029
developmental maturation GO:0021700 193 0.029
regulation of integrin biosynthetic process GO:0045113 1 0.029
regulation of neuron death GO:1901214 134 0.029
regulation of cell activation GO:0050865 289 0.029
coagulation GO:0050817 78 0.028
Human
leukocyte differentiation GO:0002521 342 0.028
positive regulation of homeostatic process GO:0032846 64 0.028
nucleotide catabolic process GO:0009166 217 0.028
regulation of intracellular transport GO:0032386 159 0.028
divalent inorganic cation transport GO:0072511 178 0.028
positive regulation of nervous system development GO:0051962 221 0.028
neural tube formation GO:0001841 108 0.028
leukocyte chemotaxis GO:0030595 69 0.028
regulation of lamellipodium assembly GO:0010591 3 0.027
wound healing GO:0042060 157 0.027
Human
wnt signaling pathway GO:0016055 188 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
Mouse
cellular amino acid metabolic process GO:0006520 103 0.027
plasma cell differentiation GO:0002317 3 0.027
organic acid transport GO:0015849 101 0.027
cell activation involved in immune response GO:0002263 126 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
nucleoside metabolic process GO:0009116 246 0.027
retrograde transport endosome to golgi GO:0042147 2 0.027
peptide transport GO:0015833 133 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
regulation of metal ion transport GO:0010959 106 0.027
organelle assembly GO:0070925 177 0.026
t cell mediated immunity GO:0002456 50 0.026
reactive oxygen species metabolic process GO:0072593 84 0.026
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
neuron death GO:0070997 154 0.026
g1 s transition of mitotic cell cycle GO:0000082 57 0.026
protein oligomerization GO:0051259 67 0.026
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 2 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
regulation of binding GO:0051098 111 0.026
regulation of calcium ion transport GO:0051924 69 0.026
positive regulation of hydrolase activity GO:0051345 148 0.025
organic anion transport GO:0015711 137 0.025
negative regulation of kinase activity GO:0033673 81 0.025
t cell homeostasis GO:0043029 35 0.025
oocyte anterior posterior axis specification GO:0007314 2 0.025
cell aging GO:0007569 35 0.025
cellular calcium ion homeostasis GO:0006874 119 0.025
positive regulation of rho gtpase activity GO:0032321 41 0.025
regulation of calcium ion transport into cytosol GO:0010522 31 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
negative regulation of proteolysis GO:0045861 74 0.025
dna catabolic process endonucleolytic GO:0000737 15 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
regulation of cellular ketone metabolic process GO:0010565 66 0.024
protein localization to plasma membrane GO:0072659 57 0.024
skeletal muscle organ development GO:0060538 163 0.024
platelet activation GO:0030168 40 0.024
Human
negative regulation of cell cycle GO:0045786 123 0.024
multicellular organismal signaling GO:0035637 91 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
glycosyl compound catabolic process GO:1901658 206 0.024
multi multicellular organism process GO:0044706 109 0.024
cellular protein catabolic process GO:0044257 155 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
regulation of secretion by cell GO:1903530 249 0.023
canonical wnt signaling pathway GO:0060070 130 0.023
regulation of nucleotide catabolic process GO:0030811 122 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
notch signaling pathway GO:0007219 71 0.023
organophosphate catabolic process GO:0046434 232 0.023
dephosphorylation GO:0016311 129 0.023
neutrophil apoptotic process GO:0001781 3 0.023
myotube cell development GO:0014904 60 0.023
male gamete generation GO:0048232 285 0.023
regulation of interleukin 8 production GO:0032677 3 0.023
cytosolic calcium ion transport GO:0060401 48 0.022
ossification GO:0001503 216 0.022
regulation of mitotic cell cycle phase transition GO:1901990 73 0.022
ras protein signal transduction GO:0007265 77 0.022
ribonucleoside metabolic process GO:0009119 245 0.022
leukocyte mediated cytotoxicity GO:0001909 62 0.022
pallium development GO:0021543 120 0.022
cytochrome complex assembly GO:0017004 3 0.022
regulation of leukocyte apoptotic process GO:2000106 56 0.022
regulation of protein processing GO:0070613 96 0.022
cellular amine metabolic process GO:0044106 44 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
chronological cell aging GO:0001300 1 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
dendrite development GO:0016358 115 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
organelle localization GO:0051640 179 0.021
epithelial tube formation GO:0072175 130 0.021
mitochondrion organization GO:0007005 134 0.020
regulation of transferase activity GO:0051338 263 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
negative regulation of peptidase activity GO:0010466 46 0.020
regulation of lymphocyte proliferation GO:0050670 117 0.020
homotypic cell cell adhesion GO:0034109 28 0.020
Human
macromolecule catabolic process GO:0009057 281 0.020
positive regulation of proteolysis GO:0045862 85 0.020
regulation of cell projection organization GO:0031344 206 0.020
striated muscle tissue development GO:0014706 293 0.020
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.020
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.020
cellular response to oxidative stress GO:0034599 76 0.020
lymphocyte differentiation GO:0030098 242 0.020
peptide secretion GO:0002790 114 0.020
positive regulation of peptidase activity GO:0010952 49 0.020
positive regulation of endopeptidase activity GO:0010950 43 0.020
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.019
anion transport GO:0006820 177 0.019
Human
negative regulation of cell migration GO:0030336 59 0.019
uropod organization GO:0032796 2 0.019
regulation of response to wounding GO:1903034 189 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.019
protein catabolic process GO:0030163 221 0.019
striated muscle contraction GO:0006941 45 0.019
activation of immune response GO:0002253 138 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.019
cellular chemical homeostasis GO:0055082 215 0.019
Mouse
single organism cell adhesion GO:0098602 156 0.019
Human
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
apoptotic cell clearance GO:0043277 17 0.019
regulation of immunological synapse formation GO:2000520 2 0.019
negative regulation of protein modification process GO:0031400 163 0.018
regulation of peptide transport GO:0090087 91 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
regulation of peptide secretion GO:0002791 77 0.018
regulation of kinase activity GO:0043549 249 0.018
positive regulation of gtpase activity GO:0043547 85 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
female gamete generation GO:0007292 74 0.018
release of cytochrome c from mitochondria GO:0001836 23 0.018
positive regulation of leukocyte apoptotic process GO:2000108 21 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regulation of protein kinase activity GO:0045859 232 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
amide transport GO:0042886 138 0.018
positive regulation of cell activation GO:0050867 158 0.018
monocarboxylic acid transport GO:0015718 44 0.018
myoblast differentiation GO:0045445 52 0.017
skeletal muscle fiber development GO:0048741 58 0.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
Mouse
purine nucleoside metabolic process GO:0042278 241 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
myotube differentiation GO:0014902 105 0.017
response to muscle stretch GO:0035994 1 0.017
response to light stimulus GO:0009416 135 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.017
positive regulation of t cell activation GO:0050870 101 0.017
nucleotide metabolic process GO:0009117 332 0.017
actin cytoskeleton reorganization GO:0031532 21 0.017
adaptive immune response GO:0002250 155 0.017
establishment of organelle localization GO:0051656 122 0.017
negative regulation of vesicle fusion GO:0031339 1 0.017
response to organonitrogen compound GO:0010243 246 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.017
learning or memory GO:0007611 148 0.017
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.017
primary neural tube formation GO:0014020 95 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
meiotic cell cycle process GO:1903046 77 0.016
regulation of apoptotic dna fragmentation GO:1902510 5 0.016
zymogen activation GO:0031638 41 0.016
protein localization to nucleus GO:0034504 121 0.016
regulation of neuron differentiation GO:0045664 281 0.016
camera type eye development GO:0043010 266 0.016
Mouse
peptidyl amino acid modification GO:0018193 336 0.016
oocyte axis specification GO:0007309 2 0.016
response to radiation GO:0009314 165 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
glucose homeostasis GO:0042593 128 0.016
regulation of heart rate by chemical signal GO:0003062 4 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
long chain fatty acid transport GO:0015909 15 0.016
cell division GO:0051301 120 0.016
regulation of blood circulation GO:1903522 93 0.016
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.016
cellular lipid metabolic process GO:0044255 323 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of cell adhesion GO:0030155 154 0.016
regulation of neuronal synaptic plasticity GO:0048168 30 0.016
regulation of muscle tissue development GO:1901861 97 0.015
negative regulation of protein processing GO:0010955 79 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
regulation of relaxation of muscle GO:1901077 8 0.015
positive regulation of cell projection organization GO:0031346 95 0.015
i kappab kinase nf kappab signaling GO:0007249 85 0.015
gtp catabolic process GO:0006184 143 0.015
t cell receptor signaling pathway GO:0050852 46 0.015
negative regulation of cell motility GO:2000146 61 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
carbohydrate metabolic process GO:0005975 230 0.015
regulation of cell migration GO:0030334 219 0.015
regulation of mapk cascade GO:0043408 248 0.015
regulation of protein heterodimerization activity GO:0043497 2 0.015
negative regulation of immunological synapse formation GO:2000521 1 0.015
carboxylic acid transport GO:0046942 100 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
actin filament branching GO:0090135 1 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
compound eye development GO:0048749 1 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
defense response to other organism GO:0098542 197 0.015
spermatid differentiation GO:0048515 115 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.015
respiratory system development GO:0060541 190 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.014
Mouse
regulation of synaptic plasticity GO:0048167 87 0.014
regulation of t cell proliferation GO:0042129 92 0.014
regulation of interleukin 1 alpha secretion GO:0050705 3 0.014
lung development GO:0030324 164 0.014
dna catabolic process GO:0006308 19 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
development of primary sexual characteristics GO:0045137 143 0.014
regulation of rho gtpase activity GO:0032319 58 0.014
activation of cysteine type endopeptidase activity GO:0097202 27 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
positive regulation of ras gtpase activity GO:0032320 65 0.014
cognition GO:0050890 149 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of lamellipodium morphogenesis GO:2000392 1 0.014
cerebral cortex development GO:0021987 86 0.014
negative regulation of organelle organization GO:0010639 90 0.014
cellular response to hexose stimulus GO:0071331 47 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
multi organism behavior GO:0051705 62 0.014
interleukin 1 alpha secretion GO:0050703 3 0.014
neuron apoptotic process GO:0051402 142 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
alpha beta t cell differentiation GO:0046632 69 0.013
regulation of skeletal muscle fiber development GO:0048742 36 0.013
response to endoplasmic reticulum stress GO:0034976 53 0.013
positive regulation of ion transport GO:0043270 65 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
regulation of neuron projection development GO:0010975 169 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
regulation of cell projection assembly GO:0060491 38 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
immune response regulating signaling pathway GO:0002764 125 0.013
regulation of body fluid levels GO:0050878 162 0.013
Human
sensory system development GO:0048880 3 0.013
skeletal myofibril assembly GO:0014866 4 0.013
inflammatory response GO:0006954 244 0.013
response to amino acid GO:0043200 37 0.013
positive regulation of cell cycle process GO:0090068 61 0.013
monosaccharide metabolic process GO:0005996 106 0.013
platelet aggregation GO:0070527 20 0.013
Human
regulation of cell substrate adhesion GO:0010810 73 0.013
axonogenesis GO:0007409 274 0.013
dna repair GO:0006281 107 0.013
determination of left right symmetry GO:0007368 80 0.013
negative regulation of protein maturation GO:1903318 79 0.013
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.013
positive regulation of cell development GO:0010720 237 0.013
mitotic cytokinesis GO:0000281 4 0.013
negative regulation of neuron death GO:1901215 98 0.013
cellular response to topologically incorrect protein GO:0035967 25 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
regulation of vesicle fusion GO:0031338 6 0.013
establishment of tissue polarity GO:0007164 28 0.013
regulation of t cell activation GO:0050863 170 0.013
regulation of integrin mediated signaling pathway GO:2001044 8 0.013
sensory organ morphogenesis GO:0090596 242 0.013
Mouse
cellular glucose homeostasis GO:0001678 52 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
protein homooligomerization GO:0051260 43 0.013
detection of muscle stretch GO:0035995 1 0.013
regulation of interleukin 1 alpha production GO:0032650 4 0.013
hemostasis GO:0007599 78 0.013
Human
neural tube closure GO:0001843 90 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
negative regulation of cell activation GO:0050866 111 0.012

Clic1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
immune system disease DOID:2914 0 0.025
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.020
epilepsy syndrome DOID:1826 0 0.017
central nervous system disease DOID:331 0 0.017
brain disease DOID:936 0 0.017
electroclinical syndrome DOID:0050701 0 0.017
organ system cancer DOID:0050686 0 0.015
primary immunodeficiency disease DOID:612 0 0.013