|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.986
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.973
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.972
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.969
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.961
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.938
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.932
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.926
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.925
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.916
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.912
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.897
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.874
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.866
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.864
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.859
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.849
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.847
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.836
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.832
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.830
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.823
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.818
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.814
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.812
|
Human |
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.801
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.793
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.790
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.780
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.773
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.770
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.748
|
Zebrafish |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.731
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.729
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.721
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.700
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.698
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.671
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.668
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.655
|
Zebrafish |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.649
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.646
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.629
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.627
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.626
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.619
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.617
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.606
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.604
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.598
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.592
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.592
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.556
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.555
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.554
|
|
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.550
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.547
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.539
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.534
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.534
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.525
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.518
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.518
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.514
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.511
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.505
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.504
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.502
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.498
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.492
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.485
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.485
|
Zebrafish |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.480
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.471
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.469
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.469
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.469
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.467
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.462
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.456
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.451
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.450
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.444
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.443
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.439
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.433
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
3 |
0.431
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.423
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.419
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.416
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.414
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.411
|
Human |
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.402
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.402
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.401
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.399
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.397
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.395
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.390
|
Zebrafish |
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.388
|
Human |
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.386
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.379
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.379
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.375
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.372
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.370
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.370
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.370
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.365
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.361
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.359
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.357
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.344
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.342
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.341
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.337
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.335
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.334
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.333
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.330
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.327
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.326
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.324
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.324
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.323
|
Human |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.322
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.322
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.319
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.315
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.311
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.311
|
Zebrafish |
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.310
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.302
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.293
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.291
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.291
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.288
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.284
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.283
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.283
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.280
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.279
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.279
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.272
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.272
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.270
|
Human Zebrafish |
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.270
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.270
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.268
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.263
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.261
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.261
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.261
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.260
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.256
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.253
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.251
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.251
|
Human |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.250
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.245
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.242
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.242
|
|
|
|
positive regulation of interferon beta production
|
GO:0032728 |
8 |
0.242
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.239
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.238
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.236
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.235
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.235
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.234
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.234
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.233
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.232
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.232
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.228
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.225
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.223
|
|
|
|
hair follicle cell proliferation
|
GO:0071335 |
3 |
0.223
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.219
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.218
|
Human |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.218
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.218
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.217
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.216
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.215
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.215
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.212
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.210
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.210
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.209
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.208
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.207
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.207
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.205
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.205
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.205
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.205
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.204
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.201
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.199
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.199
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.199
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.195
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.195
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.192
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.191
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.188
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.188
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.186
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.185
|
Human |
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.184
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.182
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.181
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.176
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.174
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.174
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.173
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.173
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.170
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.169
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.169
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.166
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.164
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.164
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.163
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.163
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.163
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.162
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.162
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.162
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.161
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.161
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.160
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.159
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.159
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.158
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.158
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.158
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.157
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.157
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.155
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.155
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.154
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.153
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.152
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.152
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.150
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.148
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.146
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.145
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.145
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.144
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.144
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
10 |
0.144
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.144
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.143
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.143
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.143
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.142
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.142
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.141
|
|
|
|
humoral immune response mediated by circulating immunoglobulin
|
GO:0002455 |
14 |
0.140
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.140
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.139
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.139
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.138
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.137
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.137
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.136
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.134
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.134
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.134
|
|
|
|
negative regulation of defense response to virus by host
|
GO:0050689 |
1 |
0.134
|
|
|
|
neutrophil differentiation
|
GO:0030223 |
3 |
0.133
|
Zebrafish |
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.132
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.132
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.131
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.131
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.130
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.130
|
|
|
|
regulation of glycoprotein biosynthetic process
|
GO:0010559 |
12 |
0.129
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.129
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.128
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.128
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.126
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.125
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.124
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.124
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.124
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.123
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.122
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.121
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.121
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.120
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.120
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.120
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.120
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.119
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.119
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.119
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.118
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.118
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.118
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.117
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.117
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.116
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.116
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.116
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.115
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.114
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.114
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.114
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.112
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.112
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.111
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.110
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.108
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.107
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.107
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.106
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.105
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.105
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.104
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.104
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.104
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.104
|
|
|
|
histamine production involved in inflammatory response
|
GO:0002349 |
1 |
0.103
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.103
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.102
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.102
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.102
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.101
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.101
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.101
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.101
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.100
|
|
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.099
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.099
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.098
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.098
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.098
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.097
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.096
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.096
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.095
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.094
|
|
|
|
negative regulation of humoral immune response mediated by circulating immunoglobulin
|
GO:0002924 |
3 |
0.094
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.093
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.093
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.093
|
Zebrafish |
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.093
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.093
|
Human Zebrafish |
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.093
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.092
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.092
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.092
|
|
|
|
regulation of neutrophil differentiation
|
GO:0045658 |
2 |
0.092
|
Zebrafish |
|
|
action potential
|
GO:0001508 |
78 |
0.092
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.091
|
|
|
|
transdifferentiation
|
GO:0060290 |
1 |
0.091
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.091
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.091
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.090
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.090
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.089
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.089
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.089
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.088
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.088
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.088
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.088
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.088
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.088
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.087
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.087
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.087
|
Human |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.087
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.087
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.086
|
Human Zebrafish |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.086
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.085
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.085
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.085
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.084
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.084
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.084
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.083
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.083
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.083
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.083
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.083
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.082
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.082
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.081
|
|
|
|
negative regulation of interferon beta biosynthetic process
|
GO:0045358 |
1 |
0.081
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.080
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.080
|
|
|
|
toll like receptor 9 signaling pathway
|
GO:0034162 |
6 |
0.080
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.080
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.079
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.079
|
Human |
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.079
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.078
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.078
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.078
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.077
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.077
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.077
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.076
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.076
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.076
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.076
|
|
|
|
cd8 positive alpha beta t cell differentiation
|
GO:0043374 |
9 |
0.076
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.075
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.075
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.075
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.075
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.074
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.074
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.074
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.074
|
|
|
|
positive regulation of toll like receptor 9 signaling pathway
|
GO:0034165 |
2 |
0.073
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.073
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.073
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.073
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.072
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.072
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.072
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.071
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.071
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.070
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.070
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.070
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.070
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.070
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.069
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.068
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.068
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.068
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.068
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.068
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.068
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.068
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.067
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.067
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.067
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.066
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.066
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.066
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.066
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.066
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.066
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.065
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.065
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.065
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.064
|
Human |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.063
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.063
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.063
|
|
|
|
interferon beta production
|
GO:0032608 |
16 |
0.063
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.063
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.063
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.063
|
|
|
|
metanephros development
|
GO:0001656 |
79 |
0.062
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.062
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.061
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.061
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.061
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.061
|
Human |
|
|
cell growth
|
GO:0016049 |
130 |
0.061
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.061
|
|
|
|
positive regulation of keratinocyte proliferation
|
GO:0010838 |
4 |
0.061
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.060
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.060
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.060
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.060
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.060
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.060
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.059
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.059
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.059
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.059
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.059
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.058
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.058
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.058
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.058
|
|
|
|
mrna transcription from rna polymerase ii promoter
|
GO:0042789 |
4 |
0.058
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.058
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.057
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.057
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.056
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.056
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.056
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.056
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.056
|
|
|
|
regulation of hair follicle cell proliferation
|
GO:0071336 |
2 |
0.056
|
|
